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ZINC PYRITHIONE


image source: PubChem
Health Concerns of the Ingredient:
Overall Hazard
 
 
Cancer
 
 
Developmental &
reproductive toxicity
 
 
Allergies & immunotoxicity
 
 
Other HIGH concerns: Persistence and bioaccumulation; Other MODERATE concerns: Organ system toxicity (non-reproductive); Other LOW concerns: Ecotoxicology

About ZINC PYRITHIONE: Ingredients in Volume 1, Introduction, Part A.

Function(s): Antidandruff Agent; Cosmetic Biocide; Hair Conditioning Agent; Preservative; ANTISEBORRHOEIC

Synoym(s): (T-4) -BIS (1-HYDROXY-2 (1H0-PYRIDINETHIONATO-O,S) ZINC; BIS (1-HYDROXY-2 (1H) -PYRIDINETHIONATO) - ZINC; BIS (1-HYDROXY-2 (1H) -PYRIDINETHIONATO) ZINC; PYRITHIONE ZINC; ZINC BIS (2-PYRIDYLTHIO) -N-OXIDE; ZINC PYRITHIONE SUSPENSION; ZINC, BIS (1-HYDROXY-2 (1H) -PYRIDINETHIONATO) -; ZINC, BIS (1HYDROXY2 (1H) PYRIDINETHIONATOO,S) , (T4) ; ZINC, BIS [1- (HYDROXY-.KAPPA.O) -2 (1H) -PYRIDINETHIONATO-.KAPPA.S2] -, (T-4) -; 1-HYDROXY-2-PYRIDINETHIONE, ZINC SALT; 2 (1H) -PYRIDINETHIONE, 1-HYDROXY-, ZINC COMPLEX

Use restrictions

Concern Reference
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - CosIng
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)Japan's Standards for Cosmetics

Persistence and bioaccumulation

Concern Reference
Persistent or bioaccumulative and moderate to high toxicity concern in humansEnvironment Canada Domestic Substance List
Persistent, bioaccumulative in wildlifeCanada PBTs - Accelerated Reduction/Elimination of Toxics (ARET)
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Organ system toxicity (non-reproductive)

Concern Reference
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List
Limited evidence of respiratory toxicity (only for products that may be aerosolized (airborne))California EPA, Office of Environmental Health Hazard Assessment
Limited evidence of toxicityCalifornia EPA, Office of Environmental Health Hazard Assessment
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)EPA Toxic Release Inventory PBTs
Classified as a low human health priorityEnvironment Canada Domestic Substance List

Ecotoxicology

Concern Reference
Suspected to be an environmental toxin and be persistent or bioaccumulativeEnvironment Canada Domestic Substance List
Suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Data gaps

Concern Reference
224 studies in PubMed science library may include information on the toxicity of this chemical see search results ->NLM PubMed

Data Sources

California EPA, Office of Environmental Health Hazard Assessment. Air Toxics Hot Spots Program Risk Assessment Guidelines, Part III: Technical Support Document
California EPA, Office of Environmental Health Hazard Assessment. Air Toxics Hot Spots Program Risk Assessment Guidelines, Part III: Technical Support Document
EC (Environment Canada). 1994. Accelerated Reduction/Elimination of Toxics (ARET). ARET substance list of persistent, bioaccumulative and toxic chemicals.
EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
European Commission. 2013. Cosing, the European Commission database with information on cosmetic substances and ingredients. Accessed on March 1, 2013 at http://ec.europa.eu/consumers/cosmetics/cosing/ .
Japan Ministry of Health, Labour and Welfare. 2006. Standards for Cosmetics. Evaluation and Licensing Division. Pharmaceutical and Food Safety Bureau.
NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

About the ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer