Health Concerns of the Ingredient:
Overall Hazard
Developmental &
reproductive toxicity
Allergies & immunotoxicity
About CI 26100: CI 26100 is classed chemically as a disazo color.
Function(s): Colorant
Synonym(s): RED 225; RED NO. 225
Use restrictions
Concern |
Reference |
Violation of government restrictions - Banned or found unsafe for use in cosmetics | CosIng |
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | Canada - Prohibited and Restricted Cosmetics Ingredients |
Organ system toxicity (non-reproductive)
Concern |
Reference |
Classified as expected to be toxic or harmful | Environment Canada Domestic Substance List |
Persistence and bioaccumulation
Concern |
Reference |
Persistent, bioaccumulative in wildlife | Canada PBTs - Accelerated Reduction/Elimination of Toxics (ARET) |
Ecotoxicology
Concern |
Reference |
Suspected to be an environmental toxin and be persistent or bioaccumulative | Environment Canada Domestic Substance List |
Suspected to be an environmental toxin | Environment Canada Domestic Substance List |
Cancer
Concern |
Reference |
Limited or incomplete evidence of cancer according to safety/hazard data – government assessment cannot classify as human carcinogen due to data gaps | Int'l Agency for Research on Cancer (IARC) - Carcinogens |
Data gaps
Concern |
Reference |
100 studies in PubMed science library may include information on the toxicity of this chemical see search results -> | NLM PubMed |
Data Sources
EC (Environment Canada). 1994. Accelerated Reduction/Elimination of Toxics (ARET). ARET substance list of persistent, bioaccumulative and toxic chemicals. |
EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry. |
European Commission. 2013. Cosing, the European Commission database with information on cosmetic substances and ingredients. Accessed on March 1, 2013 at http://ec.europa.eu/consumers/cosmetics/cosing/ . |
Health Canada. 2007. List of Prohibited and Restricted Cosmetic Ingredients. Canada's Cosmetic Ingredient Hotlist. March 2007. |
IARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures). |
IFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25 |
NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov. |
Products Containing the Ingredient
About the Skin Deep® ratings
EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any.
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