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National Drinking Water Database


National Drinking Water Database - Chemical Contaminants

Isopropyl alcohol


Status: Unregulated - EPA has not established a maximum legal limit in tapwater for this contaminant.

Isopropyl alcohol is a synthetic chemical used as a solvent for industrial and consumer products, as an intermediate in chemical and pharmaceutical manufacturing and as a gasoline additive.

 
Detected
Found above
health guidelines
Found above
legal limit
States
1
-
-
Water utilities
4
-
-
People Served
49,520
-
-

Health Concerns for Isopropyl alcohol:


Isopropyl alcohol Exposure by State

Water utilities in 1 states have reported detecting Isopropyl alcohol in treated tap water since 2004, according to EWG's analysis of water quality data supplied by state water agencies.

StateWater Suppliers with Isopropyl alcohol contamination
SystemsPopulation
Texas449,520
Total449,520

The Most Polluted Communities

4 water utilities reported detecting Isopropyl alcohol in tap water since 2004, according to EWG's analysis of water quality data supplied by state water agencies

Ranked by highest average Isopropyl alcohol level

RankSystem Population Served Positive test results of total reported tests Average Level
(Range)
1City of Ballinger
Ballinger, TX
6001 of 12.5 ppb
(2.5 ppb)
2EL Paso Water Utilities Public Service Board
El Paso, TX
40,3681 of 11.4 ppb
(1.4 ppb)
3Hudson Wsc
Lufkin, TX
8,3521 of 11.2 ppb
(1.2 ppb)
4North Texas Mwd
Wylie, TX
2001 of 11.2 ppb
(1.2 ppb)

Testing Summary for Isopropyl alcohol

Are tests routinely required for Isopropyl alcohol by federal law?No
Water suppliers reporting tests for Isopropyl alcohol (2004-2007):16 of 47,576
Average testing rate for water supplier reporting tests (2004-2007):1.4 per year

Developmental/reproductive toxicity

Type of concern: Reference:
Limited evidence of developmental toxicity California EPA, Office of Environmental Health Hazard Assessment, 2003
One or more animal studies show reproductive effects at moderate doses RTECS®- Gigiena i Sanitariya 1978
One or more animal studies show reproductive effects at high doses RTECS®- Gigiena i Sanitariya 1978
One or more animal studies show reproductive effects at high doses RTECS®- Regulatory Toxicology and Pharmacology 1996
One or more animal studies show reproductive effects at high doses RTECS®- Toxicologist 1993

Organ system toxicity (non-reproductive)

Type of concern: Reference:
One or more animal studies show sense organ effects at very low doses RTECS®- American Journal of Ophthalmology 1946
Classified as expected to be toxic or harmful Environment Canada Domestic Substance List
Classified as medium human health priority Environment Canada Domestic Substance List
One or more animal studies show sense organ effects at low doses RTECS®- Toxicology and Applied Pharmacology 1980
One or more animal studies show sense organ effects at low doses RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J 1986
Limited evidence of sense organ toxicity California EPA, Office of Environmental Health Hazard Assessment, 2000
Limited evidence of respiratory toxicity California EPA, Office of Environmental Health Hazard Assessment, 2000
Limited evidence of kideny toxicity California EPA, Office of Environmental Health Hazard Assessment, 2003
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient) EPA Toxic Release Inventory PBTs
One or more animal studies show cardiovascular effects at high doses (low dose studies may be unavailable for this ingredient) RTECS®- Journal of Laboratory and Clinical Medicine 1927
One or more animal studies show respiratory effects at high doses (low dose studies may be unavailable for this ingredient) RTECS®- "Toxicology of Drugs and Chemicals," Deichmann, W 1969
One or more animal studies show gastrointestinal effects at high doses (low dose studies may be unavailable for this ingredient) RTECS®- "Toxicology of Drugs and Chemicals," Deichmann, W 1969
One or more animal studies show gastrointestinal effects at high doses (low dose studies may be unavailable for this ingredient) RTECS®- American Journal of Emergency Medicine 1992

Irritation (skin, eyes, or lungs)

Type of concern: Reference:
Classified as irritant European Union - Classification & Labelling
One or more animal studies show skin irritation at moderate doses RTECS®- National Technical Information Service

Cancer

Type of concern: Reference:
One or more in vitro tests on mammalian cells show positive mutation results RTECS®- Gigiena Truda i Professional'nye Zabolevaniya 1981
Cancer - not classifiable/not likely to be human carcinogen Int'l Agency for Research on Cancer (IARC) - Carcinogens

