National Drinking Water Database
National Drinking Water Database - Chemical Contaminants
1,2-Dibromo-3-chloropropane (DBCP)
Status: Regulated - EPA has established a maximum legal limit in tapwater for this contaminant.
1,2-Dibromo-3-chloropropane is a persistent pesticide and groundwater contaminant associated with male sterility and severe reproductive toxicity; historically used as a soil fumigant on bananas and pineapples; banned by EPA in early 1980s. [read more]
Detected |
Found above health guidelines |
Found above legal limit |
|
|---|---|---|---|
| States | 18 |
18 |
6 |
| Water utilities | 191 |
191 |
48 |
| People Served | 7,152,789 |
7,152,789 |
1,860,799 |
Health Concerns for 1,2-Dibromo-3-chloropropane (DBCP):
- Developmental/reproductive toxicity
- Cancer
- Endocrine disruption
- Organ system toxicity (non-reproductive)
- Occupational hazards
- Persistence and bioaccumulation
- Irritation (skin, eyes, or lungs)
- Ecotoxicology
1,2-Dibromo-3-chloropropane (DBCP) Exposure by State
Water utilities in 18 states have reported detecting 1,2-Dibromo-3-chloropropane (DBCP) in treated tap water since 2004, according to EWG's analysis of water quality data supplied by state water agencies.
| State | Water Suppliers with 1,2-Dibromo-3-chloropropane (DBCP) contamination | Water suppliers reporting 1,2-Dibromo-3-chloropropane (DBCP) above health-based limits | ||
|---|---|---|---|---|
| Systems | Population | Systems | Population | |
| California | 132 | 4,060,479 | 132 | 4,060,479 |
| Florida | 12 | 1,262,030 | 12 | 1,262,030 |
| Arizona | 9 | 704,792 | 9 | 704,792 |
| Nebraska | 1 | 506,420 | 1 | 506,420 |
| Delaware | 3 | 203,522 | 3 | 203,522 |
| New Jersey | 1 | 123,174 | 1 | 123,174 |
| Hawaii | 4 | 62,198 | 4 | 62,198 |
| Massachusetts | 1 | 42,375 | 1 | 42,375 |
| North Carolina | 4 | 36,299 | 4 | 36,299 |
| Kentucky | 1 | 34,650 | 1 | 34,650 |
| New York | 8 | 30,850 | 8 | 30,850 |
| Arkansas | 4 | 29,405 | 4 | 29,405 |
| Maryland | 1 | 25,000 | 1 | 25,000 |
| Illinois | 4 | 20,372 | 4 | 20,372 |
| Connecticut | 2 | 10,432 | 2 | 10,432 |
| Wisconsin | 2 | 700 | 2 | 700 |
| Virginia | 1 | 60 | 1 | 60 |
| Oregon | 1 | 31 | 1 | 31 |
| Total | 191 | 7,152,789 | 191 | 7,152,789 |
The Most Polluted Communities
191 water utilities reported detecting 1,2-Dibromo-3-chloropropane (DBCP) in tap water since 2004, according to EWG's analysis of water quality data supplied by state water agencies
Ranked by highest average 1,2-Dibromo-3-chloropropane (DBCP) level
| Rank | System | Population Served | Positive test results of total reported tests | Average Level (Range) |
|---|---|---|---|---|
| 1 | Ridgedale Court Calcium, NY | 35 | 1 of 1 | 0.6 ppb (0.6 ppb) |
| 2 | Edgewood Trailer Park Evans Mills, NY | 120 | 1 of 1 | 0.5 ppb (0.5 ppb) |
| 3 | Turin Village Turin, NY | 350 | 2 of 2 | 0.5 ppb (0.5 ppb) |
| 4 | Deferiet Village Deferiet, NY | 300 | 1 of 1 | 0.5 ppb (0.5 ppb) |
| 5 | Pamelia Town WD 5 Watertown, NY | 1,000 | 1 of 1 | 0.5 ppb (0.5 ppb) |
| 6 | Lyons Falls Village Lyons Falls, NY | 850 | 1 of 1 | 0.5 ppb (0.5 ppb) |
| 7 | Lake Trailer Court Calcium, NY | 195 | 1 of 1 | 0.5 ppb (0.5 ppb) |
| 8 | Son Shine Properties Edison, CA | 250 | 4 of 4 | 0.33 ppb (0.2 to 0.45 ppb) |
| 9 | Family Tree Farms Reedley, CA | 25 | 12 of 13 | 0.27 ppb (0 to 0.39 ppb) |
| 10 | Happy Acres Merced, CA | 24 | 5 of 8 | 0.26 ppb (0 to 0.6 ppb) |
Health Based Limits for 1,2-Dibromo-3-chloropropane (DBCP)
| Standard | Description | Level |
|---|---|---|
