The Power of Information

National Drinking Water Database


National Drinking Water Database - Chemical Contaminants

Chloroacetonitrile


Status: Unregulated - EPA has not established a maximum legal limit in tapwater for this contaminant.

Chloroacetonitrile is a synthetic chemical primarily used as an intermediate to produce insecticides and pharmaceuticals.

 
Detected
Found above
health guidelines
Found above
legal limit
States
1
-
-
Water utilities
1
-
-
People Served
320
-
-

Health Concerns for Chloroacetonitrile:


Chloroacetonitrile Exposure by State

Water utilities in 1 states have reported detecting Chloroacetonitrile in treated tap water since 2004, according to EWG's analysis of water quality data supplied by state water agencies.

StateWater Suppliers with Chloroacetonitrile contamination
SystemsPopulation
Texas1320
Total1320

The Most Polluted Communities

1 water utilities reported detecting Chloroacetonitrile in tap water since 2004, according to EWG's analysis of water quality data supplied by state water agencies

Ranked by highest average Chloroacetonitrile level

RankSystem Population Served Positive test results of total reported tests Average Level
(Range)
1City of Paint Rock
Paint Rock, TX
3201 of 11.7 ppb
(1.7 ppb)

Testing Summary for Chloroacetonitrile

Are tests routinely required for Chloroacetonitrile by federal law?No
Water suppliers reporting tests for Chloroacetonitrile (2004-2007):225 of 47,576
Average testing rate for water supplier reporting tests (2004-2007):1.1 per year

Occupational hazards

Type of concern: Reference:
Allowed workplace exposures restricted to low doses European Union - Classification & Labelling

Cancer

Type of concern: Reference:
One or more in vitro tests on mammalian cells show positive mutation results RTECS®- National Technical Information Service 6230
One or more in vitro tests on mammalian cells show positive mutation results RTECS®- Toxicologist 1993
One or more in vitro tests on mammalian cells show positive mutation results RTECS®- Fundamental and Applied Toxicology 1985
One or more in vitro tests on mammalian cells show positive mutation results RTECS®- Environmental and Molecular Mutagenesis 2000
Mutagen - limited evidence EPA Water Disinfection By-Products Carcinogenicity
One or more in vitro tests non-mammalian cells show positive mutation results RTECS®- Mutation Research 1995
One or more in vitro tests non-mammalian cells show positive mutation results RTECS®- Environmental and Molecular Mutagenesis 2000
One or more in vitro tests on microorganisms show positive mutation results RTECS®- Mutation Research 1995
Cancer - not classifiable/not likely to be human carcinogen Int'l Agency for Research on Cancer (IARC) - Carcinogens

Organ system toxicity (non-reproductive)

Type of concern: Reference:
One or more animal studies show sense organ effects at low doses RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J 1986
Classified as toxic or harmful European Union - Classification & Labelling

Ecotoxicology

Type of concern: Reference:
Wildlife and environmental toxicity European Union - Classification & Labelling

Irritation (skin, eyes, or lungs)

Type of concern: Reference:
One or more animal studies show skin irritation at moderate doses RTECS®- American Industrial Hygiene Association Journal 1962
One or more animal studies show skin irritation at moderate doses RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J 1986



Government, industry, academic studies and classifications

government/industry list/academic study appears on list as classification(s)
European Union - Classification & LabellingCHLOROACETONITRILE•Toxic
•Toxic by inhalation, skin contact, and ingestion
•Dangerous for the environment
•Toxic to aquatic organisms
EPA Water Disinfection By-Products CarcinogenicityCHLOROACETONITRILE•Low to moderate concern for potential carcinogenicity
Int'l Agency for Research on Cancer (IARC) - CarcinogensCHLOROACETONITRILE•IARC Group 3 (no cancer link)
RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J 1986CHLOROACETONITRILE• sense organ - Primary eye irritant (rabbit )
• skin - Primary skin irritant (rabbit )
RTECS®- American Industrial Hygiene Association Journal 1962CHLOROACETONITRILE• skin - Primary skin irritant (rabbit )
RTECS®- Environmental and Molecular Mutagenesis 2000CHLOROACETONITRILE• mutagenic - Positive mutation assay: Mutation in Micro-organism (Salmonella typhimurium )
• mutagenic - Positive mutation assay: DNA Damage ( human hla)
RTECS®- Fundamental and Applied Toxicology 1985CHLOROACETONITRILE• mutagenic - Positive mutation assay: Sister Chromatid Exchange (hamster ovr)
RTECS®- Mutation Research 1995CHLOROACETONITRILE• mutagenic - Positive mutation assay: Mutation in Micro-organism (Salmonella typhimurium )
• mutagenic - Positive mutation assay: Micronucleus test (non-mammalian species mul)
RTECS®- National Technical Information Service 6230CHLOROACETONITRILE• mutagenic - Positive mutation assay: DNA Damage ( human lym)
RTECS®- Toxicologist 1993CHLOROACETONITRILE• mutagenic - Positive mutation assay: Unscheduled DNA Synthesis (rat orl)



references

government/industry list/academic study reference
European Union - Classification & LabellingCPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
EPA Water Disinfection By-Products CarcinogenicityEPA (U.S. Environmental Protection Agency). 2006. EPA Water Disinfection By-Products with Carcinogenicity Estimates. Last updated: 10 April 2006.
Int'l Agency for Research on Cancer (IARC) - CarcinogensIARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures).
RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J 1986RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 -,907,1986
RTECS®- American Industrial Hygiene Association Journal 1962RTECS®- American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 23,95,1962
RTECS®- Environmental and Molecular Mutagenesis 2000RTECS®- Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 36,52,2000
RTECS®- Fundamental and Applied Toxicology 1985RTECS®- Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1-40, 1981-97. For publisher information, see TOSCF2 5,1065,1985
RTECS®- Mutation Research 1995RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 341,289,1995
RTECS®- National Technical Information Service 6230RTECS®- National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. PB84-246230
RTECS®- Toxicologist 1993RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- 13,220,1993

"RTECS®" is a United States trademark owned and licensed under authority of the U.S. Government, by and through MDL Information Systems, Inc.