The Power of Information

National Drinking Water Database


National Drinking Water Database - Chemical Contaminants

Di(2-ethylhexyl) phthalate


Status: Regulated - EPA has established a maximum legal limit in tapwater for this contaminant.

Di(2-ethylhexyl) phthalate is a pollutant from rubber and industrial chemical factories and a leachate from PVC pipes; it is classified by EPA as a probable human carcinogen. [read more]

 
Detected
Found above
health guidelines
Found above
legal limit
States
38
38
27
Water utilities
1,620
1,620
139
People Served
28,991,459
28,991,459
922,815

Health Concerns for Di(2-ethylhexyl) phthalate:


Di(2-ethylhexyl) phthalate Exposure by State

Water utilities in 38 states have reported detecting Di(2-ethylhexyl) phthalate in treated tap water since 2004, according to EWG's analysis of water quality data supplied by state water agencies.

StateWater Suppliers with Di(2-ethylhexyl) phthalate contaminationWater suppliers reporting Di(2-ethylhexyl) phthalate above health-based limits
SystemsPopulationSystemsPopulation
Florida1075,253,9721075,253,972
Maryland3084,785,0763084,785,076
Arizona433,325,680433,325,680
New Jersey213,177,239213,177,239
California211,770,125211,770,125
Indiana991,665,854991,665,854
Nevada21,181,31421,181,314
Illinois901,014,598901,014,598
Pennsylvania31861,72331861,723
North Carolina127819,781127819,781
New York51819,65451819,654
New Mexico33702,56033702,560
Oregon28691,67728691,677
Delaware37351,35137351,351
Arkansas55288,91855288,918
Iowa87284,82287284,822
Minnesota34247,28334247,283
Massachusetts10234,71410234,714
Rhode Island13208,95313208,953
Alabama18181,07718181,077
Kentucky10164,93810164,938
Connecticut37141,44537141,445
Maine3140,4353140,435
Wisconsin128112,897128112,897
New Hampshire65100,22565100,225
Utah799,800799,800
Virginia999,690999,690
Nebraska2679,4822679,482
Washington1355,9611355,961
Idaho3549,8483549,848
Missouri1324,2771324,277
Montana3922,7023922,702
Texas913,457913,457
Vermont29,93929,939
Alaska15,87215,872
Ohio63,71363,713
Wyoming13751375
South Dakota132132
Total1,62028,991,4591,62028,991,459

The Most Polluted Communities

1,620 water utilities reported detecting Di(2-ethylhexyl) phthalate in tap water since 2004, according to EWG's analysis of water quality data supplied by state water agencies

Ranked by highest average Di(2-ethylhexyl) phthalate level

RankSystem Population Served Positive test results of total reported tests Average Level
(Range)
1River Villa Trailer Park
Menomonie, WI		601 of 118 ppb
(18 ppb)
2Country Club Estates Water System
Moses Lake, WA		1591 of 112.3 ppb
(12.3 ppb)
3Odell
Odell, IL		1,0141 of 19.1 ppb
(9.1 ppb)
4Pleasant Lake Mhp /Lower
Warner, NH		1501 of 18.8 ppb
(8.8 ppb)
5Exeter River Mhp
Exeter, NH		9801 of 28.5 ppb
(0 to 17 ppb)
6Androscoggin Ranger Station
NH		304 of 48.5 ppb
(2 to 18 ppb)
7St Pauls EV Lutheran School
Ixonia, WI		1001 of 27 ppb
(0 to 14 ppb)
8Little Red Elementary
Eau Claire, WI		1501 of 16.7 ppb
(6.7 ppb)
9Pine Garden Apartments
Woodstock, NY		321 of 16.4 ppb
(6.4 ppb)
10Wurtsboro Village Water Supply
Wurtsboro, NY		1,0601 of 16.2 ppb
(6.2 ppb)

Health Based Limits for Di(2-ethylhexyl) phthalate

StandardDescriptionLevel
Maximum Contaminant Limit Goal (MCLG)A non-enforceable health goal that is set at a level at which no known or anticipated adverse effect on the health of persons occurs and which allows an adequate margin of safety. Source: U.S. Environmental Protection Agency.0 ppb
One in one million (10-6) Cancer RiskThe concentration of a chemical in drinking water corresponding to an excess estimated lifetime cancer risk of 1 in 1,000,000. Source: U.S. Environmental Protection Agency.3 ppb
Maximum Contaminant Limit (MCL)The enforceable standard which defines the highest level of a contaminant that is allowed in drinking water. MCLs are set as close to health-based limits (Maximum Contaminant Level Goals, or MCLGs) as feasible using the best available analytical and treatment technologies and taking cost into consideration. Source: U.S. Environmental Protection Agency.6 ppb
California Public Health GoalsDefined by the State of California Office of Environmental Health Hazard Assessment (OEHHA) as the level of contaminant that is allowed in drinking water. For acutely toxic substances, levels are set at which scientific evidence indicates that no known or anticipated adverse effects on health will occur, plus an adequate margin-of safety. PHGs for carcinogens or other substances which can cause chronic disease shall be based solely on health effects without regard to cost impacts and shall be set at levels which OEHHA has determined do not pose any significant risk to health.12 ppb
One in ten thousand (10-4) Cancer RiskThe concentration of a chemical in drinking water corresponding to an excess estimated lifetime cancer risk of 1 in 10,000. Source: U.S. Environmental Protection Agency.300 ppb
Drinking Water Equivalent LevelA lifetime exposure concentration protective of adverse, noncarcinogenic health effects, that assumes all of the exposure to a contaminant is from drinking water. Source: U.S. Environmental Protection Agency.700 ppb

Testing Summary for Di(2-ethylhexyl) phthalate

Are tests routinely required for Di(2-ethylhexyl) phthalate by federal law?Yes
Water suppliers reporting tests for Di(2-ethylhexyl) phthalate (2004-2009):18,058 of 47,576
Average testing rate for water supplier reporting tests (2004-2009):0.5 per year

Violation Summary for Di(2-ethylhexyl) phthalate

Data from the U.S. Environmental Protection Agency includes the following violations of federal standards for Di(2-ethylhexyl) phthalate since 2004

Maximum Contaminant Level Exceedance Violations32
Monitoring Violations1,993
Reporting Violations0

