Health Concerns of the Ingredient:
Overall Hazard
Developmental &
reproductive toxicity
Allergies & immunotoxicity
About ZINC PYRITHIONE: Ingredients in Volume 1, Introduction, Part A.
Function(s): Antidandruff Agent; Cosmetic Biocide; Hair Conditioning Agent; Preservative; ANTISEBORRHOEIC
Synoym(s): (T-4) -BIS (1-HYDROXY-2 (1H0-PYRIDINETHIONATO-O,S) ZINC; BIS (1-HYDROXY-2 (1H) -PYRIDINETHIONATO) - ZINC; BIS (1-HYDROXY-2 (1H) -PYRIDINETHIONATO) ZINC; PYRITHIONE ZINC; ZINC BIS (2-PYRIDYLTHIO) -N-OXIDE; ZINC PYRITHIONE SUSPENSION; ZINC, BIS (1-HYDROXY-2 (1H) -PYRIDINETHIONATO) -; ZINC, BIS (1HYDROXY2 (1H) PYRIDINETHIONATOO,S) , (T4) ; ZINC, BIS [1- (HYDROXY-.KAPPA.O) -2 (1H) -PYRIDINETHIONATO-.KAPPA.S2] -, (T-4) -; 1-HYDROXY-2-PYRIDINETHIONE, ZINC SALT; 2 (1H) -PYRIDINETHIONE, 1-HYDROXY-, ZINC COMPLEX
Use restrictions
| Concern |
Reference |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - | CosIng |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit) | Japan's Standards for Cosmetics |
Persistence and bioaccumulation
| Concern |
Reference |
| Persistent or bioaccumulative and moderate to high toxicity concern in humans | Environment Canada Domestic Substance List |
| Persistent, bioaccumulative in wildlife | Canada PBTs - Accelerated Reduction/Elimination of Toxics (ARET) |
| Not suspected to be bioaccumulative | Environment Canada Domestic Substance List |
Organ system toxicity (non-reproductive)
| Concern |
Reference |
| Classified as expected to be toxic or harmful | Environment Canada Domestic Substance List |
| Limited evidence of respiratory toxicity (only for products that may be aerosolized (airborne)) | California EPA, Office of Environmental Health Hazard Assessment |
| Limited evidence of toxicity | California EPA, Office of Environmental Health Hazard Assessment |
| One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient) | EPA Toxic Release Inventory PBTs |
| Classified as a low human health priority | Environment Canada Domestic Substance List |
Ecotoxicology
| Concern |
Reference |
| Suspected to be an environmental toxin and be persistent or bioaccumulative | Environment Canada Domestic Substance List |
| Suspected to be an environmental toxin | Environment Canada Domestic Substance List |
Data gaps
| Concern |
Reference |
| 224 studies in PubMed science library may include information on the toxicity of this chemical see search results -> | NLM PubMed |
Data Sources
| California EPA, Office of Environmental Health Hazard Assessment. Air Toxics Hot Spots Program Risk Assessment Guidelines, Part III: Technical Support Document |
| California EPA, Office of Environmental Health Hazard Assessment. Air Toxics Hot Spots Program Risk Assessment Guidelines, Part III: Technical Support Document |
| EC (Environment Canada). 1994. Accelerated Reduction/Elimination of Toxics (ARET). ARET substance list of persistent, bioaccumulative and toxic chemicals. |
| EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry. |
| EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule. |
| European Commission. 2013. Cosing, the European Commission database with information on cosmetic substances and ingredients. Accessed on March 1, 2013 at http://ec.europa.eu/consumers/cosmetics/cosing/ . |
| Japan Ministry of Health, Labour and Welfare. 2006. Standards for Cosmetics. Evaluation and Licensing Division. Pharmaceutical and Food Safety Bureau. |
| NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov. |
Products Containing the Ingredient
About the ratings
EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any.
Learn more |
Legal Disclaimer