National Drinking Water Database
National Drinking Water Database - Chemical Contaminants
Hexachlorobenzene (HCB)
Status: Regulated - EPA has established a maximum legal limit in tapwater for this contaminant.
Hexachlorobenzene is a pollutant from metal refineries and agricultural chemical factories. [read more]
Detected |
Found above health guidelines |
Found above legal limit |
|
|---|---|---|---|
| States | 12 |
12 |
- |
| Water utilities | 21 |
21 |
- |
| People Served | 654,325 |
654,325 |
- |
Health Concerns for Hexachlorobenzene (HCB):
- Cancer
- Endocrine disruption
- Allergies/immunotoxicity
- Developmental/reproductive toxicity
- Neurotoxicity
- Organ system toxicity (non-reproductive)
- Persistence and bioaccumulation
- Occupational hazards
- Biochemical or cellular level changes
- Ecotoxicology
Hexachlorobenzene (HCB) Exposure by State
Water utilities in 12 states have reported detecting Hexachlorobenzene (HCB) in treated tap water since 2004, according to EWG's analysis of water quality data supplied by state water agencies.
| State | Water Suppliers with Hexachlorobenzene (HCB) contamination | Water suppliers reporting Hexachlorobenzene (HCB) above health-based limits | ||
|---|---|---|---|---|
| Systems | Population | Systems | Population | |
| Delaware | 1 | 201,000 | 1 | 201,000 |
| Arizona | 1 | 180,000 | 1 | 180,000 |
| California | 1 | 150,253 | 1 | 150,253 |
| Kentucky | 1 | 34,650 | 1 | 34,650 |
| Arkansas | 1 | 28,775 | 1 | 28,775 |
| Maryland | 2 | 25,184 | 2 | 25,184 |
| Oregon | 2 | 16,580 | 2 | 16,580 |
| Florida | 4 | 11,690 | 4 | 11,690 |
| Connecticut | 4 | 4,250 | 4 | 4,250 |
| Minnesota | 1 | 1,003 | 1 | 1,003 |
| New York | 1 | 800 | 1 | 800 |
| Indiana | 2 | 140 | 2 | 140 |
| Total | 21 | 654,325 | 21 | 654,325 |
The Most Polluted Communities
21 water utilities reported detecting Hexachlorobenzene (HCB) in tap water since 2004, according to EWG's analysis of water quality data supplied by state water agencies
Ranked by highest average Hexachlorobenzene (HCB) level
| Rank | System | Population Served | Positive test results of total reported tests | Average Level (Range) |
|---|---|---|---|---|
| 1 | Scwa, Hillcrest Division (Hlc) Gales Ferry, CT | 699 | 1 of 2 | 0.11 ppb (0 to 0.22 ppb) |
| 2 | Scwa, Gray Farms Division (Grf) Gales Ferry, CT | 460 | 1 of 2 | 0.11 ppb (0 to 0.22 ppb) |
| 3 | Lafayette A-Ok Campground Lafayette, IN | 26 | 2 of 7 | 0.09 ppb (0 to 0.65 ppb) |
| 4 | Scwa, Chesterfield Division (Chf) Gales Ferry, CT | 524 | 1 of 3 | 0.07 ppb (0 to 0.22 ppb) |
| 5 | Scwa Tower-Ferry View Division (Twr-Fvh) Gales Ferry, CT | 2,567 | 1 of 3 | 0.07 ppb (0 to 0.22 ppb) |
| 6 | Edgerton Edgerton, MN | 1,003 | 1 of 3 | 0.03 ppb (0 to 0.1 ppb) |
| 7 | Luke / Newpage Luke Mill Luke, MD | 184 | 1 of 8 | 0.03 ppb (0 to 0.2 ppb) |
| 8 | Sun Mountain Water System Inc Bend, OR | 700 | 1 of 3 | 0.02 ppb (0 to 0.05 ppb) |
| 9 | Bardstown Municipal Water Dept Bardstown, KY | 34,650 | 1 of 7 | 0.02 ppb (0 to 0.11 ppb) |
| 10 | Mcwa, Genesee West Rochester, NY | 800 | 1 of 4 | < 0.01 ppb (0 to 0.04 ppb) |
Health Based Limits for Hexachlorobenzene (HCB)
| Standard | Description | Level |
|---|---|---|
| Maximum Contaminant Limit Goal (MCLG) | A non-enforceable health goal that is set at a level at which no known or anticipated adverse effect on the health of persons occurs and which allows an adequate margin of safety. Source: U.S. Environmental Protection Agency. | 0 ppb |
| EPA Human Health Water Quality Criteria | Water quality criteria set by the US EPA provide guidance for states and tribes authorized to establish water quality standards under the Clean Water Act (CWA) to protect human health. These are non-enforceable standards based upon exposure by both drinking water and the contribution of water contamination to other consumed foods. Source: U.S. Environmental Protection Agency. | <0.01 ppb |
