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National Drinking Water Database


National Drinking Water Database - Chemical Contaminants

Dinoseb


Status: Regulated - EPA has established a maximum legal limit in tapwater for this contaminant.

Dinoseb is an herbicide historically used on soybeans and vegetables; it is associated with birth defects and reproductive difficulties and has been banned in the U.S. since 1986. [read more]

 
Detected
Found above
health guidelines
Found above
legal limit
States
14
-
-
Water utilities
33
-
-
People Served
443,566
-
-

Health Concerns for Dinoseb:


Dinoseb Exposure by State

Water utilities in 14 states have reported detecting Dinoseb in treated tap water since 2004, according to EWG's analysis of water quality data supplied by state water agencies.

StateWater Suppliers with Dinoseb contamination
SystemsPopulation
Delaware3240,930
Arizona186,000
Massachusetts246,600
Wisconsin420,992
California217,738
Maryland614,252
Florida19,445
New Mexico54,238
North Carolina31,897
New York2851
Indiana1378
New Hampshire193
Nebraska192
Washington160
Total33443,566

The Most Polluted Communities

33 water utilities reported detecting Dinoseb in tap water since 2004, according to EWG's analysis of water quality data supplied by state water agencies

Ranked by highest average Dinoseb level

RankSystem Population Served Positive test results of total reported tests Average Level
(Range)
1Clearview Utilities Corp.
Kearney, NE
921 of 12.1 ppb
(2.1 ppb)
2Arden Farms, Inc.
Arden, NY
511 of 11.7 ppb
(1.7 ppb)
3Arrow Springs
Raleigh, NC
801 of 60.9 ppb
(0 to 5.4 ppb)
4Kontree Apartments Water System
Ferndale, WA
601 of 10.66 ppb
(0.66 ppb)
5Jefferson Landing
Jefferson, NC
4006 of 100.53 ppb
(0 to 2.59 ppb)
6Country Hills of East Kingston
NH
931 of 40.5 ppb
(0 to 2 ppb)
7City of Mcfarland
Mcfarland, CA
12,1381 of 20.5 ppb
(0 to 1 ppb)
8Rehoboth Beach Water Department
Rehoboth, DE
29,7873 of 70.35 ppb
(0 to 1.15 ppb)
9Mesilla Park Manor Water System
Las Cruces, NM
8481 of 20.28 ppb
(0 to 0.56 ppb)
10Valle Del Rio Water System
Santa Teresa, NM
2431 of 20.26 ppb
(0 to 0.52 ppb)

Health Based Limits for Dinoseb

StandardDescriptionLevel
Maximum Contaminant Limit (MCL)The enforceable standard which defines the highest level of a contaminant that is allowed in drinking water. MCLs are set as close to health-based limits (Maximum Contaminant Level Goals, or MCLGs) as feasible using the best available analytical and treatment technologies and taking cost into consideration. Source: U.S. Environmental Protection Agency.7 ppb
Maximum Contaminant Limit Goal (MCLG)A non-enforceable health goal that is set at a level at which no known or anticipated adverse effect on the health of persons occurs and which allows an adequate margin of safety. Source: U.S. Environmental Protection Agency.7 ppb
Lifetime health-based limit, non-cancer riskConcentration of a chemical in drinking water that is not expected to cause any adverse, noncarcinogenic health effects for a lifetime of exposure. The Lifetime health-based limit (or Health Advisory, HA) is based on exposure for a a 70-kg adult consuming 2 liters of water per day. Source: U.S. Environmental Protection Agency.7 ppb
California Public Health GoalsDefined by the State of California Office of Environmental Health Hazard Assessment (OEHHA) as the level of contaminant that is allowed in drinking water. For acutely toxic substances, levels are set at which scientific evidence indicates that no known or anticipated adverse effects on health will occur, plus an adequate margin-of safety. PHGs for carcinogens or other substances which can cause chronic disease shall be based solely on health effects without regard to cost impacts and shall be set at levels which OEHHA has determined do not pose any significant risk to health.14 ppb
Drinking Water Equivalent LevelA lifetime exposure concentration protective of adverse, noncarcinogenic health effects, that assumes all of the exposure to a contaminant is from drinking water. Source: U.S. Environmental Protection Agency.35 ppb
Children's health-based limit for 1-day exposureConcentration of a chemical in drinking water that is not expected to cause any adverse, noncarcinogenic health effects for up to one day of exposure. The One-Day health-based limit (or Health Advisory, HA) is typically set to protect a 10-kg child consuming 1 liter of water per day. Source: U.S. Environmental Protection Agency.300 ppb
Children's health-based limit for 10-day exposureConcentration of a chemical in drinking water that is not expected to cause any adverse, noncarcinogenic effects for up to ten days of exposure. The Ten-Day health-based limit (or Health Advisory, HA) is typically set to protect a 10-kg child consuming 1 liter of water per day. Source: U.S. Environmental Protection Agency.300 ppb