Occupational hazards

Type of concern: Reference:
Allowed workplace exposures restricted to moderate doses European Union - Classification & Labelling
Allowed workplace exposures restricted to high doses RTECS®- TLV/BEI,2006
Allowed workplace exposures restricted to high doses RTECS®- MSHA STANDARD-air: 3,141,1971
Allowed workplace exposures restricted to high doses RTECS®- OSHA PEL (Gen Indu): 29,1910 1994
Allowed workplace exposures restricted to high doses RTECS®- OSHA PEL (Construc): 29,1926 1994
Allowed workplace exposures restricted to high doses RTECS®- OSHA PEL (Shipyard): 29,1915 1993
Allowed workplace exposures restricted to high doses RTECS®- OSHA PEL (Fed Cont): 41,50-204 1994
Allowed workplace exposures restricted to high doses RTECS®- TLV/BEI,2007

Neurotoxicity

Type of concern: Reference:
One or more animal studies show brain, nervous system, or behavioral effect effects at high doses RTECS®- Journal of Laboratory and Clinical Medicine 1927
One or more animal studies show brain, nervous system, or behavioral effect effects at high doses RTECS®- "Toxicology of Drugs and Chemicals," Deichmann, W 1969
One or more animal studies show brain, nervous system, or behavioral effect effects at high doses RTECS®- American Journal of Emergency Medicine 1992
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study National Library of Medicine HazMap

Ecotoxicology

Type of concern: Reference:
Not suspected to be an environmental toxin Environment Canada Domestic Substance List

Miscellaneous

Type of concern: Reference:
Occupational hazards related to handling European Union - Classification & Labelling

Persistence and bioaccumulation

Type of concern: Reference:
Not suspected to be bioaccumulative Environment Canada Domestic Substance List

Multiple, additive exposure sources

Type of concern: Reference:
Designated as safe for general or specific, limited use in food FDA Everything Added to Food