Endocrine disruption

Type of concern: Reference:
Human endocrine disruptor - strong evidence European Commission on Endocrine Disruption
Limited evidence of endocrine disruption BKH/European Commission, 2000
One or more animal studies show endocrine system disruption at high doses RTECS®- Veterinary and Human Toxicology 1995
One or more animal studies show endocrine system disruption at high doses RTECS®- Toxicology and Applied Pharmacology 1981
One or more animal studies show endocrine system disruption at high doses RTECS®- Food and Cosmetics Toxicology 1977
endocrine - weight of evidence unknown/unassessed/unreview: published lit review or major tox study Illinois EPA Chemicals Associated with Endocrine System
endocrine - weight of evidence unknown/unassessed/unreview: published lit review or major tox study Our Stolen Future Endocrine Disruptors

Developmental/reproductive toxicity

Type of concern: Reference:
Possible human developmental toxicant California EPA Proposition 65
Limited evidence of reproductive toxicity European Union - Classification & Labelling
Limited evidence of reproductive toxicity National Library of Medicine HazMap
One or more animal studies show reproductive effects at moderate doses RTECS®- Food and Cosmetics Toxicology 1977
One or more animal studies show reproductive effects at high doses RTECS®- Toxicology and Applied Pharmacology 1973
One or more animal studies show reproductive effects at high doses RTECS®- Archives of Toxicology 1986
One or more animal studies show reproductive effects at high doses RTECS®- Nippon Eiseigaku Zasshi 1976
One or more animal studies show reproductive effects at high doses RTECS®- Indian Journal of Experimental Biology 1989
One or more animal studies show developmental effects at high doses RTECS®- Indian Journal of Experimental Biology 1989
One or more animal studies show reproductive effects at high doses RTECS®- Teratology, The International Journal of Abnormal Development 1987
One or more animal studies show developmental effects at high doses RTECS®- Teratology, The International Journal of Abnormal Development 1987

Cancer

Type of concern: Reference:
Possible human carcinogen EPA Integrated Risk Information System (IRIS)
Possible human carcinogen NTP Report on Carcinogens, 11th Edition
Limited evidence of carcinogenicity Amer Conf of Gov't Industrial Hygienists - Carcinogens
Limited evidence of carcinogenicity World Health Organization, International Agency for Research on Cancer
One or more in vitro tests on mammalian cells show positive mutation results RTECS®- Journal of Pharmaceutical Sciences 1976
One or more in vitro tests on mammalian cells show positive mutation results RTECS®- Mutation Research 1989
One or more in vitro tests on mammalian cells show positive mutation results RTECS®- Progress in Mutation Research 1985
One or more in vitro tests on mammalian cells show positive mutation results RTECS®- Proceedings of the American Association for Cancer Research 1986
One or more in vitro tests on mammalian cells show positive mutation results RTECS®- EHP, Environmental Health Perspectives 1986
One or more in vitro tests on mammalian cells show positive mutation results RTECS®- Toxicology and Applied Pharmacology 1988
One or more in vitro tests on mammalian cells show positive mutation results RTECS®- Mutation Research 1995
One or more in vitro tests on mammalian cells show positive mutation results RTECS®- Toxicology and Applied Pharmacology 1974
One or more in vitro tests on mammalian cells show positive mutation results RTECS®- Journal of Toxicology and Environmental Health 1985
One or more in vitro tests on mammalian cells show positive mutation results RTECS®- EHP, Environmental Health Perspectives 1982
One or more in vitro tests on mammalian cells show positive mutation results RTECS®- Science 1987
One or more in vitro tests on mammalian cells show positive mutation results RTECS®- Environmental and Molecular Mutagenesis 2000
One or more in vitro tests on mammalian cells show positive mutation results RTECS®- Food and Chemical Toxicology 2004
One or more in vitro tests non-mammalian cells show positive mutation results RTECS®- EHP, Environmental Health Perspectives 1982
One or more in vitro tests non-mammalian cells show positive mutation results RTECS®- Mutation Research 1991
One or more in vitro tests non-mammalian cells show positive mutation results RTECS®- Mutation Research 1989
One or more in vitro tests non-mammalian cells show positive mutation results RTECS®- Progress in Mutation Research 1985
One or more in vitro tests non-mammalian cells show positive mutation results RTECS®- Mutagenesis 2004
One or more animal studies show tumor formation at high doses RTECS®- National Toxicology Program Technical Report Series 1982
One or more animal studies show tumor formation at high doses RTECS®- Carcinogenesis (London) 1983
One or more animal studies show tumor formation at high doses RTECS®- EHP, Environmental Health Perspectives 1986
One or more animal studies show tumor formation at high doses RTECS®- Cancer Letters (Shannon, Ireland) 1987
One or more animal studies show tumor formation at high doses RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 1999
One or more animal studies show tumor formation at high doses RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2000
One or more animal studies show tumor formation at high doses RTECS®- National Technical Information Service 4011
One or more animal studies show tumor formation at high doses RTECS®- Journal of Toxicologic Pathology 2001

Organ system toxicity (non-reproductive)

