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National Drinking Water Database


National Drinking Water Database - Chemical Contaminants

p-Isopropyltoluene


Status: Unregulated - EPA has not established a maximum legal limit in tapwater for this contaminant.

p-Isopropyltoluene is a widely used industrial chemical used in the manufacture of paint, furniture and other consumer goods.

 
Detected
Found above
health guidelines
Found above
legal limit
States
12
-
-
Water utilities
22
-
-
People Served
43,725
-
-

Health Concerns for p-Isopropyltoluene:


p-Isopropyltoluene Exposure by State

Water utilities in 12 states have reported detecting p-Isopropyltoluene in treated tap water since 2004, according to EWG's analysis of water quality data supplied by state water agencies.

StateWater Suppliers with p-Isopropyltoluene contamination
SystemsPopulation
New York620,265
Nebraska16,591
Arkansas16,112
Virginia33,638
Missouri22,844
Wisconsin21,649
Vermont1825
California1665
North Carolina2440
Maryland1378
Alaska1293
Texas125
Total2243,725

The Most Polluted Communities

22 water utilities reported detecting p-Isopropyltoluene in tap water since 2004, according to EWG's analysis of water quality data supplied by state water agencies

Ranked by highest average p-Isopropyltoluene level

RankSystem Population Served Positive test results of total reported tests Average Level
(Range)
1Cedar Hollow Mobile Home Park
Wappingers Falls, NY
2001 of 12.8 ppb
(2.8 ppb)
2Freedom Sanitary District
Kaukauna, WI
1,0001 of 12.5 ppb
(2.5 ppb)
3Collingwood Associates, L.P.
King Of Prussia, NY
3601 of 31.77 ppb
(0 to 5.3 ppb)
4Huslia Public Water Supply
Huslia, AK
2931 of 11 ppb
(1 ppb)
5Jensen's Hyde Park Mobile Home Park
Southington, MD
3781 of 10.6 ppb
(0.6 ppb)
6Bedford Hills/Taconic Corr. Facilities
Bedford Hills, NY
1,1001 of 10.5 ppb
(0.5 ppb)
7Red Mountain S/D
Rougemont, NC
1681 of 10.43 ppb
(0.43 ppb)
8Spring Meadows-Meadow Gate
Warwick, VA
2,2541 of 30.43 ppb
(0 to 1.3 ppb)
9Town of Cape Charles
Cape Charles, VA
1,1341 of 30.4 ppb
(0 to 1.2 ppb)
10Walraven Subdivision
Houston, TX
251 of 30.31 ppb
(0 to 0.92 ppb)

Testing Summary for p-Isopropyltoluene

Are tests routinely required for p-Isopropyltoluene by federal law?No
Water suppliers reporting tests for p-Isopropyltoluene (2004-2009):20,559 of 47,576
Average testing rate for water supplier reporting tests (2004-2009):0.6 per year

Neurotoxicity

Type of concern: Reference:
Limited evidence of toxicity Lam HR, Ladefoged O, Ostergaard G, Lund SP, Simonsen L, 1996
One or more animal studies show brain, nervous system, or behavioral effect effects at high doses RTECS®- Food and Cosmetics Toxicology 1964

Organ system toxicity (non-reproductive)

Type of concern: Reference:
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient) RTECS®- "Vrednie chemichescie veshestva, galogenproisvodnie uglevodorodov" 1990
One or more animal studies show sense organ effects at high doses (low dose studies may be unavailable for this ingredient) RTECS®- Food and Cosmetics Toxicology 1964
One or more animal studies show gastrointestinal effects at high doses (low dose studies may be unavailable for this ingredient) RTECS®- Food and Cosmetics Toxicology 1964
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient) RTECS®- "Vrednie chemichescie veshestva, galogenproisvodnie uglevodorodov" 1990
Classified as not expected to be potentially toxic or harmful Environment Canada Domestic Substance List
Classified as a low human health priority Environment Canada Domestic Substance List

Irritation (skin, eyes, or lungs)

Type of concern: Reference:
One or more animal studies show skin irritation at low doses RTECS®- Food and Cosmetics Toxicology 1974

Ecotoxicology

Type of concern: Reference:
Not suspected to be an environmental toxin Environment Canada Domestic Substance List

Multiple, additive exposure sources

Type of concern: Reference:
Designated as safe for general or specific, limited use in food FDA Everything Added to Food

Persistence and bioaccumulation

Type of concern: Reference:
Not suspected to be persistent Environment Canada Domestic Substance List
Not suspected to be bioaccumulative Environment Canada Domestic Substance List



Government, industry, academic studies and classifications

government/industry list/academic study appears on list as classification(s)
FDA Everything Added to FoodP-CYMENE• Fully up-to-date toxicology information has been sought.
Environment Canada Domestic Substance ListBENZENE, 1-METHYL-4-(1-METHYLETHYL)-•This chemical was NOT flagged by CEPA for further attention. The chemical was flagged for as a low human health priority.
IFRA Fragrance Ingredient ListP-CYMENE•The chemical has been reported as used in fragrance compounds by IFRA affiliated member companies in 2008.
Lam HR, Ladefoged O, Ostergaard G, Lund SP, Simonsen L, 1996P-CYMENEInhalation exposure to p-cymene in laboratory animals was associated with neurotoxicity (reduced density and number of synapses).
RTECS®- "Vrednie chemichescie veshestva, galogenproisvodnie uglevodorodov" 1990PARACYMENE• broad systemic - Broad systemic toxicity (mouse LD50)
RTECS®- Food and Cosmetics Toxicology 1974PARACYMENE• skin - Primary skin irritant (rabbit )
RTECS®- Food and Cosmetics Toxicology 1964PARACYMENE• sense organ - Chromodacyrorrhea (rat LD50)
• gastrointestinal - Hypermotility, diarrhea (rat LD50)
• brain, nervous system, or behavioral effect - Somnolence (general depressed activity) (rat LD50)



references

government/industry list/academic study reference
FDA Everything Added to FoodFDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
Environment Canada Domestic Substance ListEC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
IFRA Fragrance Ingredient ListIFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25
Open scientific literatureLam HR, Ladefoged O, Ostergaard G, Lund SP, Simonsen L. 1996. Four weeks
RTECS®- "Vrednie chemichescie veshestva, galogenproisvodnie uglevodorodov" 1990RTECS®- "Vrednie chemichescie veshestva, galogenproisvodnie uglevodorodov". (Hazardous substances: Galogenated hydrocarbons) Bandman A.L. et al., Chimia, 1990. -,180,1990
RTECS®- Food and Cosmetics Toxicology 1974RTECS®- Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. 12,401,1974
RTECS®- Food and Cosmetics Toxicology 1964RTECS®- Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. 2,327,1964

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