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CI 77499
Score
Data: Fair
CAS1309-37-1
eye shadow (411 products)
lip gloss (240 products)
lipstick (220 products)
mascara (179 products)
eye liner (175 products)
Show all 1,810 products that contain CI 77499.
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CI 77499


image source: PubChem
Health concerns of ingredient
About the ratings
Canceryes
Developmental & reproductive toxicity no information
Allergies & immunotoxicity no information
Use restrictions no information
Contamination concerns: none
Other HIGH concerns: Persistence and bioaccumulation
Other MODERATE concerns: Organ system toxicity (non-reproductive)
Other LOW concerns: Data gaps

About the ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

Function/use(s): Colorant; COSMETIC COLORANT

About CI 77499: CI 77499 is an inorganic colorant primarily composed of iron oxides (ferrous-ferric oxide).

Synonym(s): BLACK IRON OXIDE; FERROSOFERRIC OXIDE; FERROUS-FERRIC OXIDE; MAGNETITE; PIGMENT BLACK 11

Persistence and bioaccumulation

type of concern product conditions reference
Persistent, bioaccumulative in wildlife and humans    National Library of Medicine HazMap
Persistent, bioaccumulative in wildlife    National Library of Medicine HazMap
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Organ system toxicity (non-reproductive)

type of concern product conditions reference
Limited evidence of respiratory toxicity    Klaassen, C
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Cancer

type of concern product conditions reference
Cancer - not classifiable/not likely to be human carcinogen    Int'l Agency for Research on Cancer (IARC) - Carcinogens

Data gaps

type of concern product conditions reference
Not assessed for safety in cosmetics by industry panel  
5,788 studies in PubMed science library may include information on the toxicity of this chemical see search results ->   PubMed

Multiple, additive exposure sources

type of concern product conditions reference
Designated as safe for general or specific, limited use in food   FDA Everything Added to Food

Ecotoxicology

type of concern product conditions reference
Not suspected to be an environmental toxin    Environment Canada Domestic Substance List

Government, industry, academic studies and classifications
government/industry list/academic study appears on list as classification(s)
FDA Everything Added to FoodFERRIC OXIDE• ASP
Environment Canada Domestic Substance ListIRON OXIDE (FE2O3),,Low-Health Priority,Y-Persistent,,,,,,
National Library of Medicine HazMapIRON OXIDESD: No;PE: 10 mg/m3, fume;BA: Yes;TL: 5 mg/m3, as Fe, dust and fume;ID: 2500 mg/m3, as Fe;MA: 1.5 mg/m3, respirable fraction;
Int'l Agency for Research on Cancer (IARC) - CarcinogensFERRIC OXIDEIARC GROUP 3
Klaassen, CIRON OXIDE FUMERespiratory Toxicity Hazards: suspected

Other RTECS® classifications [shown for informational purposes only]
government/industry list/academic study appears on list as classification(s)
RTECS®- TLV/BEI,2005CI 77499• occupationally related - ACGIH TLV (human TWA)
RTECS®- TLV/BEI,2006CI 77499• occupationally related - ACGIH TLV (human TWA)
RTECS®- TLV/BEI,2007CI 77499• occupationally related - ACGIH TLV (human TWA)
RTECS®- "Vrednie chemichescie veshestva 1989CI 77499• biochemical - Multiple enzyme effects (rat TDLo)
• respiratory - Other changes (rat TDLo)
RTECS®- Progress in Biochemical Pharmacology 1978CI 77499• cancer - Tumors at site of application (rat TDLo)
RTECS®- Toxicology Letters 2003CI 77499• respiratory - Other changes (rat TDLo)
• biochemical - Other enzymes (rat TDLo)

references
government/industry list/academic study reference
FDA Everything Added to FoodFDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
Environment Canada Domestic Substance ListEC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
National Library of Medicine HazMapNLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
Int'l Agency for Research on Cancer (IARC) - CarcinogensIARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures).
Scorecard.org Toxicity InformationKlaassen, C., M. Amdur and J. Doull (eds.). Casarett and Doull
RTECS®- TLV/BEI,2005 [shown for informational purposes only]RTECS®- TLV/BEI,2005
RTECS®- TLV/BEI,2006 [shown for informational purposes only]RTECS®- TLV/BEI,2006
RTECS®- TLV/BEI,2007 [shown for informational purposes only]RTECS®- TLV/BEI,2007
RTECS®- "Vrednie chemichescie veshestva 1989 [shown for informational purposes only]RTECS®- "Vrednie chemichescie veshestva. Neorganicheskie soedinenia elementov V-VII groopp" (Hazardous substances. Inornanic substances containing V-VII group elements), Bandman A.L. et al., Chimia, 1989. -,431,1989
RTECS®- Progress in Biochemical Pharmacology 1978 [shown for informational purposes only]RTECS®- Progress in Biochemical Pharmacology. (S. Karger AG, Postfach CH-4009 Basel, Switzerland) V.1- 1965- 14,47,1978
RTECS®- Toxicology Letters 2003 [shown for informational purposes only]RTECS®- Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- 143,223,2003

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