Type of concern: Reference:
Known human respiratory toxicant EPA Hazardous Air Pollutants
One or more animal studies show classified as toxic effects at low doses EPA Categorized List of Inert Pesticide Ingredients
One or more animal studies show respiratory effects at low doses RTECS®- Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv 1961
One or more animal studies show blood effects at low doses RTECS®- Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv 1961
Limited evidence of gastrointestinal or liver toxicity US EPA, Air Risk Information Support Center, 2003
Limited evidence of respiratory toxicity California EPA, Office of Environmental Health Hazard Assessment, 2003
One or more animal studies show effects at moderate doses (low dose studies may be unavailable for this ingredient) EPA Categorized List of Inert Pesticide Ingredients
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient) EPA Toxic Release Inventory PBTs
One or more animal studies show respiratory effects at moderate doses (low dose studies may be unavailable for this ingredient) RTECS®- Toxicology and Applied Pharmacology 1978
One or more animal studies show respiratory effects at moderate doses (low dose studies may be unavailable for this ingredient) RTECS®- Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv 1961
One or more animal studies show gastrointestinal effects at moderate doses (low dose studies may be unavailable for this ingredient) RTECS®- Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv 1961
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient) RTECS®- National Technical Information Service
One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient) RTECS®- American Journal of Ophthalmology 1946
One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient) RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J 1986
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient) RTECS®- Raw Material Data Handbook, Vol 1975
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient) RTECS®- Journal of Industrial Hygiene and Toxicology 1945
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient) RTECS®- Gigiena Truda i Professional'nye Zabolevaniya 1988
One or more animal studies show cardiovascular effects at high doses (low dose studies may be unavailable for this ingredient) RTECS®- Journal of Pharmaceutical Sciences 1966
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient) RTECS®- EHP, Environmental Health Perspectives 1973
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient) RTECS®- IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man 1982
One or more animal studies show metabolic effects at high doses (low dose studies may be unavailable for this ingredient) RTECS®- Toxicology Letters 1979
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient) RTECS®- Toxicology Letters 1979
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient) RTECS®- Veterinary and Human Toxicology 1995
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient) RTECS®- AMA Archives of Industrial Hygiene and Occupational Medicine 1953
One or more animal studies show kidney or renal system effects at high doses (low dose studies may be unavailable for this ingredient) RTECS®- AMA Archives of Industrial Hygiene and Occupational Medicine 1953
One or more animal studies show metabolic effects at high doses (low dose studies may be unavailable for this ingredient) RTECS®- AMA Archives of Industrial Hygiene and Occupational Medicine 1953
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient) RTECS®- Toxicology and Applied Pharmacology 1981
One or more animal studies show kidney or renal system effects at high doses (low dose studies may be unavailable for this ingredient) RTECS®- Food and Cosmetics Toxicology 1977
One or more animal studies show metabolic effects at high doses (low dose studies may be unavailable for this ingredient) RTECS®- Food and Cosmetics Toxicology 1977
One or more animal studies show blood effects at high doses (low dose studies may be unavailable for this ingredient) RTECS®- Food and Cosmetics Toxicology 1977
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient) RTECS®- Food and Cosmetics Toxicology 1977
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient) RTECS®- Toxicology and Applied Pharmacology 1985
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient) RTECS®- Toxicology Letters 1993
reproductive - weight of evidence unknown/unassessed/unreview: published lit review or major tox study National Library of Medicine HazMap
Classified as not expected to be potentially toxic or harmful Environment Canada Domestic Substance List
Classified as a low human health priority Environment Canada Domestic Substance List

Neurotoxicity

Type of concern: Reference:
One or more animal studies show brain, nervous system, or behavioral effect effects at low doses RTECS®- Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv 1961
One or more animal studies show brain, nervous system, or behavioral effect effects at moderate doses RTECS®- Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv 1961
One or more animal studies show brain, nervous system, or behavioral effect effects at high doses RTECS®- Journal of Pharmaceutical Sciences 1966

Persistence and bioaccumulation

Type of concern: Reference:
Persistent, bioaccumulative in wildlife Canada PBTs - Accelerated Reduction/Elimination of Toxics (ARET)
Persistent, bioaccumulative in wildlife OSPAR PBTs - Substances of Possible Concern
Persistent, bioaccumulative in wildlife Emerging PBTs from peer-reviewed literature
Not suspected to be persistent Environment Canada Domestic Substance List
Not suspected to be bioaccumulative Environment Canada Domestic Substance List

Occupational hazards

Type of concern: Reference:
Allowed workplace exposures restricted to moderate doses RTECS®- TLV/BEI,2005
Allowed workplace exposures restricted to moderate doses RTECS®- TLV/BEI,2006
Allowed workplace exposures restricted to moderate doses RTECS®- TLV/BEI,2007

Biochemical or cellular level changes

Type of concern: Reference:
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood RTECS®- Veterinary and Human Toxicology 1995
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood RTECS®- Toxicology and Applied Pharmacology 1981
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood RTECS®- Toxicology and Applied Pharmacology 1985

Irritation (skin, eyes, or lungs)

Type of concern: Reference:
One or more animal studies show skin irritation at moderate doses RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J 1986
One or more animal studies show skin irritation at high doses RTECS®- Gigiena i Sanitariya 1980
One or more animal studies show skin irritation at high doses RTECS®- Food and Cosmetics Toxicology 1977

Ecotoxicology

Type of concern: Reference:
Wildlife and environmental toxicity EPA Clean Water Act - Priority Pollutants
Wildlife and environmental toxicity Illinois EPA Chemicals Associated with Endocrine System
Wildlife and environmental toxicity European Union - Water Framework Directive
Suspected to be an environmental toxin Environment Canada Domestic Substance List



