developmentb
D

OCTYLISOTHIAZOLINONE

 

Unacceptable: EWG VERIFIED products cannot contain this ingredient.

This substance ranges from C to D depending on concentration/usage.

Asthma/Respiratory
 
No Data, Some Concern
 
Skin Allergies &
Irritation
 
Some Concern
 
Developmental &
Reproductive Toxicity
 
Low Concern
 
Cancer
 
No Data, Some Concern
 
Environment
 
No Data, Some Concern
 
Top scoring factors: Evidence of acute aquatic toxicity; skin irritation/allergies/damage; developmental/endocrine/reproductive effects
OCTYLISOTHIAZOLINONE can be found in 79 products.
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Evidence

Health issue
 
Level of Concern
 
Source
A U.S. Environmental Protection Agency review classified octylisothiazolinone as very highly toxic to aquatic life.
 
high
 
U.S. Environmental Protection Agency. 2007. Reregistration Eligibility Decision for 2-Octyl-3 (2H)-isothiazolone (OIT).
A U.S. Environmental Protection Agency review classified octylisothiazolinone as a skin sensitizer.
 
some
 
U.S. Environmental Protection Agency. 2007. Reregistration Eligibility Decision for 2-Octyl-3 (2H)-isothiazolone (OIT).
NTP Toxcast scored 1.5-2.5
 
some
 
National Toxicology Program (NTP): EWG Toxcast Analysis
A U.S. Environmental Protection Agency review found no evidence that octylisothiazolinone causes developmental effects.
 
low
 
U.S. Environmental Protection Agency. 2007. Reregistration Eligibility Decision for 2-Octyl-3 (2H)-isothiazolone (OIT).
A U.S. Environmental Protection Agency review found no evidence that octylisothiazolinone is mutagenic.
 
low
 
U.S. Environmental Protection Agency. 2007. Reregistration Eligibility Decision for 2-Octyl-3 (2H)-isothiazolone (OIT).
 
 
About the ratings About the ratings
EWG provides information on cleaning product ingredients from the published scientific... continue reading →
EWG provides information on cleaning product ingredients from published scientific literature, to supplement incomplete data available from companies and the government. The ratings indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors that determine actual health risks, if any. (Hide)
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