| Maximum Contaminant Limit Goal (MCLG) | A non-enforceable health goal that is set at a level at which no known or anticipated adverse effect on the health of persons occurs and which allows an adequate margin of safety. Source: U.S. Environmental Protection Agency. | 0 ppb |
| California Public Health Goals | Defined by the State of California Office of Environmental Health Hazard Assessment (OEHHA) as the level of contaminant that is allowed in drinking water. For acutely toxic substances, levels are set at which scientific evidence indicates that no known or anticipated adverse effects on health will occur, plus an adequate margin-of safety. PHGs for carcinogens or other substances which can cause chronic disease shall be based solely on health effects without regard to cost impacts and shall be set at levels which OEHHA has determined do not pose any significant risk to health. | <0.01 ppb |
| One in one million (10-6) Cancer Risk | The concentration of a chemical in drinking water corresponding to an excess estimated lifetime cancer risk of 1 in 1,000,000. Source: U.S. Environmental Protection Agency. | 0.03 ppb |
| Maximum Contaminant Limit (MCL) | The enforceable standard which defines the highest level of a contaminant that is allowed in drinking water. MCLs are set as close to health-based limits (Maximum Contaminant Level Goals, or MCLGs) as feasible using the best available analytical and treatment technologies and taking cost into consideration. Source: U.S. Environmental Protection Agency. | 0.2 ppb |
| One in ten thousand (10-4) Cancer Risk | The concentration of a chemical in drinking water corresponding to an excess estimated lifetime cancer risk of 1 in 10,000. Source: U.S. Environmental Protection Agency. | 3 ppb |
| Children's health-based limit for 10-day exposure | Concentration of a chemical in drinking water that is not expected to cause any adverse, noncarcinogenic effects for up to ten days of exposure. The Ten-Day health-based limit (or Health Advisory, HA) is typically set to protect a 10-kg child consuming 1 liter of water per day. Source: U.S. Environmental Protection Agency. | 50 ppb |
| Children's health-based limit for 1-day exposure | Concentration of a chemical in drinking water that is not expected to cause any adverse, noncarcinogenic health effects for up to one day of exposure. The One-Day health-based limit (or Health Advisory, HA) is typically set to protect a 10-kg child consuming 1 liter of water per day. Source: U.S. Environmental Protection Agency. | 200 ppb |
Testing Summary for 1,2-Dibromo-3-chloropropane (DBCP)
| Are tests routinely required for 1,2-Dibromo-3-chloropropane (DBCP) by federal law? | Yes |
| Water suppliers reporting tests for 1,2-Dibromo-3-chloropropane (DBCP) (2004-2009): | 22,231 of 47,576 |
| Average testing rate for water supplier reporting tests (2004-2009): | 0.5 per year |
Violation Summary for 1,2-Dibromo-3-chloropropane (DBCP)
Data from the U.S. Environmental Protection Agency includes the following violations of federal standards for 1,2-Dibromo-3-chloropropane (DBCP) since 2004
| Maximum Contaminant Level Exceedance Violations | 4 |
| Monitoring Violations | 1,295 |
| Reporting Violations | 0 |
Developmental/reproductive toxicity
| Type of concern: | Reference: |
| Known human reproductive toxicant | European Union - Classification & Labelling |
| Possible human developmental toxicant | California EPA Proposition 65 |
| Human reproductive toxicant - strong evidence | Proposition 65 List of Carcinogens |