| One in one million (10-6) Cancer Risk | The concentration of a chemical in drinking water corresponding to an excess estimated lifetime cancer risk of 1 in 1,000,000. Source: U.S. Environmental Protection Agency. | 0.02 ppb |
| California Public Health Goals | Defined by the State of California Office of Environmental Health Hazard Assessment (OEHHA) as the level of contaminant that is allowed in drinking water. For acutely toxic substances, levels are set at which scientific evidence indicates that no known or anticipated adverse effects on health will occur, plus an adequate margin-of safety. PHGs for carcinogens or other substances which can cause chronic disease shall be based solely on health effects without regard to cost impacts and shall be set at levels which OEHHA has determined do not pose any significant risk to health. | 0.03 ppb |
| Maximum Contaminant Limit (MCL) | The enforceable standard which defines the highest level of a contaminant that is allowed in drinking water. MCLs are set as close to health-based limits (Maximum Contaminant Level Goals, or MCLGs) as feasible using the best available analytical and treatment technologies and taking cost into consideration. Source: U.S. Environmental Protection Agency. | 1 ppb |
| One in ten thousand (10-4) Cancer Risk | The concentration of a chemical in drinking water corresponding to an excess estimated lifetime cancer risk of 1 in 10,000. Source: U.S. Environmental Protection Agency. | 2 ppb |
| Drinking Water Equivalent Level | A lifetime exposure concentration protective of adverse, noncarcinogenic health effects, that assumes all of the exposure to a contaminant is from drinking water. Source: U.S. Environmental Protection Agency. | 30 ppb |
| Children's health-based limit for 1-day exposure | Concentration of a chemical in drinking water that is not expected to cause any adverse, noncarcinogenic health effects for up to one day of exposure. The One-Day health-based limit (or Health Advisory, HA) is typically set to protect a 10-kg child consuming 1 liter of water per day. Source: U.S. Environmental Protection Agency. | 50 ppb |
| Children's health-based limit for 10-day exposure | Concentration of a chemical in drinking water that is not expected to cause any adverse, noncarcinogenic effects for up to ten days of exposure. The Ten-Day health-based limit (or Health Advisory, HA) is typically set to protect a 10-kg child consuming 1 liter of water per day. Source: U.S. Environmental Protection Agency. | 50 ppb |
Testing Summary for Hexachlorobenzene (HCB)
| Are tests routinely required for Hexachlorobenzene (HCB) by federal law? | Yes |
| Water suppliers reporting tests for Hexachlorobenzene (HCB) (2004-2009): | 19,892 of 47,576 |
| Average testing rate for water supplier reporting tests (2004-2009): | 0.4 per year |
Violation Summary for Hexachlorobenzene (HCB)
Data from the U.S. Environmental Protection Agency includes the following violations of federal standards for Hexachlorobenzene (HCB) since 2004
| Maximum Contaminant Level Exceedance Violations | 0 |
| Monitoring Violations | 1,689 |
| Reporting Violations | 0 |
Cancer
| Type of concern: | Reference: |
| Possible human carcinogen | European Union - Classification & Labelling |
| Possible human carcinogen | EPA Integrated Risk Information System (IRIS) |
| Possible human carcinogen | NTP Report on Carcinogens, 11th Edition |
| Possible human carcinogen | California EPA Proposition 65 |
