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National Drinking Water Database


National Drinking Water Database - Chemical Contaminants

Trichlorotrifluoroethane


Status: Unregulated - EPA has not established a maximum legal limit in tapwater for this contaminant.

Trichlorotrifluoroethane (Freon 113) is used in industrial applications such as a degreasing or dry cleaning solvent, refrigerant, fire extinguisher component and chemical intermediate; production in the U.S. has been banned since 1996.

 
Detected
Found above
health guidelines
Found above
legal limit
States
3
-
-
Water utilities
15
-
-
People Served
1,029,342
-
-

Health Concerns for Trichlorotrifluoroethane:


Trichlorotrifluoroethane Exposure by State

Water utilities in 3 states have reported detecting Trichlorotrifluoroethane in treated tap water since 2004, according to EWG's analysis of water quality data supplied by state water agencies.

StateWater Suppliers with Trichlorotrifluoroethane contamination
SystemsPopulation
California12874,632
New York2141,400
Wisconsin113,310
Total151,029,342

The Most Polluted Communities

15 water utilities reported detecting Trichlorotrifluoroethane in tap water since 2004, according to EWG's analysis of water quality data supplied by state water agencies

Ranked by highest average Trichlorotrifluoroethane level

RankSystem Population Served Positive test results of total reported tests Average Level
(Range)
1Poplar Comm Service Dist
Poplar, CA
1,9011 of 117.33 ppb
(17.33 ppb)
2Rurban Homes Mutual Water Co.
El Monte, CA
30017 of 2115.43 ppb
(0 to 59.3 ppb)
3Camrosa Water District
Camarillo, CA
27,00016 of 207.88 ppb
(0 to 38.4 ppb)
4Champion Water Mutual
El Monte, CA
25010 of 177.34 ppb
(0 to 18 ppb)
5City of Modesto
Modesto, CA
190,10640 of 2203.4 ppb
(0 to 42 ppb)
6Santa Rosa Mobile Estates
Santa Rosa, CA
4201 of 12.45 ppb
(2.45 ppb)
7Redlands City Mud-Water Div
Redlands, CA
69,3001 of 720.32 ppb
(0 to 23 ppb)
8Great Oaks Wc, Inc.
San Jose, CA
69,7872 of 350.3 ppb
(0 to 6 ppb)
9City of Farmersville
Farmersville, CA
10,2402 of 30.26 ppb
(0 to 0.5 ppb)
10City of Porterville
Porterville, CA
49,4963 of 160.24 ppb
(0 to 2.4 ppb)

Health Based Limits for Trichlorotrifluoroethane

StandardDescriptionLevel
California Public Health GoalsDefined by the State of California Office of Environmental Health Hazard Assessment (OEHHA) as the level of contaminant that is allowed in drinking water. For acutely toxic substances, levels are set at which scientific evidence indicates that no known or anticipated adverse effects on health will occur, plus an adequate margin-of safety. PHGs for carcinogens or other substances which can cause chronic disease shall be based solely on health effects without regard to cost impacts and shall be set at levels which OEHHA has determined do not pose any significant risk to health.4000 ppb

Testing Summary for Trichlorotrifluoroethane

Are tests routinely required for Trichlorotrifluoroethane by federal law?No
Water suppliers reporting tests for Trichlorotrifluoroethane (2004-2009):3,250 of 47,576
Average testing rate for water supplier reporting tests (2004-2009):1.0 per year

Multiple, additive exposure sources

Type of concern: Reference:
Used in food or as an additive with limited or no toxicity information available FDA Everything Added to Food

Organ system toxicity (non-reproductive)

Type of concern: Reference:
Limited evidence of cardiovascular or blood toxicity Klaassen, C, 1996
One or more animal studies show effects at moderate doses (low dose studies may be unavailable for this ingredient) EPA Categorized List of Inert Pesticide Ingredients
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient) EPA Toxic Release Inventory PBTs
One or more animal studies show gastrointestinal effects at high doses (low dose studies may be unavailable for this ingredient) RTECS®- Journal of Medicinal Chemistry 1964
Classified as not expected to be potentially toxic or harmful Environment Canada Domestic Substance List
Classified as a low human health priority Environment Canada Domestic Substance List