Testing Summary for Dinoseb

Are tests routinely required for Dinoseb by federal law?Yes
Water suppliers reporting tests for Dinoseb (2004-2009):19,798 of 47,576
Average testing rate for water supplier reporting tests (2004-2009):0.4 per year

Violation Summary for Dinoseb

Data from the U.S. Environmental Protection Agency includes the following violations of federal standards for Dinoseb since 2004

Maximum Contaminant Level Exceedance Violations0
Monitoring Violations1,670
Reporting Violations0

Neurotoxicity

Type of concern: Reference:
Strong evidence of human neurotoxicity Chemicals known to be neurotoxic to humans

Developmental/reproductive toxicity

Type of concern: Reference:
Possible human developmental toxicant California EPA Proposition 65
Human developmental toxicant - strong evidence Proposition 65 List of Carcinogens
Human reproductive toxicant - strong evidence Proposition 65 List of Carcinogens
Limited evidence of reproductive toxicity European Union - Classification & Labelling
Human nervous system toxicant - moderate evidence Chemicals known to be neurotoxic to humans
Possible human reproductive or developmental toxin Environment Canada Domestic Substance List
Limited evidence of developmental toxicity CHE Toxicant and Disease Database

Organ system toxicity (non-reproductive)

Type of concern: Reference:
Classified as a high human health priority Environment Canada Domestic Substance List
One or more animal studies show sense organ effects at very low doses RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J 1986
Classified as toxic or harmful European Union - Classification & Labelling
Limited evidence of gastrointestinal or liver toxicity National Library of Medicine HazMap
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient) National Library of Medicine HazMap
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient) EPA Toxic Release Inventory PBTs
Classified as not expected to be potentially toxic or harmful Environment Canada Domestic Substance List

Occupational hazards

Type of concern: Reference:
Allowed workplace exposures restricted to low doses European Union - Classification & Labelling

Endocrine disruption

Type of concern: Reference:
Limited evidence of endocrine disruption Japanese National Institute of Health Sciences

Cancer

Type of concern: Reference:
Cancer - limited evidence US EPA, Office of Pesticide Programs, 2002
Cancer - not classifiable/not likely to be human carcinogen EPA Integrated Risk Information System (IRIS)
One or more in vitro tests non-mammalian cells show positive mutation results RTECS®- Mutation Research 1973

Irritation (skin, eyes, or lungs)

Type of concern: Reference:
Classified as irritant European Union - Classification & Labelling

Ecotoxicology

Type of concern: Reference:
Wildlife and environmental toxicity European Union - Classification & Labelling
Suspected to be an environmental toxin Environment Canada Domestic Substance List

Persistence and bioaccumulation

Type of concern: Reference:
Not suspected to be persistent Environment Canada Domestic Substance List
Not suspected to be bioaccumulative Environment Canada Domestic Substance List

Miscellaneous

Type of concern: Reference:
Occupational hazards related to handling European Union - Classification & Labelling