Government, industry, academic studies and classifications

government/industry list/academic study appears on list as classification(s)
European Union - Classification & LabellingBIS(2-ETHYLHEXYL) PHTHALATE•May be toxic to the reproductive system
•May impair fertility
Amer Conf of Gov't Industrial Hygienists - CarcinogensDI(2-ETHYLHEXYL)PHTHALATE (DEHP)•Confirmed animal carcinogen with unknown relevance to humans (ACGIH classification A3)
Association of Occupational and Environmental ClinicsDIOCTYLPHTHALATE• o
EPA Clean Water Act - Priority PollutantsBIS(2-ETHYLHEXYL)PHTHALATE•Priority water pollutant under the Clean Water Act
Environment Canada Domestic Substance List1,2-BENZENEDICARBOXYLIC ACID, BIS(2-ETHYLHEXYL) ESTER•This chemical was NOT flagged by CEPA for further attention. The chemical was flagged as a low human health priority and for suspected aquatic toxicity.
Illinois EPA Chemicals Associated with Endocrine SystemDI(2-ETHYLHEXYL)PHTHALATE•EPA: probable endocrine disruptor
EPA Integrated Risk Information System (IRIS)DI (2-ETHYLHEXYL)PHTHALATE (DEHP)•Group B2: Probable human carcinogen - sufficient data in animals (EPA classification)
European Commission on Endocrine DisruptionDI-(2-ETHYLHEXYL)PHTHALATE (DEHP)HH-CAT1;WF-CAT3
European Union - Banned or Restricted in CosmeticsBIS(2-ETHYLHEXYL) PHTHALATE•Prohibited in EU cosmetics: must not form part of the composition of cosmetic products
European Union - Water Framework DirectiveDI(2-ETHYLHEXYL)PHTHALATE (DEHP)•Priority substance in EU water policy
IFRA Fragrance Ingredient ListDI(2-ETHYLHEXYL) PHTHALATE•The chemical has been reported as used in fragrance compounds by IFRA affiliated member companies in 2008.
EPA Hazardous Air PollutantsBIS(2-ETHYLHEXYL)PHTHALATE (DEHP)•Hazardous air pollutant under Clean Air Act
National Library of Medicine HazMapDI-SEC-OCTYL PHTHALATE•Reproductive Toxin - A chemical that is toxic to the reproductive system, including defects in the progeny and injury to male and female reproductive function: Yes;
•PEL (OSHA) - Permissible exposure limit (OSHA): 5 mg/m3;
•TLV (ACGIH) - Threshold limit value (ACGIH): 5 mg/m3;
•Flammability (NFPA) - NFPA flammability code: 0 = will not burn; 1 = must be preheated; 2 = high ambient temp required; 3 = may ignite at ambient temp; 4 = burn readily: 1: must be preheated;
•IDLH (NIOSH) - Immediately Dangerous to Life or Health: 5000 mg/m3;
•MAK - Maximum Allowable Concentration (Federal Republic of Germany): 10 mg/m3;
EPA Categorized List of Inert Pesticide IngredientsDIOCTYL PHTHALATE•Pesticide inerts: potentially toxic, testing priority, according to EPA (Environmental Protection Agency)
EPA Categorized List of Inert Pesticide IngredientsPHTHALIC ACID, BIS(2-ETHYLHEXYL) ESTER C1980•Pesticide inerts of toxicological concern according to EPA (Environmental Protection Agency)
NTP Report on Carcinogens, 11th EditionDI(2-ETHYLHEXYL) PHTHALATE•Reasonably anticipated to be a human carcinogen (National Toxicology Program classification)
NTP - Risks to Human ReproductionDI(2-ETHYLHEXYL) PHTHALATE<>
Our Stolen Future Endocrine DisruptorsDI-ETHYLHEXYL PHTHALATE (DEHP)•
Canada PBTs - Accelerated Reduction/Elimination of Toxics (ARET)BIS(2-ETHYLHEXYL) ESTER1,2-BENZENEDICARBOXYLIC ACID•Bioaccumulative toxicant under Canada's Accelerated Reduction/Elimination of Toxics program - targeted for elimination or reduction
OSPAR PBTs - Substances of Possible ConcernBIS(2-ETHYLHEXYL) ESTER1,2-BENZENEDICARBOXYLIC ACID•Persistent, bioaccumulative toxicant - Oslo-Paris (OSPAR) Convention for the Protection of the Marine Environment of the North-East Atlantic, chemical of concern
Emerging PBTs from peer-reviewed literature1,2-BENZENEDICARBOXYLIC ACID, BIS(2-ETHYLHEXYL) ESTER•Persistent, bioaccumulative toxicant - Limited or emerging evidence in open scientific literature
EPA Toxic Release Inventory PBTsBIS(2-ETHYLHEXYL) ESTER1,2-BENZENEDICARBOXYLIC ACID•Toxic, U.S. Environmental Protection Agency Toxics Release Inventory programs
World Health Organization, International Agency for Research on CancerDI(2-ETHYLHEXYL)PHTHALATEIARC Group 2B
California EPA Proposition 65DI(2-ETHYLHEXYL)PHTHALATE•Developmental toxin: California Proposition 65
•Reproductive toxin, male: California Proposition 65
BKH/European Commission, 2000BIS(2-ETHYLHEXYL)PHTHALATE•Endocrine toxicity hazards: suspected
US EPA, Air Risk Information Support Center, 2003BIS(2-ETHYLHEXYL)PHTHALATE•Gastrointestinal or liver toxicity hazards: suspected
California EPA, Office of Environmental Health Hazard Assessment, 2003BIS(2-ETHYLHEXYL)PHTHALATE•Respiratory toxicity hazards: suspected
RTECS®- TLV/BEI,2005DIETHYLHEXYL PHTHALATE• occupationally related - ACGIH TLV (human TWA)
RTECS®- TLV/BEI,2006DIETHYLHEXYL PHTHALATE• occupationally related - ACGIH TLV (human TWA)
RTECS®- TLV/BEI,2007DIETHYLHEXYL PHTHALATE• occupationally related - ACGIH TLV (human TWA)
RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J 1986DIETHYLHEXYL PHTHALATE• sense organ - Primary eye irritant (rabbit )
• skin - Primary skin irritant (rabbit )
RTECS®- AMA Archives of Industrial Hygiene and Occupational Medicine 1953DIETHYLHEXYL PHTHALATE• metabolic - Weight loss or decreased weight gain (rat TDLo)
• kidney or renal system - Changes in bladder weight (rat TDLo)
• liver - Changes in liver weight (rat TDLo)
RTECS®- American Journal of Ophthalmology 1946DIETHYLHEXYL PHTHALATE• sense organ - Primary eye irritant (rabbit )
