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National Drinking Water Database - Chemical Contaminants

2,3,7,8-TCDD (Dioxin)

Status: Regulated - EPA has established a maximum legal limit in tapwater for this contaminant.

2,3,7,8-TCDD (Dioxin) is a carcinogenic pollutant from waste incineration and discharges from chemical factories. [read more]

Dioxin (Tetrachlorodibenzodioxin or 2,3,7,8ÐTCDD) Dioxins are contaminating byproducts of chemical manufacturing and burning (incineration) of products that contain chlorine. Dioxins cause cancer in humans, and they are generally considered to be among the most toxic environmental contaminants known to man. As a class, dioxins are extremely toxic, persistent, bioaccumulative, and lipophilic ("fat-loving"). This means that dioxins build up and are stored in fatty tissues and fluids, such as breast milk, and can be passed on to fetuses and infants during pregnancy and lactation. Most people are exposed to dioxins through the food they eat, primarily from meat, dairy, fish and eggs. In humans, dioxins are associated with cancer, skin lesions, damage to the nervous and immune systems, altered carbohydrate and lipid metabolism, thyroid disruption, altered menstrual cycling and cardiovascular effects (U.S. Environmental Protection Agency (USEPA) 2009b). In laboratory animals, dioxins are known to cause a variety of effects including cancer and impaired reproductive, endocrine, cardiovascular, immune, respiratory, neurological and metabolic functions. In addition, dioxins cause skin disease and birth defects. Annually, environmental releases of dioxin and dioxin compounds amount to hundreds of thousands of pounds (USEPA 2009i). The electric utility companies and chemical production industry account for the majority of these releases.

	Detected	Found above health guidelines	Found above legal limit
States	4	4	-
Water utilities	4	4	-
People Served	34,732	34,732	-

Health Concerns for 2,3,7,8-TCDD (Dioxin):

• Cancer
• Developmental/reproductive toxicity
• Endocrine disruption
• Organ system toxicity (non-reproductive)
• Persistence and bioaccumulation
• Allergies/immunotoxicity
• Neurotoxicity
• Biochemical or cellular level changes
• Irritation (skin, eyes, or lungs)
• Ecotoxicology

2,3,7,8-TCDD (Dioxin) Exposure by State

Water utilities in 4 states have reported detecting 2,3,7,8-TCDD (Dioxin) in treated tap water since 2004, according to EWG's analysis of water quality data supplied by state water agencies.

State	Water Suppliers with 2,3,7,8-TCDD (Dioxin) contamination		Water suppliers reporting 2,3,7,8-TCDD (Dioxin) above health-based limits
	Systems	Population	Systems	Population
California	1	25,909	1	25,909
Arizona	1	8,435	1	8,435
Idaho	1	253	1	253
Wisconsin	1	135	1	135
Total	4	34,732	4	34,732

The Most Polluted Communities

4 water utilities reported detecting 2,3,7,8-TCDD (Dioxin) in tap water since 2004, according to EWG's analysis of water quality data supplied by state water agencies

Ranked by highest average 2,3,7,8-TCDD (Dioxin) level

Rank	System	Population Served	Positive test results of total reported tests	Average Level (Range)
1	City of Stites Stites, ID	253	1 of 1	< 0.01 ppb (< .01 to 5.0E-6 ppb)
2	City of Norco Norco, CA	25,909	1 of 2	< 0.01 ppb (< .01 to 3.0E-6 ppb)
3	AZ Water Co-Miami,claypool Phoenix, AZ	8,435	1 of 8	< 0.01 ppb (< .01 to 5.0E-6 ppb)
4	S & S Cycle Lower Well Viola, WI	135	1 of 2	< 0.01 ppb (< .01 to 2.0E-6 ppb)

Health Based Limits for 2,3,7,8-TCDD (Dioxin)

Standard	Description	Level
Maximum Contaminant Limit Goal (MCLG)	A non-enforceable health goal that is set at a level at which no known or anticipated adverse effect on the health of persons occurs and which allows an adequate margin of safety. Source: U.S. Environmental Protection Agency.	0 ppb
EPA Human Health Water Quality Criteria	Water quality criteria set by the US EPA provide guidance for states and tribes authorized to establish water quality standards under the Clean Water Act (CWA) to protect human health. These are non-enforceable standards based upon exposure by both drinking water and the contribution of water contamination to other consumed foods. Source: U.S. Environmental Protection Agency.	0 ppb
One in one million (10-6) Cancer Risk	The concentration of a chemical in drinking water corresponding to an excess estimated lifetime cancer risk of 1 in 1,000,000. Source: U.S. Environmental Protection Agency.	0 ppb
One in ten thousand (10-4) Cancer Risk	The concentration of a chemical in drinking water corresponding to an excess estimated lifetime cancer risk of 1 in 10,000. Source: U.S. Environmental Protection Agency.	<0.01 ppb
Maximum Contaminant Limit (MCL)	The enforceable standard which defines the highest level of a contaminant that is allowed in drinking water. MCLs are set as close to health-based limits (Maximum Contaminant Level Goals, or MCLGs) as feasible using the best available analytical and treatment technologies and taking cost into consideration. Source: U.S. Environmental Protection Agency.	<0.01 ppb
Drinking Water Equivalent Level	A lifetime exposure concentration protective of adverse, noncarcinogenic health effects, that assumes all of the exposure to a contaminant is from drinking water. Source: U.S. Environmental Protection Agency.	<0.01 ppb
Children's health-based limit for 10-day exposure	Concentration of a chemical in drinking water that is not expected to cause any adverse, noncarcinogenic effects for up to ten days of exposure. The Ten-Day health-based limit (or Health Advisory, HA) is typically set to protect a 10-kg child consuming 1 liter of water per day. Source: U.S. Environmental Protection Agency.	<0.01 ppb
Children's health-based limit for 1-day exposure	Concentration of a chemical in drinking water that is not expected to cause any adverse, noncarcinogenic health effects for up to one day of exposure. The One-Day health-based limit (or Health Advisory, HA) is typically set to protect a 10-kg child consuming 1 liter of water per day. Source: U.S. Environmental Protection Agency.	<0.01 ppb

Testing Summary for 2,3,7,8-TCDD (Dioxin)

Are tests routinely required for 2,3,7,8-TCDD (Dioxin) by federal law?	Yes
Water suppliers reporting tests for 2,3,7,8-TCDD (Dioxin) (2004-2009):	2,089 of 47,576
Average testing rate for water supplier reporting tests (2004-2009):	0.4 per year

Violation Summary for 2,3,7,8-TCDD (Dioxin)

Data from the U.S. Environmental Protection Agency includes the following violations of federal standards for 2,3,7,8-TCDD (Dioxin) since 2004

Maximum Contaminant Level Exceedance Violations	0
Monitoring Violations	129
Reporting Violations	0

Cancer

Type of concern:	Reference:
Known human carcinogen	Int'l Agency for Research on Cancer (IARC) - Carcinogens
Known human carcinogen	NTP Report on Carcinogens, 11th Edition
Possible human carcinogen	California EPA Proposition 65
Cancer - strong evidence	Proposition 65 List of Carcinogens
One or more animal studies show tumor formation at very low doses	RTECS®- Toxicology and Applied Pharmacology 1988
One or more animal studies show tumor formation at very low doses	RTECS®- EHP, Environmental Health Perspectives 2001
One or more animal studies show tumor formation at very low doses	RTECS®- Carcinogenesis (London) 1994
One or more animal studies show tumor formation at very low doses	RTECS®- EHP, Environmental Health Perspectives 1997
One or more animal studies show tumor formation at very low doses	RTECS®- Toxicologist 2004
One or more animal studies show tumor formation at very low doses	RTECS®- National Toxicology Program Technical Report Series 1982
One or more animal studies show tumor formation at very low doses	RTECS®- National Cancer Institute Carcinogenesis Technical Report Series 1982
One or more animal studies show tumor formation at very low doses	RTECS®- Pesticide & Toxic Chemical News 1977
One or more animal studies show tumor formation at very low doses	RTECS®- Federation Proceedings, Federation of American Societies for Experimental Biology 1977
One or more animal studies show tumor formation at very low doses	RTECS®- Annals of the New York Academy of Sciences 1979
One or more animal studies show tumor formation at very low doses	RTECS®- Chemosphere 1977
One or more animal studies show tumor formation at very low doses	RTECS®- Nature 1979
One or more animal studies show tumor formation at very low doses	RTECS®- Bulletin of Environmental Contamination and Toxicology 1977
One or more animal studies show tumor formation at very low doses	RTECS®- National Technical Information Service 3684
One or more animal studies show tumor formation at very low doses	RTECS®- National Technical Information Service 3445
One or more animal studies show tumor formation at very low doses	RTECS®- Toxicology and Applied Pharmacology 2002
One or more animal studies show tumor formation at low doses	RTECS®- Toxicology and Applied Pharmacology 1990
One or more in vitro tests on mammalian cells show positive mutation results	RTECS®- Toxicologist 2005
One or more in vitro tests on mammalian cells show positive mutation results	RTECS®- Carcinogenesis (London) 1990
One or more in vitro tests on mammalian cells show positive mutation results	RTECS®- Toxicology and Applied Pharmacology 1985
One or more in vitro tests on mammalian cells show positive mutation results	RTECS®- Cancer Letters (Shannon, Ireland) 1988
One or more in vitro tests on mammalian cells show positive mutation results	RTECS®- Biochemical Pharmacology 1982
One or more in vitro tests on mammalian cells show positive mutation results	RTECS®- Toxicology 1983
One or more in vitro tests on mammalian cells show positive mutation results	RTECS®- Chemico-Biological Interactions 1974
One or more in vitro tests on mammalian cells show positive mutation results	RTECS®- Mutation Research 1978
One or more in vitro tests on mammalian cells show positive mutation results	RTECS®- Environmental Mutagenesis 1984
One or more in vitro tests on mammalian cells show positive mutation results	RTECS®- Journal of Biological Chemistry 1984
One or more in vitro tests on mammalian cells show positive mutation results	RTECS®- Carcinogenesis (London) 1987
One or more in vitro tests on mammalian cells show positive mutation results	RTECS®- Mutation Research 1977
One or more in vitro tests on mammalian cells show positive mutation results	RTECS®- Toxicology 1989
One or more in vitro tests on mammalian cells show positive mutation results	RTECS®- Toxicology and Applied Pharmacology 1974
One or more in vitro tests on mammalian cells show positive mutation results	RTECS®- Pergamon Series on Environmental Science 1982
One or more in vitro tests on mammalian cells show positive mutation results	RTECS®- Environmental Mutagenesis 1982
One or more in vitro tests on mammalian cells show positive mutation results	RTECS®- Chemosphere 1983
One or more in vitro tests on mammalian cells show positive mutation results	RTECS®- Environmental and Molecular Mutagenesis 2001
One or more in vitro tests on mammalian cells show positive mutation results	RTECS®- Chemosphere 1992
One or more in vitro tests on mammalian cells show positive mutation results	RTECS®- Chemical Research in Toxicology 2001
One or more in vitro tests on mammalian cells show positive mutation results	RTECS®- Japanese Journal of Toxicology and Environmental Health 2002
One or more in vitro tests on mammalian cells show positive mutation results	RTECS®- Toxicologist 2003
One or more in vitro tests on mammalian cells show positive mutation results	RTECS®- Toxicology Letters 2003
One or more in vitro tests on mammalian cells show positive mutation results	RTECS®- Toksikologicheskii Vestnik 1998
One or more in vitro tests on mammalian cells show positive mutation results	RTECS®- National Toxicology Program Technical Report Series 1982
One or more in vitro tests on mammalian cells show positive mutation results	RTECS®- Federation Proceedings, Federation of American Societies for Experimental Biology 1977
One or more in vitro tests on mammalian cells show positive mutation results	RTECS®- Chemosphere 1977
One or more in vitro tests on mammalian cells show positive mutation results	RTECS®- Nature 1979
One or more in vitro tests on mammalian cells show positive mutation results	RTECS®- National Technical Information Service 3445
One or more in vitro tests on mammalian cells show positive mutation results	RTECS®- EHP, Environmental Health Perspectives 1997
One or more in vitro tests on mammalian cells show positive mutation results	RTECS®- Mutation Research 2007
One or more in vitro tests on mammalian cells show positive mutation results	RTECS®- Biological and Pharmaceutical Bulletin 2006
One or more in vitro tests on mammalian cells show positive mutation results	RTECS®- Toxicology Letters 2007
One or more in vitro tests on mammalian cells show positive mutation results	RTECS®- Mutation Research 2004
One or more in vitro tests non-mammalian cells show positive mutation results	RTECS®- Ambio 1972
One or more in vitro tests non-mammalian cells show positive mutation results	RTECS®- Chemosphere 1983
One or more in vitro tests non-mammalian cells show positive mutation results	RTECS®- Pergamon Series on Environmental Science 1982
One or more animal studies show tumor formation at high doses	RTECS®- Toxicologist 2004

Developmental/reproductive toxicity

Type of concern:	Reference:
Human developmental toxicant - strong evidence	Proposition 65 List of Carcinogens
One or more animal studies show reproductive effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 1998
One or more animal studies show reproductive effects at very low doses	RTECS®- Toxicology 1994
One or more animal studies show reproductive effects at very low doses	RTECS®- Reproductive Toxicology 2001
One or more animal studies show reproductive effects at very low doses	RTECS®- Biology of Reproduction 1991
One or more animal studies show reproductive effects at very low doses	RTECS®- Journal of Pharmacology and Experimental Therapeutics 1980
One or more animal studies show reproductive effects at very low doses	RTECS®- Toxicology 1983
One or more animal studies show reproductive effects at very low doses	RTECS®- Toxicologist 2003
One or more animal studies show reproductive effects at very low doses	RTECS®- Biochemical Pharmacology 1982
One or more animal studies show reproductive effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 1990
One or more animal studies show reproductive effects at very low doses	RTECS®- Toxicology 1992
One or more animal studies show reproductive effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 1995
One or more animal studies show reproductive effects at very low doses	RTECS®- Toxicology Letters 1995
One or more animal studies show reproductive effects at very low doses	RTECS®- Biochemical Pharmacology 1990
One or more animal studies show reproductive effects at very low doses	RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2002
One or more animal studies show reproductive effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 2004
One or more animal studies show reproductive effects at very low doses	RTECS®- Toxicologist 2002
One or more animal studies show reproductive effects at very low doses	RTECS®- Toxicologist 2001
One or more animal studies show reproductive effects at very low doses	RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2000
One or more animal studies show reproductive effects at very low doses	RTECS®- Annals of the New York Academy of Sciences 1979
One or more animal studies show reproductive effects at very low doses	RTECS®- Veterinary and Human Toxicology 2001
One or more animal studies show reproductive effects at very low doses	RTECS®- Journal of Applied Toxicology (John Wiley & Sons, Ltd 2002
One or more animal studies show reproductive effects at very low doses	RTECS®- Archives of Toxicology 2003
One or more animal studies show reproductive effects at very low doses	RTECS®- Archives of Toxicology 2002
One or more animal studies show reproductive effects at very low doses	RTECS®- Teratology, The International Journal of Abnormal Development 1982
One or more animal studies show reproductive effects at very low doses	RTECS®- Food and Cosmetics Toxicology 1971
One or more animal studies show developmental effects at very low doses	RTECS®- Food and Cosmetics Toxicology 1971
One or more animal studies show developmental effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 1998
One or more animal studies show reproductive effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 1979
One or more animal studies show developmental effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 1979
One or more animal studies show reproductive effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 1996
One or more animal studies show reproductive effects at very low doses	RTECS®- Toxicology 1981
One or more animal studies show reproductive effects at very low doses	RTECS®- Biochemical Pharmacology 1977
One or more animal studies show reproductive effects at very low doses	RTECS®- Chemosphere 1992
One or more animal studies show reproductive effects at very low doses	RTECS®- EHP, Environmental Health Perspectives 1973
One or more animal studies show reproductive effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 1989
One or more animal studies show reproductive effects at very low doses	RTECS®- Drug and Chemical Toxicology 1979
One or more animal studies show reproductive effects at very low doses	RTECS®- International Journal of Immunopharmacology 1980
One or more animal studies show reproductive effects at very low doses	RTECS®- Teratology, The International Journal of Abnormal Development 1986
One or more animal studies show reproductive effects at very low doses	RTECS®- Teratology, The International Journal of Abnormal Development 1997
One or more animal studies show reproductive effects at very low doses	RTECS®- Archives of Toxicology, Supplement 1985
One or more animal studies show reproductive effects at very low doses	RTECS®- Bulletin of Environmental Contamination and Toxicology 1976
One or more animal studies show developmental effects at very low doses	RTECS®- Bulletin of Environmental Contamination and Toxicology 1976
One or more animal studies show reproductive effects at very low doses	RTECS®- Teratogenesis, Carcinogenesis, and Mutagenesis 1984
One or more animal studies show reproductive effects at very low doses	RTECS®- Molecular Pharmacology 1980
One or more animal studies show reproductive effects at very low doses	RTECS®- Neurotoxicology and Teratology 1989
One or more animal studies show reproductive effects at very low doses	RTECS®- Toxicologist 1983
One or more animal studies show reproductive effects at very low doses	RTECS®- Neurotoxicology and Teratology 1992
One or more animal studies show reproductive effects at very low doses	RTECS®- Biomedical and Environmental Sciences 2000
One or more animal studies show reproductive effects at very low doses	RTECS®- Environmental Research 1982
One or more animal studies show reproductive effects at very low doses	RTECS®- Chemosphere 1990
One or more animal studies show reproductive effects at very low doses	RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 1999
One or more animal studies show reproductive effects at very low doses	RTECS®- Biochemical Pharmacology 2001
One or more animal studies show reproductive effects at very low doses	RTECS®- Molecular Pharmacology 1989
One or more animal studies show reproductive effects at very low doses	RTECS®- Toxicologist 1993
One or more animal studies show reproductive effects at very low doses	RTECS®- Archives of Toxicology 1994
One or more animal studies show developmental effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 1995
One or more animal studies show reproductive effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 1997
One or more animal studies show reproductive effects at very low doses	RTECS®- Toxicologist 1994
One or more animal studies show reproductive effects at very low doses	RTECS®- Toxicologist 1990
One or more animal studies show reproductive effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 1994
One or more animal studies show developmental effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 1994
One or more animal studies show reproductive effects at very low doses	RTECS®- Biology of Reproduction 1996
One or more animal studies show developmental effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 1996
One or more animal studies show reproductive effects at very low doses	RTECS®- Toxicologist 1995
One or more animal studies show reproductive effects at very low doses	RTECS®- Teratology, The International Journal of Abnormal Development 1989
One or more animal studies show reproductive effects at very low doses	RTECS®- Environmental Toxicology and Pharmacology (Elsevier Science, P 2002
One or more animal studies show developmental effects at very low doses	RTECS®- Environmental Toxicology and Pharmacology (Elsevier Science, P 2002
One or more animal studies show reproductive effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 2001
One or more animal studies show reproductive effects at very low doses	RTECS®- Neurotoxicology and Teratology 2001
One or more animal studies show reproductive effects at very low doses	RTECS®- Handbook of pesticide toxicology 2001
One or more animal studies show reproductive effects at very low doses	RTECS®- Chemosphere 1989
One or more animal studies show reproductive effects at very low doses	RTECS®- Biochemical Pharmacology 1983
One or more animal studies show reproductive effects at very low doses	RTECS®- EHP, Environmental Health Perspectives 1997
One or more animal studies show reproductive effects at very low doses	RTECS®- Biology of Reproduction, Supplement 2000
One or more animal studies show developmental effects at very low doses	RTECS®- Biology of Reproduction, Supplement 2000
One or more animal studies show reproductive effects at very low doses	RTECS®- Archives of Toxicology 1993
One or more animal studies show reproductive effects at very low doses	RTECS®- Neurotoxicology and Teratology 2002
One or more animal studies show reproductive effects at very low doses	RTECS®- Teratology, The International Journal of Abnormal Development 1980
One or more animal studies show reproductive effects at very low doses	RTECS®- Teratogenesis, Carcinogenesis, and Mutagenesis 2000
One or more animal studies show reproductive effects at very low doses	RTECS®- JAT, Journal of Applied Toxicology 2002
One or more animal studies show reproductive effects at very low doses	RTECS®- Biochemical Pharmacology 2000
One or more animal studies show reproductive effects at very low doses	RTECS®- EHP, Environmental Health Perspectives 2002
One or more animal studies show developmental effects at very low doses	RTECS®- EHP, Environmental Health Perspectives 2002
One or more animal studies show reproductive effects at very low doses	RTECS®- Biology of Reproduction 2002
One or more animal studies show reproductive effects at very low doses	RTECS®- EHP, Environmental Health Perspectives 2001
One or more animal studies show reproductive effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 2002
One or more animal studies show reproductive effects at very low doses	RTECS®- Neurotoxicology 2003
One or more animal studies show developmental effects at very low doses	RTECS®- Neurotoxicology 2003
One or more animal studies show reproductive effects at very low doses	RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2003
One or more animal studies show developmental effects at very low doses	RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2003
One or more animal studies show reproductive effects at very low doses	RTECS®- Neurotoxicology and Teratology 2003
One or more animal studies show reproductive effects at very low doses	RTECS®- Reproductive Toxicology 2005
One or more animal studies show reproductive effects at very low doses	RTECS®- Toxicology 2004
One or more animal studies show reproductive effects at very low doses	RTECS®- Toxicologist 2005
One or more animal studies show developmental effects at very low doses	RTECS®- Toxicologist 2005
One or more animal studies show reproductive effects at very low doses	RTECS®- Toxicology Letters 2004
One or more animal studies show reproductive effects at very low doses	RTECS®- Toxicologist 2004
One or more animal studies show developmental effects at very low doses	RTECS®- Toxicologist 2001
One or more animal studies show developmental effects at very low doses	RTECS®- Toxicologist 2002
One or more animal studies show developmental effects at very low doses	RTECS®- Toxicologist 2004
One or more animal studies show reproductive effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 2005
One or more animal studies show developmental effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 2005
One or more animal studies show reproductive effects at very low doses	RTECS®- Reproductive Toxicology 2006
One or more animal studies show reproductive effects at low doses	RTECS®- Toxicology and Applied Pharmacology 1971
Limited evidence of reproductive toxicity	California EPA, Office of Environmental Health Hazard Assessment, 2003
One or more animal studies show reproductive effects at moderate doses	RTECS®- Chemosphere 1990
One or more animal studies show reproductive effects at moderate doses	RTECS®- Toxicology Letters 1995
One or more animal studies show reproductive effects at high doses	RTECS®- Archives of Toxicology, Supplement 1987
One or more animal studies show reproductive effects at high doses	RTECS®- Teratology, The International Journal of Abnormal Development 1991
One or more animal studies show reproductive effects at high doses	RTECS®- Toxicologist 2005