Government, industry, academic studies and classifications

government/industry list/academic study appears on list as classification(s)
European Union - Classification & LabellingPROPAN-2-OL;;ISOPROPYL ALCOHOL;;ISOPROPANOL•Highly flammable
•Highly flammable
•Irritant (eyes, skin, or lungs)
•Irritating to eyes
•Vapours may cause drowsiness and dizziness
Association of Occupational and Environmental ClinicsISOPROPYL ALCOHOL• S
FDA Everything Added to FoodISOPROPYL ALCOHOL• Fully up-to-date toxicology information has been sought.
Environment Canada Domestic Substance List2-PROPANOL•This chemical was deemed a moderate human health priority and was flagged by CEPA for further attention. The chemical was flagged for suspected persistence.
IFRA Fragrance Ingredient ListISOPROPYL ALCOHOL•The chemical has been reported as used in fragrance compounds by IFRA affiliated member companies in 2008.
National Library of Medicine HazMapISOPROPYL ALCOHOL•Neurotoxin: CNS Solvent Syndrome;
•PEL (OSHA) - Permissible exposure limit (OSHA): 400 ppm;
•STEL (ACGIH) - Short-term exposure limits (ACGIH): 400 ppm;
•RD50 - Concentration producing a 50% decrease in respiratory rate in experimental animals following a 10-minute exposure: 17693 ppm;
•LC50 - Lethal concentration in 50% of animals tested: 23040 ppm;
•TLV (ACGIH) - Threshold limit value (ACGIH): 200 ppm;
•Flammability (NFPA) - NFPA flammability code: 0 = will not burn; 1 = must be preheated; 2 = high ambient temp required; 3 = may ignite at ambient temp; 4 = burn readily: 3: may ignite at ambient temperature;
•IDLH (NIOSH) - Immediately Dangerous to Life or Health: 2000 ppm;
•Odor Threshold High - The lowest concentration at which a substance can be detected or recognized using the sense of smell: 610 ppm;
•Odor Threshold Low - The lowest concentration at which a substance can be detected or recognized using the sense of smell: 1 ppm;
•MAK - Maximum Allowable Concentration (Federal Republic of Germany): 200 ppm;
Int'l Agency for Research on Cancer (IARC) - CarcinogensISOPROPANOL•IARC Group 3 (no cancer link)
EPA Toxic Release Inventory PBTs2PROPANOL•Toxic, U.S. Environmental Protection Agency Toxics Release Inventory programs
California EPA, Office of Environmental Health Hazard Assessment, 2000ISOPROPYL ALCOHOL•Skin or sense organ toxicity hazards: suspected
California EPA, Office of Environmental Health Hazard Assessment, 2000ISOPROPYL ALCOHOL•Respiratory toxicity hazards: suspected
California EPA, Office of Environmental Health Hazard Assessment, 2003ISOPROPYL ALCOHOL•Developmental toxicity hazards: suspected
California EPA, Office of Environmental Health Hazard Assessment, 2003ISOPROPYL ALCOHOL•Kidney toxicity hazards: suspected
RTECS®- TLV/BEI,2006ISOPROPYL ALCOHOL• occupationally related - ACGIH TLV (human TWA)
RTECS®- TLV/BEI,2007ISOPROPYL ALCOHOL• occupationally related - ACGIH TLV (human TWA)
RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J 1986ISOPROPYL ALCOHOL• sense organ - Primary eye irritant (rabbit )
RTECS®- "Toxicology of Drugs and Chemicals," Deichmann, W 1969ISOPROPYL ALCOHOL• brain, nervous system, or behavioral effect - Coma ( human LDLo)
• gastrointestinal - Nausea or vomiting ( human LDLo)
• respiratory - Respiratory depression ( human LDLo)
RTECS®- American Journal of Emergency Medicine 1992ISOPROPYL ALCOHOL• brain, nervous system, or behavioral effect - Irritability (infant TDLo)
• gastrointestinal - Nausea or vomiting (infant TDLo)
• brain, nervous system, or behavioral effect - Somnolence (general depressed activity) (infant TDLo)
RTECS®- American Journal of Ophthalmology 1946ISOPROPYL ALCOHOL• sense organ - Primary eye irritant (rabbit )
RTECS®- American Journal of Ophthalmology 1946ISOPROPYL ALCOHOL• sense organ - Primary eye irritant (rabbit )
RTECS®- Gigiena i Sanitariya 1978ISOPROPYL ALCOHOL• reproductive - Fetal death (rat TDLo)
• reproductive - Litter size (rat TDLo)
• reproductive - Menstrual cycle changes or disorders (rat TDLo)
RTECS®- Gigiena Truda i Professional'nye Zabolevaniya 1981ISOPROPYL ALCOHOL• mutagenic - Positive mutation assay: Cytogenetic Analysis (rat ihl)
RTECS®- Gigiena Truda i Professional'nye Zabolevaniya 1981ISOPROPYL ALCOHOL• mutagenic - Positive mutation assay: Cytogenetic Analysis (rat ihl)
RTECS®- Journal of Laboratory and Clinical Medicine 1927ISOPROPYL ALCOHOL• cardiovascular - BP lowering not characterized in autonomic section ( human TDLo)
• brain, nervous system, or behavioral effect - Hallucinations, distorted perceptions ( human TDLo)
• cardiovascular - Pulse rate ( human TDLo)
RTECS®- MSHA STANDARD-air: 3,141,1971ISOPROPYL ALCOHOL• occupationally related - MSHA STANDARD-air (human TWA)
RTECS®- National Technical Information Service ISOPROPYL ALCOHOL• skin - Primary skin irritant (rabbit )
RTECS®- National Technical Information Service ISOPROPYL ALCOHOL• skin - Primary skin irritant (rabbit )
RTECS®- OSHA PEL (Construc): 29,1926 1994ISOPROPYL ALCOHOL• occupationally related - OSHA PEL (Construc) (human TWA)
RTECS®- OSHA PEL (Fed Cont): 41,50-204 1994ISOPROPYL ALCOHOL• occupationally related - OSHA PEL (Fed Cont) (human TWA)
RTECS®- OSHA PEL (Gen Indu): 29,1910 1994ISOPROPYL ALCOHOL• occupationally related - OSHA PEL (Gen Indu) (human TWA)
RTECS®- OSHA PEL (Shipyard): 29,1915 1993ISOPROPYL ALCOHOL• occupationally related - OSHA PEL (Shipyard) (human TWA)
RTECS®- Regulatory Toxicology and Pharmacology 1996ISOPROPYL ALCOHOL• reproductive - Fetotoxicity (rat TDLo)
RTECS®- Toxicologist 1993ISOPROPYL ALCOHOL• reproductive - Mating performance (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 1980ISOPROPYL ALCOHOL• sense organ - Primary eye irritant (rabbit )
RTECS®- Toxicology and Applied Pharmacology 1980ISOPROPYL ALCOHOL• sense organ - Primary eye irritant (rabbit )



