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National Drinking Water Database


National Drinking Water Database - Chemical Contaminants

Dimethylphthalate


Status: Unregulated - EPA has not established a maximum legal limit in tapwater for this contaminant.

Dimethylphthalate is a manufactured chemicals used in solid rocket propellants, plastics, molding powders, pesticides and insect repellants. [read more]

 
Detected
Found above
health guidelines
Found above
legal limit
States
3
-
-
Water utilities
3
-
-
People Served
612,500
-
-

Health Concerns for Dimethylphthalate:


Dimethylphthalate Exposure by State

Water utilities in 3 states have reported detecting Dimethylphthalate in treated tap water since 2004, according to EWG's analysis of water quality data supplied by state water agencies.

StateWater Suppliers with Dimethylphthalate contamination
SystemsPopulation
Washington1211,500
Delaware1201,000
California1200,000
Total3612,500

The Most Polluted Communities

3 water utilities reported detecting Dimethylphthalate in tap water since 2004, according to EWG's analysis of water quality data supplied by state water agencies

Ranked by highest average Dimethylphthalate level

RankSystem Population Served Positive test results of total reported tests Average Level
(Range)
1Glendale-City, Water Dept.
Glendale, CA
200,0001 of 380.23 ppb
(0 to 8.8 ppb)
2City of Spokane
Spokane, WA
211,5001 of 60.04 ppb
(0 to 0.23 ppb)
3Artesian Water Company
Newark, DE
201,0001 of 73< 0.01 ppb
(0 to 0.1 ppb)

Health Based Limits for Dimethylphthalate

StandardDescriptionLevel
EPA Human Health Water Quality CriteriaWater quality criteria set by the US EPA provide guidance for states and tribes authorized to establish water quality standards under the Clean Water Act (CWA) to protect human health. These are non-enforceable standards based upon exposure by both drinking water and the contribution of water contamination to other consumed foods. Source: U.S. Environmental Protection Agency.270000 ppb

Testing Summary for Dimethylphthalate

Are tests routinely required for Dimethylphthalate by federal law?No
Water suppliers reporting tests for Dimethylphthalate (2004-2009):2,553 of 47,576
Average testing rate for water supplier reporting tests (2004-2009):0.4 per year

Allergies/immunotoxicity

Type of concern: Reference:
Known human immune system toxicant or allergen National Library of Medicine HazMap

Organ system toxicity (non-reproductive)

Type of concern: Reference:
Known human respiratory toxicant EPA Hazardous Air Pollutants
Classified as medium human health priority Environment Canada Domestic Substance List
One or more animal studies show blood effects at very low doses RTECS®- Gigiena i Sanitariya 1974
One or more animal studies show kidney or renal system effects at very low doses RTECS®- Gigiena i Sanitariya 1974
One or more animal studies show liver effects at very low doses RTECS®- Gigiena i Sanitariya 1974
Limited evidence of respiratory toxicity US EPA, Air Risk Information Support Center
One or more animal studies show effects at moderate doses (low dose studies may be unavailable for this ingredient) EPA Categorized List of Inert Pesticide Ingredients
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient) EPA Toxic Release Inventory PBTs
One or more animal studies show sense organ effects at high doses (low dose studies may be unavailable for this ingredient) RTECS®- Journal of Pharmacology and Experimental Therapeutics 1944
One or more animal studies show metabolic effects at high doses (low dose studies may be unavailable for this ingredient) RTECS®- Gigiena Truda i Professional'nye Zabolevaniya 1980
Classified as not expected to be potentially toxic or harmful Environment Canada Domestic Substance List
reproductive - weight of evidence unknown/unassessed/unreview: published lit review or major tox study National Library of Medicine HazMap

Developmental/reproductive toxicity

Type of concern: Reference:
Limited evidence of reproductive toxicity National Library of Medicine HazMap
One or more animal studies show reproductive effects at high doses RTECS®- Journal of Pharmaceutical Sciences 1972
One or more animal studies show developmental effects at high doses RTECS®- Journal of Pharmaceutical Sciences 1972
One or more animal studies show reproductive effects at high doses RTECS®- Journal of Dairy Science 1972

Persistence and bioaccumulation

Type of concern: Reference:
Persistent or bioaccumulative and moderate to high toxicity concern in humans Environment Canada Domestic Substance List
Not suspected to be bioaccumulative Environment Canada Domestic Substance List