| Limited evidence of reproductive toxicity | European Union - Classification & Labelling |
| Limited evidence of reproductive toxicity | National Library of Medicine HazMap |
| Limited evidence of developmental toxicity | US EPA, 9204 |
Cancer
| Type of concern: | Reference: |
| Possible human carcinogen | European Union - Classification & Labelling |
| Possible human carcinogen | NTP Report on Carcinogens, 11th Edition |
| Possible human carcinogen | NTP - Tumor Induction in Mammary Gland |
| Cancer - strong evidence | Proposition 65 List of Carcinogens |
| Limited evidence of carcinogenicity | Int'l Agency for Research on Cancer (IARC) - Carcinogens |
| Limited evidence of carcinogenicity | NIOSH Occupational Carcinogens |
| Possible mutagen | European Union - Classification & Labelling |
| One or more human case studies show possible cancer findings | NTP - Tumor Induction in Mammary Gland |
| Cancer - limited evidence | Silent Spring's Mammary Carcinogens Reviews Database |
| One or more in vitro tests on mammalian cells show positive mutation results | RTECS®- Mutation Research 1982 |
| One or more in vitro tests on mammalian cells show positive mutation results | RTECS®- Mutation Research 1990 |
| One or more in vitro tests on mammalian cells show positive mutation results | RTECS®- Cell Biology and Toxicology 1985 |
| One or more in vitro tests on mammalian cells show positive mutation results | RTECS®- Chemical Research in Toxicology 1991 |
| One or more in vitro tests on mammalian cells show positive mutation results | RTECS®- Carcinogenesis (London) 1989 |
| One or more in vitro tests on mammalian cells show positive mutation results | RTECS®- Mutation Research 1988 |
| One or more in vitro tests on mammalian cells show positive mutation results | RTECS®- Toxicology and Applied Pharmacology 1979 |
| One or more in vitro tests on mammalian cells show positive mutation results | RTECS®- Mutation Research 1980 |
| One or more in vitro tests on mammalian cells show positive mutation results | RTECS®- Mutation Research 1997 |
| One or more in vitro tests on mammalian cells show positive mutation results | RTECS®- Cell Biology and Toxicology 1987 |
| One or more in vitro tests on mammalian cells show positive mutation results | RTECS®- Mutation Research 1986 |
| One or more in vitro tests on mammalian cells show positive mutation results | RTECS®- Mutation Research 1979 |
| One or more in vitro tests on mammalian cells show positive mutation results | RTECS®- Mutation Research 1998 |
| One or more in vitro tests on mammalian cells show positive mutation results | RTECS®- Science 1987 |
| One or more in vitro tests on mammalian cells show positive mutation results | RTECS®- Mutation Research 1993 |
| One or more in vitro tests on mammalian cells show positive mutation results | RTECS®- Fundamental and Applied Toxicology 1986 |
| One or more in vitro tests on mammalian cells show positive mutation results | RTECS®- Toxicology 1989 |
| One or more in vitro tests on mammalian cells show positive mutation results | RTECS®- Gigiena i Sanitariya 1993 |
| One or more in vitro tests non-mammalian cells show positive mutation results | RTECS®- Science of the Total Environment 1979 |
| One or more in vitro tests non-mammalian cells show positive mutation results | RTECS®- Environmental Mutagenesis 1985 |
| One or more in vitro tests non-mammalian cells show positive mutation results | RTECS®- Mutation Research 1984 |
