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National Drinking Water Database


National Drinking Water Database - Chemical Contaminants

Tetrahydrofuran


Status: Unregulated - EPA has not established a maximum legal limit in tapwater for this contaminant.

Tetrahydrofuran is an intermediate in chemical manufacturing to produce food storage and packaging materials, rubber, resins and plastics, and is a solvent for dyes and lacquers. [read more]

 
Detected
Found above
health guidelines
Found above
legal limit
States
8
-
-
Water utilities
183
-
-
People Served
831,627
-
-

Health Concerns for Tetrahydrofuran:


Tetrahydrofuran Exposure by State

Water utilities in 8 states have reported detecting Tetrahydrofuran in treated tap water since 2004, according to EWG's analysis of water quality data supplied by state water agencies.

StateWater Suppliers with Tetrahydrofuran contamination
SystemsPopulation
Texas99453,278
Delaware22219,653
Minnesota883,748
New Jersey342,093
New Mexico1722,588
New Hampshire296,741
Virginia43,223
Illinois1303
Total183831,627

The Most Polluted Communities

183 water utilities reported detecting Tetrahydrofuran in tap water since 2004, according to EWG's analysis of water quality data supplied by state water agencies

Ranked by highest average Tetrahydrofuran level

RankSystem Population Served Positive test results of total reported tests Average Level
(Range)
1Plainfield Village Water Dist
Plainfield, NH
2481 of 1320 ppb
(320 ppb)
2Amazon Park
Rochester, NH
1102 of 2315.55 ppb
(0.09 to 631 ppb)
3Lydall Indus Thermal Soltn Inc
NH
721 of 1219 ppb
(219 ppb)
4Epsom Village District
Epsom, NH
7501 of 1113.5 ppb
(113.5 ppb)
5Quail Hollow Mdwua
Tijeras, NM
331 of 180 ppb
(80 ppb)
6Mallard Lakes
Selbyville, DE
9001 of 162.9 ppb
(62.9 ppb)
7Hidden Acres Mobile Home Park
Pelican Rapids, MN
1001 of 153 ppb
(53 ppb)
8Pinewood Acres
Dover, DE
1,2001 of 150.7 ppb
(50.7 ppb)
9Tamworth Pines Coop
Tamworth, NH
1381 of 147 ppb
(47 ppb)
10Warwick Mills Inc
NH
1101 of 140 ppb
(40 ppb)

Testing Summary for Tetrahydrofuran

Are tests routinely required for Tetrahydrofuran by federal law?No
Water suppliers reporting tests for Tetrahydrofuran (2004-2009):4,136 of 47,576
Average testing rate for water supplier reporting tests (2004-2009):0.4 per year

Cancer

Type of concern: Reference:
Limited evidence of carcinogenicity Amer Conf of Gov't Industrial Hygienists - Carcinogens
One or more in vitro tests non-mammalian cells show positive mutation results RTECS®- Gigiena Truda i Professional'nye Zabolevaniya 1982

Organ system toxicity (non-reproductive)

Type of concern: Reference:
Classified as expected to be toxic or harmful Environment Canada Domestic Substance List
Limited evidence of gastrointestinal or liver toxicity National Library of Medicine HazMap

Developmental/reproductive toxicity

Type of concern: Reference:
Limited evidence of developmental toxicity Jankovic, J, 1996

Irritation (skin, eyes, or lungs)

Type of concern: Reference:
Classified as irritant European Union - Classification & Labelling

Occupational hazards

Type of concern: Reference:
Allowed workplace exposures restricted to high doses RTECS®- TLV/BEI,2007
Allowed workplace exposures restricted to high doses RTECS®- MSHA STANDARD-air: 3,252,1971
Allowed workplace exposures restricted to high doses RTECS®- OSHA PEL (Gen Indu): 29,1910 1994
Allowed workplace exposures restricted to high doses RTECS®- OSHA PEL (Construc): 29,1926 1994
Allowed workplace exposures restricted to high doses RTECS®- OSHA PEL (Shipyard): 29,1915 1993
Allowed workplace exposures restricted to high doses RTECS®- OSHA PEL (Fed Cont): 41,50-204 1994

Miscellaneous

Type of concern: Reference:
Occupational hazards related to handling European Union - Classification & Labelling

Neurotoxicity

Type of concern: Reference:
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study National Library of Medicine HazMap