| Cancer - strong evidence | Proposition 65 List of Carcinogens |
| Limited evidence of carcinogenicity | Amer Conf of Gov't Industrial Hygienists - Carcinogens |
| Limited evidence of carcinogenicity | Int'l Agency for Research on Cancer (IARC) - Carcinogens |
| Cancer - limited evidence | CHE Toxicant and Disease Database |
| One or more in vitro tests on mammalian cells show positive mutation results | RTECS®- Mutation Research 1995 |
| One or more in vitro tests on mammalian cells show positive mutation results | RTECS®- Basic Life Sciences 1986 |
| One or more in vitro tests non-mammalian cells show positive mutation results | RTECS®- Mutation Research 1981 |
| One or more in vitro tests non-mammalian cells show positive mutation results | RTECS®- Rivista di Scienza e Technologia degli Alimenti e di Nutrizione Umana 1976 |
Endocrine disruption
| Type of concern: | Reference: |
| Human disruptor - strong evidence | European Commission on Endocrine Disruption |
| Limited evidence of endocrine disruption | CHE Toxicant and Disease Database |
| Limited evidence of endocrine disruption | BKH/European Commission, 2000 |
| endocrine - weight of evidence unknown/unassessed/unreview: published lit review or major tox study | Illinois EPA Chemicals Associated with Endocrine System |
Allergies/immunotoxicity
| Type of concern: | Reference: |
| Human skin and immune toxicant or allergen - strong evidence | CHE Toxicant and Disease Database |
| Limited evidence of immune system toxicity or allergies | nternational Programme of Chemical Safety Environmental Health Criteria 180, 1996 |
| Limited evidence of immune toxicity or allergies | CHE Toxicant and Disease Database |
Developmental/reproductive toxicity
| Type of concern: | Reference: |
| Human developmental toxicant - strong evidence | Proposition 65 List of Carcinogens |
| Human developmental toxicant - moderate evidence | CHE Toxicant and Disease Database |
| Human reproductive toxicant - moderate evidence | CHE Toxicant and Disease Database |
| Human nervous system toxicant - moderate evidence | Chemicals known to be neurotoxic to humans |
| Limited evidence of developmental toxicity | CHE Toxicant and Disease Database |
| Limited evidence of renal toxicity | CHE Toxicant and Disease Database |
| Limited evidence of reproductive toxicity | Agency for Toxic Substances and Disease Registry, 2004 |
Neurotoxicity
| Type of concern: | Reference: |
| Strong evidence of human neurotoxicity | Chemicals known to be neurotoxic to humans |
Organ system toxicity (non-reproductive)
| Type of concern: | Reference: |
| Known human respiratory toxicant | EPA Hazardous Air Pollutants |
| Known human hematologic toxicant | CHE Toxicant and Disease Database |
| Possible human gastrointestinal toxicant | CHE Toxicant and Disease Database |
| Classified as expected to be toxic or harmful | Environment Canada Domestic Substance List |
| Classified as toxic or harmful | European Union - Classification & Labelling |
| Limited evidence of gastrointestinal or liver toxicity | National Library of Medicine HazMap |
| Limited evidence of sense organ toxicity | US EPA, Air Risk Information Support Center |
| Limited evidence of gastrointestinal or liver toxicity | US EPA, Air Risk Information Support Center, 2003 |
| Limited evidence of cardiovascular or blood toxicity | LaDou, J, 1990 |
| One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient) | National Library of Medicine HazMap |
| Classified as a low human health priority | Environment Canada Domestic Substance List |
Persistence and bioaccumulation
| Type of concern: | Reference: |
| Persistent, bioaccumulative in wildlife and humans | National Library of Medicine HazMap |