| One or more in vitro tests non-mammalian cells show positive mutation results | RTECS®- Bulletin of Environmental Contamination and Toxicology 1975 |
| One or more in vitro tests non-mammalian cells show positive mutation results | RTECS®- Microbiology Series 1981 |
| One or more in vitro tests non-mammalian cells show positive mutation results | RTECS®- Environmental Mutagenesis 1982 |
| One or more in vitro tests non-mammalian cells show positive mutation results | RTECS®- Huanjing Kexue 1984 |
| One or more in vitro tests non-mammalian cells show positive mutation results | RTECS®- Environmental and Molecular Mutagenesis 2004 |
Endocrine disruption
| Type of concern: | Reference: |
| Human disruptor - strong evidence | European Commission on Endocrine Disruption |
| Limited evidence of endocrine disruption | Illinois EPA, 1997 |
| endocrine - weight of evidence unknown/unassessed/unreview: published lit review or major tox study | Illinois EPA Chemicals Associated with Endocrine System |
Organ system toxicity (non-reproductive)
| Type of concern: | Reference: |
| Known human respiratory toxicant | EPA Hazardous Air Pollutants |
| Classified as toxic or harmful | European Union - Classification & Labelling |
| Limited evidence of gastrointestinal or liver toxicity | National Library of Medicine HazMap |
| Limited evidence of respiratory toxicity | US EPA, Air Risk Information Support Center |
| Limited evidence of gastrointestinal or liver toxicity | US EPA, Air Risk Information Support Center |
| Limited evidence of kidney toxicity | Klaassen, C, 1996 |
| Limited evidence of sense organ toxicity | Lock, E, 1992 |
| One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient) | EPA Toxic Release Inventory PBTs |
| One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient) | RTECS®- Toxicology and Applied Pharmacology 1961 |
| reproductive - weight of evidence unknown/unassessed/unreview: published lit review or major tox study | National Library of Medicine HazMap |
Occupational hazards
| Type of concern: | Reference: |
| Allowed workplace exposures restricted to low doses | European Union - Classification & Labelling |
Persistence and bioaccumulation
| Type of concern: | Reference: |
| Persistent, bioaccumulative in wildlife | Canada PBTs - Accelerated Reduction/Elimination of Toxics (ARET) |
Irritation (skin, eyes, or lungs)
| Type of concern: | Reference: |
| One or more animal studies show skin irritation at very low doses | RTECS®- Toxicology and Applied Pharmacology 1961 |
Ecotoxicology
| Type of concern: | Reference: |
| Wildlife and environmental toxicity | European Union - Classification & Labelling |
| Wildlife and environmental toxicity | Illinois EPA Chemicals Associated with Endocrine System |
Government, industry, academic studies and classifications
| government/industry list/academic study | appears on list as | classification(s) |
| European Union - Classification & Labelling | 1,2-DIBROMO-3-CHLOROPROPANE | •May cause cancer •May cause cancer •May cause heritable genetic damage •Known reproductive toxin •May impair fertility •Toxic •Toxic if swallowed •Harmful •Harmful: danger of serious damage to health by prolonged exposure through inhalation and if swallowed •Harmful to aquatic organisms |
| Illinois EPA Chemicals Associated with Endocrine System | 1,2-DIBROMO-3-CHLOROPROPANE | •EPA: known endocrine disruptor |
| European Commission on Endocrine Disruption | DIBROMOCHLOROPROPANE (DBCP) | HH-CAT1;WF-CAT3b |