RTECS®- American Journal of Ophthalmology 1946DIETHYLHEXYL PHTHALATE• sense organ - Primary eye irritant (rabbit )
RTECS®- Archives of Toxicology 1986DIETHYLHEXYL PHTHALATE• reproductive - Prostate, seminal vesicle, Cowper's gland, accessory glands (rat TDLo)
• reproductive - Testes, epididymis, sperm duct (rat TDLo)
RTECS®- Cancer Letters (Shannon, Ireland) 1987DIETHYLHEXYL PHTHALATE• cancer - liver tumors (rat TD)
RTECS®- Carcinogenesis (London) 1983DIETHYLHEXYL PHTHALATE• cancer - liver tumor formations - equivocal (mouse TD)
RTECS®- EHP, Environmental Health Perspectives 1982DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: Mutation in Micro-organism (Salmonella typhimurium )
• mutagenic - Positive mutation assay: Cytogenetic Analysis (hamster orl)
• mutagenic - Positive mutation assay: Morphological Transform (hamster orl)
RTECS®- EHP, Environmental Health Perspectives 1986DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: sperm (rat orl)
RTECS®- EHP, Environmental Health Perspectives 1973DIETHYLHEXYL PHTHALATE• broad systemic - Broad systemic toxicity (guinea pig LD50)
RTECS®- EHP, Environmental Health Perspectives 1982DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: Mutation in Micro-organism (Salmonella typhimurium )
• mutagenic - Positive mutation assay: Cytogenetic Analysis (hamster orl)
• mutagenic - Positive mutation assay: Morphological Transform (hamster orl)
RTECS®- EHP, Environmental Health Perspectives 1986DIETHYLHEXYL PHTHALATE• cancer - liver tumors (mouse TD)
RTECS®- EHP, Environmental Health Perspectives 1986DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: sperm (rat orl)
RTECS®- Environmental and Molecular Mutagenesis 2000DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: Morphological Transform (mouse fbr)
RTECS®- Environmental and Molecular Mutagenesis 2000DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: Morphological Transform (mouse fbr)
RTECS®- Food and Chemical Toxicology 2004DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: DNA Damage (rat orl)
RTECS®- Food and Chemical Toxicology 2004DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: DNA Damage (rat orl)
RTECS®- Food and Cosmetics Toxicology 1977DIETHYLHEXYL PHTHALATE• reproductive - Ovaries, fallopian tubes (rat TDLo)
• metabolic - Weight loss or decreased weight gain (rat TDLo)
• kidney or renal system - Changes in bladder weight (rat TDLo)
• liver - Changes in liver weight (rat TDLo)
• endocrine system - Changes in testicular weight (rat TDLo)
• skin - Hair (rat TDLo)
• blood - Other changes (rat TDLo)
RTECS®- Gigiena i Sanitariya 1980DIETHYLHEXYL PHTHALATE• skin - Other glands (rat LDLo)
RTECS®- Gigiena Truda i Professional'nye Zabolevaniya 1988DIETHYLHEXYL PHTHALATE• broad systemic - Broad systemic toxicity (mouse LD50)
RTECS®- IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man 1982DIETHYLHEXYL PHTHALATE• broad systemic - Broad systemic toxicity (guinea pig LD50)
RTECS®- Indian Journal of Experimental Biology 1989DIETHYLHEXYL PHTHALATE• reproductive - Fetotoxicity (rat TDLo)
• developmental - Hepatobiliary system (rat TDLo)
RTECS®- Journal of Industrial Hygiene and Toxicology 1945DIETHYLHEXYL PHTHALATE• broad systemic - Broad systemic toxicity (rabbit LD50)
RTECS®- Journal of Pharmaceutical Sciences 1976DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: Cytogenetic Analysis ( human leu)
RTECS®- Journal of Pharmaceutical Sciences 1966DIETHYLHEXYL PHTHALATE• cardiovascular - BP lowering not characterized in autonomic section (mouse LD50)
• brain, nervous system, or behavioral effect - Excitement (mouse LD50)
RTECS®- Journal of Pharmaceutical Sciences 1976DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: Cytogenetic Analysis ( human leu)
RTECS®- Journal of Toxicologic Pathology 2001DIETHYLHEXYL PHTHALATE• cancer - liver neoplasms (mouse TDLo)
RTECS®- Journal of Toxicology and Environmental Health 1985DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: Dominant Lethal Strain (mouse scu)
RTECS®- Journal of Toxicology and Environmental Health 1985DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: Dominant Lethal Strain (mouse scu)
RTECS®- Mutagenesis 2004DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: Mutation in Micro-organism (Saccharomyces cerevisiae )
RTECS®- Mutation Research 1989DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: Sister Chromatid Exchange ( human lym)
RTECS®- Mutation Research 1989DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: (Drosophila melanogaster orl)
RTECS®- Mutation Research 1991DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: Phage Inhibition Capacity (Escherichia coli )
RTECS®- Mutation Research 1995DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: other mutation test systems (mouse orl)
RTECS®- Mutation Research 1989DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: Sister Chromatid Exchange ( human lym)
RTECS®- Mutation Research 1989DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: (Drosophila melanogaster orl)
RTECS®- Mutation Research 1991DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: Phage Inhibition Capacity (Escherichia coli )
RTECS®- Mutation Research 1995DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: other mutation test systems (mouse orl)
RTECS®- National Technical Information Service DIETHYLHEXYL PHTHALATE• broad systemic - Broad systemic toxicity (mouse LD50)