| Persistent, bioaccumulative in wildlife and humans | EU PTBs - PRIO database & Secondary PRIO database |
| Persistent, bioaccumulative in wildlife and humans | United Nations Environment Programme/POPs Treaty |
| Persistent, bioaccumulative in wildlife and humans | EPA Toxic Release Inventory PBTs |
| Persistent or bioaccumulative and moderate to high toxicity concern in humans | Environment Canada Domestic Substance List |
| Persistent, bioaccumulative in wildlife | National Library of Medicine HazMap |
| Persistent, bioaccumulative in wildlife | Canada PBTs - Accelerated Reduction/Elimination of Toxics (ARET) |
| Persistent, bioaccumulative in wildlife | Great Lakes BTS (Binational Toxics Strategy) PBTs |
| Persistent, bioaccumulative in wildlife | OSPAR PBTs - Substances of Possible Concern |
| Persistent, bioaccumulative in wildlife | EPA PBTs - Waste Minimization Program (RCRA) |
Occupational hazards
| Type of concern: | Reference: |
| Allowed workplace exposures restricted to very low doses | RTECS®- TLV/BEI,2007 |
| Allowed workplace exposures restricted to low doses | European Union - Classification & Labelling |
Biochemical or cellular level changes
| Type of concern: | Reference: |
| Cancer - limited evidence - immune system | CHE Toxicant and Disease Database |
Ecotoxicology
| Type of concern: | Reference: |
| Wildlife and environmental toxicity | European Union - Classification & Labelling |
| Wildlife and environmental toxicity | EPA Clean Water Act - Priority Pollutants |
| Wildlife and environmental toxicity | Illinois EPA Chemicals Associated with Endocrine System |
| Wildlife and environmental toxicity | European Union - Water Framework Directive |
| Suspected to be an environmental toxin and be persistent or bioaccumulative | Environment Canada Domestic Substance List |
| Suspected to be an environmental toxin | Environment Canada Domestic Substance List |
Government, industry, academic studies and classifications
| government/industry list/academic study | appears on list as | classification(s) |
| European Union - Classification & Labelling | HEXACHLOROBENZENE | •May cause cancer •May cause cancer •Toxic •Toxic: danger of serious damage to health by prolonged exposure if swallowed •Dangerous for the environment •Very toxic to aquatic organisms |
| Amer Conf of Gov't Industrial Hygienists - Carcinogens | HEXACHLOROBENZENE | •Confirmed animal carcinogen with unknown relevance to humans (ACGIH classification A3) |
| Association of Occupational and Environmental Clinics | HEXACHLOROBENZENE | • P |
| Association of Occupational and Environmental Clinics | HEXACHLOROBENZENE | • P |
| EPA Clean Water Act - Priority Pollutants | HEXACHLOROBENZENE | •Priority water pollutant under the Clean Water Act |
| Environment Canada Domestic Substance List | BENZENE, HEXACHLORO- | •This chemical was flagged for further attention by CEPA due to suspected bioaccumulation and aquatic toxicity. The chemical was also flagged as a low human health priority. |
| Illinois EPA Chemicals Associated with Endocrine System | HEXACHLOROBENZENE | •EPA: probable endocrine disruptor |
| EPA Integrated Risk Information System (IRIS) | HEXACHLOROBENZENE | •Group B2: Probable human carcinogen - sufficient data in animals (EPA classification) |
| European Commission on Endocrine Disruption | HEXACHLOROBENZENE (HCB) | HH-CAT1;WF-CAT3 |
| European Union - Banned or Restricted in Cosmetics | HEXACHLOROBENZENE | •Prohibited in EU cosmetics: must not form part of the composition of cosmetic products |
| European Union - Water Framework Directive | HEXACHLOROBENZENE | •Priority substance in EU water policy |