| European Union - Banned or Restricted in Cosmetics | 1,2-DIBROMO-3-CHLOROPROPANE | •Prohibited in EU cosmetics: must not form part of the composition of cosmetic products |
| EPA Hazardous Air Pollutants | 1,2-DIBROMO-3-CHLOROPROPANE | •Hazardous air pollutant under Clean Air Act |
| National Library of Medicine HazMap | 1,2-DIBROMO-3-CHLOROPROPANE | •Reproductive Toxin - A chemical that is toxic to the reproductive system, including defects in the progeny and injury to male and female reproductive function: Yes; •Restricted - Regulations that have banned or restricted the use of the agent: All uses except on pineapple plantations in Hawaii canceled in 1979; use on pineapples cancelled in 1985; See 29CFR1910.1044;; •Hepatotoxin: Hepatotoxin, Secondary; •PEL (OSHA) - Permissible exposure limit (OSHA): 0.001 ppm; •IARC Carcinogen - International Agency for Research on Cancer; classifies chemicals as established (1), probable (2a), or possible (2b) human carcinogens: Possible Carcinogen; |
| Int'l Agency for Research on Cancer (IARC) - Carcinogens | 1,2-DIBROMO-3-CHLOROPROPANE | •IARC Group 2B: possible human carcinogen (International Agency for Research on Carcinogens) |
| NIOSH Occupational Carcinogens | 1,2-DIBROMO-3-CHLOROPROPANE (DBCP) | •Potential occupational carcinogen according to NIOSH (National Institute for Occupational Safety and Health) |
| NTP Report on Carcinogens, 11th Edition | 1,2-DIBROMO-3-CHLOROPROPANE | •Reasonably anticipated to be a human carcinogen (National Toxicology Program classification) |
| NTP - Tumor Induction in Mammary Gland | 1,2-DIBROMO-3-CHLOROPROPANE | •Induces mammary tumors (National Toxicology Program classification) |
| Canada PBTs - Accelerated Reduction/Elimination of Toxics (ARET) | 1,2-DIBROMO-3-CHLORO-PROPANE | •Toxicant of concern under Canada's Accelerated Reduction/Elimination of Toxics program - targeted for elimination or reduction |
| EPA Toxic Release Inventory PBTs | 1,2-DIBROMO-3-CHLORO-PROPANE | •Toxic, U.S. Environmental Protection Agency Toxics Release Inventory programs |
| California EPA Proposition 65 | 1,2-DIBROMO-3-CHLOROPROPANE (DBCP) | •Reproductive toxin, male: California Proposition 65 |
| US EPA, Air Risk Information Support Center | 1,2-DIBROMO-3-CHLOROPROPANE (DBCP) | •Respiratory toxicity hazards: suspected |
| US EPA, Air Risk Information Support Center | 1,2-DIBROMO-3-CHLOROPROPANE (DBCP) | •Gastrointestinal or liver toxicity hazards: suspected |
| US EPA, 9204 | 1,2-DIBROMO-3-CHLOROPROPANE (DBCP) | •Developmental toxicity hazards: suspected |
| Illinois EPA, 1997 | 1,2-DIBROMO-3-CHLOROPROPANE (DBCP) | •Endocrine toxicity hazards: suspected |
| Klaassen, C, 1996 | 1,2-DIBROMO-3-CHLOROPROPANE (DBCP) | •Kidney toxicity hazards: suspected |
| Lock, E, 1992 | 1,2-DIBROMO-3-CHLOROPROPANE (DBCP) | •Skin or sense organ toxicity hazards: suspected |
| Proposition 65 List of Carcinogens | 1,2-DIBROMO-3-CHLOROPROPANE (DBCP) | •Cancer hazards: recognized |
| Proposition 65 List of Carcinogens | 1,2-DIBROMO-3-CHLOROPROPANE (DBCP) | •Reproductive toxicity hazards: recognized |
| Silent Spring's Mammary Carcinogens Reviews Database | 1,2-DIBROMO-3-CHLOROPROPANE | •Chemicals Shown to Cause Mammary Gland Tumors in Animal Studies |
| RTECS®- Bulletin of Environmental Contamination and Toxicology 1975 | 1,2-DIBROMO-3-CHLOROPROPANE | • mutagenic - Positive mutation assay: DNA repair (Escherichia coli ) |
| RTECS®- Carcinogenesis (London) 1989 | 1,2-DIBROMO-3-CHLOROPROPANE | • mutagenic - Positive mutation assay: DNA Damage (rat lvr) |
