National Drinking Water Database
National Drinking Water Database - Chemical Contaminants
Chloroacetonitrile
Status: Unregulated - EPA has not established a maximum legal limit in tapwater for this contaminant.
Chloroacetonitrile is a synthetic chemical primarily used as an intermediate to produce insecticides and pharmaceuticals.
Detected |
Found above health guidelines |
Found above legal limit |
|
|---|---|---|---|
| States | 1 |
- |
- |
| Water utilities | 1 |
- |
- |
| People Served | 320 |
- |
- |
Health Concerns for Chloroacetonitrile:
- Occupational hazards
- Cancer
- Organ system toxicity (non-reproductive)
- Ecotoxicology
- Irritation (skin, eyes, or lungs)
Chloroacetonitrile Exposure by State
Water utilities in 1 states have reported detecting Chloroacetonitrile in treated tap water since 2004, according to EWG's analysis of water quality data supplied by state water agencies.
| State | Water Suppliers with Chloroacetonitrile contamination | |
|---|---|---|
| Systems | Population | |
| Texas | 1 | 320 |
| Total | 1 | 320 |
The Most Polluted Communities
1 water utilities reported detecting Chloroacetonitrile in tap water since 2004, according to EWG's analysis of water quality data supplied by state water agencies
Ranked by highest average Chloroacetonitrile level
| Rank | System | Population Served | Positive test results of total reported tests | Average Level (Range) |
|---|---|---|---|---|
| 1 | City of Paint Rock Paint Rock, TX | 320 | 1 of 1 | 1.7 ppb (1.7 ppb) |
Testing Summary for Chloroacetonitrile
| Are tests routinely required for Chloroacetonitrile by federal law? | No |
| Water suppliers reporting tests for Chloroacetonitrile (2004-2007): | 225 of 47,576 |
| Average testing rate for water supplier reporting tests (2004-2007): | 1.1 per year |
Occupational hazards
| Type of concern: | Reference: |
| Allowed workplace exposures restricted to low doses | European Union - Classification & Labelling |
Cancer
| Type of concern: | Reference: |
| One or more in vitro tests on mammalian cells show positive mutation results | RTECS®- National Technical Information Service 6230 |
| One or more in vitro tests on mammalian cells show positive mutation results | RTECS®- Toxicologist 1993 |
| One or more in vitro tests on mammalian cells show positive mutation results | RTECS®- Fundamental and Applied Toxicology 1985 |
| One or more in vitro tests on mammalian cells show positive mutation results | RTECS®- Environmental and Molecular Mutagenesis 2000 |
| Mutagen - limited evidence | EPA Water Disinfection By-Products Carcinogenicity |
| One or more in vitro tests non-mammalian cells show positive mutation results | RTECS®- Mutation Research 1995 |
| One or more in vitro tests non-mammalian cells show positive mutation results | RTECS®- Environmental and Molecular Mutagenesis 2000 |
| One or more in vitro tests on microorganisms show positive mutation results | RTECS®- Mutation Research 1995 |
| Cancer - not classifiable/not likely to be human carcinogen | Int'l Agency for Research on Cancer (IARC) - Carcinogens |
Organ system toxicity (non-reproductive)
| Type of concern: | Reference: |
| One or more animal studies show sense organ effects at low doses | RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J 1986 |
| Classified as toxic or harmful | European Union - Classification & Labelling |
Ecotoxicology
| Type of concern: | Reference: |
| Wildlife and environmental toxicity | European Union - Classification & Labelling |
Irritation (skin, eyes, or lungs)
| Type of concern: | Reference: |
| One or more animal studies show skin irritation at moderate doses | RTECS®- American Industrial Hygiene Association Journal 1962 |
| One or more animal studies show skin irritation at moderate doses | RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J 1986 |
Government, industry, academic studies and classifications
| government/industry list/academic study | appears on list as | classification(s) |
| European Union - Classification & Labelling | CHLOROACETONITRILE | •Toxic •Toxic by inhalation, skin contact, and ingestion •Dangerous for the environment •Toxic to aquatic organisms |
| EPA Water Disinfection By-Products Carcinogenicity | CHLOROACETONITRILE | •Low to moderate concern for potential carcinogenicity |
| Int'l Agency for Research on Cancer (IARC) - Carcinogens | CHLOROACETONITRILE | •IARC Group 3 (no cancer link) |
| RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J 1986 | CHLOROACETONITRILE | • sense organ - Primary eye irritant (rabbit ) • skin - Primary skin irritant (rabbit ) |
| RTECS®- American Industrial Hygiene Association Journal 1962 | CHLOROACETONITRILE | • skin - Primary skin irritant (rabbit ) |
| RTECS®- Environmental and Molecular Mutagenesis 2000 | CHLOROACETONITRILE | • mutagenic - Positive mutation assay: Mutation in Micro-organism (Salmonella typhimurium ) • mutagenic - Positive mutation assay: DNA Damage ( human hla) |
| RTECS®- Fundamental and Applied Toxicology 1985 | CHLOROACETONITRILE | • mutagenic - Positive mutation assay: Sister Chromatid Exchange (hamster ovr) |
| RTECS®- Mutation Research 1995 | CHLOROACETONITRILE | • mutagenic - Positive mutation assay: Mutation in Micro-organism (Salmonella typhimurium ) • mutagenic - Positive mutation assay: Micronucleus test (non-mammalian species mul) |
| RTECS®- National Technical Information Service 6230 | CHLOROACETONITRILE | • mutagenic - Positive mutation assay: DNA Damage ( human lym) |
| RTECS®- Toxicologist 1993 | CHLOROACETONITRILE | • mutagenic - Positive mutation assay: Unscheduled DNA Synthesis (rat orl) |
references
| government/industry list/academic study | reference |
| European Union - Classification & Labelling | CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP. |
| EPA Water Disinfection By-Products Carcinogenicity | EPA (U.S. Environmental Protection Agency). 2006. EPA Water Disinfection By-Products with Carcinogenicity Estimates. Last updated: 10 April 2006. |
| Int'l Agency for Research on Cancer (IARC) - Carcinogens | IARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures). |
| RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J 1986 | RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 -,907,1986 |
| RTECS®- American Industrial Hygiene Association Journal 1962 | RTECS®- American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 23,95,1962 |
| RTECS®- Environmental and Molecular Mutagenesis 2000 | RTECS®- Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 36,52,2000 |
| RTECS®- Fundamental and Applied Toxicology 1985 | RTECS®- Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1-40, 1981-97. For publisher information, see TOSCF2 5,1065,1985 |
| RTECS®- Mutation Research 1995 | RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 341,289,1995 |
| RTECS®- National Technical Information Service 6230 | RTECS®- National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. PB84-246230 |
| RTECS®- Toxicologist 1993 | RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- 13,220,1993 |
"RTECS®" is a United States trademark owned and licensed under authority of the U.S. Government, by and through MDL Information Systems, Inc.