RTECS®- National Technical Information Service 4011DIETHYLHEXYL PHTHALATE• cancer - liver tumors (mouse TDLo)
RTECS®- National Toxicology Program Technical Report Series 1982DIETHYLHEXYL PHTHALATE• mutagenic - endocrine system tumors (rat TDLo)
• cancer - liver tumors (rat TDLo)
• mutagenic - reproductive tumors (rat TD)
RTECS®- Nippon Eiseigaku Zasshi 1976DIETHYLHEXYL PHTHALATE• reproductive - Post-implantation mortality (rat TDLo)
RTECS®- Proceedings of the American Association for Cancer Research 1986DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: Unscheduled DNA Synthesis (rat orl)
RTECS®- Proceedings of the American Association for Cancer Research 1986DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: Unscheduled DNA Synthesis (rat orl)
RTECS®- Progress in Mutation Research 1985DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: Gene Conversion and Mitotic Recombination (Saccharomyces cerevisiae )
RTECS®- Progress in Mutation Research 1985DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: Mutation in Micro-organism (Saccharomyces cerevisiae )
RTECS®- Progress in Mutation Research 1985DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: Unscheduled DNA Synthesis (rat lvr)
RTECS®- Progress in Mutation Research 1985DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: Sex Chromosome Loss and Nondisjunction (hamster lvr)
RTECS®- Progress in Mutation Research 1985DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: Mutation in Micro-organism (mouse lym)
RTECS®- Progress in Mutation Research 1985DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: Morphological Transform (hamster emb)
RTECS®- Progress in Mutation Research 1985DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: Gene Conversion and Mitotic Recombination (Saccharomyces cerevisiae )
RTECS®- Progress in Mutation Research 1985DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: Mutation in Micro-organism (Saccharomyces cerevisiae )
RTECS®- Progress in Mutation Research 1985DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: Unscheduled DNA Synthesis (rat lvr)
RTECS®- Progress in Mutation Research 1985DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: Sex Chromosome Loss and Nondisjunction (hamster lvr)
RTECS®- Progress in Mutation Research 1985DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: Mutation in Micro-organism (mouse lym)
RTECS®- Progress in Mutation Research 1985DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: Morphological Transform (hamster emb)
RTECS®- Raw Material Data Handbook, Vol 1975DIETHYLHEXYL PHTHALATE• broad systemic - Broad systemic toxicity (rat LD50)
RTECS®- Science 1987DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: Sister Chromatid Exchange (hamster ovr)
RTECS®- Science 1987DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: Sister Chromatid Exchange (hamster ovr)
RTECS®- Teratology, The International Journal of Abnormal Development 1987DIETHYLHEXYL PHTHALATE• reproductive - Musculoskeletal system (rat TDLo)
• developmental - Urogenital system (rat TDLo)
RTECS®- Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv 1961DIETHYLHEXYL PHTHALATE• blood - Hemorrhage (rat LDLo)
• gastrointestinal - Necrotic changes (mouse LD50)
• brain, nervous system, or behavioral effect - Somnolence (general depressed activity) (rat LDLo)
• respiratory - Structural or functional change in trachea or bronchi (rat LDLo)
RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 1999DIETHYLHEXYL PHTHALATE• cancer - liver tumors (rat TD)
RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2000DIETHYLHEXYL PHTHALATE• cancer - gastrointestinal neoplasms (rat TDLo)
RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2000DIETHYLHEXYL PHTHALATE
RTECS®- Toxicology and Applied Pharmacology 1973DIETHYLHEXYL PHTHALATE• reproductive - Fetotoxicity (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 1974DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: Dominant Lethal Strain (mouse ipr)
RTECS®- Toxicology and Applied Pharmacology 1978DIETHYLHEXYL PHTHALATE• respiratory - Other changes (rat LD50)
RTECS®- Toxicology and Applied Pharmacology 1981DIETHYLHEXYL PHTHALATE• liver - Changes in liver weight (rat TDLo)
• endocrine system - Changes in testicular weight (rat TDLo)
• biochemical - Dehydrogenases (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 1985DIETHYLHEXYL PHTHALATE• biochemical - Catalases (rat TDLo)
• liver - Changes in liver weight (rat TDLo)
• biochemical - Phosphatases (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 1988DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: Unscheduled DNA Synthesis (mouse orl)
RTECS®- Toxicology and Applied Pharmacology 1974DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: Dominant Lethal Strain (mouse ipr)
RTECS®- Toxicology and Applied Pharmacology 1988DIETHYLHEXYL PHTHALATE• mutagenic - Positive mutation assay: Unscheduled DNA Synthesis (mouse orl)
RTECS®- Toxicology Letters 1979DIETHYLHEXYL PHTHALATE• metabolic - Weight loss or decreased weight gain (mouse TDLo)
• broad systemic - Broad systemic toxicity (mouse LD50)
RTECS®- Toxicology Letters 1993DIETHYLHEXYL PHTHALATE• liver - Changes in liver weight (rat TDLo)
• liver - Other changes (rat TDLo)
RTECS®- Veterinary and Human Toxicology 1995DIETHYLHEXYL PHTHALATE• endocrine system - Changes in testicular weight (rat TDLo)
• biochemical - Dehydrogenases (rat TDLo)
• liver - Other changes (rat TDLo)



