Health Concerns of the Ingredient:
Overall Hazard
Developmental &
reproductive toxicity
Allergies & immunotoxicity
Other LOW concerns: Organ system toxicity (non-reproductive)
About AO1: Ao1 is classed chemically as a triphenylmethane color.
Function(s): Colorant
Synoym(s): FOOD BLUE 2; JAPAN BLUE 1
Use restrictions
| Concern |
Reference |
| Violation of government restrictions - Banned or found unsafe for use in cosmetics | CTFA International Cosmetic Ingredient Dictionary and Handbook |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - | CosIng |
Organ system toxicity (non-reproductive)
| Concern |
Reference |
| One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient) | EPA Toxic Release Inventory PBTs |
| Classified as not expected to be potentially toxic or harmful | Environment Canada Domestic Substance List |
Data gaps
| Concern |
Reference |
| 155 studies in PubMed science library may include information on the toxicity of this chemical see search results -> | NLM PubMed |
Ecotoxicology
| Concern |
Reference |
| Not suspected to be an environmental toxin | Environment Canada Domestic Substance List |
Persistence and bioaccumulation
| Concern |
Reference |
| Not suspected to be bioaccumulative | Environment Canada Domestic Substance List |
Data Sources
| CTFA (Cosmetic, Toiletry and Fragrance Association). 2006. International Cosmetic Ingredient Dictionary and Handbook, 11th Edition. Color Additive Information. Washington, DC. |
| EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry. |
| EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule. |
| European Commission. 2013. Cosing, the European Commission database with information on cosmetic substances and ingredients. Accessed on March 1, 2013 at http://ec.europa.eu/consumers/cosmetics/cosing/ . |
| NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov. |
Products Containing the Ingredient
About the ratings
EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any.
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