VITAMIN B3
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About the ratings
EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any.
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Function/use(s): Hair Conditioning Agent; ANTISTATIC; SKIN CONDITIONING
About VITAMIN B3: Pantothenic Acid is an organic acid.
Synonym(s): PANTOTHENIC ACID, VITAMIN B5; D-PANTOTHENIC ACID; (+) -PANTOTHENIC ACID; (D) - (+) -PANTOTHENIC ACID; CHICK ANTIDERMATITIS FACTOR; D-PANTOTHENIC ACID; KYSELINA PANTOTHENOVA (CZECH) ; VITAMIN B5
Data gaps |
| type of concern |
product conditions |
reference |
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| Not assessed for safety in cosmetics by industry panel |
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| 2,967 studies in PubMed science library may include information on the toxicity of this chemical
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PubMed |
Ecotoxicology |
| type of concern |
product conditions |
reference |
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| Not suspected to be an environmental toxin |
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Environment Canada Domestic Substance List |
Organ system toxicity (non-reproductive) |
| type of concern |
product conditions |
reference |
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| Classified as not expected to be potentially toxic or harmful |
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Environment Canada Domestic Substance List |
Persistence and bioaccumulation |
| type of concern |
product conditions |
reference |
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| Not suspected to be bioaccumulative |
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Environment Canada Domestic Substance List |
| show more |
| Not suspected to be persistent |
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Environment Canada Domestic Substance List | |
Government, industry, academic studies and classifications |
| government/industry list/academic study |
appears on list as |
classification(s) |
| Environment Canada Domestic Substance List | ß-ALANINE, N-[(2R)-2,4-DIHYDROXY-3,3-DIMETHYL-1-OXOBUTYL]- | ,,,,,,,,, |
Other RTECS® classifications [shown for informational purposes only] |
| government/industry list/academic study |
appears on list as |
classification(s) |
| RTECS®- Bitamin 1962 | VITAMIN B3 | • broad systemic - Broad systemic toxicity (mouse LD50)
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| RTECS®- Journal of the American College of Toxicology 1987 | VITAMIN B3 | • broad systemic - Broad systemic toxicity (mouse LD50)
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| RTECS®- Pharmaceutical Chemistry Journal (English Translation) 1983 | VITAMIN B3 | • brain, nervous system, or behavioral effect - Altered sleep time (including change in righting reflex) (mouse LD50)
• brain, nervous system, or behavioral effect - Somnolence (general depressed activity) (mouse LD50)
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references |
| government/industry list/academic study
| reference
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| Environment Canada Domestic Substance List | EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry. |
| RTECS®- Bitamin 1962 [shown for informational purposes only] | RTECS®- Bitamin. (Nippon Bitamin Gakkai, 4 Ushinomiya-cho, Yoshida, Sakyo-Ku, Kyoto 606, Japan) V.1- -1948 25,297,1962 |
| RTECS®- Journal of the American College of Toxicology 1987 [shown for informational purposes only] | RTECS®- Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. 6(1),139,1987 |
| RTECS®- Pharmaceutical Chemistry Journal (English Translation) 1983 [shown for informational purposes only] | RTECS®- Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- 17,32,1983 |
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