Endocrine disruption

Type of concern:	Reference:
Human endocrine disruptor - strong evidence	European Commission on Endocrine Disruption
One or more studies show endocrine system disruption at very low doses	RTECS®- Neurotoxicology and Teratology 1993
One or more studies show endocrine system disruption at very low doses	RTECS®- Toxicology 1996
One or more studies show endocrine system disruption at very low doses	RTECS®- Toxicology and Applied Pharmacology 1994
One or more studies show endocrine system disruption at very low doses	RTECS®- Toxicology and Applied Pharmacology 1997
One or more studies show endocrine system disruption at very low doses	RTECS®- Chemosphere 1989
One or more studies show endocrine system disruption at very low doses	RTECS®- Journal of Toxicology and Environmental Health 1985
One or more studies show endocrine system disruption at very low doses	RTECS®- Biology of Reproduction 1991
One or more studies show endocrine system disruption at very low doses	RTECS®- Toxicology and Applied Pharmacology 1990
One or more studies show endocrine system disruption at very low doses	RTECS®- Toxicology 1987
One or more studies show endocrine system disruption at very low doses	RTECS®- Toxicology and Applied Pharmacology 1986
One or more studies show endocrine system disruption at very low doses	RTECS®- Toxicology and Applied Pharmacology 1988
One or more studies show endocrine system disruption at very low doses	RTECS®- Biochemical Pharmacology 1986
One or more studies show endocrine system disruption at very low doses	RTECS®- Biochemical Pharmacology 1984
One or more studies show endocrine system disruption at very low doses	RTECS®- Archiv fuer Toxikologie 1983
One or more studies show endocrine system disruption at very low doses	RTECS®- Neurotoxicology 2002
One or more studies show endocrine system disruption at very low doses	RTECS®- Archives of Toxicology 1983
One or more studies show endocrine system disruption at very low doses	RTECS®- Chemosphere 1992
One or more studies show endocrine system disruption at very low doses	RTECS®- Biochemical and Biophysical Research Communications 1984
One or more studies show endocrine system disruption at very low doses	RTECS®- Biochemical and Biophysical Research Communications 1989
One or more studies show endocrine system disruption at very low doses	RTECS®- Toxicology 1992
One or more studies show endocrine system disruption at very low doses	RTECS®- Toxicology 1988
One or more studies show endocrine system disruption at very low doses	RTECS®- Toxicology and Applied Pharmacology 1995
One or more studies show endocrine system disruption at very low doses	RTECS®- Biochemical Pharmacology 1990
One or more studies show endocrine system disruption at very low doses	RTECS®- Journal of Developmental Physiology 1991
One or more studies show endocrine system disruption at very low doses	RTECS®- Environmental Toxicology and Chemistry 1997
One or more studies show endocrine system disruption at very low doses	RTECS®- Toxicology 1985
One or more studies show endocrine system disruption at very low doses	RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2002
One or more studies show endocrine system disruption at very low doses	RTECS®- Toxicology and Applied Pharmacology 2003
One or more studies show endocrine system disruption at very low doses	RTECS®- Toxicology and Applied Pharmacology 2002
One or more studies show endocrine system disruption at very low doses	RTECS®- Toxicology 2002
One or more studies show endocrine system disruption at very low doses	RTECS®- Toxicology Letters 2002
One or more studies show endocrine system disruption at very low doses	RTECS®- Toxicology 2004
One or more studies show endocrine system disruption at very low doses	RTECS®- Toxicology and Applied Pharmacology 2004
One or more studies show endocrine system disruption at very low doses	RTECS®- Toxicology Letters 2004
One or more studies show endocrine system disruption at very low doses	RTECS®- Toxicologist 2002
One or more studies show endocrine system disruption at very low doses	RTECS®- Toxicologist 2005
One or more studies show endocrine system disruption at very low doses	RTECS®- Toxicologist 2001
One or more studies show endocrine system disruption at very low doses	RTECS®- Toxicology and Applied Pharmacology 2005
One or more studies show endocrine system disruption at very low doses	RTECS®- Toxicology and Applied Pharmacology 1976
One or more studies show endocrine system disruption at very low doses	RTECS®- Toxicology and Applied Pharmacology 1992
One or more studies show endocrine system disruption at very low doses	RTECS®- EHP, Environmental Health Perspectives 1973
One or more studies show endocrine system disruption at very low doses	RTECS®- Toxicology and Applied Pharmacology 1974
One or more studies show endocrine system disruption at very low doses	RTECS®- Toxicology Letters 1992
One or more studies show endocrine system disruption at very low doses	RTECS®- Fundamental and Applied Toxicology 1986
One or more studies show endocrine system disruption at very low doses	RTECS®- European Journal of Pharmacology 1995
One or more studies show endocrine system disruption at very low doses	RTECS®- Chemosphere 1994
One or more studies show endocrine system disruption at very low doses	RTECS®- EHP, Environmental Health Perspectives 1995
One or more studies show endocrine system disruption at very low doses	RTECS®- European Journal of Pharmacology, Environmental Toxicology and Pharmacology Section 1995
One or more studies show endocrine system disruption at very low doses	RTECS®- Annals of the New York Academy of Sciences 1979
One or more studies show endocrine system disruption at very low doses	RTECS®- JAT, Journal of Applied Toxicology 2002
One or more studies show endocrine system disruption at very low doses	RTECS®- Journal of Applied Toxicology (John Wiley & Sons, Ltd 2002
One or more studies show endocrine system disruption at very low doses	RTECS®- Toxicologist 2003
One or more studies show endocrine system disruption at very low doses	RTECS®- Archives of Toxicology 2004
One or more studies show endocrine system disruption at very low doses	RTECS®- Toxicologist 2004
One or more studies show endocrine system disruption at very low doses	RTECS®- Reproductive Toxicology 2006
One or more studies show endocrine system disruption at very low doses	RTECS®- EHP, Environmental Health Perspectives 2002
One or more studies show endocrine system disruption at low doses	RTECS®- Biochemical Pharmacology 1987
Limited evidence of endocrine disruption	BKH/European Commission, 2000
endocrine - weight of evidence unknown/unassessed/unreview: published lit review or major tox study	Our Stolen Future Endocrine Disruptors

Organ system toxicity (non-reproductive)

Type of concern:	Reference:
Known human respiratory toxicant	EPA Hazardous Air Pollutants
One or more animal studies show broad systemic effects at very low doses	RTECS®- Experientia 1982
One or more animal studies show broad systemic effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 1978
One or more animal studies show sense organ effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 1974
One or more animal studies show cardiovascular effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 1974
One or more animal studies show gastrointestinal effects at very low doses	RTECS®- Research Communications in Chemical Pathology and Pharmacology 1978
One or more animal studies show broad systemic effects at very low doses	RTECS®- Scientific American 1986
One or more animal studies show liver effects at very low doses	RTECS®- Annals of the New York Academy of Sciences 1979
One or more animal studies show metabolic effects at very low doses	RTECS®- Annals of the New York Academy of Sciences 1979
One or more animal studies show broad systemic effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 1976
One or more animal studies show broad systemic effects at very low doses	RTECS®- EHP, Environmental Health Perspectives 1973
One or more animal studies show broad systemic effects at very low doses	RTECS®- Environmental Science Research 1973
One or more animal studies show gastrointestinal effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 1980
One or more animal studies show blood effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 1980
One or more animal studies show metabolic effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 1980
One or more animal studies show respiratory effects at very low doses	RTECS®- Food and Cosmetics Toxicology 1973
One or more animal studies show metabolic effects at very low doses	RTECS®- Food and Cosmetics Toxicology 1973
One or more animal studies show metabolic effects at very low doses	RTECS®- Journal of Toxicology and Environmental Health 1992
One or more animal studies show liver effects at very low doses	RTECS®- Archives of Environmental Contamination and Toxicology 1988
One or more animal studies show kidney or renal system effects at very low doses	RTECS®- Archives of Environmental Contamination and Toxicology 1988
One or more animal studies show blood effects at very low doses	RTECS®- Archives of Environmental Contamination and Toxicology 1988
One or more animal studies show metabolic effects at very low doses	RTECS®- Toxicology 1996
One or more animal studies show metabolic effects at very low doses	RTECS®- Toxicology 1994
One or more animal studies show liver effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 1995
One or more animal studies show metabolic effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 1995
One or more animal studies show blood effects at very low doses	RTECS®- Chemosphere 2001
One or more animal studies show liver effects at very low doses	RTECS®- Life Sciences 2001
One or more animal studies show metabolic effects at very low doses	RTECS®- Life Sciences 2001
One or more animal studies show cardiovascular effects at very low doses	RTECS®- Toxicology 2000
One or more animal studies show metabolic effects at very low doses	RTECS®- Toxicology 2000
One or more animal studies show metabolic effects at very low doses	RTECS®- Journal of Toxicology and Environmental Health 1985
One or more animal studies show metabolic effects at very low doses	RTECS®- Toxicology 1987
One or more animal studies show respiratory effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 1986
One or more animal studies show metabolic effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 1986
One or more animal studies show liver effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 1988
One or more animal studies show liver effects at very low doses	RTECS®- Biochemical Pharmacology 1986
One or more animal studies show metabolic effects at very low doses	RTECS®- Biochemical Pharmacology 1986
One or more animal studies show liver effects at very low doses	RTECS®- Archiv fuer Toxikologie 1983
One or more animal studies show broad systemic effects at very low doses	RTECS®- Environmental Health Criteria (United Nations Environment Programme
One or more animal studies show blood effects at very low doses	RTECS®- Environmental Health Criteria (United Nations Environment Programme 1998
One or more animal studies show liver effects at very low doses	RTECS®- Archives of Toxicology 1983
One or more animal studies show blood effects at very low doses	RTECS®- Archives of Toxicology 1983
One or more animal studies show liver effects at very low doses	RTECS®- Biochemical Pharmacology 1988
One or more animal studies show metabolic effects at very low doses	RTECS®- Biochemical Pharmacology 1988
One or more animal studies show liver effects at very low doses	RTECS®- Archives of Toxicology 1988
One or more animal studies show metabolic effects at very low doses	RTECS®- Lipids 1988
One or more animal studies show liver effects at very low doses	RTECS®- Lipids 1988
One or more animal studies show liver effects at very low doses	RTECS®- Journal of Pharmacology and Experimental Therapeutics 1989
One or more animal studies show blood effects at very low doses	RTECS®- Toxicology 1993
One or more animal studies show liver effects at very low doses	RTECS®- Toxicology 1993
One or more animal studies show blood effects at very low doses	RTECS®- Archives of Environmental Contamination and Toxicology 2001
One or more animal studies show liver effects at very low doses	RTECS®- Toxicologist 2003
One or more animal studies show blood effects at very low doses	RTECS®- Chemosphere 1992
One or more animal studies show metabolic effects at very low doses	RTECS®- Biochemical and Biophysical Research Communications 1984
One or more animal studies show metabolic effects at very low doses	RTECS®- Biochemical and Biophysical Research Communications 1989
One or more animal studies show metabolic effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 1990
One or more animal studies show metabolic effects at very low doses	RTECS®- Toxicology 1992
One or more animal studies show broad systemic effects at very low doses	RTECS®- Toxicology 1988
One or more animal studies show metabolic effects at very low doses	RTECS®- Canadian Journal of Physiology and Pharmacology 1985
One or more animal studies show metabolic effects at very low doses	RTECS®- Toxicology Letters 1995
One or more animal studies show liver effects at very low doses	RTECS®- Chemical Research in Toxicology 2000
One or more animal studies show kidney or renal system effects at very low doses	RTECS®- Chemical Research in Toxicology 2000
One or more animal studies show gastrointestinal effects at very low doses	RTECS®- EHP, Environmental Health Perspectives 2001
One or more animal studies show blood effects at very low doses	RTECS®- EHP, Environmental Health Perspectives 2001
One or more animal studies show liver effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 2003
One or more animal studies show respiratory effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 2003
One or more animal studies show blood effects at very low doses	RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2002
One or more animal studies show metabolic effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 2003
One or more animal studies show broad systemic effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 2003
One or more animal studies show blood effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 2002
One or more animal studies show metabolic effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 2002
One or more animal studies show liver effects at very low doses	RTECS®- Toxicologist
One or more animal studies show liver effects at very low doses	RTECS®- Toxicology 2002
One or more animal studies show metabolic effects at very low doses	RTECS®- Toxicology 2002
One or more animal studies show kidney or renal system effects at very low doses	RTECS®- Toxicologist
One or more animal studies show blood effects at very low doses	RTECS®- Toxicologist
One or more animal studies show blood effects at very low doses	RTECS®- Toxicology 2002
One or more animal studies show liver effects at very low doses	RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2003
One or more animal studies show blood effects at very low doses	RTECS®- Toxicology Letters 2002
One or more animal studies show blood effects at very low doses	RTECS®- Chemico-Biological Interactions 2003
One or more animal studies show kidney or renal system effects at very low doses	RTECS®- Chemico-Biological Interactions 2003
One or more animal studies show liver effects at very low doses	RTECS®- Chemico-Biological Interactions 2003
One or more animal studies show blood effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 2004
One or more animal studies show liver effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 2004
One or more animal studies show liver effects at very low doses	RTECS®- Toxicology 2004
One or more animal studies show metabolic effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 2004
One or more animal studies show liver effects at very low doses	RTECS®- Toxicologist 2005
One or more animal studies show blood effects at very low doses	RTECS®- Toxicology Letters 2004
One or more animal studies show metabolic effects at very low doses	RTECS®- Toxicology Letters 2004
One or more animal studies show liver effects at very low doses	RTECS®- Toxicologist 2004
One or more animal studies show blood effects at very low doses	RTECS®- Archives of Toxicology 2004
One or more animal studies show cardiovascular effects at very low doses	RTECS®- Archives of Toxicology 2002
One or more animal studies show metabolic effects at very low doses	RTECS®- Toxicologist 2002
One or more animal studies show blood effects at very low doses	RTECS®- Toxicologist 2002
One or more animal studies show blood effects at very low doses	RTECS®- Toxicologist 2001
One or more animal studies show broad systemic effects at very low doses	RTECS®- Toxicologist 2002
One or more animal studies show liver effects at very low doses	RTECS®- Toxicologist 2002
One or more animal studies show liver effects at very low doses	RTECS®- Toxicologist 2001
One or more animal studies show metabolic effects at very low doses	RTECS®- Toxicologist 2001
One or more animal studies show broad systemic effects at very low doses	RTECS®- Toxicologist 2001
One or more animal studies show liver effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 2005
One or more animal studies show blood effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 2005
One or more animal studies show respiratory effects at very low doses	RTECS®- Toxicology Letters 2005
One or more animal studies show blood effects at very low doses	RTECS®- Toxicology Letters 2005
One or more animal studies show gastrointestinal effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 2005
One or more animal studies show kidney or renal system effects at very low doses	RTECS®- Toxicologist 2001
One or more animal studies show respiratory effects at very low doses	RTECS®- Toxicologist 2001
One or more animal studies show broad systemic effects at very low doses	RTECS®- Toksikologicheskii Vestnik 1994
One or more animal studies show blood effects at very low doses	RTECS®- EHP, Environmental Health Perspectives 1973
One or more animal studies show liver effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 1976
One or more animal studies show blood effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 1976
One or more animal studies show liver effects at very low doses	RTECS®- Biochemical Pharmacology 1982
One or more animal studies show kidney or renal system effects at very low doses	RTECS®- Biochemical Pharmacology 1982
One or more animal studies show liver effects at very low doses	RTECS®- Bulletin of Environmental Contamination and Toxicology 1990
One or more animal studies show metabolic effects at very low doses	RTECS®- Bulletin of Environmental Contamination and Toxicology 1990
One or more animal studies show kidney or renal system effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 1981
One or more animal studies show liver effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 1992
One or more animal studies show liver effects at very low doses	RTECS®- National Toxicology Program Technical Report Series 1982
One or more animal studies show blood effects at very low doses	RTECS®- Journal of Environmental Pathology and Toxicology 1980
One or more animal studies show liver effects at very low doses	RTECS®- National Cancer Institute Carcinogenesis Technical Report Series
One or more animal studies show blood effects at very low doses	RTECS®- National Cancer Institute Carcinogenesis Technical Report Series
One or more animal studies show liver effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 1974
One or more animal studies show blood effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 1974
One or more animal studies show liver effects at very low doses	RTECS®- Toxicology Letters 1992
One or more animal studies show blood effects at very low doses	RTECS®- Toxicology Letters 1992
One or more animal studies show liver effects at very low doses	RTECS®- Chemosphere 1985
One or more animal studies show blood effects at very low doses	RTECS®- Chemosphere 1985
One or more animal studies show liver effects at very low doses	RTECS®- Chemosphere 1989
One or more animal studies show blood effects at very low doses	RTECS®- Chemosphere 1989
One or more animal studies show gastrointestinal effects at very low doses	RTECS®- Bulletin of Environmental Contamination and Toxicology 1977
One or more animal studies show metabolic effects at very low doses	RTECS®- Bulletin of Environmental Contamination and Toxicology 1977
One or more animal studies show liver effects at very low doses	RTECS®- Fundamental and Applied Toxicology 1986
One or more animal studies show metabolic effects at very low doses	RTECS®- Fundamental and Applied Toxicology 1986
One or more animal studies show metabolic effects at very low doses	RTECS®- EHP, Environmental Health Perspectives 1973
One or more animal studies show kidney or renal system effects at very low doses	RTECS®- EHP, Environmental Health Perspectives 1973
One or more animal studies show liver effects at very low doses	RTECS®- Bulletin of Environmental Contamination and Toxicology 1983
One or more animal studies show metabolic effects at very low doses	RTECS®- Chemosphere 1994
One or more animal studies show blood effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 1997
One or more animal studies show liver effects at very low doses	RTECS®- Teratology, The International Journal of Abnormal Development 1986
One or more animal studies show liver effects at very low doses	RTECS®- Chemosphere 2001
One or more animal studies show metabolic effects at very low doses	RTECS®- Chemosphere 2001
One or more animal studies show liver effects at very low doses	RTECS®- Chemosphere 1992
One or more animal studies show metabolic effects at very low doses	RTECS®- Chemosphere 1992
One or more animal studies show liver effects at very low doses	RTECS®- Carcinogenesis (London) 1994
One or more animal studies show metabolic effects at very low doses	RTECS®- Biochemical Pharmacology 1983
One or more animal studies show liver effects at very low doses	RTECS®- EHP, Environmental Health Perspectives 1997
One or more animal studies show metabolic effects at very low doses	RTECS®- Veterinary and Human Toxicology 2001
One or more animal studies show musculoskeletal effects at very low doses	RTECS®- Veterinary and Human Toxicology 2001
One or more animal studies show liver effects at very low doses	RTECS®- Veterinary and Human Toxicology 2001
One or more animal studies show blood effects at very low doses	RTECS®- Veterinary and Human Toxicology 2001
One or more animal studies show cardiovascular effects at very low doses	RTECS®- Toxicologist 2003
One or more animal studies show blood effects at very low doses	RTECS®- Toxicologist 2003
One or more animal studies show musculoskeletal effects at very low doses	RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2002
One or more animal studies show cardiovascular effects at very low doses	RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2002
One or more animal studies show metabolic effects at very low doses	RTECS®- Food and Chemical Toxicology 2004
One or more animal studies show liver effects at very low doses	RTECS®- Food and Chemical Toxicology 2004
One or more animal studies show cardiovascular effects at very low doses	RTECS®- Toxicologist 2005
One or more animal studies show respiratory effects at very low doses	RTECS®- Toxicologist 2004
One or more animal studies show respiratory effects at very low doses	RTECS®- Toxicologist 2002
One or more animal studies show gastrointestinal effects at very low doses	RTECS®- Toxicologist 2005
One or more animal studies show metabolic effects at very low doses	RTECS®- Toxicologist 2005
One or more animal studies show respiratory effects at very low doses	RTECS®- Toxicologist 2005
One or more animal studies show liver effects at low doses	RTECS®- Toxicology and Applied Pharmacology 2003
One or more animal studies show liver effects at low doses	RTECS®- Toxicology and Applied Pharmacology 1990
One or more animal studies show sense organ effects at low doses	RTECS®- EHP, Environmental Health Perspectives 1973
Limited evidence of cardiovascular or blood toxicity	Agency for Toxic Substances and Disease Registry, 2004
Limited evidence of sense organ toxicity	US EPA, Air Risk Information Support Center, 1996
Limited evidence of gastrointestinal or liver toxicity	US EPA, Air Risk Information Support Center, 1990
Limited evidence of kidney toxicity	Merck & Co
Limited evidence of respiratory toxicity	California EPA, Office of Environmental Health Hazard Assessment, 2003
One or more animal studies show liver effects at moderate doses (low dose studies may be unavailable for this ingredient)	RTECS®- Toxicologist 2005
One or more animal studies show metabolic effects at moderate doses (low dose studies may be unavailable for this ingredient)	RTECS®- Toxicologist 2005
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)	RTECS®- Toxicology and Applied Pharmacology 1978
One or more animal studies show kidney or renal system effects at high doses (low dose studies may be unavailable for this ingredient)	RTECS®- Toxicology and Applied Pharmacology 1978