Cancer

Type of concern: Reference:
Cancer - not classifiable/not likely to be human carcinogen EPA Integrated Risk Information System (IRIS)
One or more in vitro tests on mammalian cells show positive mutation results RTECS®- Farmakologiya i Toksikologiya (Moscow) 1977
One or more in vitro tests non-mammalian cells show positive mutation results RTECS®- Journal of Toxicology and Environmental Health 1985

Occupational hazards

Type of concern: Reference:
Allowed workplace exposures restricted to moderate doses RTECS®- TLV/BEI,2005
Allowed workplace exposures restricted to moderate doses RTECS®- TLV/BEI,2006
Allowed workplace exposures restricted to moderate doses RTECS®- TLV/BEI,2007

Neurotoxicity

Type of concern: Reference:
One or more animal studies show brain, nervous system, or behavioral effect effects at high doses RTECS®- Gigiena Truda i Professional'nye Zabolevaniya 1980

Ecotoxicology

Type of concern: Reference:
Wildlife and environmental toxicity EPA Clean Water Act - Priority Pollutants
Not suspected to be an environmental toxin Environment Canada Domestic Substance List



Government, industry, academic studies and classifications

government/industry list/academic study appears on list as classification(s)
Cosmetic Ingredient Review AssessmentsDIMETHYL PHTHALATE•Safe as used in cosmetics according to industry panel (Cosmetic Ingredient Review, CIR)
•Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product
•Determined safe for use in cosmetics based on concentrations of surrogate, related chemical in cosmetics, by industry safety panel (Cosmetic Ingredient Review, CIR)
EPA Clean Water Act - Priority PollutantsDIMETHYL PHTHALATE•Priority water pollutant under the Clean Water Act
Environment Canada Domestic Substance List1,2-BENZENEDICARBOXYLIC ACID, DIMETHYL ESTER•This chemical was deemed a moderate human health priority even though it did not meet the strict criteria of the categorization exercise of CEPA. The chemical was flagged for suspected persistence.
EPA Integrated Risk Information System (IRIS)DIMETHYL PHTHALATE•Group D: Not classifiable as to human carcinogenicity (EPA classification)
IFRA Fragrance Ingredient ListDIMETHYL PHTHALATE•The chemical has been reported as used in fragrance compounds by IFRA affiliated member companies in 2008.
EPA Hazardous Air PollutantsDIMETHYL PHTHALATE•Hazardous air pollutant under Clean Air Act
National Library of Medicine HazMapDIMETHYLPHTHALATE•Skin Sensitizer - An agent that can induce an allergic reaction in the skin or lungs: Yes;
•Reproductive Toxin - A chemical that is toxic to the reproductive system, including defects in the progeny and injury to male and female reproductive function: Yes;
•PEL (OSHA) - Permissible exposure limit (OSHA): 5 mg/m3;
•LC50 - Lethal concentration in 50% of animals tested: 22149 mg/m3;
•TLV (ACGIH) - Threshold limit value (ACGIH): 5 mg/m3;
•Flammability (NFPA) - NFPA flammability code: 0 = will not burn; 1 = must be preheated; 2 = high ambient temp required; 3 = may ignite at ambient temp; 4 = burn readily: 1: must be preheated;
•IDLH (NIOSH) - Immediately Dangerous to Life or Health: 2000 mg/m3;
EPA Categorized List of Inert Pesticide IngredientsDIMETHYL PHTHALATE•Pesticide inerts: potentially toxic, testing priority, according to EPA (Environmental Protection Agency)
EPA Toxic Release Inventory PBTsDIMETHYL ESTER1,2BENZENEDICARBOXYLIC ACID•Toxic, U.S. Environmental Protection Agency Toxics Release Inventory programs
US EPA, Air Risk Information Support CenterDIMETHYL PHTHALATE•Respiratory toxicity hazards: suspected
RTECS®- TLV/BEI,2005DIMETHYL PHTHALATE• occupationally related - ACGIH TLV (human TWA)
RTECS®- TLV/BEI,2006DIMETHYL PHTHALATE• occupationally related - ACGIH TLV (human TWA)
RTECS®- TLV/BEI,2007DIMETHYL PHTHALATE• occupationally related - ACGIH TLV (human TWA)
RTECS®- Farmakologiya i Toksikologiya (Moscow) 1977DIMETHYL PHTHALATE• mutagenic - Positive mutation assay: Cytogenetic Analysis (rat skn)
RTECS®- Farmakologiya i Toksikologiya (Moscow) 1977DIMETHYL PHTHALATE• mutagenic - Positive mutation assay: Cytogenetic Analysis (rat skn)
RTECS®- Gigiena i Sanitariya 1974DIMETHYL PHTHALATE• blood - Other changes (rat TCLo)
RTECS®- Gigiena Truda i Professional'nye Zabolevaniya 1980DIMETHYL PHTHALATE• metabolic - Weight loss or decreased weight gain (rat LD50)
• brain, nervous system, or behavioral effect - Somnolence (general depressed activity) (rat LD50)
• brain, nervous system, or behavioral effect - Withdrawal (rat LD50)
RTECS®- Journal of Dairy Science 1972DIMETHYL PHTHALATE• reproductive - Litter size (rat TDLo)
RTECS®- Journal of Pharmaceutical Sciences 1972DIMETHYL PHTHALATE• reproductive - Eye, ear (rat TDLo)
• reproductive - Fetal death (rat TDLo)
• developmental - Musculoskeletal system (rat TDLo)
• reproductive - Post-implantation mortality (rat TDLo)
RTECS®- Journal of Pharmacology and Experimental Therapeutics 1944DIMETHYL PHTHALATE• sense organ - Primary eye irritant (rabbit )
RTECS®- Journal of Pharmacology and Experimental Therapeutics 1944DIMETHYL PHTHALATE• sense organ - Primary eye irritant (rabbit )
RTECS®- Journal of Toxicology and Environmental Health 1985DIMETHYL PHTHALATE• mutagenic - Positive mutation assay: Mutation in Micro-organism (Salmonella typhimurium )
RTECS®- Journal of Toxicology and Environmental Health 1985DIMETHYL PHTHALATE• mutagenic - Positive mutation assay: Mutation in Micro-organism (Salmonella typhimurium )



