developmentb
D

D&C RED NO. 17 (CI 26100)

 
This substance ranges from C to D depending on concentration/usage.
Asthma/Respiratory
 
Some Concern
 
Skin Allergies &
Irritation
 
Some Concern
 
Developmental &
Reproductive Toxicity
 
Some Concern
 
Cancer
 
Some Concern
 
Environment
 
No Data, Some Concern
 
Top scoring factors: Evidence of developmental/endocrine/reproductive effects; respiratory effects; cancer
D&C Red No. 17 (CI 26100) can be found in 3 products.
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Evidence

Health issue
 
Level of Concern
 
Source
A review article reports that this substance can be transformed into carcinogenic metabolites, including by the human skin and gut microbiomes.
 
some
 
Teresa M. Fonovich. 2013. Sudan dyes: are they dangerous for human health?. Drug and chemical toxicology 36(3), 343-52.
This substance disrupts endocrine receptor expression in vivo.
 
some
 
Zein Shaban, Samir El-Shazly, Shawky Abdelhady, Ibrahim Fattouh, Kaampwe Muzandu, Mayumi Ishizuka, Kazuhiro Kimura, Akio Kazusaka & Shoichi Fujita. 2004. Down regulation of hepatic PPARalpha function by AhR ligand. The Journal of veterinary medical science 66(11), 1377-86.
may cause respiratory irritation
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Substance disrupts function of liver enzymes.
 
some
 
European Commission, Scientific Committee on Consumer Products (SCCP). 2005. Opinion on the use of CI 26100 (CI Solvent Red 23) as a colorant in cosmetic products.
Causes skin irritation
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Causes serious eye damage
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Substances has marginal irritant properties to skin and mucous membranes.
 
some
 
European Commission, Scientific Committee on Consumer Products (SCCP). 2005. Opinion on the use of CI 26100 (CI Solvent Red 23) as a colorant in cosmetic products.
Not classifiable as to its carcinogenicity to humans
 
low
 
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
Not classifiable as to its carcinogenicity to humans
 
low
 
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
Studies of carcinogenic potential to date have been inadequate.
 
low
 
European Commission, Scientific Committee on Consumer Products (SCCP). 2005. Opinion on the use of CI 26100 (CI Solvent Red 23) as a colorant in cosmetic products.
Low acute oral toxicity.
 
low
 
European Commission, Scientific Committee on Consumer Products (SCCP). 2005. Opinion on the use of CI 26100 (CI Solvent Red 23) as a colorant in cosmetic products.

Impurities

Health issue
 
Level of Concern
 
Source
Impurity: P-PHENYLENEDIAMINE
Very toxic to aquatic life
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: P-PHENYLENEDIAMINE
Very toxic to aquatic life with long lasting effects
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: P-PHENYLENEDIAMINE
Toxic if swallowed
Only in: Household Cleaners
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: P-PHENYLENEDIAMINE
Toxic in contact with skin
Only in: Household Cleaners
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: P-PHENYLENEDIAMINE
Toxic if inhaled
Only in: Household Cleaners
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: P-PHENYLENEDIAMINE
causes damage to organs
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: P-PHENYLENEDIAMINE
May cause an allergic skin reaction
Only in: Household Cleaners
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: P-PHENYLENEDIAMINE
skin sensitization
 
some
 
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: P-PHENYLENEDIAMINE
upper respiratory tract irritation
 
some
 
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: P-PHENYLENEDIAMINE
Harmful if swallowed
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: P-PHENYLENEDIAMINE
May cause an allergic skin reaction
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Impurity: P-PHENYLENEDIAMINE
Causes serious eye irritation
Only in: Household Cleaners
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: P-PHENYLENEDIAMINE
NTP Toxcast scored 1.5-2.5
 
some
 
National Toxicology Program (NTP): EWG Toxcast Analysis
Impurity: P-PHENYLENEDIAMINE
Not classifiable as to its carcinogenicity to humans
 
low
 
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
Impurity: P-PHENYLENEDIAMINE
not classifiable as a human carcinogen
 
low
 
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: P-PHENYLENEDIAMINE
Not known to cause asthma
 
low
 
Association of Occupational and Environmental Clinics (AOEC): AOEC Exposure Code List (2020 Update)
 
 
About the ratings About the ratings
EWG provides information on cleaning product ingredients from the published scientific... continue reading →
EWG provides information on cleaning product ingredients from published scientific literature, to supplement incomplete data available from companies and the government. The ratings indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors that determine actual health risks, if any. (Hide)
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