Persistence and bioaccumulation

Type of concern:	Reference:
Persistent, bioaccumulative in wildlife and humans	United Nations Environment Programme/POPs Treaty
Persistent, bioaccumulative in wildlife and humans	EPA Toxic Release Inventory PBTs
Persistent, bioaccumulative in wildlife	Canada PBTs - Accelerated Reduction/Elimination of Toxics (ARET)
Persistent, bioaccumulative in wildlife	Great Lakes BTS (Binational Toxics Strategy) PBTs
Persistent, bioaccumulative in wildlife	OSPAR PBTs - Substances of Possible Concern
Persistent, bioaccumulative in wildlife	EPA PBTs - Waste Minimization Program (RCRA)

Allergies/immunotoxicity

Type of concern:	Reference:
Limited evidence of immune system toxicity or allergies	Agency for Toxic Substances and Disease Registry, 2004

Neurotoxicity

Type of concern:	Reference:
One or more animal studies show brain, nervous system, or behavioral effect effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 1974
One or more animal studies show brain, nervous system, or behavioral effect effects at very low doses	RTECS®- Journal of Toxicology and Environmental Health 1992
One or more animal studies show brain, nervous system, or behavioral effect effects at very low doses	RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2000
One or more animal studies show brain, nervous system, or behavioral effect effects at very low doses	RTECS®- Toxicology 1987
One or more animal studies show brain, nervous system, or behavioral effect effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 1986
One or more animal studies show brain, nervous system, or behavioral effect effects at very low doses	RTECS®- Archives of Toxicology 1988
One or more animal studies show brain, nervous system, or behavioral effect effects at very low doses	RTECS®- Toxicology 1988
One or more animal studies show brain, nervous system, or behavioral effect effects at very low doses	RTECS®- Toxicology 2002
One or more animal studies show brain, nervous system, or behavioral effect effects at very low doses	RTECS®- Toxicologist
One or more animal studies show brain, nervous system, or behavioral effect effects at very low doses	RTECS®- Toxicology and Applied Pharmacology 2004
One or more animal studies show brain, nervous system, or behavioral effect effects at very low doses	RTECS®- Toxicologist 2005
One or more animal studies show brain, nervous system, or behavioral effect effects at very low doses	RTECS®- Toxicologist 2004
One or more animal studies show brain, nervous system, or behavioral effect effects at very low doses	RTECS®- Toxicologist 2001
One or more animal studies show brain, nervous system, or behavioral effect effects at very low doses	RTECS®- Veterinary and Human Toxicology 2001
One or more animal studies show brain, nervous system, or behavioral effect effects at very low doses	RTECS®- Toxicologist 2003
One or more animal studies show brain, nervous system, or behavioral effect effects at very low doses	RTECS®- Japanese Journal of Toxicology and Environmental Health 2002
One or more animal studies show brain, nervous system, or behavioral effect effects at very low doses	RTECS®- Toxicologist 2002
One or more animal studies show brain, nervous system, or behavioral effect effects at low doses	RTECS®- Toxicologist 2001

Biochemical or cellular level changes

Type of concern:	Reference:
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Toxicology and Applied Pharmacology 1998
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Life Sciences 2001
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- EHP, Environmental Health Perspectives 1973
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Molecular Pharmacology 1977
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Biochemical Pharmacology 1986
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Journal of Pharmacology and Experimental Therapeutics 1980
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Toxicology 1983
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Archiv fuer Toxikologie 1983
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Archives of Toxicology 1983
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Biochemical Pharmacology 1988
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Neurotoxicology 2002
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Archives of Toxicology 1988
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Lipids 1988
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Journal of Pharmacology and Experimental Therapeutics 1989
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Toxicology 1993
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Archives of Environmental Contamination and Toxicology 2001
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Toxicologist 2003
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Biochemical Pharmacology 1982
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Chemosphere 1992
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Biochemical and Biophysical Research Communications 1984
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Toxicology 1990
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Canadian Journal of Physiology and Pharmacology 1985
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Chemical Research in Toxicology 2000
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Biochemical Pharmacology 1990
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Journal of Developmental Physiology 1991
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Environmental Toxicology and Chemistry 1997
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Toxicology 1985
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- EHP, Environmental Health Perspectives 2001
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Toxicology and Applied Pharmacology 2003
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Toxicology 2002
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Toxicologist
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Toxicology 2003
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2002
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Chemico-Biological Interactions 2003
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Toxicologist 2005
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Toxicology Letters 2004
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Toxicologist 2004
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Archives of Toxicology 2002
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Toxicologist 2002
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Toxicologist 2001
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Toxicology and Applied Pharmacology 2005
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Toxicology Letters 2005
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Bulletin of Environmental Contamination and Toxicology 1990
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Chemosphere 1985
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Bulletin of Environmental Contamination and Toxicology 1983
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Toxicology and Applied Pharmacology 1994
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Chemosphere 2001
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Carcinogenesis (London) 1994
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Biochemical Pharmacology 1983
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- EHP, Environmental Health Perspectives 1997
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- JAT, Journal of Applied Toxicology 2002
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Journal of Applied Toxicology (John Wiley & Sons, Ltd 2002
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Japanese Journal of Toxicology and Environmental Health 2002
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Food and Chemical Toxicology 2004
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Archives of Toxicology 2003
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Archives of Toxicology 2004
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood	RTECS®- Toksikologicheskii Vestnik 2003
One or more animal studies show biochemical changes at low doses where the human health implications are not yet well understood	RTECS®- Biochemical Pharmacology 1987
One or more animal studies show biochemical changes at low doses where the human health implications are not yet well understood	RTECS®- Toxicology and Applied Pharmacology 2003
One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood	RTECS®- Toxicologist 2005

Irritation (skin, eyes, or lungs)

Type of concern:	Reference:
One or more animal studies show skin irritation at very low doses	RTECS®- Scientific American 1986
One or more animal studies show skin irritation at very low doses	RTECS®- EHP, Environmental Health Perspectives 2001
One or more animal studies show skin irritation at very low doses	RTECS®- EHP, Environmental Health Perspectives 1995
One or more animal studies show skin irritation at low doses	RTECS®- Toxicology and Applied Pharmacology 1990
Limited evidence of skin irritation	National Library of Medicine HazMap
One or more animal studies show skin irritation at high doses	RTECS®- Toxicologist 2004

Ecotoxicology

Type of concern:	Reference:
Wildlife and environmental toxicity	EPA Clean Water Act - Priority Pollutants