references

government/industry list/academic study reference
European Union - Classification & LabellingCPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
Amer Conf of Gov't Industrial Hygienists - CarcinogensACGIH (American Conference of Governmental Industrial Hygienists) 2008. ACGIH cancer classification system. www.acgih.org.
Association of Occupational and Environmental ClinicsAOEC (Association of Occupational and Environmental Clinics). 2009. AEOC exposures codes and asthmagen designation.
EPA Clean Water Act - Priority Pollutants
Environment Canada Domestic Substance ListEC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
Illinois EPA Chemicals Associated with Endocrine SystemIllinois EPA (Illinois Environmental Protection Agency). 2000. Preliminary list of chemicals associated with endocrine system effects in animals and humans (*) or in vitro (+). In EPA (U.S. Environmental Protection Agency) 2000. Handbook for Non-Cancer Health Effects Valuation, Appendix C.
EPA Integrated Risk Information System (IRIS)EPA (U.S. Environmental Protection Agency). 2008. Integrated Risk Information System (IRIS). Evidence for human carcinogenicity based on 1986-2005 guidelines.
European Commission on Endocrine DisruptionEU (European Union)- Strategy for Endocrine Disrupters 2007. Commision on endocrin disruption requested by the European Parliament in 1998.
European Union - Banned or Restricted in CosmeticsEC (European Commission of the European Union). 1999-2006. Enterprise Directorate-General Pharmaceuticals and Cosmetics. The rules governing cosmetic products in the European Union, Volume 1, "Cosmetics legislation."
European Union - Water Framework DirectiveEU (European Union). 2000. Water Framework Directive (Directive 2000/60/EC ) - integrated river basin management for Europe. List of priority substances.
IFRA Fragrance Ingredient ListIFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25
EPA Hazardous Air PollutantsEPA (U.S. Environmental Protection Agency). 2005. Office of Air. The 112(b)1 Hazardous Air Pollutants List (as modified). Last modified: 12 Dec 2005.
National Library of Medicine HazMapNLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
EPA Categorized List of Inert Pesticide IngredientsEPA (U.S. Environmental Protection Agency). 1987 & 2005. Office of Pesticide Programs. Inert (other) Pesticide Ingredients in Pesticide Products - Categorized List of Inert (other) Pesticide Ingredients.
NTP Report on Carcinogens, 11th EditionNTP (National Toxicology Program). 2005. Report on Carcinogens, Eleventh Edition; U.S. Department of Health and Human Services, Public Health Service, National Toxicology Program.
NTP - Risks to Human ReproductionNTP (National Toxicology Program). 2006. NTP Center for the Evaluation fo Risks to Human Reproduction (CERHR). NTP-CERHR Reports and Monographs.
Our Stolen Future Endocrine DisruptorsColborn T, D Dumanoski, JP Myers. 2006. Widespread Pollutants with Endocrine-disrupting Effects. Updated from original listing in "Our Stolen Future" (1996).
Canada PBTs - Accelerated Reduction/Elimination of Toxics (ARET)EC (Environment Canada). 1994. Accelerated Reduction/Elimination of Toxics (ARET). ARET substance list of persistent, bioaccumulative and toxic chemicals.
OSPAR PBTs - Substances of Possible ConcernOSPAR (Oslo-Paris). 2002. OSPAR List of Substances of Possible Concern. Secondary OSPAR List of Substances of Possible Concern. Secondary OSPAR. Place Published, OSPAR Convention for the Protection of the Marine Environement of North-East Atlanic.
Emerging PBTs from peer-reviewed literatureEmerging PBTs from peer-reviewed literature
EPA Toxic Release Inventory PBTsEPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
Open scientific literatureWorld Health Organization, International Agency for Research on Cancer. IARC Monographs Programme on the Evaluation of Carcinogenic Risks to Humans. Lists of Group 1, 2a, and 2b substances can be obtained. http://monographs.iarc.fr/ENG/Classification/index.php
California EPA Proposition 65California EPA (California Environmental Protection Agency). 9/2008. Office of Environmental Health Hazard Assessment. Safe Drinking Water and Toxic Enforcement Act of 1986. Chemicals known to the State to cause cancer or reproductive toxicity.
Scorecard.org Toxicity InformationBKH/European Commission. Towards the establishment of a priority list of substances for further evaluation of their role in endocrine disruption: - preparation of a candidate list of substances as a basis for priority setting. Final report-November 2000. http://europa.eu.int/comm/environment/docum/01262_en.htm#bkh. Category 1 chemicals from Annex 1: Candidate list of 553 substances. http://europa.eu.int/comm/environment/docum/bkh_annex_01.pdf, Brucker-Davis, F. Effects of Environmental Synthetic Chemicals on Thyroid Function. Thyroid. 8(9): 827-856. 1998., Illinois EPA. Endocrine Disruptors Strategy. 1997. (Table 1: Preliminary List of Chemicals Associated with Endocrine System Effects in Animals and Humans or In Vitro). http://www.nihs.go.jp/hse/environ/illiepatable.htm, Japanese National Institute of Health Sciences. Lists of Paradigmatic Chemicals. http://www.nihs.go.jp/hse/endocrine-e/paradigm/paradigm.html, Keith, L.H. (ed.). Environmental Endocrine Disruptors. John Wiley & Sons, NY. 1997. http://www.wileyeurope.com/cda/product/0,,0471191450%7Cdesc%7C3037,00.html, World Wildlife Fund. Our Stolen Future. Widespread Pollutants with Endocrine-disrupting Effects. http://www.ourstolenfuture.org/Basics/chemlist.htm. The WWF list is derived from references detailed at http://www.ourstolenfuture.org/Sources/chemsources.htm and was originally published in: Colborn, T., F.S. vom Saal, and A.M. Soto. Developmental Effects of Endocrine-Disrupting Chemicals In Wildlife and Humans. Environmental Health Perspectives 101(5): 378-384. 1993.
Scorecard.org Toxicity InformationUS EPA, Air Risk Information Support Center. Health Effects Notebook for Hazardous Air Pollutants. http://www.epa.gov/ttnatw01/hlthef/hapindex.html, California EPA, Office of Environmental Health Hazard Assessment. Air Toxics Hot Spots Program Risk Assessment Guidelines, Part III: Technical Support Document 'Determination of Noncancer Chronic Reference Exposure Levels'. Includes all Chronic Reference Exposure Levels (CRELs) adopted by OEHHA as of August 2003 (http://www.oehha.ca.gov/air/chronic_rels/AllChrels.html, plus draft CRELS proposed through March 2004 (http://www.oehha.ca.gov/air/chronic_rels/index.html., National Institute for Occupational Safety and Health's Registry of Toxic Effects of Chemical Substances. See Environmental Defense's Suspect Hazard Identification documentation.
Scorecard.org Toxicity InformationCalifornia EPA, Office of Environmental Health Hazard Assessment. Air Toxics Hot Spots Program Risk Assessment Guidelines, Part III: Technical Support Document 'Determination of Noncancer Chronic Reference Exposure Levels'. Includes all Chronic Reference Exposure Levels (CRELs) adopted by OEHHA as of August 2003 (http://www.oehha.ca.gov/air/chronic_rels/AllChrels.html, plus draft CRELS proposed through March 2004 (http://www.oehha.ca.gov/air/chronic_rels/index.html., National Institute for Occupational Safety and Health's Registry of Toxic Effects of Chemical Substances. See Environmental Defense's Suspect Hazard Identification documentation.
RTECS®- TLV/BEI,2005RTECS®- TLV/BEI,2005
RTECS®- TLV/BEI,2006RTECS®- TLV/BEI,2006
RTECS®- TLV/BEI,2007RTECS®- TLV/BEI,2007
RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J 1986RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 -,389,1986
RTECS®- AMA Archives of Industrial Hygiene and Occupational Medicine 1953RTECS®- AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. 8,219,1953
RTECS®- American Journal of Ophthalmology 1946RTECS®- American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N. Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 1918- 29,1363,1946
RTECS®- American Journal of Ophthalmology 1946RTECS®- American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N. Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 29,1363,1946
RTECS®- Archives of Toxicology 1986RTECS®- Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- 59,290,1986
RTECS®- Cancer Letters (Shannon, Ireland) 1987RTECS®- Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- 38,15,1987
RTECS®- Carcinogenesis (London) 1983RTECS®- Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- 4,1021,1983
RTECS®- EHP, Environmental Health Perspectives 1982RTECS®- EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 45,119,1982
RTECS®- EHP, Environmental Health Perspectives 1986RTECS®- EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 65,343,1986
RTECS®- EHP, Environmental Health Perspectives 1973RTECS®- EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- 4,3,1973
