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HOME / INGREDIENTS / Ammonium perfluorooctanoate (apfo)


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Ammonium Perfluorooctanoate (APFO)

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SYNONYMS

AMMONIUM PERFLUOROOCTANOATE (APFO)

Common Concerns

See how this product scores for common concerns.

  • No Data
    Asthma / Respiratory
  • No Data
    Skin Allergies & Irritation
  • HIGH
    Developmental & Reproductive Toxicity
  • MODERATE
    Cancer
  • No Data
    Environment


Top Scoring Factors

Evidence of developmental/endocrine/reproductive effects; biodegradation; blood-related effects


Ingredient concerns

  • CONCERNS
Health Issue Level of Concern Source
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A draft risk assessment from the U.S. Environmental Protection Agency reported that chronic exposure to perfluorooctanoic acids and salts can affect blood.

high

U.S. Environmental Protection Agency (EPA). 2005. Draft risk assessment of the potential human health effects associated with exposure to perfluorooctanoic acid and salts. SAB Review Draft.

A draft risk assessment from the U.S. Environmental Protection Agency reported that chronic exposure to perfluorooctanoic acids and salts caused reproductive or developmental effects in lab animals.

high

U.S. Environmental Protection Agency (EPA). 2005. Draft risk assessment of the potential human health effects associated with exposure to perfluorooctanoic acid and salts. SAB Review Draft.

A U.S. Environmental Protection Agency fact sheet finds perfluorooctanoic acid and perfluorooctane sulfonate to be persistent pollutants.

high

U.S. Environmental Protection Agency (EPA). 2012. Emerging Contaminants – Perfluorooctane Sulfonate (PFOS) and Perfluorooctanoic Acid (PFOA). Emerging Contaminants Fact Sheet.

A draft risk assessment from the U.S. Environmental Protection Agency reported that perfluorooctanoic acids and salts had acute oral toxicity LD50s as low as 250 mg/kg body weight.

moderate

U.S. Environmental Protection Agency (EPA). 2005. Draft risk assessment of the potential human health effects associated with exposure to perfluorooctanoic acid and salts. SAB Review Draft.

A Science Advisory Board review of the U.S. Environmental Protection Agency draft risk assessment of perfluorooctanoic acid and its salts finds these substances to be probable human carcinogens.

moderate

U.S. Environmental Protection Agency (EPA). 2006. SAB Review of EPA’s Draft Risk Assessment of Potential Human Health Effects Associated with PFOA and Its Salts.

A draft risk assessment from the U.S. Environmental Protection Agency found evidence that perfluorooctanoic acids and salts may change hormone levels in humans.

moderate

U.S. Environmental Protection Agency (EPA). 2005. Draft risk assessment of the potential human health effects associated with exposure to perfluorooctanoic acid and salts. SAB Review Draft.

A draft risk assessment from the U.S. Environmental Protection Agency reported that chronic exposure to perfluorooctanoic acids and salts can harm the liver.

moderate

U.S. Environmental Protection Agency (EPA). 2005. Draft risk assessment of the potential human health effects associated with exposure to perfluorooctanoic acid and salts. SAB Review Draft.

A draft risk assessment from the U.S. Environmental Protection Agency found suggestive evidence that perfluorooctanoic acids and salts can cause cancer; this designation has not been finalized.

moderate

U.S. Environmental Protection Agency (EPA). 2005. Draft risk assessment of the potential human health effects associated with exposure to perfluorooctanoic acid and salts. SAB Review Draft.

A draft risk assessment from the U.S. Environmental Protection Agency reported that chronic exposure to perfluorooctanoic acids and salts may be toxic to the immune system.

moderate

U.S. Environmental Protection Agency (EPA). 2005. Draft risk assessment of the potential human health effects associated with exposure to perfluorooctanoic acid and salts. SAB Review Draft.

A draft risk assessment from the U.S. Environmental Protection Agency reported that perfluorooctanoic acids and salts were not mutagenic.

low

U.S. Environmental Protection Agency (EPA). 2005. Draft risk assessment of the potential human health effects associated with exposure to perfluorooctanoic acid and salts. SAB Review Draft.



Understanding scores

EWG provides information on cleaning product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any.

HOW WE DETERMINE SCORES

Hazard score

The Healthy Cleaning ingredient hazard score, from A to F, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED® mark means a product meets EWG’s strictest criteria for transparency and health.

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