On the go? Download our Mobile App

TITLE
share
food categories menu
site menu
 
Learn more
 

RED 40 LAKE

RED 40 LAKE
Title info loading....

Overall RED 40 LAKE is of lower concern in food.

The overall ingredient concern is determined by using a weight of evidence evaluation of the known safety or hazards. In calculating an overall ingredient score multiple findings of low concern may lead to an overall moderate concern rating, or multiple moderate concerns may lead to a high concern rating. For more details read EWG's ingredient concern methodology.

Specific concerns for RED 40 LAKE

Concern
 
Level of Concern in Food
 
Source
EFSA finds that there is "limited evidence" that Allura Red in a mixture with other synthetic colors and sodium benzoate has a "small and statistically significant effect on activity and attention in children selected from the general population."
 
lower
European Food Safety Authority (EFSA). 2009. Scientific Opinion on the re-evaluation of Allura Red AC (E 129) as a food additive. EFSA Journal 7(11), 1327.
EFSA concludes that some sensitive individuals may experience allergic reactions at dose levels within the ADI.
 
lower
European Food Safety Authority (EFSA). 2009. Scientific Opinion on the re-evaluation of Allura Red AC (E 129) as a food additive. EFSA Journal 7(11), 1327.
NTP Toxcast scored 2.5-3.5
 
lower
National Toxicology Program (NTP): EWG Toxcast Analysis
NTP Toxcast scored 2.5-3.5
 
lower
National Toxicology Program (NTP): EWG Toxcast Analysis
A peer-reviewed study reports nervous system effects at the acceptable daily dose for humans.
 
lower
Ali Noorafshan, Maedeh Hashemi, Saied Karbalay-Doust & Fatemeh Karimi. 2018. High dose Allura Red, rather than the ADI dose, induces structural and behavioral changes in the medial prefrontal cortex of rats and taurine can protect it. Acta histochemica 120(6), 586-594.
A peer-reviewed study reports that Red 40 affects the function of an enzyme important for the endocrine system.
 
lower
Kanako Satoh, Rhouichi Nonaka, Fusako Ishikawa, Akio Ogata & Fumiko Nagai. 2008. In vitro screening assay for detecting aromatase activity using rat ovarian microsomes and estrone ELISA. Biological & pharmaceutical bulletin 31(3), 357-62.
Review article concluded that Red 40 caused hypersensitivity reactions.
 
lower
Peer Reviewed Literature: Kobylewski, S. & Jacobson, M.F. 2012. Toxicology of food dyes. International journal of occupational and environmental health 18(3), 220-46.
Some data submitters indicate they consider this substance as Persistent, Bioaccumulative and Toxic
 
lower
European Chemicals Agency (ECHA): GHS Data from ECHA Website

Concerns from impurities

Concern
 
Level of Concern in Food
 
Source
Impurity: ANILINE
Suspected of causing genetic defects
 
lower
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: ANILINE
Suspected of causing cancer
 
lower
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: ANILINE
Causes damage to organs through prolonged or repeated exposure
 
lower
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: ANILINE
Known to cause cancer
 
lower
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
Impurity: 6-METHOXY-M-TOLUIDINE
May cause cancer
 
lower
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: 6-METHOXY-M-TOLUIDINE
Known to cause cancer
 
lower
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
Impurity: 1-NAPHTHYLAMINE
Known to cause cancer
 
lower
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
Impurity: MERCURY
Causes damage to organs through prolonged or repeated exposure
 
lower
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: MERCURY
May damage the unborn child.
 
lower
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: CADMIUM
Suspected of causing genetic defects
 
lower
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: CADMIUM
May cause cancer
 
lower
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: CADMIUM
Causes damage to organs through prolonged or repeated exposure
 
lower
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: CADMIUM
Suspected of damaging fertility.
 
lower
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: CADMIUM
Suspected of damaging the unborn child.
 
lower
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: CADMIUM
Carcinogenic to humans
 
lower
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
Impurity: CADMIUM
Known To Be Human Carcinogen
 
lower
National Toxicology Program (NTP): NTP 14th Report on Carcinogens
Impurity: ANILINE
Probably carcinogenic to humans
 
lower
Environmental Protection Agency (EPA): EPA Integrated Risk Information System (IRIS) - Cancer
Impurity: ANILINE
Probably carcinogenic to humans
 
lower
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
Impurity: 6-METHOXY-M-TOLUIDINE
Reasonably Anticipated To Be Human Carcinogen
 
lower
National Toxicology Program (NTP): NTP 14th Report on Carcinogens
Impurity: CADMIUM
Probably carcinogenic to humans
 
lower
Environmental Protection Agency (EPA): EPA Integrated Risk Information System (IRIS) - Cancer
Impurity: MERCURY
EPA's review of industry submitted toxicity data and the potential for human exposure concludes that this substance poses a high risk for human health.
 
lower
Environmental Protection Agency (EPA): EPA Hazard-Based Prioritizations - Risks
Impurity: 6-METHOXY-M-TOLUIDINE
Possibly carcinogenic to humans
 
lower
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
Impurity: 6-METHOXY-M-TOLUIDINE
NTP Toxcast scored 1.5-2.5
 
lower
National Toxicology Program (NTP): EWG Toxcast Analysis
 

eat well guide

find sustainable food!

The Eat Well Guide helps consumers find locally grown and sustainably produced food. Listings include farms, restaurants, stores, farmers' markets, and CSAs throughout the United States.

Visit the Eat Well Guide

Information

Food Categories:

Search:

Share:

Want more food tips?

Sign up to receive email updates, action alerts, healthy eating tips, promotions to support our work and more from EWG! You can opt out at any time.

Select one:

Consumer Contact Form:

EWG reserves the right to make public any information provided to it by companies. I understand that EWG does not accept any confidential or trade secret information that EWG does not have permission to share publicly. If I am contacting EWG on behalf of a company, by clicking "submit," I affirm that I have the authority to contact EWG on my company's behalf and to provide EWG permission to publicly disseminate all information provided.

Company Contact Form:

I would like to update my product's:







Other inquiries:








EWG reserves the right to make public any information provided to it by companies. I understand that EWG does not accept any confidential or trade secret information that EWG does not have permission to share publicly. If I am contacting EWG on behalf of a company, by clicking "submit," I affirm that I have the authority to contact EWG on my company's behalf and to provide EWG permission to publicly disseminate all information provided.

Get the Guide