RTECS®- EHP, Environmental Health Perspectives 1982RTECS®- EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- 45,119,1982
RTECS®- EHP, Environmental Health Perspectives 1986RTECS®- EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- 65,271,1986
RTECS®- EHP, Environmental Health Perspectives 1986RTECS®- EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- 65,343,1986
RTECS®- Environmental and Molecular Mutagenesis 2000RTECS®- Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- 35,300,2000
RTECS®- Environmental and Molecular Mutagenesis 2000RTECS®- Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 35,300,2000
RTECS®- Food and Chemical Toxicology 2004RTECS®- Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 42,107,2004
RTECS®- Food and Chemical Toxicology 2004RTECS®- Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- 42,107,2004
RTECS®- Food and Cosmetics Toxicology 1977RTECS®- Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. 15,389,1977
RTECS®- Gigiena i Sanitariya 1980RTECS®- Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- 45(6),35,1980
RTECS®- Gigiena Truda i Professional'nye Zabolevaniya 1988RTECS®- Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI 32(7),52,1988
RTECS®- IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man 1982RTECS®- IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- 29,269,1982
RTECS®- Indian Journal of Experimental Biology 1989RTECS®- Indian Journal of Experimental Biology. (Publications & Information Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- 27,885,1989
RTECS®- Journal of Industrial Hygiene and Toxicology 1945RTECS®- Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. 27,130,1945
RTECS®- Journal of Pharmaceutical Sciences 1976RTECS®- Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 65,1648,1976
RTECS®- Journal of Pharmaceutical Sciences 1966RTECS®- Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- 55,158,1966
RTECS®- Journal of Pharmaceutical Sciences 1976RTECS®- Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- 65,1648,1976
RTECS®- Journal of Toxicologic Pathology 2001RTECS®- Journal of Toxicologic Pathology. (Nihon Dokusei Byori Gakkai, editor, 3-25-8 Nishi- shinbashi, Minato-ku, Tokyo 105, Japan) V.1- 1988 29,458,2001
RTECS®- Journal of Toxicology and Environmental Health 1985RTECS®- Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- 16,71,1985
RTECS®- Journal of Toxicology and Environmental Health 1985RTECS®- Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 16,71,1985
RTECS®- Mutagenesis 2004RTECS®- Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 20,105,2004
RTECS®- Mutation Research 1989RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 211,77,1989
RTECS®- Mutation Research 1989RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 222,359,1989
RTECS®- Mutation Research 1991RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 260,349,1991
RTECS®- Mutation Research 1995RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 343,157,1995
RTECS®- Mutation Research 1989RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- -1964 211,77,1989
RTECS®- Mutation Research 1989RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- -1964 222,359,1989
RTECS®- Mutation Research 1991RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- -1964 260,349,1991
RTECS®- Mutation Research 1995RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- -1964 343,157,1995
RTECS®- National Technical Information Service RTECS®- National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. PB250-102
RTECS®- National Technical Information Service 4011RTECS®- National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. PB82-184011
RTECS®- National Toxicology Program Technical Report Series 1982RTECS®- National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- NTP-TR-217,1982
RTECS®- Nippon Eiseigaku Zasshi 1976RTECS®- Nippon Eiseigaku Zasshi. Japanese Journal of Hygiene. (Nippon Eisei Gakkai, c/o Kyoto Daigaku Igakubu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.1- 1946- 31,507,1976
RTECS®- Proceedings of the American Association for Cancer Research 1986RTECS®- Proceedings of the American Association for Cancer Research. (Waverly Press, 428 E. Preston St., Baltimore, MD 21202) V.1- 27,148,1986
RTECS®- Proceedings of the American Association for Cancer Research 1986RTECS®- Proceedings of the American Association for Cancer Research. (Waverly Press, 428 E. Preston St., Baltimore, MD 21202) V.1- 1954- 27,148,1986
RTECS®- Progress in Mutation Research 1985RTECS®- Progress in Mutation Research. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1981- 5,217,1985
RTECS®- Progress in Mutation Research 1985RTECS®- Progress in Mutation Research. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1981- 5,271,1985
RTECS®- Progress in Mutation Research 1985RTECS®- Progress in Mutation Research. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1981- 5,371,1985
RTECS®- Progress in Mutation Research 1985RTECS®- Progress in Mutation Research. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1981- 5,397,1985
RTECS®- Progress in Mutation Research 1985RTECS®- Progress in Mutation Research. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1981- 5,569,1985
RTECS®- Progress in Mutation Research 1985RTECS®- Progress in Mutation Research. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1981- 5,665,1985
RTECS®- Progress in Mutation Research 1985RTECS®- Progress in Mutation Research. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 5,217,1985
RTECS®- Progress in Mutation Research 1985RTECS®- Progress in Mutation Research. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 5,271,1985
RTECS®- Progress in Mutation Research 1985RTECS®- Progress in Mutation Research. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 5,371,1985
RTECS®- Progress in Mutation Research 1985RTECS®- Progress in Mutation Research. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 5,397,1985
RTECS®- Progress in Mutation Research 1985RTECS®- Progress in Mutation Research. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 5,569,1985
RTECS®- Progress in Mutation Research 1985RTECS®- Progress in Mutation Research. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 5,665,1985
RTECS®- Raw Material Data Handbook, Vol 1975RTECS®- Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. (National Assoc. of Printing Ink Research Institute, Francis McDonald Sinclair Memorial Laboratory, Lehigh Univ., Bethlehem, PA 18015) 2,32,1975
RTECS®- Science 1987RTECS®- Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- 236,933,1987
RTECS®- Science 1987RTECS®- Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 236,933,1987
RTECS®- Teratology, The International Journal of Abnormal Development 1987RTECS®- Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- 35,41,1987
RTECS®- Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv 1961RTECS®- Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- 2,59,1961
RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 1999RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V. 41, Jan. 1998- 50,195,1999
RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2000RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V. 41, Jan. 1998- 55,433,2000
RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2000RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V. 41, Jan. 1998- 58,377,2000
RTECS®- Toxicology and Applied Pharmacology 1973RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 26,253,1973
RTECS®- Toxicology and Applied Pharmacology 1974RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 29,35,1974
RTECS®- Toxicology and Applied Pharmacology 1978RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 45,230,1978
RTECS®- Toxicology and Applied Pharmacology 1981RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 61,205,1981
RTECS®- Toxicology and Applied Pharmacology 1985RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 77,116,1985
RTECS®- Toxicology and Applied Pharmacology 1988RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 96,494,1988
RTECS®- Toxicology and Applied Pharmacology 1974RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 29,35,1974
RTECS®- Toxicology and Applied Pharmacology 1988RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 96,494,1988
RTECS®- Toxicology Letters 1979RTECS®- Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- 4,113,1979
RTECS®- Toxicology Letters 1993RTECS®- Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- 66,317,1993
RTECS®- Veterinary and Human Toxicology 1995RTECS®- Veterinary and Human Toxicology. (American College of Veterinary and Comparative Toxicology, Publication Office, Comparative Toxicology, Manhattan, KS 66506) V.19- 1977- 37,310,1995

"RTECS®" is a United States trademark owned and licensed under authority of the U.S. Government, by and through MDL Information Systems, Inc.