references

government/industry list/academic study reference
Cosmetic Ingredient Review AssessmentsCIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
EPA Clean Water Act - Priority Pollutants
Environment Canada Domestic Substance ListEC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
EPA Integrated Risk Information System (IRIS)EPA (U.S. Environmental Protection Agency). 2008. Integrated Risk Information System (IRIS). Evidence for human carcinogenicity based on 1986-2005 guidelines.
IFRA Fragrance Ingredient ListIFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25
EPA Hazardous Air PollutantsEPA (U.S. Environmental Protection Agency). 2005. Office of Air. The 112(b)1 Hazardous Air Pollutants List (as modified). Last modified: 12 Dec 2005.
National Library of Medicine HazMapNLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
EPA Categorized List of Inert Pesticide IngredientsEPA (U.S. Environmental Protection Agency). 1987 & 2005. Office of Pesticide Programs. Inert (other) Pesticide Ingredients in Pesticide Products - Categorized List of Inert (other) Pesticide Ingredients.
EPA Toxic Release Inventory PBTsEPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
Scorecard.org Toxicity InformationUS EPA, Air Risk Information Support Center. Health Effects Notebook for Hazardous Air Pollutants. http://www.epa.gov/ttnatw01/hlthef/hapindex.html
RTECS®- TLV/BEI,2005RTECS®- TLV/BEI,2005
RTECS®- TLV/BEI,2006RTECS®- TLV/BEI,2006
RTECS®- TLV/BEI,2007RTECS®- TLV/BEI,2007
RTECS®- Farmakologiya i Toksikologiya (Moscow) 1977RTECS®- Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 40,454,1977
RTECS®- Farmakologiya i Toksikologiya (Moscow) 1977RTECS®- Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- 40,454,1977
RTECS®- Gigiena i Sanitariya 1974RTECS®- Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- 39(12),26,1974
RTECS®- Gigiena Truda i Professional'nye Zabolevaniya 1980RTECS®- Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI 24(3),25,1980
RTECS®- Journal of Dairy Science 1972RTECS®- Journal of Dairy Science. (American Dairy Science Assoc., 309 W. Clark St., Champaign, IL 61820) V.1- 1917- 55,696,1972
RTECS®- Journal of Pharmaceutical Sciences 1972RTECS®- Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- 61,51,1972
RTECS®- Journal of Pharmacology and Experimental Therapeutics 1944RTECS®- Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- 82,377,1944
RTECS®- Journal of Pharmacology and Experimental Therapeutics 1944RTECS®- Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 82,377,1944
RTECS®- Journal of Toxicology and Environmental Health 1985RTECS®- Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- 16,61,1985
RTECS®- Journal of Toxicology and Environmental Health 1985RTECS®- Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 16,61,1985

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