references

government/industry list/academic study reference
European Union - Classification & LabellingCPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
Association of Occupational and Environmental ClinicsAOEC (Association of Occupational and Environmental Clinics). 2009. AEOC exposures codes and asthmagen designation.
FDA Everything Added to FoodFDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
Environment Canada Domestic Substance ListEC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
IFRA Fragrance Ingredient ListIFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25
National Library of Medicine HazMapNLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
Int'l Agency for Research on Cancer (IARC) - CarcinogensIARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures).
EPA Toxic Release Inventory PBTsEPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
Scorecard.org Toxicity InformationCalifornia EPA, Office of Environmental Health Hazard Assessment. Acute Reference Exposure Levels (RELs), Averaging Times, and Toxicologic Endpoints. Includes all Acute Reference Exposure Levels (ARELs) developed by OEHHA through May 2000http://www.oehha.org/air/acute_rels/allAcRELs.html
Scorecard.org Toxicity InformationCalifornia EPA, Office of Environmental Health Hazard Assessment. Acute Reference Exposure Levels (RELs), Averaging Times, and Toxicologic Endpoints. Includes all Acute Reference Exposure Levels (ARELs) developed by OEHHA through May 2000http://www.oehha.org/air/acute_rels/allAcRELs.html, National Institute for Occupational Safety and Health's Registry of Toxic Effects of Chemical Substances. See Environmental Defense's Suspect Hazard Identification documentation.
Scorecard.org Toxicity InformationCalifornia EPA, Office of Environmental Health Hazard Assessment. Air Toxics Hot Spots Program Risk Assessment Guidelines, Part III: Technical Support Document 'Determination of Noncancer Chronic Reference Exposure Levels'. Includes all Chronic Reference Exposure Levels (CRELs) adopted by OEHHA as of August 2003 (http://www.oehha.ca.gov/air/chronic_rels/AllChrels.html, plus draft CRELS proposed through March 2004 (http://www.oehha.ca.gov/air/chronic_rels/index.html.
Scorecard.org Toxicity InformationCalifornia EPA, Office of Environmental Health Hazard Assessment. Air Toxics Hot Spots Program Risk Assessment Guidelines, Part III: Technical Support Document 'Determination of Noncancer Chronic Reference Exposure Levels'. Includes all Chronic Reference Exposure Levels (CRELs) adopted by OEHHA as of August 2003 (http://www.oehha.ca.gov/air/chronic_rels/AllChrels.html, plus draft CRELS proposed through March 2004 (http://www.oehha.ca.gov/air/chronic_rels/index.html.
RTECS®- TLV/BEI,2006RTECS®- TLV/BEI,2006
RTECS®- TLV/BEI,2007RTECS®- TLV/BEI,2007
RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J 1986RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 -,191,1986
RTECS®- "Toxicology of Drugs and Chemicals," Deichmann, W 1969RTECS®- "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969 -,339,1969
RTECS®- American Journal of Emergency Medicine 1992RTECS®- American Journal of Emergency Medicine. (WB Saunders, Philadelphia, PA) V.1- 1983- 10,542,1992
RTECS®- American Journal of Ophthalmology 1946RTECS®- American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N. Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 1918- 29,1363,1946
RTECS®- American Journal of Ophthalmology 1946RTECS®- American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N. Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 29,1363,1946
RTECS®- Gigiena i Sanitariya 1978RTECS®- Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- 43(1),8,1978
RTECS®- Gigiena Truda i Professional'nye Zabolevaniya 1981RTECS®- Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI 25(7),33,1981
RTECS®- Gigiena Truda i Professional'nye Zabolevaniya 1981RTECS®- Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI 25(7),33,1981
RTECS®- Journal of Laboratory and Clinical Medicine 1927RTECS®- Journal of Laboratory and Clinical Medicine. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63141) V.1- 1915- 12,326,1927
RTECS®- MSHA STANDARD-air: 3,141,1971RTECS®- MSHA STANDARD-air: 3,141,1971
RTECS®- National Technical Information Service RTECS®- National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. AD-A106-944
RTECS®- National Technical Information Service RTECS®- National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. AD-A106-944
RTECS®- OSHA PEL (Construc): 29,1926 1994RTECS®- OSHA PEL (Construc): 29,1926.55,1994
RTECS®- OSHA PEL (Fed Cont): 41,50-204 1994RTECS®- OSHA PEL (Fed Cont): 41,50-204.50,1994
RTECS®- OSHA PEL (Gen Indu): 29,1910 1994RTECS®- OSHA PEL (Gen Indu): 29,1910.1000,1994
RTECS®- OSHA PEL (Shipyard): 29,1915 1993RTECS®- OSHA PEL (Shipyard): 29,1915.1000,1993
RTECS®- Regulatory Toxicology and Pharmacology 1996RTECS®- Regulatory Toxicology and Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- 23,183,1996
RTECS®- Toxicologist 1993RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 13,75,1993
RTECS®- Toxicology and Applied Pharmacology 1980RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 55,501,1980
RTECS®- Toxicology and Applied Pharmacology 1980RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 55,501,1980

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