Occupational hazards

Type of concern: Reference:
Allowed workplace exposures restricted to high doses RTECS®- TLV/BEI,2006
Allowed workplace exposures restricted to high doses RTECS®- MSHA STANDARD-air: 3,267,1971
Allowed workplace exposures restricted to high doses RTECS®- OSHA PEL (Gen Indu): 29,1910 1994
Allowed workplace exposures restricted to high doses RTECS®- OSHA PEL (Construc): 29,1926 1994
Allowed workplace exposures restricted to high doses RTECS®- OSHA PEL (Shipyard): 29,1915 1993
Allowed workplace exposures restricted to high doses RTECS®- OSHA PEL (Fed Cont): 41,50-204 1994
Allowed workplace exposures restricted to high doses RTECS®- TLV/BEI,2007

Neurotoxicity

Type of concern: Reference:
One or more animal studies show brain, nervous system, or behavioral effects at high doses RTECS®- Journal of Medicinal Chemistry 1964
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study National Library of Medicine HazMap

Developmental/reproductive toxicity

Type of concern: Reference:
One or more animal studies show reproductive effects at high doses RTECS®- National Technical Information Service 1230

Irritation (skin, eyes, or lungs)

Type of concern: Reference:
One or more animal studies show skin irritation at moderate doses RTECS®- Union Carbide Data Sheet 1970
One or more animal studies show skin irritation at moderate doses RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J 1986
One or more animal studies show skin irritation at high doses RTECS®- Journal of Medicinal Chemistry 1964

Ecotoxicology

Type of concern: Reference:
Not suspected to be an environmental toxin Environment Canada Domestic Substance List

Persistence and bioaccumulation

Type of concern: Reference:
Not suspected to be bioaccumulative Environment Canada Domestic Substance List



Government, industry, academic studies and classifications

government/industry list/academic study appears on list as classification(s)
Association of Occupational and Environmental ClinicsTRICHLOROTRIFLUOROETHANE• o
FDA Everything Added to FoodCHLOROFLUOROCARBON 113• There is no reported use of the substance and there is no toxicology information available in PAFA.
Environment Canada Domestic Substance ListETHANE, 1,1,2-TRICHLORO-1,2,2-TRIFLUORO-•This chemical was deemed a low human health priority and was NOT flagged by CEPA for further attention. The chemical was flagged for suspected persistence.
National Library of Medicine HazMap1,1,2-TRICHLORO-1,2,2-TRIFLUOROETHANE•Restricted - Regulations that have banned or restricted the use of the agent: See CHLOROFLUOROCARBONS;
•Neurotoxin: CNS Solvent Syndrome;
•PEL (OSHA) - Permissible exposure limit (OSHA): 1000 ppm;
•STEL (ACGIH) - Short-term exposure limits (ACGIH): 1250 ppm;
•LC50 - Lethal concentration in 50% of animals tested: 92500 ppm;
•TLV (ACGIH) - Threshold limit value (ACGIH): 1000 ppm;
•IDLH (NIOSH) - Immediately Dangerous to Life or Health: 2000 ppm;
•Odor Threshold High - The lowest concentration at which a substance can be detected or recognized using the sense of smell: 200 ppm;
•Odor Threshold Low - The lowest concentration at which a substance can be detected or recognized using the sense of smell: 0.5 ppm;
•MAK - Maximum Allowable Concentration (Federal Republic of Germany): 500 ppm;
EPA Categorized List of Inert Pesticide Ingredients1,1,2- TRICHLORO-1,2,2-TRIFLUOROETHANE•Pesticide inerts: potentially toxic, testing priority, according to EPA (Environmental Protection Agency)
EPA Toxic Release Inventory PBTs1,1,2TRICHLORO1,2,2TRIFLUOROETHANE•Toxic, U.S. Environmental Protection Agency Toxics Release Inventory programs
Klaassen, C, 1996FREON 113•Cardiovascular or blood toxicity hazards: suspected
RTECS®- TLV/BEI,2006PROPELLANT 113• occupationally related - ACGIH TLV (human TWA)
RTECS®- TLV/BEI,2007PROPELLANT 113• occupationally related - ACGIH TLV (human TWA)
RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J 1986PROPELLANT 113• skin - Primary skin irritant (rabbit )
RTECS®- Journal of Medicinal Chemistry 1964PROPELLANT 113• skin - Hair (rat LD50)
• gastrointestinal - Other changes (rat LD50)
• brain, nervous system, or behavioral effect - Somnolence (general depressed activity) (rat LD50)
RTECS®- MSHA STANDARD-air: 3,267,1971PROPELLANT 113• occupationally related - MSHA STANDARD-air (human TWA)
RTECS®- National Technical Information Service 1230PROPELLANT 113• reproductive - Abortion (rabbit TDLo)
• reproductive - Fetal death (rabbit TDLo)
• reproductive - Other effects (rabbit TDLo)
RTECS®- OSHA PEL (Construc): 29,1926 1994PROPELLANT 113• occupationally related - OSHA PEL (Construc) (human TWA)
RTECS®- OSHA PEL (Fed Cont): 41,50-204 1994PROPELLANT 113• occupationally related - OSHA PEL (Fed Cont) (human TWA)
RTECS®- OSHA PEL (Gen Indu): 29,1910 1994PROPELLANT 113• occupationally related - OSHA PEL (Gen Indu) (human TWA)
RTECS®- OSHA PEL (Shipyard): 29,1915 1993PROPELLANT 113• occupationally related - OSHA PEL (Shipyard) (human TWA)
RTECS®- Union Carbide Data Sheet 1970PROPELLANT 113• skin - Primary skin irritant (rabbit )