Government, industry, academic studies and classifications

government/industry list/academic study	appears on list as	classification(s)
Association of Occupational and Environmental Clinics	CHLORINATED DIBENZODIOXINS	• P
Association of Occupational and Environmental Clinics	CHLORINATED DIBENZODIOXINS	• P
Canada - Prohibited and Restricted Cosmetics Ingredients	2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN	•Prohibited from use in Canadian cosmetics
EPA Clean Water Act - Priority Pollutants	2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN (TCDD)	•Priority water pollutant under the Clean Water Act
European Commission on Endocrine Disruption	2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN (2,3,7,8-TCDD)	HH-CAT1;
EPA Hazardous Air Pollutants	2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN	•Hazardous air pollutant under Clean Air Act
National Library of Medicine HazMap	2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN	•Dermatotoxin: Chloracne; •Restricted - Regulations that have banned or restricted the use of the agent: NIOSH recommends lowest feasible level of exposure. TCDD product contamination is limited to 0.01 to 0.05 ppm. For drinking water, MCL is 0.05 ppt. FDA limit for dioxins in fish is 25 ppt. [ATSDR Case Studies];HE: Hepatotoxin, Sec
Int'l Agency for Research on Cancer (IARC) - Carcinogens	2,3,7,8-TETRACHLORODIBENZO-PARA-DIOXIN	•IARC Group 1: carcinogenic to humans (International Agency for Research on Carcinogens)
NTP Report on Carcinogens, 11th Edition	2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN (TCDD)	•Known human carcinogen (National Toxicology Program classification)
Our Stolen Future Endocrine Disruptors	2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN	•
Aarhus Protocol on Persistent Organic Pollutants	2,3,7,8-TETRACHLORODIBENZO[B,E][1,4]DIOXIN	Obligates Parties to reduce emissions under Aahrus Protocol for Persistent Organic Pollutants
Canada PBTs - Accelerated Reduction/Elimination of Toxics (ARET)	2,3,7,8-TETRACHLORODIBENZO[B,E][1,4]DIOXIN	•Persistent, bioaccumulative toxicant under Canada's Accelerated Reduction/Elimination of Toxics program - targeted for elimination or reduction
Great Lakes BTS (Binational Toxics Strategy) PBTs	2,3,7,8-TETRACHLORODIBENZO[B,E][1,4]DIOXIN	•Persistent, bioaccumulative toxicant - Great Lakes Binational Strategy, Tier 1 concern (highest), targeted for phase-out
OSPAR PBTs - Substances of Possible Concern	2,3,7,8-TETRACHLORODIBENZO[B,E][1,4]DIOXIN	•Persistent, bioaccumulative toxicant - Oslo-Paris (OSPAR) Convention for the Protection of the Marine Environment of the North-East Atlantic, chemical of concern
EPA PBTs - Waste Minimization Program (RCRA)	DIBENZO(B,E)(1,4)DIOXIN, 2,3,7,8-TETRACHLORO-	•Persistent, bioaccumulative toxicant - Resource Conservation and Recovery Act, priority chemical for voluntary waste/emission reductions
United Nations Environment Programme/POPs Treaty	2,3,7,8-TETRACHLORODIBENZO[B,E][1,4]DIOXIN	•Persistent, bioaccumulative toxicant - targeted for emission reductions and process controls under international treaty (Stockholm Convention on Persistent Organic Pollutants, or POPs Convention)
EPA Toxic Release Inventory PBTs	2,3,7,8-TETRACHLORODIBENZO[B,E][1,4]DIOXIN	•Very persistent and bioaccumulative toxicant - targeted for waste reporting under U.S. Environmental Protection Agency Toxics Release Inventory programs
California EPA Proposition 65	2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN (TCDD)	•Carcinogen: California Proposition 65
Agency for Toxic Substances and Disease Registry, 2004	2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN (TCDD)	•Cardiovascular or blood toxicity hazards: suspected
Agency for Toxic Substances and Disease Registry, 2004	2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN (TCDD)	•Immunotoxicity hazards: suspected
BKH/European Commission, 2000	2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN (TCDD)	•Endocrine toxicity hazards: suspected
US EPA, Air Risk Information Support Center, 1996	2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN (TCDD)	•Skin or sense organ toxicity hazards: suspected
US EPA, Air Risk Information Support Center, 1990	2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN (TCDD)	•Gastrointestinal or liver toxicity hazards: suspected
Merck & Co	2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN (TCDD)	•Kidney toxicity hazards: suspected
California EPA, Office of Environmental Health Hazard Assessment, 2003	2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN (TCDD)	•Reproductive toxicity hazards: suspected
California EPA, Office of Environmental Health Hazard Assessment, 2003	2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN (TCDD)	•Respiratory toxicity hazards: suspected
Proposition 65 List of Carcinogens	2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN (TCDD)	•Developmental toxicity hazards: recognized
Proposition 65 List of Carcinogens	2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN (TCDD)	•Cancer hazards: recognized
RTECS®- Ambio 1972	DIOXINS	• mutagenic - Positive mutation assay: Mutation in Micro-organism (Escherichia coli ) • mutagenic - Positive mutation assay: Phage Inhibition Capacity (Escherichia coli )
RTECS®- Ambio 1972	DIOXINS	• mutagenic - Positive mutation assay: Mutation in Micro-organism (Salmonella typhimurium )
RTECS®- Ambio 1972	DIOXINS	• mutagenic - Positive mutation assay: Mutation in Micro-organism (Escherichia coli ) • mutagenic - Positive mutation assay: Phage Inhibition Capacity (Escherichia coli )
RTECS®- Ambio 1972	DIOXINS	• mutagenic - Positive mutation assay: Mutation in Micro-organism (Salmonella typhimurium )
RTECS®- Annals of the New York Academy of Sciences 1979	DIOXINS	• reproductive - Abortion (monkey TDLo) • reproductive - Female fertility index (monkey TDLo) • reproductive - Parturition (monkey TDLo) • reproductive - Post-implantation mortality (monkey TDLo) • endocrine system - Estrogenic (monkey TDLo) • endocrine system - Other changes (monkey TDLo)
RTECS®- Annals of the New York Academy of Sciences 1979	DIOXINS	• metabolic - Weight loss or decreased weight gain (mouse LDLo) • liver - Fatty liver degeneration (mouse LDLo)
RTECS®- Annals of the New York Academy of Sciences 1979	DIOXINS	• cancer - liver tumors (rat TD)
RTECS®- Archiv fuer Toxikologie 1983	DIOXINS	• endocrine system - Changes in spleen weight (rat TDLo) • liver - Other changes (rat TDLo) • biochemical - Other hydrolases (rat TDLo)
RTECS®- Archives of Environmental Contamination and Toxicology 1988	DIOXINS	• blood - Changes in spleen (mammal LD50) • kidney or renal system - Other changes (mammal LD50)
RTECS®- Archives of Environmental Contamination and Toxicology 2001	DIOXINS	• blood - Changes in bone marrow not included above (mouse TDLo) • biochemical - Effect on cyclic nucleotides (mouse TDLo)
RTECS®- Archives of Toxicology, Supplement 1987	DIOXINS	• reproductive - Prostate, seminal vesicle, Cowper's gland, accessory glands (rat TDLo) • reproductive - Testes, epididymis, sperm duct (rat TDLo)
RTECS®- Archives of Toxicology, Supplement 1985	DIOXINS	• reproductive - Craniofacial (mouse TDLo)
RTECS®- Archives of Toxicology 1983	DIOXINS	• blood - Changes in spleen (rat TDLo) • liver - Other changes (rat TDLo) • biochemical - Other hydrolases (rat TDLo)
RTECS®- Archives of Toxicology 1988	DIOXINS	• brain, nervous system, or behavioral effect - Food intake (animal) (rat TDLo) • biochemical - Lipids, including transport (rat TDLo) • liver - Other changes (rat TDLo)
RTECS®- Archives of Toxicology 1993	DIOXINS	• reproductive - Other effects on embryo (mouse TDLo)
RTECS®- Archives of Toxicology 1994	DIOXINS	• reproductive - Growth statistics (mouse TDLo) • reproductive - Urogenital system (mouse TDLo) • reproductive - Weaning or lactation index (mouse TDLo)
RTECS®- Archives of Toxicology 2002	DIOXINS	• reproductive - Spermatogenesis (rat TDLo) • reproductive - Testes, epididymis, sperm duct (rat TDLo) • biochemical - Multiple enzyme effects (rat TDLo)
RTECS®- Archives of Toxicology 2002	DIOXINS	• cardiovascular - Cardiomyopathy, including infarction (monkey TDLo) • biochemical - Other proteins (monkey TDLo)
RTECS®- Archives of Toxicology 2002	DIOXINS	• immune system - Decrease in cellular immune response (mouse TDLo)
RTECS®- Archives of Toxicology 2003	DIOXINS	• reproductive - Testes, epididymis, sperm duct (rat TDLo) • biochemical - Multiple enzyme effects (rat TDLo)
RTECS®- Archives of Toxicology 2004	DIOXINS	• blood - Changes in spleen (mouse TDLo) • immune system - Decrease in cellular immune response (mouse TDLo)
RTECS®- Archives of Toxicology 2004	DIOXINS	• endocrine system - Changes in uterine weight (mouse TDLo) • biochemical - Other oxidoreductases (mouse TDLo)
RTECS®- Biochemical and Biophysical Research Communications 1984	DIOXINS	• metabolic - Weight loss or decreased weight gain (rat LD50) • endocrine system - Changes in thymus weight (rat LD50) • biochemical - Other hydrolases (rat LD50)
RTECS®- Biochemical and Biophysical Research Communications 1989	DIOXINS	• metabolic - Weight loss or decreased weight gain (rat TDLo) • endocrine system - Changes in thymus weight (rat TDLo)
RTECS®- Biochemical Pharmacology 1977	DIOXINS	• reproductive - Biochemical and metabolic (rat TDLo)
RTECS®- Biochemical Pharmacology 1982	DIOXINS	• liver - Other changes (rat TDLo) • kidney or renal system - Other changes in urine composition (rat TDLo) • biochemical - Porphyrin, including bile pigments (rat TDLo)
RTECS®- Biochemical Pharmacology 1982	DIOXINS	• mutagenic - Positive mutation assay: Unscheduled DNA Synthesis (rat ivn)
RTECS®- Biochemical Pharmacology 1982	DIOXINS	• reproductive - Testes, epididymis, sperm duct (rat TDLo) • biochemical - Cytochrome oxidases (including oxidative phosphorylation) (rat TDLo)
RTECS®- Biochemical Pharmacology 1983	DIOXINS	• reproductive - Gastrointestinal system (rat TDLo) • metabolic - Weight loss or decreased weight gain (rat TDLo) • biochemical - Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (rat TDLo) • biochemical - Other (rat TDLo)
RTECS®- Biochemical Pharmacology 1984	DIOXINS	• endocrine system - Other changes (rat TDLo)
RTECS®- Biochemical Pharmacology 1986	DIOXINS	• metabolic - Weight loss or decreased weight gain (hamster TDLo) • liver - Changes in liver weight (hamster TDLo) • endocrine system - Changes in thymus weight (hamster TDLo) • biochemical - Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (hamster TDLo) • liver - Other changes (hamster TDLo)
RTECS®- Biochemical Pharmacology 1986	DIOXINS	• biochemical - Cytochrome oxidases (including oxidative phosphorylation) (rat TDLo) • biochemical - Other (rat TDLo) • endocrine system - Other changes (rat TDLo)
RTECS®- Biochemical Pharmacology 1988	DIOXINS	• metabolic - Weight loss or decreased weight gain (guinea pig TDLo) • biochemical - Multiple enzyme effects (guinea pig TDLo) • liver - Other changes (guinea pig TDLo)
RTECS®- Biochemical Pharmacology 1987	DIOXINS	• endocrine system - Androgenic (rat TDLo) • biochemical - Cytochrome oxidases (including oxidative phosphorylation) (rat TDLo) • biochemical - Other (rat TDLo)
RTECS®- Biochemical Pharmacology 1990	DIOXINS	• reproductive - Uterus, cervix, vagina (rat TDLo) • endocrine system - Changes in uterine weight (rat TDLo) • biochemical - Other oxidoreductases (rat TDLo)
RTECS®- Biochemical Pharmacology 2000	DIOXINS	• reproductive - Hepatobiliary system (rat TDLo)
RTECS®- Biochemical Pharmacology 2001	DIOXINS	• reproductive - Respiratory system (rat TDLo)
RTECS®- Biochemical Pharmacology 1982	DIOXINS	• mutagenic - Positive mutation assay: Unscheduled DNA Synthesis (rat ivn)
RTECS®- Biological and Pharmaceutical Bulletin 2006	DIOXINS	• mutagenic - Positive mutation assay: DNA Damage (mouse orl)
RTECS®- Biology of Reproduction, Supplement 2000	DIOXINS	• reproductive - Endocrine system (rat TDLo) • developmental - Physical (rat TDLo)
RTECS®- Biology of Reproduction 1991	DIOXINS	• reproductive - Testes, epididymis, sperm duct (rat TDLo) • endocrine system - Androgenic (rat TDLo) • endocrine system - Changes in LH (rat TDLo)
RTECS®- Biology of Reproduction 1996	DIOXINS	• reproductive - Endocrine system (rat TDLo)
RTECS®- Biology of Reproduction 2002	DIOXINS	• reproductive - Growth statistics (rat TDLo)
RTECS®- Biomedical and Environmental Sciences 2000	DIOXINS	• reproductive - Abortion (monkey TDLo)
RTECS®- Bulletin of Environmental Contamination and Toxicology 1976	DIOXINS	• reproductive - Craniofacial (mouse TDLo) • reproductive - Litter size (mouse TDLo) • developmental - Urogenital system (mouse TDLo)
RTECS®- Bulletin of Environmental Contamination and Toxicology 1977	DIOXINS	• metabolic - Other changes (monkey TDLo) • gastrointestinal - Ulceration or bleeding from stomach (monkey TDLo)
RTECS®- Bulletin of Environmental Contamination and Toxicology 1977	DIOXINS	• cancer - skin tumor formations - equivocal (mouse TD) • cancer - Tumors at site of application (mouse TD)
RTECS®- Bulletin of Environmental Contamination and Toxicology 1983	DIOXINS	• liver - Other changes (hamster TDLo) • biochemical - Other oxidoreductases (hamster TDLo) • biochemical - Other transferases (hamster TDLo)
RTECS®- Bulletin of Environmental Contamination and Toxicology 1990	DIOXINS	• metabolic - Fe (rat TDLo) • biochemical - Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (rat TDLo) • liver - Other changes (rat TDLo)
RTECS®- Canadian Journal of Physiology and Pharmacology 1985	DIOXINS	• metabolic - Weight loss or decreased weight gain (rat TDLo) • biochemical - Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (rat TDLo) • biochemical - Other (rat TDLo)
RTECS®- Cancer Letters (Shannon, Ireland) 1988	DIOXINS	• mutagenic - Positive mutation assay: DNA Damage (rat unr)
RTECS®- Cancer Letters (Shannon, Ireland) 1988	DIOXINS	• mutagenic - Positive mutation assay: DNA Damage (rat orl)
RTECS®- Cancer Letters (Shannon, Ireland) 1988	DIOXINS	• mutagenic - Positive mutation assay: DNA Damage (rat unr)
RTECS®- Cancer Letters (Shannon, Ireland) 1988	DIOXINS	• mutagenic - Positive mutation assay: DNA Damage (rat orl)
RTECS®- Carcinogenesis (London) 1990	DIOXINS	• mutagenic - Positive mutation assay: Unscheduled DNA Synthesis ( human oth)
RTECS®- Carcinogenesis (London) 1994	DIOXINS	• cancer - Cells (cultured) transformed (rat TDLo) • liver - Changes in liver weight (rat TDLo) • liver - Other changes (rat TDLo) • biochemical - Phosphatases (rat TDLo)
RTECS®- Carcinogenesis (London) 1987	DIOXINS	• mutagenic - Positive mutation assay: Unscheduled DNA Synthesis (mouse orl)
RTECS®- Carcinogenesis (London) 1990	DIOXINS	• mutagenic - Positive mutation assay: Unscheduled DNA Synthesis ( human oth)
RTECS®- Carcinogenesis (London) 1987	DIOXINS	• mutagenic - Positive mutation assay: Unscheduled DNA Synthesis (mouse orl)
RTECS®- Chemical Research in Toxicology 2001	DIOXINS	• mutagenic - Positive mutation assay: DNA Adduct (rat orl)
RTECS®- Chemical Research in Toxicology 2000	DIOXINS	• biochemical - Cytochrome oxidases (including oxidative phosphorylation) (rat TDLo) • kidney or renal system - Other changes (rat TDLo)
RTECS®- Chemical Research in Toxicology 2001	DIOXINS	• mutagenic - Positive mutation assay: DNA Adduct (rat orl)
RTECS®- Chemico-Biological Interactions 2003	DIOXINS	• blood - Changes in serum composition (eg., TP, bilirubin, cholesterol) (rat TDLo) • biochemical - Cytochrome oxidases (including oxidative phosphorylation) (rat TDLo) • biochemical - Other (rat TDLo) • liver - Other changes (rat TDLo) • biochemical - Other transferases (rat TDLo)
RTECS®- Chemico-Biological Interactions 1974	DIOXINS	• mutagenic - Positive mutation assay: DNA Inhibition (rat ipr)
RTECS®- Chemico-Biological Interactions 1974	DIOXINS	• mutagenic - Positive mutation assay: DNA Inhibition (rat ipr)
RTECS®- Chemosphere 1983	DIOXINS	• mutagenic - Positive mutation assay: Mutation in Micro-organism (Saccharomyces cerevisiae ) • mutagenic - Positive mutation assay: Gene Conversion and Mitotic Recombination (Saccharomyces cerevisiae ) • mutagenic - Positive mutation assay: Host-mediated Assay (mouse )
RTECS®- Chemosphere 1985	DIOXINS	• liver - Changes in liver weight (mouse TDLo) • blood - Changes in serum composition (eg., TP, bilirubin, cholesterol) (mouse TDLo) • biochemical - Transaminases (mouse TDLo)
RTECS®- Chemosphere 1989	DIOXINS	• reproductive - Endocrine system (rat TDLo) • reproductive - Hepatobiliary system (rat TDLo)
RTECS®- Chemosphere 1989	DIOXINS	• endocrine system - Estrogenic (rat TDLo) • endocrine system - Other changes (rat TDLo)
RTECS®- Chemosphere 1989	DIOXINS	• liver - Changes in liver weight (mouse TDLo) • blood - Changes in other cell count (unspecified) (mouse TDLo) • endocrine system - Changes in thymus weight (mouse TDLo)
RTECS®- Chemosphere 1990	DIOXINS	• reproductive - Behavioral (monkey TDLo)
RTECS®- Chemosphere 1990	DIOXINS	• reproductive - Fetal death (hamster TDLo)
RTECS®- Chemosphere 1992	DIOXINS	• reproductive - Immune and reticuloendothelial system (mouse TDLo) • blood - Changes in bone marrow not included above (mouse TDLo) • endocrine system - Other changes (mouse TDLo) • biochemical - Other transferases (mouse TDLo)
RTECS®- Chemosphere 1992	DIOXINS	• reproductive - Immune and reticuloendothelial system (mouse TDLo)