| EPA Hazardous Air Pollutants | HEXACHLOROBENZENE | •Hazardous air pollutant under Clean Air Act |
| National Library of Medicine HazMap | HEXACHLOROBENZENE | •Skin Designation (ACGIH) - Danger of cutaneous absorption (ACGIH): Yes; •Restricted - Regulations that have banned or restricted the use of the agent: Banned from use as a pesticide in the U.S. [EXTOXNET]; •Hepatotoxin: Hepatotoxin, Secondary; •Bioaccumulates: Yes; •Other Poison: Organochlorine Pesticide; •IARC Carcinogen - International Agency for Research on Cancer; classifies chemicals as established (1), probable (2a), or possible (2b) human carcinogens: Possible Carcinogen; •TLV (ACGIH) - Threshold limit value (ACGIH): 0.002 mg/m3; |
| Int'l Agency for Research on Cancer (IARC) - Carcinogens | HEXACHLOROBENZENE | •IARC Group 2B: possible human carcinogen (International Agency for Research on Carcinogens) |
| NTP Report on Carcinogens, 11th Edition | HEXACHLOROBENZENE | •Reasonably anticipated to be a human carcinogen (National Toxicology Program classification) |
| Aarhus Protocol on Persistent Organic Pollutants | HEXACHLORO-BENZENE | Restricted use under the Aahrus Protocol for Persistent Organic Pollutants |
| Aarhus Protocol on Persistent Organic Pollutants | HEXACHLORO-BENZENE | Scheduled for elimination under Aahrus Protocol for Persistent Organic Pollutants |
| Canada PBTs - Accelerated Reduction/Elimination of Toxics (ARET) | HEXACHLORO-BENZENE | •Persistent, bioaccumulative toxicant under Canada's Accelerated Reduction/Elimination of Toxics program - targeted for elimination or reduction |
| EU PTBs - PRIO database & Secondary PRIO database | HEXACHLOROBENZENE | •Persistent, bioaccumulative toxicant - European Chemicals Bureau PBT working group |
| Great Lakes BTS (Binational Toxics Strategy) PBTs | HEXACHLORO-BENZENE | •Persistent, bioaccumulative toxicant - Great Lakes Binational Strategy, Tier 1 concern (highest), targeted for phase-out |
| OSPAR PBTs - Substances of Possible Concern | HEXACHLORO-BENZENE | •Persistent, bioaccumulative toxicant - Oslo-Paris (OSPAR) Convention for the Protection of the Marine Environment of the North-East Atlantic, chemical of concern |
| EPA PBTs - Waste Minimization Program (RCRA) | HEXACHLOROBENZENE | •Persistent, bioaccumulative toxicant - Resource Conservation and Recovery Act, priority chemical for voluntary waste/emission reductions |
| United Nations Environment Programme/POPs Treaty | HEXACHLORO-BENZENE | •Persistent, bioaccumulative toxicant - targeted for emission reductions and process controls under international treaty (Stockholm Convention on Persistent Organic Pollutants, or POPs Convention) |
| United Nations Environment Programme/POPs Treaty | HEXACHLORO-BENZENE | •Persistent, bioaccumulative toxicant - targeted for restrictions under international treaty (Stockholm Convention on Persistent Organic Pollutants, or POPs Convention) |
| EPA Toxic Release Inventory PBTs | HEXACHLORO-BENZENE | •Very persistent and bioaccumulative toxicant - targeted for waste reporting under U.S. Environmental Protection Agency Toxics Release Inventory programs |
| California EPA Proposition 65 | HEXACHLOROBENZENE | •Carcinogen: California Proposition 65 |
| Agency for Toxic Substances and Disease Registry, 2004 | HEXACHLOROBENZENE | •Reproductive toxicity hazards: suspected |
| BKH/European Commission, 2000 | HEXACHLOROBENZENE | •Endocrine toxicity hazards: suspected |
| US EPA, Air Risk Information Support Center | HEXACHLOROBENZENE | •Skin or sense organ toxicity hazards: suspected |
| US EPA, Air Risk Information Support Center, 2003 | HEXACHLOROBENZENE | •Gastrointestinal or liver toxicity hazards: suspected |
