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National Drinking Water Database


National Drinking Water Database - Chemical Contaminants

2-Hexanone


Status: Unregulated - EPA has not established a maximum legal limit in tapwater for this contaminant.

2-Hexanone is a manufactured chemical formerly used in paint and paint thinner, to make other chemical substances, and to dissolve oils and waxes; it may form in tap water as a result of ozonation.

 
Detected
Found above
health guidelines
Found above
legal limit
States
2
-
-
Water utilities
17
-
-
People Served
97,560
-
-

Health Concerns for 2-Hexanone:


2-Hexanone Exposure by State

Water utilities in 2 states have reported detecting 2-Hexanone in treated tap water since 2004, according to EWG's analysis of water quality data supplied by state water agencies.

StateWater Suppliers with 2-Hexanone contamination
SystemsPopulation
Texas1683,560
New Jersey114,000
Total1797,560

The Most Polluted Communities

17 water utilities reported detecting 2-Hexanone in tap water since 2004, according to EWG's analysis of water quality data supplied by state water agencies

Ranked by highest average 2-Hexanone level

RankSystem Population Served Positive test results of total reported tests Average Level
(Range)
1Ledbetter Wsc
Ledbetter, TX
5281 of 11.2 ppb
(1.2 ppb)
2South River W Dept
South River, NJ
14,0001 of 30.83 ppb
(0 to 2.5 ppb)
3J B Mhp
Houston, TX
751 of 20.8 ppb
(0 to 1.6 ppb)
4Bender Creek Apartments
Austin, TX
3121 of 20.6 ppb
(0 to 1.2 ppb)
5Atascocita Village Mobile Home Park
Humble, TX
7011 of 20.6 ppb
(0 to 1.2 ppb)
6Lazy Acres Mobile Home Park
Baytown, TX
481 of 20.55 ppb
(0 to 1.1 ppb)
7Cedar Bayou Estates
Baytown, TX
601 of 20.55 ppb
(0 to 1.1 ppb)
8Fayette Wsc West
La Grange, TX
2,3901 of 40.53 ppb
(0 to 2.1 ppb)
9B & J Water Co
Bedias, TX
4501 of 10.5 ppb
(0.5 ppb)
10Mill Creek Estates
Magnolia, TX
2101 of 20.5 ppb
(0 to 1 ppb)

Testing Summary for 2-Hexanone

Are tests routinely required for 2-Hexanone by federal law?No
Water suppliers reporting tests for 2-Hexanone (2004-2009):3,513 of 47,576
Average testing rate for water supplier reporting tests (2004-2009):0.4 per year

Developmental/reproductive toxicity

Type of concern: Reference:
Limited evidence of developmental toxicity European Union - Classification & Labelling
Possible human reproductive or developmental toxin Environment Canada Domestic Substance List

Organ system toxicity (non-reproductive)

Type of concern: Reference:
Classified as a high human health priority Environment Canada Domestic Substance List
One or more animal studies show classified as toxic effects at low doses EPA Categorized List of Inert Pesticide Ingredients
One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient) RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J 1986
Classified as not expected to be potentially toxic or harmful Environment Canada Domestic Substance List

Occupational hazards

Type of concern: Reference:
Allowed workplace exposures restricted to low doses European Union - Classification & Labelling
Allowed workplace exposures restricted to moderate doses European Union - Classification & Labelling
Allowed workplace exposures restricted to moderate doses RTECS®- TLV/BEI,2007
Allowed workplace exposures restricted to high doses RTECS®- MSHA STANDARD-air: 3,126,1971
Allowed workplace exposures restricted to high doses RTECS®- OSHA PEL (Gen Indu): 29,1910 1994
Allowed workplace exposures restricted to high doses RTECS®- OSHA PEL (Construc): 29,1926 1994
Allowed workplace exposures restricted to high doses RTECS®- OSHA PEL (Shipyard): 29,1915 1993
Allowed workplace exposures restricted to high doses RTECS®- OSHA PEL (Fed Cont): 41,50-204 1994

Cancer

Type of concern: Reference:
One or more in vitro tests non-mammalian cells show positive mutation results RTECS®- Mutation Research 1994

Irritation (skin, eyes, or lungs)

Type of concern: Reference:
One or more animal studies show skin irritation at moderate doses RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J 1986

Ecotoxicology

Type of concern: Reference:
Not suspected to be an environmental toxin Environment Canada Domestic Substance List

Miscellaneous

Type of concern: Reference:
Occupational hazards related to handling European Union - Classification & Labelling

Persistence and bioaccumulation

Type of concern: Reference:
Not suspected to be persistent Environment Canada Domestic Substance List
Not suspected to be bioaccumulative Environment Canada Domestic Substance List

Neurotoxicity

Type of concern: Reference:
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study National Library of Medicine HazMap



