Health Concerns of the Ingredient:
Overall Hazard
Developmental &
reproductive toxicity
Allergies & immunotoxicity
Function(s): Plasticizer; PLASTICISER
Synoym(s): 1-ISOPROPYL-2,2-DIMETHYL-TRIMETHYLENE DIISOBUTYRATE; 1-ISOPROPYL-2,2-DIMETHYLTRIMETHYLENE DIISOBUTYRATE; 2,2,4-TRIMETHYL-1,3-PENTANEDIOL DIISOBUTYRATE; 2,2-DIMETHYL-1- (1-METHYLETHYL) -1,3-PROPANEDIYL ESTER PROPANOIC ACID, 2-METHYL-; 2-METHYL- 2,2-DIMETHYL-1- (1-METHYLETHYL) -1,3-PROPANEDIYL ESTER PROPANOIC ACID; PROPANOIC ACID, 2-METHYL-, 2,2-DIMETHYL-1- (1-METHYLETHYL) -1,3-PROPANEDIYL ESTER; PROPANOIC ACID, 2METHYL, 2,2DIMETHYL1 (1METHYLETHYL) 1,3PROPANEDIYL ESTER; 2,2,4-TRIMETHYL-1,3-PENTANEDIOL DIISOBUTYRATE; 2,2,4-TRIMETHYLPENTANEDIOL-1,3-DIISOBUTYRATE; ISOBUTYRIC ACID, 1-ISOPROPYL-2,2-DIMETHYLTRIMETHYLENE ESTER; KODAFLEX TXIB
Persistence and bioaccumulation
| Concern |
Reference |
|---|
| Persistent or bioaccumulative and moderate to high toxicity concern in humans | Environment Canada Domestic Substance List |
| Not suspected to be persistent | Environment Canada Domestic Substance List |
Organ system toxicity (non-reproductive)
| Concern |
Reference |
|---|
| Classified as expected to be toxic or harmful | Environment Canada Domestic Substance List |
| Classified as a low human health priority | Environment Canada Domestic Substance List |
Ecotoxicology
| Concern |
Reference |
|---|
| Suspected to be an environmental toxin and be persistent or bioaccumulative | Environment Canada Domestic Substance List |
| Suspected to be an environmental toxin | Environment Canada Domestic Substance List |
Data gaps
| Concern |
Reference |
|---|
| 18 studies in PubMed science library may include information on the toxicity of this chemical see search results -> | NLM PubMed |
Data Sources
| EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry. |
| IFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25 |
| NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov. |
Products Containing the Ingredient
About the ratings
EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any.
Learn more |
Legal Disclaimer