| nternational Programme of Chemical Safety Environmental Health Criteria 180, 1996 | HEXACHLOROBENZENE | •Immunotoxicity hazards: suspected |
| LaDou, J, 1990 | HEXACHLOROBENZENE | •Cardiovascular or blood toxicity hazards: suspected |
| Proposition 65 List of Carcinogens | HEXACHLOROBENZENE | •Developmental toxicity hazards: recognized |
| Proposition 65 List of Carcinogens | HEXACHLOROBENZENE | •Cancer hazards: recognized |
| RTECS®- TLV/BEI,2007 | HEXACHLOROBENZENE | • occupationally related - ACGIH TLV (human TWA) |
| RTECS®- Basic Life Sciences 1986 | HEXACHLOROBENZENE | • mutagenic - Positive mutation assay: Mutation in Mammalian Somatic Cells (hamster lng) |
| RTECS®- Mutation Research 1995 | HEXACHLOROBENZENE | • mutagenic - Positive mutation assay: other mutation test systems (mouse orl) |
| RTECS®- Mutation Research 1981 | HEXACHLOROBENZENE | • mutagenic - Positive mutation assay: DNA Adduct (Escherichia coli ) |
| RTECS®- Rivista di Scienza e Technologia degli Alimenti e di Nutrizione Umana 1976 | HEXACHLOROBENZENE | • mutagenic - Positive mutation assay: Mutation in Micro-organism (Saccharomyces cerevisiae ) |
references
| government/industry list/academic study | reference |
| European Union - Classification & Labelling | CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP. |
| Amer Conf of Gov't Industrial Hygienists - Carcinogens | ACGIH (American Conference of Governmental Industrial Hygienists) 2008. ACGIH cancer classification system. www.acgih.org. |
| Association of Occupational and Environmental Clinics | AOEC (Association of Occupational and Environmental Clinics). 2009. AEOC exposures codes and asthmagen designation. |
| EPA Clean Water Act - Priority Pollutants | |
| Environment Canada Domestic Substance List | EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry. |
| Illinois EPA Chemicals Associated with Endocrine System | Illinois EPA (Illinois Environmental Protection Agency). 2000. Preliminary list of chemicals associated with endocrine system effects in animals and humans (*) or in vitro (+). In EPA (U.S. Environmental Protection Agency) 2000. Handbook for Non-Cancer Health Effects Valuation, Appendix C. |
| EPA Integrated Risk Information System (IRIS) | EPA (U.S. Environmental Protection Agency). 2008. Integrated Risk Information System (IRIS). Evidence for human carcinogenicity based on 1986-2005 guidelines. |
| European Commission on Endocrine Disruption | EU (European Union)- Strategy for Endocrine Disrupters 2007. Commision on endocrin disruption requested by the European Parliament in 1998. |
| European Union - Banned or Restricted in Cosmetics | EC (European Commission of the European Union). 1999-2006. Enterprise Directorate-General Pharmaceuticals and Cosmetics. The rules governing cosmetic products in the European Union, Volume 1, "Cosmetics legislation." |
| European Union - Water Framework Directive | EU (European Union). 2000. Water Framework Directive (Directive 2000/60/EC ) - integrated river basin management for Europe. List of priority substances. |
| EPA Hazardous Air Pollutants | EPA (U.S. Environmental Protection Agency). 2005. Office of Air. The 112(b)1 Hazardous Air Pollutants List (as modified). Last modified: 12 Dec 2005. |
| National Library of Medicine HazMap | NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents. |
| Int'l Agency for Research on Cancer (IARC) - Carcinogens | IARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures). |
| NTP Report on Carcinogens, 11th Edition | NTP (National Toxicology Program). 2005. Report on Carcinogens, Eleventh Edition; U.S. Department of Health and Human Services, Public Health Service, National Toxicology Program. |