RTECS®- Chemosphere 1992	DIOXINS	• reproductive - Growth statistics (rat TDLo)
RTECS®- Chemosphere 1992	DIOXINS	• metabolic - Conditioned vitamin deficiency (rat TDLo) • endocrine system - Evidence of thyroid hypofunction (rat TDLo) • biochemical - Other (rat TDLo) • liver - Other changes (rat TDLo)
RTECS®- Chemosphere 1992	DIOXINS	• metabolic - Weight loss or decreased weight gain (rat TDLo) • liver - Changes in liver weight (rat TDLo) • endocrine system - Changes in thymus weight (rat TDLo) • biochemical - Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (rat TDLo)
RTECS®- Chemosphere 1992	DIOXINS	• mutagenic - Positive mutation assay: DNA Adduct (rat ipr)
RTECS®- Chemosphere 1994	DIOXINS	• metabolic - Weight loss or decreased weight gain (rat TDLo) • endocrine system - Changes in thymus weight (rat TDLo)
RTECS®- Chemosphere 2001	DIOXINS	• metabolic - Weight loss or decreased weight gain (rat TDLo) • liver - Changes in liver weight (rat TDLo) • biochemical - Lipids, including transport (rat TDLo) • blood - Microcytosis with or without anemia (rat TDLo) • biochemical - Multiple enzyme effects (rat TDLo) • liver - Other changes (rat TDLo)
RTECS®- Chemosphere 2001	DIOXINS	• blood - Changes in bone marrow not included above (mouse TDLo) • blood - Leukopenia (mouse TDLo)
RTECS®- Chemosphere 1977	DIOXINS	• mutagenic - liver tumor formations - equivocal (rat TD) • cancer - respiratory tumor formations - equivocal (rat TD)
RTECS®- Chemosphere 1977	DIOXINS	• mutagenic - liver tumors (rat TDLo) • cancer - respiratory tumors (rat TDLo)
RTECS®- Chemosphere 1983	DIOXINS	• mutagenic - Positive mutation assay: Mutation in Micro-organism (Saccharomyces cerevisiae ) • mutagenic - Positive mutation assay: Gene Conversion and Mitotic Recombination (Saccharomyces cerevisiae ) • mutagenic - Positive mutation assay: Host-mediated Assay (mouse )
RTECS®- Chemosphere 1992	DIOXINS	• mutagenic - Positive mutation assay: DNA Adduct (rat ipr)
RTECS®- Drug and Chemical Toxicology 1979	DIOXINS	• reproductive - Immune and reticuloendothelial system (mouse TDLo)
RTECS®- EHP, Environmental Health Perspectives 1973	DIOXINS	• sense organ - Primary eye irritant (rabbit )
RTECS®- EHP, Environmental Health Perspectives 1995	DIOXINS	• skin - Breast (rat TDLo) • endocrine system - Changes in ovarian weight (rat TDLo) • endocrine system - Changes in uterine weight (rat TDLo)
RTECS®- EHP, Environmental Health Perspectives 1997	DIOXINS	• reproductive - Ovaries, fallopian tubes (mouse TDLo) • reproductive - Uterus, cervix, vagina (mouse TDLo) • liver - Changes in liver weight (mouse TDLo) • biochemical - Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (mouse TDLo) • cancer - Increased incidence of tumors in susceptible strains (mouse TDLo) • mutagenic - reproductive (mouse TDLo)
RTECS®- EHP, Environmental Health Perspectives 2001	DIOXINS	• reproductive - Behavioral (rat TDLo)
RTECS®- EHP, Environmental Health Perspectives 2001	DIOXINS	• skin - Breast (rat TDLo) • cancer - Facilitates action of known carcinogen (rat TDLo) • cancer - skin (rat TDLo)
RTECS®- EHP, Environmental Health Perspectives 2001	DIOXINS	• skin - Dermatitis, other ( human TDLo) • biochemical - Lipids, including transport ( human TDLo) • gastrointestinal - Nausea or vomiting ( human TDLo) • blood - Normocytic anemia ( human TDLo)
RTECS®- EHP, Environmental Health Perspectives 2002	DIOXINS	• developmental - Biochemical and metabolic (rat TDLo) • reproductive - Central nervous system (rat TDLo)
RTECS®- EHP, Environmental Health Perspectives 2002	DIOXINS	• endocrine system - Differential effect of sex or castration on observed toxicity (rat TDLo)
RTECS®- EHP, Environmental Health Perspectives 1973	DIOXINS	• metabolic - Weight loss or decreased weight gain (guinea pig TDLo) • endocrine system - Changes in thymus weight (guinea pig TDLo)
RTECS®- EHP, Environmental Health Perspectives 1973	DIOXINS	• blood - Changes in platelet count (rat TDLo) • blood - Changes in serum composition (eg., TP, bilirubin, cholesterol) (rat TDLo) • biochemical - Multiple enzyme effects (rat TDLo)
RTECS®- EHP, Environmental Health Perspectives 1973	DIOXINS	• blood - Change in clotting factors (rat TDLo) • blood - Changes in erythrocyte (RBC) count (rat TDLo) • blood - Changes in platelet count (rat TDLo)
RTECS®- EHP, Environmental Health Perspectives 1973	DIOXINS	• endocrine system - Other changes (guinea pig TDLo)
RTECS®- EHP, Environmental Health Perspectives 1973	DIOXINS	• endocrine system - Changes in thymus weight (mouse TDLo) • immune system - Decrease in cellular immune response (mouse TDLo) • endocrine system - Other changes (mouse TDLo)
RTECS®- EHP, Environmental Health Perspectives 1973	DIOXINS	• biochemical - Cytochrome oxidases (including oxidative phosphorylation) (rat TDLo)
RTECS®- EHP, Environmental Health Perspectives 1973	DIOXINS	• reproductive - Urogenital system (mouse TDLo)
RTECS®- EHP, Environmental Health Perspectives 1973	DIOXINS	• broad systemic - Broad systemic toxicity (rabbit LD50) • sense organ - Primary eye irritant (rabbit )
RTECS®- Environmental and Molecular Mutagenesis 2001	DIOXINS	• mutagenic - Positive mutation assay: Morphological Transform (mouse fbr)
RTECS®- Environmental and Molecular Mutagenesis 2001	DIOXINS	• mutagenic - Positive mutation assay: Morphological Transform (mouse fbr)
RTECS®- Environmental Health Criteria (United Nations Environment Programme 1998	DIOXINS	• blood - Changes in leucocyte (WBC) count (monkey TDLo) • blood - Other changes (monkey TDLo)
RTECS®- Environmental Health Criteria (United Nations Environment Programme	DIOXINS	• broad systemic - Broad systemic toxicity (hamster LD50)
RTECS®- Environmental Mutagenesis 1982	DIOXINS	• mutagenic - Positive mutation assay: Mutation in Mammalian Somatic Cells (mouse lym)
RTECS®- Environmental Mutagenesis 1984	DIOXINS	• mutagenic - Positive mutation assay: Morphological Transform (mouse fbr)
RTECS®- Environmental Research 1982	DIOXINS	• reproductive - Abortion (rabbit TDLo) • reproductive - Musculoskeletal system (rabbit TDLo) • reproductive - Post-implantation mortality (rabbit TDLo) • reproductive - Pre-implantation mortality (rabbit TDLo)
RTECS®- Environmental Science Research 1973	DIOXINS	• broad systemic - Broad systemic toxicity (guinea pig LD50)
RTECS®- Environmental Toxicology and Chemistry 1997	DIOXINS	• endocrine system - Evidence of thyroid hyperfunction (wild bird species TDLo) • biochemical - Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (wild bird species TDLo)
RTECS®- Environmental Toxicology and Pharmacology (Elsevier Science, P 2002	DIOXINS	• developmental - Biochemical and metabolic (rat TDLo) • reproductive - Litter size (rat TDLo)
RTECS®- European Journal of Pharmacology, Environmental Toxicology and Pharmacology Section 1995	DIOXINS	• endocrine system - Changes in thymus weight (rat TDLo) • immune system - Decrease in cellular immune response (rat TDLo)
RTECS®- European Journal of Pharmacology 1995	DIOXINS	• endocrine system - Changes in thymus weight (rat TDLo) • immune system - Decrease in humoral immune response (rat TDLo)
RTECS®- Experientia 1982	DIOXINS	• broad systemic - Broad systemic toxicity (monkey LD50)
RTECS®- Federation Proceedings, Federation of American Societies for Experimental Biology 1977	DIOXINS	• mutagenic - kidney or renal system tumor formations - equivocal (rat TD) • cancer - liver tumor formations - equivocal (rat TD)
RTECS®- Food and Chemical Toxicology 2004	DIOXINS	• metabolic - Weight loss or decreased weight gain (mouse TDLo) • liver - Changes in liver weight (mouse TDLo) • biochemical - Effect on inflammation or mediation of inflammation (mouse TDLo) • liver - Fatty liver degeneration (mouse TDLo) • biochemical - Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (mouse TDLo) • biochemical - Lipids, including transport (mouse TDLo)
RTECS®- Food and Cosmetics Toxicology 1973	DIOXINS	• metabolic - Weight loss or decreased weight gain (chicken LDLo) • respiratory - Dyspnea (chicken LDLo)
RTECS®- Food and Cosmetics Toxicology 1971	DIOXINS	• reproductive - Fetal death (rat TDLo) • developmental - Other developmental abnormalities (rat TDLo)
RTECS®- Fundamental and Applied Toxicology 1986	DIOXINS	• metabolic - Weight loss or decreased weight gain (guinea pig TDLo) • liver - Changes in liver weight (guinea pig TDLo) • endocrine system - Changes in thymus weight (guinea pig TDLo)
RTECS®- Handbook of pesticide toxicology 2001	DIOXINS	• reproductive - Endocrine system (rat TDLo) • reproductive - Growth statistics (rat TDLo) • reproductive - Urogenital system (rat TDLo)
RTECS®- International Journal of Immunopharmacology 1980	DIOXINS	• reproductive - Growth statistics (mouse TDLo)
RTECS®- Japanese Journal of Toxicology and Environmental Health 2002	DIOXINS	• biochemical - Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (rat TDLo) • brain, nervous system, or behavioral effect - Other degenerative changes (rat TDLo) • mutagenic - Positive mutation assay: DNA Damage (rat orl)
RTECS®- Japanese Journal of Toxicology and Environmental Health 2002	DIOXINS	• mutagenic - Positive mutation assay: DNA Damage (rat orl)
RTECS®- JAT, Journal of Applied Toxicology 2002	DIOXINS	• reproductive - Prostate, seminal vesicle, Cowper's gland, accessory glands (rat TDLo) • reproductive - Spermatogenesis (rat TDLo) • reproductive - Testes, epididymis, sperm duct (rat TDLo) • endocrine system - Changes in prostate weight (rat TDLo) • endocrine system - Changes in testicular weight (rat TDLo) • biochemical - Multiple enzyme effects (rat TDLo)
RTECS®- Journal of Applied Toxicology (John Wiley & Sons, Ltd 2002	DIOXINS	• reproductive - Spermatogenesis (rat TDLo) • biochemical - Catalases (rat TDLo) • endocrine system - Changes in prostate weight (rat TDLo) • endocrine system - Changes in testicular weight (rat TDLo) • biochemical - Other enzymes (rat TDLo)
RTECS®- Journal of Biological Chemistry 1984	DIOXINS	• mutagenic - Positive mutation assay: other mutation test systems (mouse oth)
RTECS®- Journal of Biological Chemistry 1984	DIOXINS	• mutagenic - Positive mutation assay: other mutation test systems (mouse oth)
RTECS®- Journal of Developmental Physiology 1991	DIOXINS	• biochemical - Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (rat TDLo) • endocrine system - Other changes (rat TDLo)
RTECS®- Journal of Environmental Pathology and Toxicology 1980	DIOXINS	• blood - Changes in leucocyte (WBC) count (mouse TDLo) • immune system - Decrease in humoral immune response (mouse TDLo) • blood - Other changes (mouse TDLo)
RTECS®- Journal of Pharmacology and Experimental Therapeutics 1980	DIOXINS	• reproductive - Prostate, seminal vesicle, Cowper's gland, accessory glands (rat TDLo) • biochemical - Cytochrome oxidases (including oxidative phosphorylation) (rat TDLo)
RTECS®- Journal of Pharmacology and Experimental Therapeutics 1989	DIOXINS	• biochemical - Lipids, including transport (rat TDLo) • biochemical - Multiple enzyme effects (rat TDLo) • liver - Other changes (rat TDLo)
RTECS®- Journal of Toxicology and Environmental Health 1985	DIOXINS	• metabolic - Weight loss or decreased weight gain (rat TDLo) • endocrine system - Other changes (rat TDLo)
RTECS®- Journal of Toxicology and Environmental Health 1992	DIOXINS	• metabolic - Weight loss or decreased weight gain (chicken LDLo) • brain, nervous system, or behavioral effect - Food intake (animal) (chicken LDLo) • metabolic - Other changes (chicken LDLo)
RTECS®- Life Sciences 2001	DIOXINS	• metabolic - Fe (rat TDLo) • liver - Other changes (rat TDLo) • metabolic - Other metals (rat TDLo) • biochemical - Other proteins (rat TDLo)
RTECS®- Lipids 1988	DIOXINS	• metabolic - Weight loss or decreased weight gain (rat TDLo) • liver - Changes in liver weight (rat TDLo) • biochemical - Lipids, including transport (rat TDLo) • liver - Other changes (rat TDLo)
RTECS®- Molecular Pharmacology 1977	DIOXINS	• biochemical - Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (mouse TDLo)
RTECS®- Molecular Pharmacology 1980	DIOXINS	• reproductive - Craniofacial (mouse TDLo)
RTECS®- Molecular Pharmacology 1989	DIOXINS	• reproductive - Immune and reticuloendothelial system (mouse TDLo)
RTECS®- Mutation Research 1977	DIOXINS	• mutagenic - Positive mutation assay: DNA Inhibition (mouse ipr)
RTECS®- Mutation Research 1978	DIOXINS	• mutagenic - Positive mutation assay: Cytogenetic Analysis (rat ipr)
RTECS®- Mutation Research 2004	DIOXINS	• mutagenic - Positive mutation assay: DNA Damage (hamster ovr)
RTECS®- Mutation Research 2007	DIOXINS	• mutagenic - Positive mutation assay: other mutation test systems (rat lvr)
RTECS®- Mutation Research 1977	DIOXINS	• mutagenic - Positive mutation assay: DNA Inhibition (mouse ipr)
RTECS®- Mutation Research 1978	DIOXINS	• mutagenic - Positive mutation assay: Cytogenetic Analysis (rat ipr)
RTECS®- National Cancer Institute Carcinogenesis Technical Report Series 1982	DIOXINS	• cancer - skin tumors (mouse TDLo)
RTECS®- National Cancer Institute Carcinogenesis Technical Report Series	DIOXINS	• liver - Hepatitis (hepatocellular necrosis), diffuse (mouse TDLo) • blood - Changes in spleen (mouse TDLo)
RTECS®- National Technical Information Service 4117	DIOXINS	• immune system - Decrease in cellular immune response (rabbit TDLo) • immune system - Decrease in humoral immune response (rabbit TDLo)
RTECS®- National Technical Information Service 3445	DIOXINS	• cancer - endocrine system neoplasms (rat TDLo) • mutagenic - endocrine system tumors (mouse TDLo) • cancer - liver tumors (rat TDLo)
RTECS®- National Technical Information Service 3684	DIOXINS	• cancer - skin tumor formations - equivocal (mouse TDLo) • cancer - skin tumors (mouse TDLo)
RTECS®- National Toxicology Program Technical Report Series 1982	DIOXINS	• mutagenic - endocrine system tumor formations - equivocal (rat TD) • mutagenic - endocrine system tumors (rat TDLo) • cancer - liver tumor formations - equivocal (rat TD) • cancer - liver tumors (rat TDLo) • liver - Other changes (mouse TDLo)
RTECS®- Nature 1979	DIOXINS	• mutagenic - liver neoplasms (mouse TD) • cancer - respiratory neoplasms (mouse TD)
RTECS®- Neurotoxicology and Teratology 1989	DIOXINS	• reproductive - Behavioral (monkey TDLo)
RTECS®- Neurotoxicology and Teratology 1992	DIOXINS	• reproductive - Behavioral (monkey TDLo)
RTECS®- Neurotoxicology and Teratology 1993	DIOXINS	• endocrine system - Adrenal cortex hypoplasia (rat TDLo) • endocrine system - Other changes (rat TDLo)
RTECS®- Neurotoxicology and Teratology 2001	DIOXINS	• reproductive - Growth statistics (rat TDLo)
RTECS®- Neurotoxicology and Teratology 2002	DIOXINS	• reproductive - Behavioral (rat TDLo)
RTECS®- Neurotoxicology and Teratology 2003	DIOXINS	• reproductive - Behavioral (rat TDLo)
RTECS®- Neurotoxicology 2002	DIOXINS	• biochemical - Other (mouse TDLo) • endocrine system - Other changes (mouse TDLo) • biochemical - Other proteins (mouse TDLo)
RTECS®- Neurotoxicology 2003	DIOXINS	• developmental - Behavioral (rat TDLo) • reproductive - Central nervous system (rat TDLo)
RTECS®- Pergamon Series on Environmental Science 1982	DIOXINS	• mutagenic - Positive mutation assay: Cytogenetic Analysis (mouse ipr)
RTECS®- Pergamon Series on Environmental Science 1982	DIOXINS	• mutagenic - Positive mutation assay: Mutation in Micro-organism (Saccharomyces cerevisiae )
RTECS®- Pesticide & Toxic Chemical News 1977	DIOXINS	• cancer - respiratory tumor formations - equivocal (rat TD)
RTECS®- Reproductive Toxicology 2001	DIOXINS	• reproductive - Menstrual cycle changes or disorders (monkey TDLo) • reproductive - Ovaries, fallopian tubes (monkey TDLo)
RTECS®- Reproductive Toxicology 2005	DIOXINS	• reproductive - Craniofacial (monkey TDLo)
RTECS®- Reproductive Toxicology 2006	DIOXINS	• reproductive - Post-implantation mortality (mouse TDLo) • reproductive - Pre-implantation mortality (mouse TDLo) • reproductive - Testes, epididymis, sperm duct (mouse TDLo) • endocrine system - Changes in uterine weight (mouse TDLo) • endocrine system - Estrogenic (mouse TDLo)
RTECS®- Research Communications in Chemical Pathology and Pharmacology 1978	DIOXINS	• gastrointestinal - Other changes (mouse LDLo)
RTECS®- Scientific American 1986	DIOXINS	• broad systemic - Broad systemic toxicity (mouse LD50) • skin - Dermatitis, allergic ( human TDLo)
RTECS®- Teratogenesis, Carcinogenesis, and Mutagenesis 2000	DIOXINS	• reproductive - Cytological changes (mouse TDLo)
RTECS®- Teratogenesis, Carcinogenesis, and Mutagenesis 1984	DIOXINS	• reproductive - Craniofacial (mouse TDLo) • reproductive - Post-implantation mortality (mouse TDLo)
RTECS®- Teratology, The International Journal of Abnormal Development 1980	DIOXINS	• reproductive - Craniofacial (mouse TDLo)
RTECS®- Teratology, The International Journal of Abnormal Development 1982	DIOXINS	• reproductive - Fetotoxicity (rat TDLo)
RTECS®- Teratology, The International Journal of Abnormal Development 1986	DIOXINS	• reproductive - Post-implantation mortality (mouse TDLo) • liver - Changes in liver weight (mouse TDLo)
RTECS®- Teratology, The International Journal of Abnormal Development 1989	DIOXINS	• reproductive - Biochemical and metabolic (rat TDLo)
RTECS®- Teratology, The International Journal of Abnormal Development 1991	DIOXINS	• reproductive - Endocrine system (mouse TDLo)