| RTECS®- Cell Biology and Toxicology 1985 | 1,2-DIBROMO-3-CHLOROPROPANE | • mutagenic - Positive mutation assay: DNA Damage (rat ipr) |
| RTECS®- Cell Biology and Toxicology 1987 | 1,2-DIBROMO-3-CHLOROPROPANE | • mutagenic - Positive mutation assay: Mutation in Micro-organism (mouse lym) • mutagenic - Positive mutation assay: Morphological Transform (hamster emb) |
| RTECS®- Chemical Research in Toxicology 1991 | 1,2-DIBROMO-3-CHLOROPROPANE | • mutagenic - Positive mutation assay: DNA Damage (rat ipr) |
| RTECS®- Environmental and Molecular Mutagenesis 2004 | 1,2-DIBROMO-3-CHLOROPROPANE | • mutagenic - Positive mutation assay: Mutation in Micro-organism (Salmonella typhimurium ) |
| RTECS®- Environmental Mutagenesis 1982 | 1,2-DIBROMO-3-CHLOROPROPANE | • mutagenic - Positive mutation assay: Sex Chromosome Loss and Nondisjunction (Drosophila melanogaster ihl) |
| RTECS®- Environmental Mutagenesis 1985 | 1,2-DIBROMO-3-CHLOROPROPANE | • mutagenic - Positive mutation assay: Mutation in Micro-organism (Salmonella typhimurium ) |
| RTECS®- Environmental Mutagenesis 1985 | 1,2-DIBROMO-3-CHLOROPROPANE | • mutagenic - Positive mutation assay: Heritable Translocation Test (Drosophila melanogaster orl) |
| RTECS®- Fundamental and Applied Toxicology 1986 | 1,2-DIBROMO-3-CHLOROPROPANE | • mutagenic - Positive mutation assay: sperm (rabbit orl) |
| RTECS®- Gigiena i Sanitariya 1993 | 1,2-DIBROMO-3-CHLOROPROPANE | • mutagenic - Positive mutation assay: Micronucleus test (rat orl) |
| RTECS®- Huanjing Kexue 1984 | 1,2-DIBROMO-3-CHLOROPROPANE | • mutagenic - Positive mutation assay: Sex Chromosome Loss and Nondisjunction (Drosophila melanogaster orl) |
| RTECS®- Microbiology Series 1981 | 1,2-DIBROMO-3-CHLOROPROPANE | • mutagenic - Positive mutation assay: Mutation in Micro-organism (Bacillus subtilis ) |
| RTECS®- Mutation Research 1984 | 1,2-DIBROMO-3-CHLOROPROPANE | • mutagenic - Positive mutation assay: other mutation test systems (Escherichia coli ) |
| RTECS®- Mutation Research 1986 | 1,2-DIBROMO-3-CHLOROPROPANE | • mutagenic - Positive mutation assay: (mouse ipr) |
| RTECS®- Mutation Research 1988 | 1,2-DIBROMO-3-CHLOROPROPANE | • mutagenic - Positive mutation assay: Unscheduled DNA Synthesis (rat ipr) |
| RTECS®- Mutation Research 1990 | 1,2-DIBROMO-3-CHLOROPROPANE | • mutagenic - Positive mutation assay: Micronucleus test (rat orl) |
| RTECS®- Mutation Research 1993 | 1,2-DIBROMO-3-CHLOROPROPANE | • mutagenic - Positive mutation assay: DNA Damage (rabbit oth) |
| RTECS®- Mutation Research 1997 | 1,2-DIBROMO-3-CHLOROPROPANE | • mutagenic - Positive mutation assay: Micronucleus test (mouse ipr) |
| RTECS®- Mutation Research 1998 | 1,2-DIBROMO-3-CHLOROPROPANE | • mutagenic - Positive mutation assay: DNA Damage (mouse ipr) |
| RTECS®- Mutation Research 1979 | 1,2-DIBROMO-3-CHLOROPROPANE | • mutagenic - Positive mutation assay: Unscheduled DNA Synthesis (mouse ipr) |
| RTECS®- Mutation Research 1980 | 1,2-DIBROMO-3-CHLOROPROPANE | • mutagenic - Positive mutation assay: Dominant Lethal Strain (rat orl) |
| RTECS®- Mutation Research 1980 | 1,2-DIBROMO-3-CHLOROPROPANE | • mutagenic - Positive mutation assay: Cytogenetic Analysis (hamster lng) • mutagenic - Positive mutation assay: Sister Chromatid Exchange (hamster lng) |
| RTECS®- Mutation Research 1982 | 1,2-DIBROMO-3-CHLOROPROPANE | • mutagenic - Positive mutation assay: DNA Inhibition ( human hla) |