| Aarhus Protocol on Persistent Organic Pollutants | Aarhus LRTAP. 1998. Aarhus Protocol on Persistent Organic Pollutants (POPs). Geneva Convention on Long-range Transboundary Air Pollution, United Nations Environment Program. |
| Canada PBTs - Accelerated Reduction/Elimination of Toxics (ARET) | EC (Environment Canada). 1994. Accelerated Reduction/Elimination of Toxics (ARET). ARET substance list of persistent, bioaccumulative and toxic chemicals. |
| EU PTBs - PRIO database & Secondary PRIO database | EU (European Union). 2006. Persistent, bioaccumulative chemicals identified in PRIO database - a tool for risk reduction of chemicals. Secondary PRIO database - a tool for risk reduction of chemicals. Secondary Kemi. Place Published, Kemi-Swedish Chemicals Inspectorate. |
| Great Lakes BTS (Binational Toxics Strategy) PBTs | Great Lakes BTS (Binational Toxics Strategy). 1997. Canada-United States Strategy for the Virtual Elimination of Persistent Toxic Substances in the Great Lakes. Appendix I - Level 1 and Level 2 substances. |
| OSPAR PBTs - Substances of Possible Concern | OSPAR (Oslo-Paris). 2002. OSPAR List of Substances of Possible Concern. Secondary OSPAR List of Substances of Possible Concern. Secondary OSPAR. Place Published, OSPAR Convention for the Protection of the Marine Environement of North-East Atlanic. |
| EPA PBTs - Waste Minimization Program (RCRA) | EPA (U.S. Environmental Protection Agency). 1998. Resource Conservatin and Recovery Act (RCRA) Waste Minimization Program - priority chemicals for elimination or reduction. |
| United Nations Environment Programme/POPs Treaty | UNEP (United Nations Environment Programme). 2001. Stockholm Convention on Persistent Organic Pollutants (POPs) — POPs Treaty. |
| EPA Toxic Release Inventory PBTs | EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule. |
| California EPA Proposition 65 | California EPA (California Environmental Protection Agency). 9/2008. Office of Environmental Health Hazard Assessment. Safe Drinking Water and Toxic Enforcement Act of 1986. Chemicals known to the State to cause cancer or reproductive toxicity. |
| Scorecard.org Toxicity Information | Agency for Toxic Substances and Disease Registry. Minimal risk Levels for Hazardous Substances. January 2004. http://www.atsdr.cdc.gov/mrls.html, US EPA. Roadmaps to Sources of Information on Chemicals Listed in the Emergency Planning Community and Community Right-to-Know Act (Also Known as SARA Title 3), Section 313 Toxic Release Inventory (for Microcomputers). (Report Number EPADFDK92040). 1991. Data file distributed in 2 diskettes by Office of Pollution, Prevention, and Toxics, Environmental Protection Agency, Washington, DC. NOTE: Datasource no longer being maintained by EPA; not currently available online., Frazier , L. and M. L. Hage (eds.). Reproductive Hazards of the Workplace, Wiley Europe, 1998. Table 10 (Partial List of Reproductive Toxicants) available at http://www.pharmacy.ohio-state.edu/homepage/safety/chemhygiene_table_repro.pdf. |
| Scorecard.org Toxicity Information | BKH/European Commission. Towards the establishment of a priority list of substances for further evaluation of their role in endocrine disruption: - preparation of a candidate list of substances as a basis for priority setting. Final report-November 2000. http://europa.eu.int/comm/environment/docum/01262_en.htm#bkh. Category 1 chemicals from Annex 1: Candidate list of 553 substances. http://europa.eu.int/comm/environment/docum/bkh_annex_01.pdf, Brucker-Davis, F. Effects of Environmental Synthetic Chemicals on Thyroid Function. Thyroid. 8(9): 827-856. 1998., Illinois EPA. Endocrine Disruptors Strategy. 