Government, industry, academic studies and classifications

government/industry list/academic study appears on list as classification(s)
European Union - Classification & LabellingDINOSEB•Risk of explosion if heated under confinement
•Toxic
•Toxic in contact with skin and ingestion
•May be toxic to the reproductive system
•May cause harm to the unborn child
•Limited evidence of reproductive toxicity
•Possible risk of impaired fertility
•Irritant (eyes, skin, or lungs)
•Irritating to eyes
•Dangerous for the environment
•Very toxic to aquatic organisms
Environment Canada Domestic Substance ListPHENOL, 2-(1-METHYLPROPYL)-4,6-DINITRO-•This chemical was deemed a high human health priority even though it did not meet the strict criteria of the categorization exercise of CEPA. The chemical was flagged for suspected aquatic toxicity, developmental, and reproductive concerns.
EPA Integrated Risk Information System (IRIS)DINOSEB•Group D: Not classifiable as to human carcinogenicity (EPA classification)
European Commission on Endocrine DisruptionDINOSEBHH-CAT3b;WF-CAT3b
European Union - Banned or Restricted in CosmeticsDINOSEB, ITS SALTS AND ESTERS•Restricted in EU cosmetics (mandatory manufacturing or structural specifications)
National Library of Medicine HazMap4,6-DINITRO-O-SEC-BUTYL PHENOL•Restricted - Regulations that have banned or restricted the use of the agent: All uses cancelled in the U.S. in 1986; [EXTOXNET];
•Hepatotoxin: Hepatotoxin, Secondary;
•Nephrotoxin: Yes;
•Other Poison: Uncoupler;
EPA Toxic Release Inventory PBTs2(1METHYLPROPYL)4,6DINITROPHENOL•Toxic, U.S. Environmental Protection Agency Toxics Release Inventory programs
California EPA Proposition 65DINOSEB•Developmental toxin: California Proposition 65
Japanese National Institute of Health SciencesDINITROBUTYL PHENOL•Endocrine toxicity hazards: suspected
US EPA, Office of Pesticide Programs, 2002DINITROBUTYL PHENOL•Cancer hazards: suspected
Proposition 65 List of CarcinogensDINITROBUTYL PHENOL•Developmental toxicity hazards: recognized
Proposition 65 List of CarcinogensDINITROBUTYL PHENOL•Reproductive toxicity hazards: recognized
RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J 1986DINOSEB• sense organ - Primary eye irritant (rabbit )
RTECS®- Mutation Research 1973DINOSEB• mutagenic - Positive mutation assay: Gene Conversion and Mitotic Recombination (Saccharomyces cerevisiae )



references

government/industry list/academic study reference
European Union - Classification & LabellingCPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
Environment Canada Domestic Substance ListEC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
EPA Integrated Risk Information System (IRIS)EPA (U.S. Environmental Protection Agency). 2008. Integrated Risk Information System (IRIS). Evidence for human carcinogenicity based on 1986-2005 guidelines.
European Commission on Endocrine DisruptionEU (European Union)- Strategy for Endocrine Disrupters 2007. Commision on endocrin disruption requested by the European Parliament in 1998.
European Union - Banned or Restricted in CosmeticsEC (European Commission of the European Union). 1999-2006. Enterprise Directorate-General Pharmaceuticals and Cosmetics. The rules governing cosmetic products in the European Union, Volume 1, "Cosmetics legislation."
National Library of Medicine HazMapNLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
EPA Toxic Release Inventory PBTsEPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
California EPA Proposition 65California EPA (California Environmental Protection Agency). 9/2008. Office of Environmental Health Hazard Assessment. Safe Drinking Water and Toxic Enforcement Act of 1986. Chemicals known to the State to cause cancer or reproductive toxicity.
Scorecard.org Toxicity InformationJapanese National Institute of Health Sciences. Lists of Paradigmatic Chemicals. http://www.nihs.go.jp/hse/endocrine-e/paradigm/paradigm.html
Scorecard.org Toxicity InformationUS EPA, Office of Pesticide Programs. List of Chemicals Evaluated for Carcinogenic Potential (5/10/2002). OPP, Washington, DC. http://www.epi.uci.edu/valleycenter/EPAListCarcinogenicChemicals.pdf
Scorecard.org Toxicity InformationProposition 65 List of Carcinogens (July 2004) can be obtained from http://www.oehha.ca.gov/prop65/prop65_list/Newlist.html.
Scorecard.org Toxicity InformationProposition 65 List of Carcinogens (July 2004) can be obtained from http://www.oehha.ca.gov/prop65/prop65_list/Newlist.html.
RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J 1986RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 -,679,1986
RTECS®- Mutation Research 1973RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 21,83,1973

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