| RTECS®- Science of the Total Environment 1979 | 1,2-DIBROMO-3-CHLOROPROPANE | • mutagenic - Positive mutation assay: Mutation in Micro-organism (Salmonella typhimurium ) |
| RTECS®- Science 1987 | 1,2-DIBROMO-3-CHLOROPROPANE | • mutagenic - Positive mutation assay: Cytogenetic Analysis (hamster ovr) • mutagenic - Positive mutation assay: Mutation in Mammalian Somatic Cells (mouse lym) • mutagenic - Positive mutation assay: Sister Chromatid Exchange (hamster ovr) |
| RTECS®- Toxicology and Applied Pharmacology 1961 | 1,2-DIBROMO-3-CHLOROPROPANE | • sense organ - Primary eye irritant (rabbit ) • skin - Primary skin irritant (rabbit ) |
| RTECS®- Toxicology and Applied Pharmacology 1979 | 1,2-DIBROMO-3-CHLOROPROPANE | • mutagenic - Positive mutation assay: Cytogenetic Analysis (rat orl) • mutagenic - Positive mutation assay: sperm (rat orl) |
| RTECS®- Toxicology 1989 | 1,2-DIBROMO-3-CHLOROPROPANE | • mutagenic - Positive mutation assay: DNA Damage (guinea pig ipr) |
references
| government/industry list/academic study | reference |
| European Union - Classification & Labelling | CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP. |
| Illinois EPA Chemicals Associated with Endocrine System | Illinois EPA (Illinois Environmental Protection Agency). 2000. Preliminary list of chemicals associated with endocrine system effects in animals and humans (*) or in vitro (+). In EPA (U.S. Environmental Protection Agency) 2000. Handbook for Non-Cancer Health Effects Valuation, Appendix C. |
| European Commission on Endocrine Disruption | EU (European Union)- Strategy for Endocrine Disrupters 2007. Commision on endocrin disruption requested by the European Parliament in 1998. |
| European Union - Banned or Restricted in Cosmetics | EC (European Commission of the European Union). 1999-2006. Enterprise Directorate-General Pharmaceuticals and Cosmetics. The rules governing cosmetic products in the European Union, Volume 1, "Cosmetics legislation." |
| EPA Hazardous Air Pollutants | EPA (U.S. Environmental Protection Agency). 2005. Office of Air. The 112(b)1 Hazardous Air Pollutants List (as modified). Last modified: 12 Dec 2005. |
| National Library of Medicine HazMap | NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents. |
| Int'l Agency for Research on Cancer (IARC) - Carcinogens | IARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures). |
| NIOSH Occupational Carcinogens | NIOSH (National Institute for Occupational Safety and Health). 2006. NIOSH Carcinogens List (Potential occupational carcinogens). http://www.cdc.gov/niosh/npotocca.html. |
| NTP Report on Carcinogens, 11th Edition | NTP (National Toxicology Program). 2005. Report on Carcinogens, Eleventh Edition; U.S. Department of Health and Human Services, Public Health Service, National Toxicology Program. |
| NTP - Tumor Induction in Mammary Gland | NTP (National Toxicology Program) 2006. Chemicals Associated with Site-Specific Tumor Induction in Mammary Gland. |
| Canada PBTs - Accelerated Reduction/Elimination of Toxics (ARET) | EC (Environment Canada). 1994. Accelerated Reduction/Elimination of Toxics (ARET). ARET substance list of persistent, bioaccumulative and toxic chemicals. |
| EPA Toxic Release Inventory PBTs | EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule. |
| California EPA Proposition 65 | California EPA (California Environmental Protection Agency). 9/2008. Office of Environmental Health Hazard Assessment. Safe Drinking Water and Toxic Enforcement Act of 1986. Chemicals known to the State to cause cancer or reproductive toxicity. |
