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BHT

BHT
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Overall BHT is of higher concern in food.

The overall ingredient concern is determined by using a weight of evidence evaluation of the known safety or hazards. In calculating an overall ingredient score multiple findings of low concern may lead to an overall moderate concern rating, or multiple moderate concerns may lead to a high concern rating. For more details read EWG's ingredient concern methodology.

Specific concerns for BHT

Concern
 
Level of Concern in Food
 
Source
A peer-reviewed study found this substance caused adverse developmental effects in rats.
 
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C. V. Vorhees, R. E. Butcher, R. L. Brunner & T. J. Sobotka. 1981. Developmental neurobehavioural toxicity of butylated hydroxytoluene in rats. Food and cosmetics toxicology 19(2), 153-62.
This peer-reviewed study reports this substance is a tumor promoter.
 
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Colin T. Shearn, Kristofer S. Fritz & John A. Thompson. 2011. Protein damage from electrophiles and oxidants in lungs of mice chronically exposed to the tumor promoter butylated hydroxytoluene. Chemico-biological interactions 192(3), 278-86.
This peer-reviewed study reports this substance is a tumor promoter.
 
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Haris G. Vikis, Alexander S. Krupnick, Jay W. Tichelaar, Pengyuan Liu, Jihong Zhu, Amy Rymaszewski, Lauren Stein, Andrew Franklin, Andrew E. Gelman & Ming You. 2011. Neutrophils are required for 3-methylcholanthrene-initiated, butylated hydroxytoluene-promoted lung carcinogenesis. Molecular carcinogenesis.
NTP Toxcast scored 3.5-4.5
 
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EWG Toxcast Analysis - National Toxicology Program (NTP)
 

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