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PESTICIDES

Cancer

Concern Reference
Known human carcinogenProposition 65 List of Carcinogens (2013) can be obtained from http://www
Cancer - strong evidenceNAS (National Academy of Sciences)

Use restrictions

Concern Reference
Violation of government restrictions - Banned or found unsafe for use in cosmetics
Recommendation to minimize use in cosmetics - CIR (Cosmetic Ingredient Review)

Neurotoxicity

Concern Reference
Strong evidence of human neurotoxicityNAS (National Academy of Sciences)
One or more human case studies show significant effectsRauh V, Arunajadai S, Horton M, Perera F, Hoepner L, Barr DB, et al

Allergies/immunotoxicity

Concern Reference
Human Immune System toxicant or allergen - strong evidenceNAS (National Academy of Sciences)

Developmental/reproductive toxicity

Concern Reference
One or more animal studies show developmental effects at very low dosesBlystone, Chad R

Data gaps

Concern Reference
25,628 studies in PubMed science library may include information on the toxicity of this chemical see search results ->NLM PubMed

Data Sources

Blystone, Chad R., et al. "Iprodione delays male rat pubertal development, reduces serum testosterone levels, and decreases ex vivo testicular testosterone production." Toxicology letters 174.1 (2007): 74-81.
CIR (Cosmetic Ingredient Review). 2007. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
Federal Food, Drug, and Cosmetic Act (FD&C Act), FIFRA & Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA)
NAS (National Academy of Sciences). 1993. Pesticides in the Diets of Infants and Children. National Academy of Sciences, Commission of Life Science. Washington, DC. http://www.nap.edu/catalog.php?record_id=2126
NAS (National Academy of Sciences). 1993. Pesticides in the Diets of Infants and Children. National Academy of Sciences, Commission of Life Science. Washington, DC. http://www.nap.edu/catalog.php?record_id=2126
NAS (National Academy of Sciences). 1993. Pesticides in the Diets of Infants and Children. National Academy of Sciences, Commission of Life Science. Washington, DC. http://www.nap.edu/catalog.php?record_id=2126
NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
Proposition 65 List of Carcinogens (2013) can be obtained from http://www.oehha.ca.gov/prop65/prop65_list/Newlist.html.
Rauh V, Arunajadai S, Horton M, Perera F, Hoepner L, Barr DB, et al. 2011. 7-Year Neurodevelopmental Scores and Prenatal Exposure to Chlorpyrifos, a Common Agricultural Pesticide. Environ Health Perspect doi: 10.1289/ehp.1003160.

About the Skin Deep® ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

About EWG VERIFIED™

Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIEDTM on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Learn more | Legal Disclaimer