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METHYL ACETATE


image source: PubChem
Health Concerns of the Ingredient:
Overall Hazard
 
 
Cancer
 
 
Developmental &
reproductive toxicity
 
 
Allergies & immunotoxicity
 
 
Use restrictions
 
 
Other HIGH concerns: Irritation (skin, eyes, or lungs), Occupational hazards, Persistence and bioaccumulation; Other MODERATE concerns: Organ system toxicity (non-reproductive); Other LOW concerns: Data gaps

About METHYL ACETATE: Methyl Acetate is an ester of methyl alcohol and acetic acid.

Function(s): Fragrance Ingredient; Solvent; PERFUMING

Synoym(s): ACETIC ACID, METHYL ESTER; METHYL ESTER ACETIC ACID; METHYL ETHANOATE; ACETATE DE METHYLE (FRENCH) ; DEVOTON; ETHYL ESTER OF MONOACETIC ACID; METHYL ACETATE (ACGIH:OSHA) ; METHYL ETHANOATE; METHYLACETAAT (DUTCH) ; METHYLACETAT (GERMAN) ; METHYLE (ACETATE DE) (FRENCH)

Persistence and bioaccumulation

Concern Reference
Persistent or bioaccumulative and moderate to high toxicity concern in humansEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Organ system toxicity (non-reproductive)

Concern Reference
Classified as medium human health priorityEnvironment Canada Domestic Substance List
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Occupational hazards

Concern Reference
Allowed workplace exposures restricted to moderate doses (only for products that may be aerosolized (airborne))European Union - Classification & Labelling

Irritation (skin, eyes, or lungs)

Concern Reference
Classified as irritantEuropean Union - Classification & Labelling

Data gaps

Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
212 studies in PubMed science library may include information on the toxicity of this chemical see search results ->NLM PubMed

Multiple, additive exposure sources

Concern Reference
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Neurotoxicity

Concern Reference
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox studyNational Library of Medicine HazMap

Miscellaneous

Concern Reference
Occupational hazards related to handlingEuropean Union - Classification & Labelling

Ecotoxicology

Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Data Sources

CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
IFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25
NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

About the ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer