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Health Concerns of the Ingredient:
Overall Hazard
Developmental &
reproductive toxicity
Allergies & immunotoxicity
Other HIGH concerns: Contamination concerns; Other MODERATE concerns: Organ system toxicity (non-reproductive); Other LOW concerns: Data gaps, Endocrine disruption

About PLACENTAL PROTEIN: Placental Protein is a mixture of proteins derived from animal placentas.

This ingredient may be derived from animals. From PETA's Caring Consumer: Contains waste matter eliminated by the fetus. Derived from the uterus of slaughtered animals. Animal placenta is widely used in skin creams, shampoos, masks, etc. Alternatives: kelp, olive oil, wheat ... read more

Function(s): Hair Conditioning Agent; Skin-Conditioning Agent - Miscellaneous; HUMECTANT


Use restrictions

Concern Reference
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmeticsCanada - Prohibited and Restricted Cosmetics Ingredients

Organ system toxicity (non-reproductive)

Concern Reference
Potential risk of infectious disease - Must be free of detectable pathogenic viruses or infectious agentsCosmetic Ingredient Review Assessments

Endocrine disruption

Concern Reference
One or more studies show weak endocrine disruptionTiwary, C
endocrine - weight of evidence unknown/unassessed/unreview: published lit review or major tox studyCosmetic Ingredient Review Assessments

Data gaps

Concern Reference
Insufficient data to determine safetyCosmetic Ingredient Review Assessments
836 studies in PubMed science library may include information on the toxicity of this chemical see search results ->NLM PubMed

Contamination concerns

Impurity Score
Data: Fair
Data: Fair
Data: Fair

Data Sources

CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
FDA, 2006. "GUIDE TO INSPECTIONS OF COSMETIC PRODUCT MANUFACTURERS," U.S. Food and Drug Administration, Accessed on May 14th, 2007 at: http://www.fda.gov/ora/inspect_ref/igs/cosmet.html.
FDA, 2006. "GUIDE TO INSPECTIONS OF COSMETIC PRODUCT MANUFACTURERS," U.S. Food and Drug Administration, Accessed on May 14th, 2007 at: http://www.fda.gov/ora/inspect_ref/igs/cosmet.html.
Health Canada. 2007. List of Prohibited and Restricted Cosmetic Ingredients. Canada's Cosmetic Ingredient Hotlist. March 2007.
NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
Tiwary, C. M. (1998). "Premature sexual development in children following the use of estrogen- or placenta-containing hair products." Clin Pediatr (Phila) 37(12): 733-9.

About the Skin Deep® ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer


Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIEDTM on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED member companies that help to support the important work we do. Learn more | Legal Disclaimer