RTECS®- Teratology, The International Journal of Abnormal Development 1997	DIOXINS	• reproductive - Cytological changes (rat TDLo)
RTECS®- Toksikologicheskii Vestnik 1998	DIOXINS	• mutagenic - Positive mutation assay: Cytogenetic Analysis (mouse lng)
RTECS®- Toksikologicheskii Vestnik 1994	DIOXINS	• broad systemic - Broad systemic toxicity (mouse LD50)
RTECS®- Toksikologicheskii Vestnik 1998	DIOXINS	• immune system - Decreased immune response (mouse TDLo)
RTECS®- Toksikologicheskii Vestnik 1998	DIOXINS	• mutagenic - Positive mutation assay: Cytogenetic Analysis (mouse lng)
RTECS®- Toksikologicheskii Vestnik 2003	DIOXINS	• biochemical - Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (rat TDLo)
RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 1999	DIOXINS	• reproductive - Growth statistics (hamster TDLo) • reproductive - Physical (hamster TDLo)
RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 1999	DIOXINS	• reproductive - Growth statistics (rat TDLo)
RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2000	DIOXINS	• brain, nervous system, or behavioral effect - Changes in motor activity (specific assay) (mouse TDLo)
RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2000	DIOXINS	• reproductive - Other effects (monkey TDLo) • immune system - Decreased immune response (monkey TDLo)
RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2002	DIOXINS	• endocrine system - Changes in spleen weight (mouse TDLo) • endocrine system - Changes in thymus weight (mouse TDLo) • immune system - Decrease in humoral immune response (mouse TDLo)
RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2002	DIOXINS	• reproductive - Uterus, cervix, vagina (mouse TDLo) • biochemical - Effect on cyclic nucleotides (mouse TDLo) • biochemical - Effect on inflammation or mediation of inflammation (mouse TDLo)
RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2002	DIOXINS	• reproductive - Fetotoxicity (mouse TDLo)
RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2002	DIOXINS	• reproductive - Urogenital system (mouse TDLo)
RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2002	DIOXINS	• biochemical - Effect on inflammation or mediation of inflammation (mouse TDLo) • biochemical - Lipids, including transport (mouse TDLo) • biochemical - Transaminases (mouse TDLo)
RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2002	DIOXINS	• blood - Changes in bone marrow not included above (mouse TDLo) • endocrine system - Changes in thymus weight (mouse TDLo)
RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2002	DIOXINS	• musculoskeletal - Changes in teeth and supporting structures (rat TDLo) • cardiovascular - Structural changes in vessels (rat TDLo)
RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2003	DIOXINS	• liver - Hepatitis (hepatocellular necrosis), zonal (rat TDLo) • liver - Other changes (rat TDLo)
RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2003	DIOXINS	• reproductive - Fetotoxicity (mouse TDLo) • developmental - Urogenital system (mouse TDLo)
RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2003	DIOXINS	• reproductive - Cytological changes (mouse TDLo)
RTECS®- Toxicologist 2001	DIOXINS	• reproductive - Other postnatal measures or effects (rat TDLo)
RTECS®- Toxicologist 2001	DIOXINS	• endocrine system - Changes in thymus weight (mouse TDLo) • endocrine system - Other changes (mouse TDLo)
RTECS®- Toxicologist 1990	DIOXINS	• reproductive - Spermatogenesis (rat TDLo) • reproductive - Testes, epididymis, sperm duct (rat TDLo) • reproductive - Urogenital system (rat TDLo)
RTECS®- Toxicologist 1993	DIOXINS	• reproductive - Cytological changes (mouse TDLo)
RTECS®- Toxicologist 1993	DIOXINS	• reproductive - Fetotoxicity (rat TDLo)
RTECS®- Toxicologist 1994	DIOXINS	• reproductive - Central nervous system (rat TDLo) • reproductive - Urogenital system (rat TDLo)
RTECS®- Toxicologist 1994	DIOXINS	• reproductive - Urogenital system (rat TDLo)
RTECS®- Toxicologist 1995	DIOXINS	• reproductive - Urogenital system (rat TDLo)
RTECS®- Toxicologist 1983	DIOXINS	• reproductive - Behavioral (monkey TDLo)
RTECS®- Toxicologist 2005	DIOXINS	• reproductive - Urogenital system (mouse TDLo)
RTECS®- Toxicologist 2005	DIOXINS	• reproductive - Urogenital system (mouse TDLo)
RTECS®- Toxicologist 2005	DIOXINS	• reproductive - Musculoskeletal system (rat TDLo) • reproductive - Other effects on embryo (mouse TDLo)
RTECS®- Toxicologist 2005	DIOXINS	• reproductive - Live birth index (rat TDLo) • reproductive - Other postnatal measures or effects (rat TDLo) • developmental - Physical (rat TDLo)
RTECS®- Toxicologist 2005	DIOXINS	• reproductive - Biochemical and metabolic (mouse TDLo)
RTECS®- Toxicologist 2005	DIOXINS	• reproductive - Cardiovascular (mouse TDLo)
RTECS®- Toxicologist 2005	DIOXINS	• cardiovascular - BP elevation not characterized in autonomic section (mouse TDLo)
RTECS®- Toxicologist 2005	DIOXINS	• reproductive - Immune and reticuloendothelial system (mouse TDLo)
RTECS®- Toxicologist 2005	DIOXINS	• biochemical - Other (mouse TDLo) • brain, nervous system, or behavioral effect - Other degenerative changes (mouse TDLo)
RTECS®- Toxicologist 2005	DIOXINS	• reproductive - Fetotoxicity (mouse TDLo)
RTECS®- Toxicologist 2005	DIOXINS	• biochemical - Other (mouse TDLo) • liver - Other changes (mouse TDLo)
RTECS®- Toxicologist 2005	DIOXINS	• gastrointestinal - Changes in structure or function of endocrine pancreas (rat TDLo) • biochemical - Other (rat TDLo)
RTECS®- Toxicologist 2005	DIOXINS	• metabolic - Fe (mouse TDLo) • liver - Liver function tests impaired (mouse TDLo) • biochemical - Other (mouse TDLo) • biochemical - Porphyrin, including bile pigments (mouse TDLo)
RTECS®- Toxicologist 2005	DIOXINS	• metabolic - Weight loss or decreased weight gain (rat TDLo) • mutagenic - biochemical (rat TDLo) • biochemical - Cytochrome oxidases (including oxidative phosphorylation) (rat TDLo) • biochemical - Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (rat TDLo) • biochemical - Other (rat TDLo) • respiratory - Other changes (rat TDLo) • brain, nervous system, or behavioral effect - Other degenerative changes (rat TDLo) • biochemical - Other enzymes (rat TDLo)
RTECS®- Toxicologist 2005	DIOXINS	• reproductive - Fetotoxicity (mouse TDLo) • brain, nervous system, or behavioral effect - Food intake (animal) (rat LDLo) • biochemical - Other (rat TDLo) • liver - Other changes (rat TDLo) • brain, nervous system, or behavioral effect - Other degenerative changes (rat TDLo)
RTECS®- Toxicologist 2005	DIOXINS	• reproductive - Urogenital system (rat TDLo)
RTECS®- Toxicologist 2001	DIOXINS	• biochemical - Other (rat TDLo) • liver - Other changes (rat TDLo) • biochemical - Other proteins (rat TDLo)
RTECS®- Toxicologist 2001	DIOXINS	• reproductive - Craniofacial (mouse TDLo) • developmental - Urogenital system (mouse TDLo) • liver - Changes in liver weight (mouse TDLo)
RTECS®- Toxicologist 2001	DIOXINS	• immune system - Decrease in cellular immune response (mouse TDLo) • biochemical - Other (mouse TDLo)
RTECS®- Toxicologist 2001	DIOXINS	• biochemical - Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (rat TDLo)
RTECS®- Toxicologist 2001	DIOXINS	• biochemical - Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (rat TDLo) • liver - Other changes (rat TDLo)
RTECS®- Toxicologist 2001	DIOXINS	• reproductive - Biochemical and metabolic (rat TDLo) • developmental - Delayed effects (rat TDLo)
RTECS®- Toxicologist 2001	DIOXINS	• reproductive - Uterus, cervix, vagina (mouse TDLo) • endocrine system - Changes in uterine weight (mouse TDLo)
RTECS®- Toxicologist 2001	DIOXINS	• blood - Changes in spleen (mouse TDLo) • immune system - Decrease in cellular immune response (mouse TDLo) • immune system - Decrease in humoral immune response (mouse TDLo)
RTECS®- Toxicologist 2001	DIOXINS	• metabolic - Weight loss or decreased weight gain (rat TDLo) • biochemical - Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (rat TDLo)
RTECS®- Toxicologist 2001	DIOXINS	• biochemical - Effect on mitochondrial function (mouse TDLo) • biochemical - Other (mouse TDLo) • liver - Other changes (mouse TDLo)
RTECS®- Toxicologist 2001	DIOXINS	• reproductive - Menstrual cycle changes or disorders (rat TDLo) • reproductive - Ovaries, fallopian tubes (rat TDLo) • reproductive - Urogenital system (rat TDLo) • endocrine system - Change in gonadotropins (rat TDLo) • endocrine system - Changes in LH (rat TDLo)
RTECS®- Toxicologist 2001	DIOXINS	• reproductive - Biochemical and metabolic (rat TDLo) • developmental - Delayed effects (rat TDLo) • reproductive - Physical (rat TDLo) • reproductive - Sex ratio (rat TDLo) • reproductive - Urogenital system (rat TDLo)
RTECS®- Toxicologist 2001	DIOXINS	• broad systemic - Broad systemic toxicity (rat LD50) • biochemical - Other (rat TDLo) • liver - Other changes (rat TDLo)
RTECS®- Toxicologist 2001	DIOXINS	• reproductive - Biochemical and metabolic (rat TDLo) • reproductive - Endocrine system (rat TDLo)
RTECS®- Toxicologist 2001	DIOXINS	• reproductive - Urogenital system (mouse TDLo)
RTECS®- Toxicologist 2001	DIOXINS	• reproductive - Behavioral (mouse TDLo) • biochemical - Cytochrome oxidases (including oxidative phosphorylation) (chicken TDLo) • biochemical - Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (chicken TDLo) • kidney or renal system - Other changes (chicken TDLo)
RTECS®- Toxicologist 2001	DIOXINS	• broad systemic - Broad systemic toxicity (chicken TDLo) • brain, nervous system, or behavioral effect - Coma (chicken TDLo) • metabolic - Metabolic acidosis (chicken TDLo) • respiratory - Respiratory depression (chicken TDLo)
RTECS®- Toxicologist 2001	DIOXINS	• brain, nervous system, or behavioral effect - Anti-convulsant (mouse TDLo)
RTECS®- Toxicologist 2001	DIOXINS	• reproductive - Other postnatal measures or effects (rat TDLo) • brain, nervous system, or behavioral effect - Convulsions or effect on seizure threshold (rat TDLo)
RTECS®- Toxicologist 2002	DIOXINS	• reproductive - Central nervous system (rat TDLo) • reproductive - Other developmental abnormalities (mouse TDLo)
RTECS®- Toxicologist 2002	DIOXINS	• liver - Other changes (rat TDLo)
RTECS®- Toxicologist 2002	DIOXINS	• reproductive - Central nervous system (rat TDLo) • reproductive - Fetotoxicity (mouse TDLo) • reproductive - Other developmental abnormalities (rat TDLo) • liver - Other changes (rat TDLo) • brain, nervous system, or behavioral effect - Other degenerative changes (rat TDLo)
RTECS®- Toxicologist 2002	DIOXINS	• reproductive - Fetotoxicity (mouse TDLo) • biochemical - Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (rat TDLo)
RTECS®- Toxicologist 2002	DIOXINS	• reproductive - Blood and lymphatic system (rat TDLo) • reproductive - Prostate, seminal vesicle, Cowper's gland, accessory glands (rat TDLo) • reproductive - Testes, epididymis, sperm duct (rat TDLo) • metabolic - Weight loss or decreased weight gain (rat TDLo) • endocrine system - Androgenic (rat TDLo) • endocrine system - Changes in prostate weight (rat TDLo) • biochemical - Cytochrome oxidases (including oxidative phosphorylation) (rat TDLo) • biochemical - Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (rat TDLo) • respiratory - Other changes (rat TDLo)
RTECS®- Toxicologist 2002	DIOXINS	• blood - Changes in spleen (mouse TDLo) • immune system - Decrease in humoral immune response (mouse TDLo)
RTECS®- Toxicologist 2002	DIOXINS	• endocrine system - Changes in spleen weight (mouse TDLo) • endocrine system - Changes in thymus weight (mouse TDLo)
RTECS®- Toxicologist 2002	DIOXINS	• reproductive - Central nervous system (mouse TDLo) • developmental - Urogenital system (mouse TDLo)
RTECS®- Toxicologist 2002	DIOXINS	• reproductive - Other developmental abnormalities (rat TDLo)
RTECS®- Toxicologist 2002	DIOXINS	• broad systemic - Broad systemic toxicity (rat LD25) • blood - Changes in spleen (mouse TDLo) • endocrine system - Changes in thymus weight (mouse TDLo) • endocrine system - Other changes (mouse TDLo)
RTECS®- Toxicologist 2002	DIOXINS	• endocrine system - Changes in LH (rat TDLo) • blood - Changes in serum composition (eg., TP, bilirubin, cholesterol) (rat TDLo)
RTECS®- Toxicologist 2002	DIOXINS	• endocrine system - Other changes (rat TDLo)
RTECS®- Toxicologist 2002	DIOXINS	• respiratory - Other changes (rat TDLo)
RTECS®- Toxicologist	DIOXINS	• liver - Changes in liver weight (mouse TDLo) • immune system - Decrease in cellular immune response (mouse TDLo) • liver - Fatty liver degeneration (mouse TDLo) • biochemical - Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (mouse TDLo) • blood - Other changes (mouse TDLo) • kidney or renal system - Other changes in urine composition (mouse TDLo) • brain, nervous system, or behavioral effect - Other degenerative changes (rat TDLo)
RTECS®- Toxicologist 2003	DIOXINS	• reproductive - Cytological changes (mouse TDLo)
RTECS®- Toxicologist 2003	DIOXINS	• reproductive - Central nervous system (mouse TDLo)
RTECS®- Toxicologist 2003	DIOXINS	• reproductive - Fetotoxicity (mouse TDLo)
RTECS®- Toxicologist 2003	DIOXINS	• biochemical - Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (mouse TDLo) • liver - Other changes (mouse TDLo) • biochemical - Other enzymes (mouse TDLo)
RTECS®- Toxicologist 2003	DIOXINS	• reproductive - Fetotoxicity (mouse TDLo)
RTECS®- Toxicologist 2003	DIOXINS	• reproductive - Breasts, lactation (mouse TDLo) • reproductive - Immune and reticuloendothelial system (mouse TDLo) • reproductive - Viability index (mouse TDLo)
RTECS®- Toxicologist 2003	DIOXINS	• reproductive - Central nervous system (rat TDLo)
RTECS®- Toxicologist 2003	DIOXINS	• reproductive - Breasts, lactation (mouse TDLo) • blood - Changes in serum composition (eg., TP, bilirubin, cholesterol) (mouse TDLo)
RTECS®- Toxicologist 2003	DIOXINS	• liver - Other changes (rat TDLo)
RTECS®- Toxicologist 2003	DIOXINS	• cardiovascular - Cardiomyopathy, including infarction (rat TDLo) • liver - Other changes (rat TDLo) • cardiovascular - Structural changes in vessels (rat TDLo)
RTECS®- Toxicologist 2003	DIOXINS	• biochemical - Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (rat TDLo) • liver - Other changes (rat TDLo) • biochemical - Other proteins (rat TDLo)
RTECS®- Toxicologist 2003	DIOXINS	• reproductive - Spermatogenesis (rat TDLo) • endocrine system - Changes in prostate weight (rat TDLo) • endocrine system - Changes in testicular weight (rat TDLo)
RTECS®- Toxicologist 2003	DIOXINS	• mutagenic - Positive mutation assay: Gene Conversion and Mitotic Recombination (hamster ovr)
RTECS®- Toxicologist 2003	DIOXINS	• reproductive - Spermatogenesis (mouse TDLo) • reproductive - Testes, epididymis, sperm duct (mouse TDLo)
RTECS®- Toxicologist 2003	DIOXINS	• brain, nervous system, or behavioral effect - Other degenerative changes (rat TDLo) • brain, nervous system, or behavioral effect - Recordings from specific areas of CNS (rat TDLo)
RTECS®- Toxicologist 2004	DIOXINS	• liver - Other changes (mouse TDLo) • brain, nervous system, or behavioral effect - Other degenerative changes (mouse TDLo) • biochemical - Other proteins (mouse TDLo)
RTECS®- Toxicologist 2004	DIOXINS	• reproductive - Urogenital system (mouse TDLo)
RTECS®- Toxicologist 2004	DIOXINS	• biochemical - Cytochrome oxidases (including oxidative phosphorylation) (rat TDLo) • immune system - Decrease in cellular immune response (mouse TDLo) • cancer - liver (rat TDLo) • liver - Multiple effects (rat TDLo) • liver - Other changes (rat TDLo) • biochemical - Other proteins (rat TDLo) • respiratory - Tumors (rat TDLo)
RTECS®- Toxicologist 2004	DIOXINS	• reproductive - Breasts, lactation (mouse TDLo) • reproductive - Other effects (mouse TDLo) • reproductive - Viability index (mouse TDLo)
RTECS®- Toxicologist 2004	DIOXINS	• endocrine system - Changes in thymus weight (rat TDLo) • liver - Other changes (rat TDLo)
RTECS®- Toxicologist 2004	DIOXINS	• endocrine system - Differential effect of sex or castration on observed toxicity (rat TDLo) • liver - Other changes (rat TDLo) • biochemical - Other proteins (rat TDLo)
RTECS®- Toxicologist 2004	DIOXINS	• biochemical - Lipids, including transport (rat TDLo) • biochemical - Multiple enzyme effects (rat TDLo) • liver - Other changes (mouse TDLo) • brain, nervous system, or behavioral effect - Other degenerative changes (rat TDLo) • biochemical - Other proteins (mouse TDLo)
RTECS®- Toxicologist 2004	DIOXINS	• reproductive - Urogenital system (mouse TDLo)
RTECS®- Toxicologist 2004	DIOXINS	• cancer - Increased incidence of tumors in susceptible strains (mouse TDLo) • skin - Tumors (mouse TDLo)
RTECS®- Toxicologist 2004	DIOXINS	• developmental - Behavioral (rat TDLo) • reproductive - Central nervous system (rat TDLo)
RTECS®- Toxicologist 2004	DIOXINS	• reproductive - Immune and reticuloendothelial system (mouse TDLo)
RTECS®- Toxicologist 2003	DIOXINS	• mutagenic - Positive mutation assay: Gene Conversion and Mitotic Recombination (hamster ovr)
RTECS®- Toxicology and Applied Pharmacology 1990	DIOXINS	• liver - Changes in liver weight (mouse TDLo) • skin - Dermatitis, other (mouse TDLo) • cancer - Facilitates action of known carcinogen (mouse TDLo)
