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P-CHLORO-M-CRESOL


image source: PubChem
Health Concerns of the Ingredient:
Overall Hazard
 
 
Cancer
 
 
Developmental &
reproductive toxicity
 
 
 

About P-CHLORO-M-CRESOL: p-Chloro-m-Cresol is a substituted phenol.

Function(s): Cosmetic Biocide; Preservative

Synonym(s): p-CHLORO-m-CRESOL, 1-CHLORO-2-METHYL-4-HYDROXYBENZENE; 2-CHLORO-5-HYDROXYTOLUENE; 4-CHLORO-3-METHYL PHENOL; 4-CHLORO-3-METHYL- PHENOL; 4-CHLORO-M-CRESOL; CHLOROCRESOL; CHLOROMETHYLPHENOL; PARACHLOROMETACRESOL; PHENOL, 4-CHLORO-3-METHYL-; PHENOL, 4CHLORO3METHYL; 3-METHYL-4-CHLOROPHENOL

Allergies/immunotoxicity

Concern Reference
Human skin toxicant or allergen - strong evidenceCosmetic Ingredient Review Assessments
Human skin toxicant or allergen - strong evidence
Limited evidence of immune system toxicity or allergies (only for products for use on skin)European Union - Classification & Labelling
Limited evidence of immune system toxicity or allergiesNordic Council of Ministers (Nordic Allergy Project)

Endocrine disruption

Concern Reference
Human endocrine disruptor - moderate evidenceEuropean Commission on Endocrine Disruption

Organ system toxicity (non-reproductive)

Concern Reference
Limited evidence of eye toxicity (only for products for use around the eyes)European Union - Classification & Labelling
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List
Classified as toxic or harmful (only for products for use around the mouth; products for use on the lips; products for use on skin)European Union - Classification & Labelling

Occupational hazards

Concern Reference
Allowed workplace exposures restricted to low dosesEuropean Union - Classification & Labelling

Irritation (skin, eyes, or lungs)

Concern Reference
Classified as irritantEuropean Union - Classification & Labelling

Use restrictions

Concern Reference
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualificationsCosmetic Ingredient Review Assessments

Ecotoxicology

Concern Reference
Wildlife and environmental toxicityEuropean Union - Classification & Labelling
Wildlife and environmental toxicityEPA Clean Water Act - Priority Pollutants
Suspected to be an environmental toxin and be persistent or bioaccumulativeEnvironment Canada Domestic Substance List
Suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

Concern Reference
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data gaps

Concern Reference
369 studies in PubMed science library may include information on the toxicity of this chemical see search results ->NLM PubMed

Data Sources

CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
EU (European Union)- Strategy for Endocrine Disrupters 2007. Commision on endocrin disruption requested by the European Parliament in 1998.
European Commission. 2013. Cosing, the European Commission database with information on cosmetic substances and ingredients. Accessed on March 1, 2013 at http://ec.europa.eu/consumers/cosmetics/cosing/ .
NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
Nordic Council of Ministers (Nordic Allergy Project). Kriteriedokumenter fra nordisk allergiprojekt - vurdering af 50 kemiske stoffers evne til at forarsage allergi, en litteraturgennemgang. Nord 1991:51. Copenhagen, 1991.

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EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

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