| Scorecard.org Toxicity Information | US EPA, Air Risk Information Support Center. Health Effects Notebook for Hazardous Air Pollutants. http://www.epa.gov/ttnatw01/hlthef/hapindex.html, National Institute for Occupational Safety and Health's Registry of Toxic Effects of Chemical Substances. See Environmental Defense's Suspect Hazard Identification documentation. |
| Scorecard.org Toxicity Information | US EPA, Air Risk Information Support Center. Health Effects Notebook for Hazardous Air Pollutants. http://www.epa.gov/ttnatw01/hlthef/hapindex.html, National Institute for Occupational Safety and Health's Registry of Toxic Effects of Chemical Substances. See Environmental Defense's Suspect Hazard Identification documentation. |
| Scorecard.org Toxicity Information | US EPA. Roadmaps to Sources of Information on Chemicals Listed in the Emergency Planning Community and Community Right-to-Know Act (Also Known as SARA Title 3), Section 313 Toxic Release Inventory (for Microcomputers). (Report Number EPADFDK92040). 1991. Data file distributed in 2 diskettes by Office of Pollution, Prevention, and Toxics, Environmental Protection Agency, Washington, DC. NOTE: Datasource no longer being maintained by EPA; not currently available online. |
| Scorecard.org Toxicity Information | Illinois EPA. Endocrine Disruptors Strategy. 1997. (Table 1: Preliminary List of Chemicals Associated with Endocrine System Effects in Animals and Humans or In Vitro). http://www.nihs.go.jp/hse/environ/illiepatable.htm, Japanese National Institute of Health Sciences. Lists of Paradigmatic Chemicals. http://www.nihs.go.jp/hse/endocrine-e/paradigm/paradigm.html, Keith, L.H. (ed.). Environmental Endocrine Disruptors. John Wiley & Sons, NY. 1997. http://www.wileyeurope.com/cda/product/0,,0471191450%7Cdesc%7C3037,00.html |
| Scorecard.org Toxicity Information | Klaassen, C., M. Amdur and J. Doull (eds.). Casarett and Doull's Toxicology. The Basic Science of Poisons, 5th Ed. Pergamon Press, NY. 1996. |
| Scorecard.org Toxicity Information | Lock, E.A., and E. Harpur. Toxicology of Sensory System: A Perspective. Human and Experimental Toxicology. 11(6): 442-448. 1992. (Table 1: Chemicals that induce olfactory lesions in experimental animals by either inhalation and/or non-inhalation routes)., National Institute for Occupational Safety and Health's Registry of Toxic Effects of Chemical Substances. See Environmental Defense's Suspect Hazard Identification documentation. |
| Scorecard.org Toxicity Information | Proposition 65 List of Carcinogens (July 2004) can be obtained from http://www.oehha.ca.gov/prop65/prop65_list/Newlist.html. |
| Scorecard.org Toxicity Information | Proposition 65 List of Carcinogens (July 2004) can be obtained from http://www.oehha.ca.gov/prop65/prop65_list/Newlist.html. |
| Silent Spring's Mammary Carcinogens Reviews Database | Rudel RA, KR Attfield, JN Schifano and JG Brody. Chemicals Causing Mammary Gland Tumors in Animals Signal New Directions for Epidemiology, Chemicals Testing, and Risk Assessment for Breast Cancer Prevention. CANCER Supplement. 2007 Jun 15;109(12):2635-2666. |
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| RTECS®- Huanjing Kexue 1984 | RTECS®- Huanjing Kexue. Environmental Sciences. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) 5(5),7,1984 |
| RTECS®- Microbiology Series 1981 | RTECS®- Microbiology Series. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 5,93,1981 |
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