RTECS®- Toxicology and Applied Pharmacology 1990	DIOXINS	• endocrine system - Androgenic (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 1990	DIOXINS	• reproductive - Prostate, seminal vesicle, Cowper's gland, accessory glands (rat TDLo) • metabolic - Weight loss or decreased weight gain (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 1992	DIOXINS	• liver - Changes in liver weight (mouse TDLo) • endocrine system - Changes in spleen weight (mouse TDLo) • endocrine system - Changes in thymus weight (mouse TDLo)
RTECS®- Toxicology and Applied Pharmacology 1994	DIOXINS	• biochemical - Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (mouse TDLo) • biochemical - Plasma proteins not involving coagulation (mouse TDLo)
RTECS®- Toxicology and Applied Pharmacology 1994	DIOXINS	• developmental - Growth statistics (rat TDLo) • reproductive - Spermatogenesis (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 1994	DIOXINS	• reproductive - Fetotoxicity (rat TDLo) • developmental - Urogenital system (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 1994	DIOXINS	• endocrine system - Changes in thymus weight (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 1995	DIOXINS	• reproductive - Urogenital system (hamster TDLo)
RTECS®- Toxicology and Applied Pharmacology 1995	DIOXINS	• reproductive - Endocrine system (rat TDLo) • developmental - Growth statistics (rat TDLo) • reproductive - Other measures of fertility (rat TDLo) • developmental - Urogenital system (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 1995	DIOXINS	• metabolic - Weight loss or decreased weight gain (rat TDLo) • liver - Changes in liver weight (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 1995	DIOXINS	• reproductive - Oogenesis (rat TDLo) • metabolic - Weight loss or decreased weight gain (rat TDLo) • endocrine system - Changes in ovarian weight (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 1995	DIOXINS	• reproductive - Endocrine system (rat TDLo) • reproductive - Growth statistics (rat TDLo) • developmental - Viability index (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 1996	DIOXINS	• reproductive - Physical (rat TDLo) • reproductive - Post-implantation mortality (rat TDLo) • developmental - Urogenital system (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 1997	DIOXINS	• endocrine system - Change in gonadotropins (rat TDLo) • endocrine system - Changes in LH (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 1997	DIOXINS	• reproductive - Urogenital system (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 1997	DIOXINS	• blood - Changes in platelet count (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 1998	DIOXINS	• reproductive - Fetal death (rat TDLo) • developmental - Other neonatal measures or effects (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 1998	DIOXINS	• reproductive - Endocrine system (rat TDLo) • reproductive - Germ cell effects (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 1998	DIOXINS	• reproductive - Spermatogenesis (rat TDLo) • reproductive - Testes, epididymis, sperm duct (rat TDLo) • biochemical - Multiple enzyme effects (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 2001	DIOXINS	• reproductive - Other postnatal measures or effects (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 2001	DIOXINS	• reproductive - Craniofacial (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 2002	DIOXINS	• cancer - Facilitates action of known carcinogen (mouse TDLo) • cancer - respiratory tumors (mouse TDLo)
RTECS®- Toxicology and Applied Pharmacology 2002	DIOXINS	• blood - Methemoglobinemia-Carboxylhemoglobin (mouse TDLo)
RTECS®- Toxicology and Applied Pharmacology 2002	DIOXINS	• metabolic - Weight loss or decreased weight gain (rat TDLo) • endocrine system - Changes in thymus weight (rat TDLo) • endocrine system - Evidence of thyroid hypofunction (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 2002	DIOXINS	• reproductive - Musculoskeletal system (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 2003	DIOXINS	• metabolic - Weight loss or decreased weight gain (rat TDLo) • broad systemic - Broad systemic toxicity (rat LDLo) • endocrine system - Changes in thymus weight (rat TDLo) • liver - Other changes (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 2003	DIOXINS	• liver - Hepatitis (hepatocellular necrosis), diffuse (mouse TDLo) • biochemical - Effect on inflammation or mediation of inflammation (mouse TDLo) • biochemical - Multiple enzyme effects (mouse TDLo)
RTECS®- Toxicology and Applied Pharmacology 2003	DIOXINS	• liver - Changes in liver weight (rat TDLo) • liver - Fatty liver degeneration (rat TDLo) • biochemical - Multiple enzyme effects (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 2003	DIOXINS	• liver - Changes in liver weight (mouse TDLo) • biochemical - Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (mouse TDLo) • biochemical - Other proteins (mouse TDLo)
RTECS®- Toxicology and Applied Pharmacology 2003	DIOXINS	• immune system - Decrease in humoral immune response (mouse TDLo) • biochemical - Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (mouse TDLo) • respiratory - Other changes (mouse TDLo)
RTECS®- Toxicology and Applied Pharmacology 2004	DIOXINS	• reproductive - Testes, epididymis, sperm duct (mouse TDLo) • metabolic - Weight loss or decreased weight gain (mouse TDLo) • endocrine system - Changes in LH (mouse TDLo)
RTECS®- Toxicology and Applied Pharmacology 2004	DIOXINS	• blood - Changes in bone marrow not included above (mouse TDLo) • immune system - Decreased immune response (mouse TDLo)
RTECS®- Toxicology and Applied Pharmacology 2004	DIOXINS	• reproductive - Fetotoxicity (mouse TDLo)
RTECS®- Toxicology and Applied Pharmacology 2004	DIOXINS	• liver - Other changes (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 2004	DIOXINS	• brain, nervous system, or behavioral effect - Food intake (animal) (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 2004	DIOXINS	• liver - Other changes (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 2004	DIOXINS	• reproductive - Spermatogenesis (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 1971	DIOXINS	• reproductive - Urogenital system (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 2005	DIOXINS	• endocrine system - Hyperglycemia (mouse TDLo) • gastrointestinal - Other changes (mouse TDLo) • biochemical - Other proteins (mouse TDLo)
RTECS®- Toxicology and Applied Pharmacology 2005	DIOXINS	• developmental - Biochemical and metabolic (rat TDLo) • reproductive - Central nervous system (rat TDLo) • reproductive - Litter size (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 2005	DIOXINS	• blood - Changes in serum composition (eg., TP, bilirubin, cholesterol) (rat TDLo) • biochemical - Lipids, including transport (rat TDLo) • liver - Other changes (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 1974	DIOXINS	• blood - Changes in serum composition (eg., TP, bilirubin, cholesterol) (mouse TDLo) • endocrine system - Changes in thymus weight (mouse TDLo) • brain, nervous system, or behavioral effect - Convulsions or effect on seizure threshold (mouse LD50) • liver - Fatty liver degeneration (mouse TDLo) • sense organ - Mydriasis (pupillary dilation) (mouse LD50) • cardiovascular - Other changes (mouse LD50) • mutagenic - Positive mutation assay: Cytogenetic Analysis (mouse orl)
RTECS®- Toxicology and Applied Pharmacology 1976	DIOXINS	• broad systemic - Broad systemic toxicity (rabbit LD50) • liver - Changes in liver weight (rat TDLo) • endocrine system - Changes in thymus weight (rat TDLo) • blood - Pigmented or nucleated red blood cells (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 1978	DIOXINS	• broad systemic - Broad systemic toxicity (rat LD50)
RTECS®- Toxicology and Applied Pharmacology 1978	DIOXINS	• liver - Changes in liver weight (rat TDLo) • liver - Hepatitis (hepatocellular necrosis), zonal (rat TDLo) • kidney or renal system - Other changes in urine composition (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 1979	DIOXINS	• developmental - Growth statistics (rat TDLo) • reproductive - Other measures of fertility (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 1980	DIOXINS	• metabolic - Weight loss or decreased weight gain (hamster LD50) • blood - Changes in serum composition (eg., TP, bilirubin, cholesterol) (hamster LD50) • gastrointestinal - Other changes (hamster LD50)
RTECS®- Toxicology and Applied Pharmacology 1981	DIOXINS	• kidney or renal system - Other changes in urine composition (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 1985	DIOXINS	• mutagenic - Positive mutation assay: DNA Inhibition ( human oth)
RTECS®- Toxicology and Applied Pharmacology 1986	DIOXINS	• metabolic - Weight loss or decreased weight gain (rat TDLo) • brain, nervous system, or behavioral effect - Food intake (animal) (rat TDLo) • endocrine system - Other changes (rat TDLo) • respiratory - Respiratory depression (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 1988	DIOXINS	• endocrine system - Estrogenic (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 1988	DIOXINS	• immune system - Decrease in humoral immune response (mouse TDLo) • immune system - Decreased immune response (mouse TDLo)
RTECS®- Toxicology and Applied Pharmacology 1988	DIOXINS	• cancer - biochemical (rat TDLo) • endocrine system - Change in gonadotropins (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 1988	DIOXINS	• endocrine system - Estrogenic (rat TDLo) • liver - Other changes (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 1989	DIOXINS	• reproductive - Craniofacial (mouse TDLo)
RTECS®- Toxicology and Applied Pharmacology 1974	DIOXINS	• mutagenic - Positive mutation assay: Cytogenetic Analysis (mouse orl)
RTECS®- Toxicology and Applied Pharmacology 1985	DIOXINS	• mutagenic - Positive mutation assay: DNA Inhibition ( human oth)
RTECS®- Toxicology Letters 2002	DIOXINS	• blood - Changes in bone marrow not included above (mouse TDLo) • endocrine system - Changes in thymus weight (mouse TDLo) • immune system - Decreased immune response (mouse TDLo)
RTECS®- Toxicology Letters 2003	DIOXINS	• mutagenic - Positive mutation assay: DNA Damage (mouse oth)
RTECS®- Toxicology Letters 2004	DIOXINS	• metabolic - Weight loss or decreased weight gain (rat LDLo) • blood - Changes in serum composition (eg., TP, bilirubin, cholesterol) (rat TDLo) • endocrine system - Evidence of thyroid hypofunction (rat TDLo) • biochemical - Other oxidoreductases (rat TDLo)
RTECS®- Toxicology Letters 2004	DIOXINS	• reproductive - Musculoskeletal system (mouse TDLo)
RTECS®- Toxicology Letters 2005	DIOXINS	• blood - Changes in spleen (mouse TDLo) • biochemical - Effect on inflammation or mediation of inflammation (mouse TDLo) • respiratory - Other changes (mouse TDLo)
RTECS®- Toxicology Letters 1992	DIOXINS	• blood - Changes in erythrocyte (RBC) count (mouse TDLo) • liver - Changes in liver weight (mouse TDLo) • endocrine system - Changes in thymus weight (mouse TDLo)
RTECS®- Toxicology Letters 1995	DIOXINS	• reproductive - Menstrual cycle changes or disorders (rat TDLo) • reproductive - Oogenesis (rat TDLo) • metabolic - Weight loss or decreased weight gain (rat TDLo)
RTECS®- Toxicology Letters 1995	DIOXINS	• reproductive - Endocrine system (rat TDLo)
RTECS®- Toxicology Letters 2003	DIOXINS	• mutagenic - Positive mutation assay: DNA Damage (mouse oth)
RTECS®- Toxicology Letters 2007	DIOXINS	• mutagenic - Positive mutation assay: DNA Damage ( human mmr)
RTECS®- Toxicology 1996	DIOXINS	• metabolic - Weight loss or decreased weight gain (rat TDLo) • endocrine system - Changes in spleen weight (rat TDLo) • endocrine system - Changes in thymus weight (rat TDLo) • immune system - Decreased immune response (rat TDLo) • immune system - Increase in humoral immune response (rat TDLo)
RTECS®- Toxicology 2000	DIOXINS	• cardiovascular - BP elevation not characterized in autonomic section (rat TDLo) • metabolic - Body temperature decrease (rat TDLo) • cardiovascular - Pulse rate (rat TDLo)
RTECS®- Toxicology 2002	DIOXINS	• biochemical - Catalases (rat TDLo) • liver - Other changes (rat TDLo) • biochemical - Other oxidoreductases (rat TDLo)
RTECS®- Toxicology 2002	DIOXINS	• endocrine system - Changes in testicular weight (rat TDLo) • biochemical - Lipids, including transport (rat TDLo) • biochemical - Multiple enzyme effects (rat TDLo)
RTECS®- Toxicology 2002	DIOXINS	• endocrine system - Evidence of thyroid hypofunction (rat TDLo) • biochemical - Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (rat TDLo) • liver - Other changes (rat TDLo)
RTECS®- Toxicology 2002	DIOXINS	• metabolic - Weight loss or decreased weight gain (mouse TDLo) • liver - Changes in liver weight (mouse TDLo) • endocrine system - Changes in thymus weight (mouse TDLo)
RTECS®- Toxicology 2002	DIOXINS	• endocrine system - Changes in thymus weight (mouse TDLo) • immune system - Decrease in humoral immune response (mouse TDLo) • biochemical - Effect on inflammation or mediation of inflammation (mouse TDLo)
RTECS®- Toxicology 2002	DIOXINS	• biochemical - Lipids, including transport (mouse TDLo) • liver - Other changes (mouse TDLo) • brain, nervous system, or behavioral effect - Other degenerative changes (mouse TDLo)
RTECS®- Toxicology 2002	DIOXINS	• blood - Changes in spleen (mouse TDLo) • biochemical - Multiple enzyme effects (mouse TDLo)
RTECS®- Toxicology 2002	DIOXINS	• liver - Other changes (rat TDLo) • biochemical - Other proteins (rat TDLo)
RTECS®- Toxicology 2003	DIOXINS	• immune system - Decrease in cellular immune response (mouse TDLo) • immune system - Decrease in humoral immune response (mouse TDLo) • biochemical - Effect on inflammation or mediation of inflammation (mouse TDLo)
RTECS®- Toxicology 2004	DIOXINS	• liver - Changes in liver weight (mouse TDLo) • endocrine system - Changes in thymus weight (mouse TDLo) • immune system - Decrease in humoral immune response (mouse TDLo)
RTECS®- Toxicology 2004	DIOXINS	• reproductive - Immune and reticuloendothelial system (rat TDLo)
RTECS®- Toxicology 1981	DIOXINS	• reproductive - Fetotoxicity (mouse TDLo)
RTECS®- Toxicology 1981	DIOXINS	• reproductive - Uterus, cervix, vagina (rat TDLo)
RTECS®- Toxicology 1983	DIOXINS	• mutagenic - Positive mutation assay: Unscheduled DNA Synthesis (rat orl)
RTECS®- Toxicology 1983	DIOXINS	• reproductive - Prostate, seminal vesicle, Cowper's gland, accessory glands (rat TDLo) • biochemical - Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (rat TDLo)
RTECS®- Toxicology 1985	DIOXINS	• endocrine system - Evidence of thyroid hypofunction (rat TDLo) • biochemical - Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (rat TDLo)
RTECS®- Toxicology 1987	DIOXINS	• metabolic - Weight loss or decreased weight gain (rat TDLo) • endocrine system - Evidence of thyroid hypofunction (rat TDLo) • brain, nervous system, or behavioral effect - Food intake (animal) (rat TDLo) • endocrine system - Hypoglycemia (rat TDLo) • endocrine system - Other changes (rat LDLo)
RTECS®- Toxicology 1988	DIOXINS	• endocrine system - Adrenal cortex hyperplasia (rat TDLo) • broad systemic - Broad systemic toxicity (rat LDLo) • endocrine system - Changes in thymus weight (rat TDLo) • brain, nervous system, or behavioral effect - Food intake (animal) (rat TDLo)
RTECS®- Toxicology 1989	DIOXINS	• mutagenic - Positive mutation assay: other mutation test systems (mouse orl)
RTECS®- Toxicology 1990	DIOXINS	• immune system - Decrease in cellular immune response (mouse TDLo) • biochemical - Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (mouse TDLo)
RTECS®- Toxicology 1992	DIOXINS	• reproductive - Prostate, seminal vesicle, Cowper's gland, accessory glands (rat TDLo) • reproductive - Testes, epididymis, sperm duct (rat TDLo) • metabolic - Weight loss or decreased weight gain (rat TDLo) • endocrine system - Androgenic (rat TDLo) • endocrine system - Changes in testicular weight (rat TDLo)
RTECS®- Toxicology 1993	DIOXINS	• blood - Changes in spleen (mouse TDLo) • immune system - Decrease in cellular immune response (mouse TDLo) • immune system - Decreased immune response (mouse TDLo) • liver - Other changes (mouse TDLo) • biochemical - Other hydrolases (mouse TDLo)
RTECS®- Toxicology 1994	DIOXINS	• reproductive - Prostate, seminal vesicle, Cowper's gland, accessory glands (rat TDLo) • reproductive - Testes, epididymis, sperm duct (rat TDLo) • metabolic - Weight loss or decreased weight gain (rat TDLo)
RTECS®- Toxicology 1994	DIOXINS	• immune system - Decrease in humoral immune response (mouse TDLo)
RTECS®- Toxicology 1983	DIOXINS	• mutagenic - Positive mutation assay: Unscheduled DNA Synthesis (rat orl)
RTECS®- Toxicology 1989	DIOXINS	• mutagenic - Positive mutation assay: other mutation test systems (mouse orl)
RTECS®- Veterinary and Human Toxicology 2001	DIOXINS	• reproductive - Growth statistics (mammal TDLo) • reproductive - Mating performance (mammal TDLo) • reproductive - Post-implantation mortality (mammal TDLo) • reproductive - Viability index (mammal TDLo) • metabolic - Weight loss or decreased weight gain (mammal TDLo) • metabolic - Fe (mammal TDLo) • blood - Other changes (mammal TDLo) • brain, nervous system, or behavioral effect - Other degenerative changes (mammal TDLo) • brain, nervous system, or behavioral effect - Somnolence (general depressed activity) (mammal TDLo)
RTECS®- Veterinary and Human Toxicology 2001	DIOXINS	• musculoskeletal - Changes in teeth and supporting structures (mammal TDLo) • metabolic - Weight loss or decreased weight gain (mammal TDLo)