references

government/industry list/academic study reference
Association of Occupational and Environmental ClinicsAOEC (Association of Occupational and Environmental Clinics). 2009. AEOC exposures codes and asthmagen designation.
FDA Everything Added to FoodFDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
Environment Canada Domestic Substance ListEC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
National Library of Medicine HazMapNLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
EPA Categorized List of Inert Pesticide IngredientsEPA (U.S. Environmental Protection Agency). 1987 & 2005. Office of Pesticide Programs. Inert (other) Pesticide Ingredients in Pesticide Products - Categorized List of Inert (other) Pesticide Ingredients.
EPA Toxic Release Inventory PBTsEPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
Scorecard.org Toxicity InformationKlaassen, C., M. Amdur and J. Doull (eds.). Casarett and Doull's Toxicology. The Basic Science of Poisons, 5th Ed. Pergamon Press, NY. 1996.
RTECS®- TLV/BEI,2006RTECS®- TLV/BEI,2006
RTECS®- TLV/BEI,2007RTECS®- TLV/BEI,2007
RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J 1986RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 -,137,1986
RTECS®- Journal of Medicinal Chemistry 1964RTECS®- Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- 7,378,1964
RTECS®- MSHA STANDARD-air: 3,267,1971RTECS®- MSHA STANDARD-air: 3,267,1971
RTECS®- National Technical Information Service 1230RTECS®- National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. OTS0571230
RTECS®- OSHA PEL (Construc): 29,1926 1994RTECS®- OSHA PEL (Construc): 29,1926.55,1994
RTECS®- OSHA PEL (Fed Cont): 41,50-204 1994RTECS®- OSHA PEL (Fed Cont): 41,50-204.50,1994
RTECS®- OSHA PEL (Gen Indu): 29,1910 1994RTECS®- OSHA PEL (Gen Indu): 29,1910.1000,1994
RTECS®- OSHA PEL (Shipyard): 29,1915 1993RTECS®- OSHA PEL (Shipyard): 29,1915.1000,1993
RTECS®- Union Carbide Data Sheet 1970RTECS®- Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) 7/10/1970

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