1997. (Table 1: Preliminary List of Chemicals Associated with Endocrine System Effects in Animals and Humans or In Vitro). http://www.nihs.go.jp/hse/environ/illiepatable.htm, Japanese National Institute of Health Sciences. Lists of Paradigmatic Chemicals. http://www.nihs.go.jp/hse/endocrine-e/paradigm/paradigm.html, Keith, L.H. (ed.). Environmental Endocrine Disruptors. John Wiley & Sons, NY. 1997. http://www.wileyeurope.com/cda/product/0,,0471191450%7Cdesc%7C3037,00.html, National Institute for Occupational Safety and Health's Registry of Toxic Effects of Chemical Substances. See Environmental Defense's Suspect Hazard Identification documentation. |
| Scorecard.org Toxicity Information | US EPA, Air Risk Information Support Center. Health Effects Notebook for Hazardous Air Pollutants. http://www.epa.gov/ttnatw01/hlthef/hapindex.html |
| Scorecard.org Toxicity Information | US EPA, Air Risk Information Support Center. Health Effects Notebook for Hazardous Air Pollutants. http://www.epa.gov/ttnatw01/hlthef/hapindex.html, California EPA, Office of Environmental Health Hazard Assessment. Air Toxics Hot Spots Program Risk Assessment Guidelines, Part III: Technical Support Document 'Determination of Noncancer Chronic Reference Exposure Levels'. Includes all Chronic Reference Exposure Levels (CRELs) adopted by OEHHA as of August 2003 (http://www.oehha.ca.gov/air/chronic_rels/AllChrels.html, plus draft CRELS proposed through March 2004 (http://www.oehha.ca.gov/air/chronic_rels/index.html., National Institute for Occupational Safety and Health's Registry of Toxic Effects of Chemical Substances. See Environmental Defense's Suspect Hazard Identification documentation., Zimmerman, H.J. and J.H. Lewis. Chemical- and Toxin-Induced Hepatotoxicity. Gastroenterology Clinics of North America. 24(4): 1027-1045. 1995. (Table 3: Forms of environmental hepatic injury). |
| Scorecard.org Toxicity Information | nternational Programme of Chemical Safety Environmental Health Criteria 180. Principles and Methods for Assessing Direct Immunotoxicity Associated with Exposure to Chemicals. World Health Organization. Geneva, 1996. (Table 1: Examples of compounds that are immunotoxic for humans or rodents). |
| Scorecard.org Toxicity Information | LaDou, J. (ed.). Occupational Medicine. Appleton & Lange, Norwalk, CN. 1990., National Institute for Occupational Safety and Health's Registry of Toxic Effects of Chemical Substances. See Environmental Defense's Suspect Hazard Identification documentation. |
| Scorecard.org Toxicity Information | Proposition 65 List of Carcinogens (July 2004) can be obtained from http://www.oehha.ca.gov/prop65/prop65_list/Newlist.html. |
| Scorecard.org Toxicity Information | Proposition 65 List of Carcinogens (July 2004) can be obtained from http://www.oehha.ca.gov/prop65/prop65_list/Newlist.html. |
| RTECS®- TLV/BEI,2007 | RTECS®- TLV/BEI,2007 |
| RTECS®- Basic Life Sciences 1986 | RTECS®- Basic Life Sciences. (Plenum Pub. Corp., 223 Spring St., New York, NY 10003) V.1- 39,359,1986 |
| RTECS®- Mutation Research 1995 | RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 343,157,1995 |
| RTECS®- Mutation Research 1981 | RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 89,95,1981 |
| RTECS®- Rivista di Scienza e Technologia degli Alimenti e di Nutrizione Umana 1976 | RTECS®- Rivista di Scienza e Technologia degli Alimenti e di Nutrizione Umana. Review of Science and Technology of Food and Human Nutrition. (Bologna, Italy) V.5-6, 1975-76. Discontinued. 6,161,1976 |
"RTECS®" is a United States trademark owned and licensed under authority of the U.S. Government, by and through MDL Information Systems, Inc.