references

government/industry list/academic study	reference
Association of Occupational and Environmental Clinics	AOEC (Association of Occupational and Environmental Clinics). 2009. AEOC exposures codes and asthmagen designation.
Canada - Prohibited and Restricted Cosmetics Ingredients	Health Canada. 2007. List of Prohibited and Restricted Cosmetic Ingredients. Canada's Cosmetic Ingredient Hotlist. March 2007.
EPA Clean Water Act - Priority Pollutants
European Commission on Endocrine Disruption	EU (European Union)- Strategy for Endocrine Disrupters 2007. Commision on endocrin disruption requested by the European Parliament in 1998.
EPA Hazardous Air Pollutants	EPA (U.S. Environmental Protection Agency). 2005. Office of Air. The 112(b)1 Hazardous Air Pollutants List (as modified). Last modified: 12 Dec 2005.
National Library of Medicine HazMap	NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
Int'l Agency for Research on Cancer (IARC) - Carcinogens	IARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures).
NTP Report on Carcinogens, 11th Edition	NTP (National Toxicology Program). 2005. Report on Carcinogens, Eleventh Edition; U.S. Department of Health and Human Services, Public Health Service, National Toxicology Program.
Our Stolen Future Endocrine Disruptors	Colborn T, D Dumanoski, JP Myers. 2006. Widespread Pollutants with Endocrine-disrupting Effects. Updated from original listing in "Our Stolen Future" (1996).
Aarhus Protocol on Persistent Organic Pollutants	Aarhus LRTAP. 1998. Aarhus Protocol on Persistent Organic Pollutants (POPs). Geneva Convention on Long-range Transboundary Air Pollution, United Nations Environment Program.
Canada PBTs - Accelerated Reduction/Elimination of Toxics (ARET)	EC (Environment Canada). 1994. Accelerated Reduction/Elimination of Toxics (ARET). ARET substance list of persistent, bioaccumulative and toxic chemicals.
Great Lakes BTS (Binational Toxics Strategy) PBTs	Great Lakes BTS (Binational Toxics Strategy). 1997. Canada-United States Strategy for the Virtual Elimination of Persistent Toxic Substances in the Great Lakes. Appendix I - Level 1 and Level 2 substances.
OSPAR PBTs - Substances of Possible Concern	OSPAR (Oslo-Paris). 2002. OSPAR List of Substances of Possible Concern. Secondary OSPAR List of Substances of Possible Concern. Secondary OSPAR. Place Published, OSPAR Convention for the Protection of the Marine Environement of North-East Atlanic.
EPA PBTs - Waste Minimization Program (RCRA)	EPA (U.S. Environmental Protection Agency). 1998. Resource Conservatin and Recovery Act (RCRA) Waste Minimization Program - priority chemicals for elimination or reduction.
United Nations Environment Programme/POPs Treaty	UNEP (United Nations Environment Programme). 2001. Stockholm Convention on Persistent Organic Pollutants (POPs) — POPs Treaty.
EPA Toxic Release Inventory PBTs	EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
California EPA Proposition 65	California EPA (California Environmental Protection Agency). 9/2008. Office of Environmental Health Hazard Assessment. Safe Drinking Water and Toxic Enforcement Act of 1986. Chemicals known to the State to cause cancer or reproductive toxicity.
Scorecard.org Toxicity Information	Agency for Toxic Substances and Disease Registry. Minimal risk Levels for Hazardous Substances. January 2004. http://www.atsdr.cdc.gov/mrls.html, US EPA, Air Risk Information Support Center. Health Effects Notebook for Hazardous Air Pollutants. http://www.epa.gov/ttnatw01/hlthef/hapindex.html, LaDou, J. (ed.). Occupational Medicine. Appleton & Lange, Norwalk, CN. 1990., California EPA, Office of Environmental Health Hazard Assessment. Air Toxics Hot Spots Program Risk Assessment Guidelines, Part III: Technical Support Document 'Determination of Noncancer Chronic Reference Exposure Levels'. Includes all Chronic Reference Exposure Levels (CRELs) adopted by OEHHA as of August 2003 (http://www.oehha.ca.gov/air/chronic_rels/AllChrels.html, plus draft CRELS proposed through March 2004 (http://www.oehha.ca.gov/air/chronic_rels/index.html., National Institute for Occupational Safety and Health's Registry of Toxic Effects of Chemical Substances. See Environmental Defense's Suspect Hazard Identification documentation.
Scorecard.org Toxicity Information	Agency for Toxic Substances and Disease Registry. Minimal risk Levels for Hazardous Substances. January 2004. http://www.atsdr.cdc.gov/mrls.html, Nordic Council of Ministers (Nordic Allergy Project). Kriteriedokumenter fra nordisk allergiprojekt - vurdering af 50 kemiske stoffers evne til at forarsage allergi, en litteraturgennemgang. Nord 1991:51. Copenhagen, 1991.
Scorecard.org Toxicity Information	BKH/European Commission. Towards the establishment of a priority list of substances for further evaluation of their role in endocrine disruption: - preparation of a candidate list of substances as a basis for priority setting. Final report-November 2000. http://europa.eu.int/comm/environment/docum/01262_en.htm#bkh. Category 1 chemicals from Annex 1: Candidate list of 553 substances. http://europa.eu.int/comm/environment/docum/bkh_annex_01.pdf, Brucker-Davis, F. Effects of Environmental Synthetic Chemicals on Thyroid Function. Thyroid. 8(9): 827-856. 1998., Illinois EPA. Endocrine Disruptors Strategy. 1997. (Table 1: Preliminary List of Chemicals Associated with Endocrine System Effects in Animals and Humans or In Vitro). http://www.nihs.go.jp/hse/environ/illiepatable.htm, Japanese National Institute of Health Sciences. Lists of Paradigmatic Chemicals. http://www.nihs.go.jp/hse/endocrine-e/paradigm/paradigm.html, Keith, L.H. (ed.). Environmental Endocrine Disruptors. John Wiley & Sons, NY. 1997. http://www.wileyeurope.com/cda/product/0,,0471191450%7Cdesc%7C3037,00.html, California EPA, Office of Environmental Health Hazard Assessment. Air Toxics Hot Spots Program Risk Assessment Guidelines, Part III: Technical Support Document 'Determination of Noncancer Chronic Reference Exposure Levels'. Includes all Chronic Reference Exposure Levels (CRELs) adopted by OEHHA as of August 2003 (http://www.oehha.ca.gov/air/chronic_rels/AllChrels.html, plus draft CRELS proposed through March 2004 (http://www.oehha.ca.gov/air/chronic_rels/index.html., National Institute for Occupational Safety and Health's Registry of Toxic Effects of Chemical Substances. See Environmental Defense's Suspect Hazard Identification documentation., World Wildlife Fund. Our Stolen Future. Widespread Pollutants with Endocrine-disrupting Effects. http://www.ourstolenfuture.org/Basics/chemlist.htm. The WWF list is derived from references detailed at http://www.ourstolenfuture.org/Sources/chemsources.htm and was originally published in: Colborn, T., F.S. vom Saal, and A.M. Soto. Developmental Effects of Endocrine-Disrupting Chemicals In Wildlife and Humans. Environmental Health Perspectives 101(5): 378-384. 1993.
Scorecard.org Toxicity Information	US EPA, Air Risk Information Support Center. Health Effects Notebook for Hazardous Air Pollutants. http://www.epa.gov/ttnatw01/hlthef/hapindex.html, A Relational Database of Hazardous Chemicals and Occupational Diseases. Browse Haz-Map by Adverse Effects http://hazmap.nlm.nih.gov/hazmapadv.html, Klaassen, C., M. Amdur and J. Doull (eds.). Casarett and Doull's Toxicology. The Basic Science of Poisons, 5th Ed. Pergamon Press, NY. 1996., National Institute for Occupational Safety and Health's Registry of Toxic Effects of Chemical Substances. See Environmental Defense's Suspect Hazard Identification documentation.
Scorecard.org Toxicity Information	US EPA, Air Risk Information Support Center. Health Effects Notebook for Hazardous Air Pollutants. http://www.epa.gov/ttnatw01/hlthef/hapindex.html, LaDou, J. (ed.). Occupational Medicine. Appleton & Lange, Norwalk, CN. 1990., California EPA, Office of Environmental Health Hazard Assessment. Air Toxics Hot Spots Program Risk Assessment Guidelines, Part III: Technical Support Document 'Determination of Noncancer Chronic Reference Exposure Levels'. Includes all Chronic Reference Exposure Levels (CRELs) adopted by OEHHA as of August 2003 (http://www.oehha.ca.gov/air/chronic_rels/AllChrels.html, plus draft CRELS proposed through March 2004 (http://www.oehha.ca.gov/air/chronic_rels/index.html., National Institute for Occupational Safety and Health's Registry of Toxic Effects of Chemical Substances. See Environmental Defense's Suspect Hazard Identification documentation., Zimmerman, H.J. and J.H. Lewis. Chemical- and Toxin-Induced Hepatotoxicity. Gastroenterology Clinics of North America. 24(4): 1027-1045. 1995. (Table 3: Forms of environmental hepatic injury).
Scorecard.org Toxicity Information	Merck & Co. The Merck Manual of Diagnosis and Therapy. TABLE 226-1. Common Nephrotoxic Agents http://www.merck.com/pubs/mmanual/tables/226tb1.htm, National Institute for Occupational Safety and Health's Registry of Toxic Effects of Chemical Substances. See Environmental Defense's Suspect Hazard Identification documentation.
Scorecard.org Toxicity Information	California EPA, Office of Environmental Health Hazard Assessment. Air Toxics Hot Spots Program Risk Assessment Guidelines, Part III: Technical Support Document 'Determination of Noncancer Chronic Reference Exposure Levels'. Includes all Chronic Reference Exposure Levels (CRELs) adopted by OEHHA as of August 2003 (http://www.oehha.ca.gov/air/chronic_rels/AllChrels.html, plus draft CRELS proposed through March 2004 (http://www.oehha.ca.gov/air/chronic_rels/index.html.
Scorecard.org Toxicity Information	California EPA, Office of Environmental Health Hazard Assessment. Air Toxics Hot Spots Program Risk Assessment Guidelines, Part III: Technical Support Document 'Determination of Noncancer Chronic Reference Exposure Levels'. Includes all Chronic Reference Exposure Levels (CRELs) adopted by OEHHA as of August 2003 (http://www.oehha.ca.gov/air/chronic_rels/AllChrels.html, plus draft CRELS proposed through March 2004 (http://www.oehha.ca.gov/air/chronic_rels/index.html., National Institute for Occupational Safety and Health's Registry of Toxic Effects of Chemical Substances. See Environmental Defense's Suspect Hazard Identification documentation.
Scorecard.org Toxicity Information	Proposition 65 List of Carcinogens (July 2004) can be obtained from http://www.oehha.ca.gov/prop65/prop65_list/Newlist.html.
Scorecard.org Toxicity Information	Proposition 65 List of Carcinogens (July 2004) can be obtained from http://www.oehha.ca.gov/prop65/prop65_list/Newlist.html.
RTECS®- Ambio 1972	RTECS®- Ambio. A Journal of the Human Environment. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1972- 1,1,1972
RTECS®- Ambio 1972	RTECS®- Ambio. A Journal of the Human Environment. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1972- 1,32,1972
RTECS®- Ambio 1972	RTECS®- Ambio. A Journal of the Human Environment. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1,1,1972
RTECS®- Ambio 1972	RTECS®- Ambio. A Journal of the Human Environment. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1,32,1972
RTECS®- Annals of the New York Academy of Sciences 1979	RTECS®- Annals of the New York Academy of Sciences. (New York Academy of Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877- -,419,1979
RTECS®- Annals of the New York Academy of Sciences 1979	RTECS®- Annals of the New York Academy of Sciences. (New York Academy of Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877- 320,204,1979
RTECS®- Annals of the New York Academy of Sciences 1979	RTECS®- Annals of the New York Academy of Sciences. (New York Academy of Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877- 320,397,1979
RTECS®- Archiv fuer Toxikologie 1983	RTECS®- Archiv fuer Toxikologie. (Berlin, Fed. Rep. Ger.) V.15-31, 1954-74. For publisher information, see ARTODN. 53,177,1983
RTECS®- Archives of Environmental Contamination and Toxicology 1988	RTECS®- Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- 17,33,1988
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RTECS®- Archives of Toxicology 1988	RTECS®- Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- 62,146,1988
RTECS®- Archives of Toxicology 1993	RTECS®- Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- 67,591,1993
RTECS®- Archives of Toxicology 1994	RTECS®- Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- 69,87,1994
RTECS®- Archives of Toxicology 2002	RTECS®- Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- 76,113,2002
RTECS®- Archives of Toxicology 2002	RTECS®- Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- 76,360,2002
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RTECS®- Biochemical Pharmacology 1983	RTECS®- Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- 32,991,1983
RTECS®- Biochemical Pharmacology 1984	RTECS®- Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- 33,2531,1984
RTECS®- Biochemical Pharmacology 1986	RTECS®- Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- 35,2737,1986
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RTECS®- Biochemical Pharmacology 1988	RTECS®- Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- 36,1535,1988
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RTECS®- Biochemical Pharmacology 1990	RTECS®- Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- 39,485,1990
RTECS®- Biochemical Pharmacology 2000	RTECS®- Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- 59,1147,2000
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RTECS®- Canadian Journal of Physiology and Pharmacology 1985	RTECS®- Canadian Journal of Physiology and Pharmacology. (National Research Council of Canada, Publication Sales and Distribution, Ottawa ON K1A OR6, Canada) V.42- 1964- 63,1537,1985
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RTECS®- Mutation Research 1977	RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- -1964 46,305,1977
RTECS®- Mutation Research 1978	RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- -1964 47,141,1978
RTECS®- National Cancer Institute Carcinogenesis Technical Report Series 1982	RTECS®- National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD) No.0-205. For publisher information, see NTPTR*. NCI-TR-201,1982
RTECS®- National Cancer Institute Carcinogenesis Technical Report Series	RTECS®- National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD) No.0-205. For publisher information, see NTPTR*. NCI-TR-201-82
RTECS®- National Technical Information Service 4117	RTECS®- National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. OTS0544117
RTECS®- National Technical Information Service 3445	RTECS®- National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. PB82-163445
RTECS®- National Technical Information Service 3684	RTECS®- National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. PB82-163684
RTECS®- National Toxicology Program Technical Report Series 1982	RTECS®- National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- NTP-TR-209,1982
RTECS®- Nature 1979	RTECS®- Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736) V.1- 1869- 278,548,1979
RTECS®- Neurotoxicology and Teratology 1989	RTECS®- Neurotoxicology and Teratology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.9- 1987- 11,13,1989
RTECS®- Neurotoxicology and Teratology 1992	RTECS®- Neurotoxicology and Teratology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.9- 1987- 14,433,1992
RTECS®- Neurotoxicology and Teratology 1993	RTECS®- Neurotoxicology and Teratology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.9- 1987- 15,365,1993
RTECS®- Neurotoxicology and Teratology 2001	RTECS®- Neurotoxicology and Teratology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.9- 1987- 22,511,2001
RTECS®- Neurotoxicology and Teratology 2002	RTECS®- Neurotoxicology and Teratology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.9- 1987- 24,209,2002
RTECS®- Neurotoxicology and Teratology 2003	RTECS®- Neurotoxicology and Teratology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.9- 1987- 25,459,2003
RTECS®- Neurotoxicology 2002	RTECS®- Neurotoxicology. (Intox Press, Inc., POB 34075, Little Rock, AR 72203) V.1- 1979- 23,783,2002
RTECS®- Neurotoxicology 2003	RTECS®- Neurotoxicology. (Intox Press, Inc., POB 34075, Little Rock, AR 72203) V.1- 1979- 24,207,2003
RTECS®- Pergamon Series on Environmental Science 1982	RTECS®- Pergamon Series on Environmental Science. (Oxford, UK) V.1-7, 1978-82. Discontinued. 5,419,1982
RTECS®- Pergamon Series on Environmental Science 1982	RTECS®- Pergamon Series on Environmental Science. (Oxford, UK) V.1-7, 1978-82. Discontinued. 5,429,1982
RTECS®- Pesticide & Toxic Chemical News 1977	RTECS®- Pesticide & Toxic Chemical News. (Food Chemical News, Inc., 400 Wyatt Bldg., 777 14th St., NW, Washington, DC 20005) V.1- 1972- 5,12,1977
RTECS®- Reproductive Toxicology 2001	RTECS®- Reproductive Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1987- 15,377,2001
RTECS®- Reproductive Toxicology 2005	RTECS®- Reproductive Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1987- 20,21,2005
RTECS®- Reproductive Toxicology 2006	RTECS®- Reproductive Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1987- 21,301,2006
RTECS®- Research Communications in Chemical Pathology and Pharmacology 1978	RTECS®- Research Communications in Chemical Pathology and Pharmacology. (PJD Pub. Ltd., P.O. Box 966, Westbury, NY 11590) V.1- 1970- 20,101,1978
RTECS®- Scientific American 1986	RTECS®- Scientific American. (Scientific American, Inc., 415 Madison Ave., New York, NY 10017) V.1- -1859 254,29,1986
RTECS®- Teratogenesis, Carcinogenesis, and Mutagenesis 2000	RTECS®- Teratogenesis, Carcinogenesis, and Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1980- 20,73,2000
RTECS®- Teratogenesis, Carcinogenesis, and Mutagenesis 1984	RTECS®- Teratogenesis, Carcinogenesis, and Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1980- 4,427,1984
RTECS®- Teratology, The International Journal of Abnormal Development 1980	RTECS®- Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- 21,62A,1980
RTECS®- Teratology, The International Journal of Abnormal Development 1982	RTECS®- Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- 25(1),21A,1982
RTECS®- Teratology, The International Journal of Abnormal Development 1986	RTECS®- Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- 33,29,1986
RTECS®- Teratology, The International Journal of Abnormal Development 1989	RTECS®- Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- 40,292,1989
RTECS®- Teratology, The International Journal of Abnormal Development 1991	RTECS®- Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- 44,385,1991
RTECS®- Teratology, The International Journal of Abnormal Development 1997	RTECS®- Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- 55,326,1997
RTECS®- Toksikologicheskii Vestnik 1998	RTECS®- Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown (5),2,1998
RTECS®- Toksikologicheskii Vestnik 1994	RTECS®- Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown (1),7,1994
RTECS®- Toksikologicheskii Vestnik 1998	RTECS®- Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown (2),20,1998
RTECS®- Toksikologicheskii Vestnik 1998	RTECS®- Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown (5),2,1998
RTECS®- Toksikologicheskii Vestnik 2003	RTECS®- Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown (6),34,2003
RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 1999	RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V. 41, Jan. 1998- 51,259,1999
RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 1999	RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V. 41, Jan. 1998- 52,45,1999
RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2000	RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V. 41, Jan. 1998- 56,114,2000
RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2000	RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V. 41, Jan. 1998- 56,374,2000
RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2002	RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V. 41, Jan. 1998- 66,117,2002
RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2002	RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V. 41, Jan. 1998- 66,62,2002
RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2002	RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V. 41, Jan. 1998- 68,465,2002
RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2002	RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V. 41, Jan. 1998- 68,479,2002
RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2002	RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V. 41, Jan. 1998- 69,109,2002
RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2002	RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V. 41, Jan. 1998- 69,117,2002
RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2002	RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V. 41, Jan. 1998- 69,482,2002
RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2003	RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V. 41, Jan. 1998- 71,112,2003
RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2003	RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V. 41, Jan. 1998- 71,84,2003
RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V 2003	RTECS®- Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 ) V. 41, Jan. 1998- 76,171,2003
RTECS®- Toxicologist 2001	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 1,114,2001
RTECS®- Toxicologist 2001	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 1,68,2001
RTECS®- Toxicologist 1990	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 10,313,1990
RTECS®- Toxicologist 1993	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 13,103,1993
RTECS®- Toxicologist 1993	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 13,104,1993
RTECS®- Toxicologist 1994	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 14,197,1994
RTECS®- Toxicologist 1994	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 14,382,1994
RTECS®- Toxicologist 1995	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 15,292,1995
RTECS®- Toxicologist 1983	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 3,68,1983
RTECS®- Toxicologist 2005	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 44,112,2005
RTECS®- Toxicologist 2005	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 44,113,2005
RTECS®- Toxicologist 2005	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 44,138,2005
RTECS®- Toxicologist 2005	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 44,139,2005
RTECS®- Toxicologist 2005	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 44,145,2005
RTECS®- Toxicologist 2005	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 44,172,2005
RTECS®- Toxicologist 2005	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 44,173,2005
RTECS®- Toxicologist 2005	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 44,181,2005
RTECS®- Toxicologist 2005	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 44,222,2005
RTECS®- Toxicologist 2005	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 44,251,2005
RTECS®- Toxicologist 2005	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 44,279,2005
RTECS®- Toxicologist 2005	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 44,372,2005
RTECS®- Toxicologist 2005	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 44,389,2005
RTECS®- Toxicologist 2005	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 44,416,2005
RTECS®- Toxicologist 2005	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 44,418,2005
RTECS®- Toxicologist 2005	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 44,439,2005
RTECS®- Toxicologist 2001	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 60,138,2001
RTECS®- Toxicologist 2001	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 60,181,2001
RTECS®- Toxicologist 2001	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 60,201,2001
RTECS®- Toxicologist 2001	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 60,235,2001
RTECS®- Toxicologist 2001	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 60,236,2001
RTECS®- Toxicologist 2001	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 60,24,2001
RTECS®- Toxicologist 2001	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 60,249,2001
RTECS®- Toxicologist 2001	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 60,25,2001
RTECS®- Toxicologist 2001	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 60,252,2001
RTECS®- Toxicologist 2001	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 60,269,2001
RTECS®- Toxicologist 2001	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 60,273,2001
RTECS®- Toxicologist 2001	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 60,274,2001
RTECS®- Toxicologist 2001	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 60,331,2001
RTECS®- Toxicologist 2001	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 60,332,2001
RTECS®- Toxicologist 2001	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 60,333,2001
RTECS®- Toxicologist 2001	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 60,440,2001
RTECS®- Toxicologist 2001	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 60,441,2001
RTECS®- Toxicologist 2001	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 60,442,2001
RTECS®- Toxicologist 2001	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 60,444,2001
RTECS®- Toxicologist 2002	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 66,132,2002
RTECS®- Toxicologist 2002	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 66,157,2002
RTECS®- Toxicologist 2002	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 66,168,2002
RTECS®- Toxicologist 2002	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 66,169,2002
RTECS®- Toxicologist 2002	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 66,170,2002
RTECS®- Toxicologist 2002	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 66,178,2002
RTECS®- Toxicologist 2002	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 66,21,2002
RTECS®- Toxicologist 2002	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 66,300,2002
RTECS®- Toxicologist 2002	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 66,333,2002
RTECS®- Toxicologist 2002	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 66,334,2002
RTECS®- Toxicologist 2002	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 66,376,2002
RTECS®- Toxicologist 2002	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 66,62,2002
RTECS®- Toxicologist 2002	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 66,9,2002
RTECS®- Toxicologist	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 72(Suppl
RTECS®- Toxicologist 2003	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 72(Suppl 1),231,2003
RTECS®- Toxicologist 2003	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 72(Suppl 1),365,2003
RTECS®- Toxicologist 2003	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 72(Suppl 1),366,2003
RTECS®- Toxicologist 2003	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 72,109,2003
RTECS®- Toxicologist 2003	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 72,113,2003
RTECS®- Toxicologist 2003	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 72,121,2003
RTECS®- Toxicologist 2003	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 72,125,2003
RTECS®- Toxicologist 2003	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 72,230,2003
RTECS®- Toxicologist 2003	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 72,264,2003
RTECS®- Toxicologist 2003	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 72,30,2003
RTECS®- Toxicologist 2003	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 72,361,2003
RTECS®- Toxicologist 2003	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 72,362,2003
RTECS®- Toxicologist 2003	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 72,369,2003
RTECS®- Toxicologist 2003	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 72,66,2003
RTECS®- Toxicologist 2003	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 72,77,2003
RTECS®- Toxicologist 2004	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 78,18,2004
RTECS®- Toxicologist 2004	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 78,189,2004
RTECS®- Toxicologist 2004	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 78,19,2004
RTECS®- Toxicologist 2004	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 78,218,2004
RTECS®- Toxicologist 2004	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 78,245,2004
RTECS®- Toxicologist 2004	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 78,246,2004
RTECS®- Toxicologist 2004	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 78,247,2004
RTECS®- Toxicologist 2004	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 78,248,2004
RTECS®- Toxicologist 2004	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 78,367,2004
RTECS®- Toxicologist 2004	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 78,381,2004
RTECS®- Toxicologist 2004	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 78,98,2004
RTECS®- Toxicologist 2003	RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- 72,369,2003
RTECS®- Toxicology and Applied Pharmacology 1990	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 102,362,1990
RTECS®- Toxicology and Applied Pharmacology 1990	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 105,78,1990
RTECS®- Toxicology and Applied Pharmacology 1990	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 106,112,1990
RTECS®- Toxicology and Applied Pharmacology 1992	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 112,128,1992
RTECS®- Toxicology and Applied Pharmacology 1994	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 124,82,1994
RTECS®- Toxicology and Applied Pharmacology 1994	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 127,241,1994
RTECS®- Toxicology and Applied Pharmacology 1994	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 127,250,1994
RTECS®- Toxicology and Applied Pharmacology 1994	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 128,97,1994
RTECS®- Toxicology and Applied Pharmacology 1995	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 131,108,1995
RTECS®- Toxicology and Applied Pharmacology 1995	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 133,285,1995
RTECS®- Toxicology and Applied Pharmacology 1995	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 133,313,1995
RTECS®- Toxicology and Applied Pharmacology 1995	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 133,321,1995
RTECS®- Toxicology and Applied Pharmacology 1995	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 134,241,1995
RTECS®- Toxicology and Applied Pharmacology 1996	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 140,146,1996
RTECS®- Toxicology and Applied Pharmacology 1997	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 142,264,1997
RTECS®- Toxicology and Applied Pharmacology 1997	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 146,11,1997
RTECS®- Toxicology and Applied Pharmacology 1997	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 146,217,1997
RTECS®- Toxicology and Applied Pharmacology 1998	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 150,254,1998
RTECS®- Toxicology and Applied Pharmacology 1998	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 150,383,1998
RTECS®- Toxicology and Applied Pharmacology 1998	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 150,427,1998
RTECS®- Toxicology and Applied Pharmacology 2001	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 173,38,2001
RTECS®- Toxicology and Applied Pharmacology 2001	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 174,216,2001
RTECS®- Toxicology and Applied Pharmacology 2002	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 179,21,2002
RTECS®- Toxicology and Applied Pharmacology 2002	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 181,32,2002
RTECS®- Toxicology and Applied Pharmacology 2002	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 181,38,2002
RTECS®- Toxicology and Applied Pharmacology 2002	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 184,57,2002
RTECS®- Toxicology and Applied Pharmacology 2003	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 187,128,2003
RTECS®- Toxicology and Applied Pharmacology 2003	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 190,120,2003
RTECS®- Toxicology and Applied Pharmacology 2003	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 191,12,2003
RTECS®- Toxicology and Applied Pharmacology 2003	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 192,262,2003
RTECS®- Toxicology and Applied Pharmacology 2003	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 192,275,2003
RTECS®- Toxicology and Applied Pharmacology 2004	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 194,239,2004
RTECS®- Toxicology and Applied Pharmacology 2004	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 197,185,2004
RTECS®- Toxicology and Applied Pharmacology 2004	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 197,211,2004
RTECS®- Toxicology and Applied Pharmacology 2004	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 197,212,2004
RTECS®- Toxicology and Applied Pharmacology 2004	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 197,214,2004
RTECS®- Toxicology and Applied Pharmacology 2004	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 197,215,2004
RTECS®- Toxicology and Applied Pharmacology 2004	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 197,354,2004
RTECS®- Toxicology and Applied Pharmacology 1971	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 20,396,1971
RTECS®- Toxicology and Applied Pharmacology 2005	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 205,89,2005
RTECS®- Toxicology and Applied Pharmacology 2005	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 205,98,2005
RTECS®- Toxicology and Applied Pharmacology 2005	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 207,1,2005
RTECS®- Toxicology and Applied Pharmacology 1974	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 29,229,1974
RTECS®- Toxicology and Applied Pharmacology 1976	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 35,553,1976
RTECS®- Toxicology and Applied Pharmacology 1978	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 45,513,1978
RTECS®- Toxicology and Applied Pharmacology 1978	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 46(2),279,1978
RTECS®- Toxicology and Applied Pharmacology 1979	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 50,241,1979
RTECS®- Toxicology and Applied Pharmacology 1980	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 55,67,1980
RTECS®- Toxicology and Applied Pharmacology 1981	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 57,156,1981
RTECS®- Toxicology and Applied Pharmacology 1985	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 77,434,1985
RTECS®- Toxicology and Applied Pharmacology 1986	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 84,45,1986
RTECS®- Toxicology and Applied Pharmacology 1988	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 92,368,1988
RTECS®- Toxicology and Applied Pharmacology 1988	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 94,141,1988
RTECS®- Toxicology and Applied Pharmacology 1988	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 94,496,1988
RTECS®- Toxicology and Applied Pharmacology 1988	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 95,435,1988
RTECS®- Toxicology and Applied Pharmacology 1989	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 98,487,1989
RTECS®- Toxicology and Applied Pharmacology 1974	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 29,229,1974
RTECS®- Toxicology and Applied Pharmacology 1985	RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 77,434,1985
RTECS®- Toxicology Letters 2002	RTECS®- Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- 129,1,2002
RTECS®- Toxicology Letters 2003	RTECS®- Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- 145,55,2003
RTECS®- Toxicology Letters 2004	RTECS®- Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- 147,133,2004
RTECS®- Toxicology Letters 2004	RTECS®- Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- 150,285,2004
RTECS®- Toxicology Letters 2005	RTECS®- Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- 157,89,2005
RTECS®- Toxicology Letters 1992	RTECS®- Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- 60,247,1992
RTECS®- Toxicology Letters 1995	RTECS®- Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- 78,219,1995
RTECS®- Toxicology Letters 1995	RTECS®- Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- 78,253,1995
RTECS®- Toxicology Letters 2003	RTECS®- Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 145,55,2003
RTECS®- Toxicology Letters 2007	RTECS®- Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 172,146,2007
RTECS®- Toxicology 1996	RTECS®- Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- 106,221,1996
RTECS®- Toxicology 2000	RTECS®- Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- 145,227,2000
RTECS®- Toxicology 2002	RTECS®- Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- 171,117,2002
RTECS®- Toxicology 2002	RTECS®- Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- 171,127,2002
RTECS®- Toxicology 2002	RTECS®- Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- 171,73,2002
RTECS®- Toxicology 2002	RTECS®- Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- 172,125,2002
RTECS®- Toxicology 2002	RTECS®- Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- 172,49,2002
RTECS®- Toxicology 2002	RTECS®- Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- 175,73,2002
RTECS®- Toxicology 2002	RTECS®- Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- 178,241,2002
RTECS®- Toxicology 2002	RTECS®- Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- 178,45,2002
RTECS®- Toxicology 2003	RTECS®- Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- 188,15,2003
RTECS®- Toxicology 2004	RTECS®- Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- 197,15,2004
RTECS®- Toxicology 2004	RTECS®- Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- 197,57,2004
RTECS®- Toxicology 1981	RTECS®- Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- 20,299,1981
RTECS®- Toxicology 1981	RTECS®- Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- 21,77,1981
RTECS®- Toxicology 1983	RTECS®- Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- 28,133,1983
RTECS®- Toxicology 1983	RTECS®- Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- 29,61,1983
RTECS®- Toxicology 1985	RTECS®- Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- 37,51,1985
RTECS®- Toxicology 1987	RTECS®- Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- 44,297,1987
RTECS®- Toxicology 1988	RTECS®- Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- 53,19,1988
RTECS®- Toxicology 1989	RTECS®- Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- 56,239,1989
RTECS®- Toxicology 1990	RTECS®- Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- 63,97,1990
RTECS®- Toxicology 1992	RTECS®- Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- 76,103,1992
RTECS®- Toxicology 1993	RTECS®- Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- 80,217,1993
RTECS®- Toxicology 1994	RTECS®- Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- 89,49,1994
RTECS®- Toxicology 1994	RTECS®- Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- 92,155,1994
RTECS®- Toxicology 1983	RTECS®- Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 28,133,1983
RTECS®- Toxicology 1989	RTECS®- Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 56,239,1989
RTECS®- Veterinary and Human Toxicology 2001	RTECS®- Veterinary and Human Toxicology. (American College of Veterinary and Comparative Toxicology, Publication Office, Comparative Toxicology, Manhattan, KS 66506) V.19- 1977- 43,134,2001
RTECS®- Veterinary and Human Toxicology 2001	RTECS®- Veterinary and Human Toxicology. (American College of Veterinary and Comparative Toxicology, Publication Office, Comparative Toxicology, Manhattan, KS 66506) V.19- 1977- 43,22,2001

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