Evidence
Health issue
Level of Concern
Source
Quaternary ammonium compounds
Very toxic to aquatic life
Very toxic to aquatic life
high
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Quaternary ammonium compounds
Causes severe skin burns and eye damage
Only in: Oven Cleaner; Drain Opener/Clog Remover; Hard Water Stain Remover; Toilet Cleaner; Stove Top Cleaner; Household Cleaners
Causes severe skin burns and eye damage
Only in: Oven Cleaner; Drain Opener/Clog Remover; Hard Water Stain Remover; Toilet Cleaner; Stove Top Cleaner; Household Cleaners
high
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Quaternary ammonium compounds
Asthmagen (allergic)
Asthmagen (allergic)
moderate
AOEC Asthmagen list - AOEC
Quaternary ammonium compounds
Harmful if swallowed
Only in: Household Cleaners
Harmful if swallowed
Only in: Household Cleaners
moderate
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Quaternary ammonium compounds
Harmful in contact with skin
Only in: Household Cleaners
Harmful in contact with skin
Only in: Household Cleaners
moderate
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Quaternary ammonium compounds
Asthmagen
Asthmagen
some
AOEC Asthmagen list - AOEC
Quaternary ammonium compounds
Causes severe skin burns and eye damage
Only in: Drain Opener/Clog Remover; Oven Cleaner; Hard Water Stain Remover; Toilet Cleaner; Stove Top Cleaner; Household Cleaners
Causes severe skin burns and eye damage
Only in: Drain Opener/Clog Remover; Oven Cleaner; Hard Water Stain Remover; Toilet Cleaner; Stove Top Cleaner; Household Cleaners
some
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Quaternary ammonium compounds
NTP Toxcast scored 2.5-3.5
NTP Toxcast scored 2.5-3.5
some
EWG Toxcast Analysis - National Toxicology Program (NTP)
Quaternary ammonium compounds
A peer-reviewed publication reports some quaternary ammonium compounds cause reproductive toxicity in animals.
A peer-reviewed publication reports some quaternary ammonium compounds cause reproductive toxicity in animals.
some
Vanessa E. Melin, Travis E. Melin, Brian J. Dessify, Christina T. Nguyen, Caroline S. Shea & Terry C. Hrubec. 2015. Quaternary Ammonium Disinfectants Cause Subfertility in Mice by Targeting both Male and Female Reproductive Processes. Reproductive toxicology (Elmsford, N.Y.).
Quaternary ammonium compounds
A peer-reviewed publication reports some quaternary ammonium compounds cause reproductive toxicity in animals.
A peer-reviewed publication reports some quaternary ammonium compounds cause reproductive toxicity in animals.
some
Vanessa E. Melin, Haritha Potineni, Patricia Hunt, Jodi Griswold, Bill Siems, Stephen R. Werre & Terry C. Hrubec. 2014. Exposure to common quaternary ammonium disinfectants decreases fertility in mice. Reproductive toxicology (Elmsford, N.Y.) 50, 163-70.