Government, industry, academic studies and classifications

government/industry list/academic study appears on list as classification(s)
European Union - Classification & LabellingHEXAN-2-ONE;;METHYL BUTYL KETONE; BUTYL METHYL KETONE;;METHYL-N-BUTYL KETONE•Flammable
•Limited evidence of reproductive toxicity
•Toxic: danger of serious damage to health by prolonged exposure through inhalation
•Vapours may cause drowsiness and dizziness
Association of Occupational and Environmental ClinicsMETHYL N-BUTYL KETONE• S
European Union - Banned or Restricted in CosmeticsHEXAN-2-ONE•Prohibited in EU cosmetics: must not form part of the composition of cosmetic products
National Library of Medicine HazMap2-HEXANONE•Skin Designation (ACGIH) - Danger of cutaneous absorption (ACGIH): Yes;
•Restricted - Regulations that have banned or restricted the use of the agent: '. . . the sole manufacturer ceased production a number of years ago.' [LaDou, p. 527];
•Neurotoxin: Motor Neuropathy;
•PEL (OSHA) - Permissible exposure limit (OSHA): 100 ppm;
•STEL (ACGIH) - Short-term exposure limits (ACGIH): 10 ppm;
•LC50 - Lethal concentration in 50% of animals tested: 16000 ppm;
•TLV (ACGIH) - Threshold limit value (ACGIH): 5 ppm;
•BEI - Biological Exposure Indices (American Conference of Governmental Industrial Hygiene, ACGIH): 2,5-Hexanedione (free) in urine = 0.4 mg/L end of shift at end of workweek;;FL: 3:
EPA Categorized List of Inert Pesticide IngredientsMETHYL N-BUTYL KETONE•Pesticide inerts of toxicological concern according to EPA (Environmental Protection Agency)
Environment Canada Domestic Substance List2-HEXANONE•This chemical was deemed a high human health priority even though it did not meet the strict criteria of the categorization exercise of CEPA. The chemical was flagged for reproductive concerns.
RTECS®- TLV/BEI,2007HEXAN-2-ONE• occupationally related - ACGIH TLV (human TWA)
RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J 1986HEXAN-2-ONE• sense organ - Primary eye irritant (rabbit )
• skin - Primary skin irritant (rabbit )
RTECS®- MSHA STANDARD-air: 3,126,1971HEXAN-2-ONE• occupationally related - MSHA STANDARD-air (human TWA)
RTECS®- Mutation Research 1994HEXAN-2-ONE• mutagenic - Positive mutation assay: Sex Chromosome Loss and Nondisjunction (Saccharomyces cerevisiae )
RTECS®- OSHA PEL (Construc): 29,1926 1994HEXAN-2-ONE• occupationally related - OSHA PEL (Construc) (human TWA)
RTECS®- OSHA PEL (Fed Cont): 41,50-204 1994HEXAN-2-ONE• occupationally related - OSHA PEL (Fed Cont) (human TWA)
RTECS®- OSHA PEL (Gen Indu): 29,1910 1994HEXAN-2-ONE• occupationally related - OSHA PEL (Gen Indu) (human TWA)
RTECS®- OSHA PEL (Shipyard): 29,1915 1993HEXAN-2-ONE• occupationally related - OSHA PEL (Shipyard) (human TWA)



references

government/industry list/academic study reference
European Union - Classification & LabellingCPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
Association of Occupational and Environmental ClinicsAOEC (Association of Occupational and Environmental Clinics). 2009. AEOC exposures codes and asthmagen designation.
European Union - Banned or Restricted in CosmeticsEC (European Commission of the European Union). 1999-2006. Enterprise Directorate-General Pharmaceuticals and Cosmetics. The rules governing cosmetic products in the European Union, Volume 1, "Cosmetics legislation."
National Library of Medicine HazMapNLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
EPA Categorized List of Inert Pesticide IngredientsEPA (U.S. Environmental Protection Agency). 1987 & 2005. Office of Pesticide Programs. Inert (other) Pesticide Ingredients in Pesticide Products - Categorized List of Inert (other) Pesticide Ingredients.
Environment Canada Domestic Substance ListEC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
RTECS®- TLV/BEI,2007RTECS®- TLV/BEI,2007
RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J 1986RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 -,283,1986
RTECS®- MSHA STANDARD-air: 3,126,1971RTECS®- MSHA STANDARD-air: 3,126,1971
RTECS®- Mutation Research 1994RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 341,83,1994
RTECS®- OSHA PEL (Construc): 29,1926 1994RTECS®- OSHA PEL (Construc): 29,1926.55,1994
RTECS®- OSHA PEL (Fed Cont): 41,50-204 1994RTECS®- OSHA PEL (Fed Cont): 41,50-204.50,1994
RTECS®- OSHA PEL (Gen Indu): 29,1910 1994RTECS®- OSHA PEL (Gen Indu): 29,1910.1000,1994
RTECS®- OSHA PEL (Shipyard): 29,1915 1993RTECS®- OSHA PEL (Shipyard): 29,1915.1000,1993

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