Government, industry, academic studies and classifications

government/industry list/academic study appears on list as classification(s)
European Union - Classification & LabellingTETRAHYDROFURAN•Highly flammable
•Highly flammable
•Irritant (eyes, skin, or lungs)
•Irritating to eyes and respiratory system
Amer Conf of Gov't Industrial Hygienists - CarcinogensTETRAHYDROFURAN•Confirmed animal carcinogen with unknown relevance to humans (ACGIH classification A3)
Association of Occupational and Environmental ClinicsTETRAHYDROFURAN• o
Environment Canada Domestic Substance ListFURAN, TETRAHYDRO-•This chemical was deemed a moderate human health priority and was flagged by CEPA for further attention.
National Library of Medicine HazMapTETRAHYDROFURAN•Skin Designation (ACGIH) - Danger of cutaneous absorption (ACGIH): Yes;
•Hepatotoxin: Hepatotoxin, Primary;
•Neurotoxin: CNS Solvent Syndrome;
•PEL (OSHA) - Permissible exposure limit (OSHA): 200 ppm;
•STEL (ACGIH) - Short-term exposure limits (ACGIH): 100 ppm;
•LC50 - Lethal concentration in 50% of animals tested: 37800 ppm;
•TLV (ACGIH) - Threshold limit value (ACGIH): 50 ppm;
•BEI - Biological Exposure Indices (American Conference of Governmental Industrial Hygiene, ACGIH): Tetrahydrofuran in urine = 8 mg/L; sample at end of shift;;
•Flammability (NFPA) - NFPA flammability code: 0 = will not burn; 1 = must be preheated; 2 = high ambient temp required; 3 = may ignite at ambient temp; 4 = burn readily: 3: may ignite at ambient temperature;
•IDLH (NIOSH) - Immediately Dangerous to Life or Health: 2000 ppm;
•Odor Threshold High - The lowest concentration at which a substance can be detected or recognized using the sense of smell: 61 ppm;
•Odor Threshold Low - The lowest concentration at which a substance can be detected or recognized using the sense of smell: 0.09 ppm;MA: 50
Jankovic, J, 1996TETRAHYDROFURAN•Developmental toxicity hazards: suspected
RTECS®- TLV/BEI,2007TETRAHYDROFURAN• occupationally related - ACGIH TLV (human TWA)
RTECS®- Gigiena Truda i Professional'nye Zabolevaniya 1982TETRAHYDROFURAN• mutagenic - Positive mutation assay: Mutation in Micro-organism (Escherichia coli )
RTECS®- MSHA STANDARD-air: 3,252,1971TETRAHYDROFURAN• occupationally related - MSHA STANDARD-air (human TWA)
RTECS®- OSHA PEL (Construc): 29,1926 1994TETRAHYDROFURAN• occupationally related - OSHA PEL (Construc) (human TWA)
RTECS®- OSHA PEL (Fed Cont): 41,50-204 1994TETRAHYDROFURAN• occupationally related - OSHA PEL (Fed Cont) (human TWA)
RTECS®- OSHA PEL (Gen Indu): 29,1910 1994TETRAHYDROFURAN• occupationally related - OSHA PEL (Gen Indu) (human TWA)
RTECS®- OSHA PEL (Shipyard): 29,1915 1993TETRAHYDROFURAN• occupationally related - OSHA PEL (Shipyard) (human TWA)



references

government/industry list/academic study reference
European Union - Classification & LabellingCPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
Amer Conf of Gov't Industrial Hygienists - CarcinogensACGIH (American Conference of Governmental Industrial Hygienists) 2008. ACGIH cancer classification system. www.acgih.org.
Association of Occupational and Environmental ClinicsAOEC (Association of Occupational and Environmental Clinics). 2009. AEOC exposures codes and asthmagen designation.
Environment Canada Domestic Substance ListEC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
National Library of Medicine HazMapNLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
Scorecard.org Toxicity InformationJankovic, J. A Screening Method for Occupational Reproductive Health Risk. American Industrial Hygiene Association Journal. 57: 641-649. 1996.
RTECS®- TLV/BEI,2007RTECS®- TLV/BEI,2007
RTECS®- Gigiena Truda i Professional'nye Zabolevaniya 1982RTECS®- Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI 26(1),43,1982
RTECS®- MSHA STANDARD-air: 3,252,1971RTECS®- MSHA STANDARD-air: 3,252,1971
RTECS®- OSHA PEL (Construc): 29,1926 1994RTECS®- OSHA PEL (Construc): 29,1926.55,1994
RTECS®- OSHA PEL (Fed Cont): 41,50-204 1994RTECS®- OSHA PEL (Fed Cont): 41,50-204.50,1994
RTECS®- OSHA PEL (Gen Indu): 29,1910 1994RTECS®- OSHA PEL (Gen Indu): 29,1910.1000,1994
RTECS®- OSHA PEL (Shipyard): 29,1915 1993RTECS®- OSHA PEL (Shipyard): 29,1915.1000,1993

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