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Data available:
 
Fair

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TETRASODIUM EDTA


image source: PubChem
Health Concerns of the Ingredient:
Overall Hazard
 
 
Cancer
 
 
Developmental &
reproductive toxicity
 
 
Allergies & immunotoxicity
 
 
Use restrictions
 
 
Other HIGH concerns: Occupational hazards; Other MODERATE concerns: Organ system toxicity (non-reproductive); Other LOW concerns: Enhanced skin absorption, Data gaps

About TETRASODIUM EDTA: EDTA (ethylenediaminetetraacetic acid) is a chelating agent, used to sequester and decrease the reactivity of metal ions that may be present in a product.

Function(s): Chelating Agent

Synoym(s): EDETATE SODIUM; ETHYLENEDIAMINETETRAACETIC ACID TETRASODIUM SALT; GLYCINE, N,N 1,2ETHANEDIYLBIS [N (CARBOXYMETHYL) , TETRASODIUM SALT; GLYCINE, N,N'-1,2-ETHANEDIYLBIS [N- (CARBOXYMETHYL) -, TETRASODIUM SALT; N,N'-1,2-ETHANEDIYL BIS [N- (CARBOXYMETHYL) GLYCINE, TETRASODIUM SALT; N,N'-1,2-ETHANEDIYLBIS [N- (CARBOXYMETHYL) - TETRASODIUM SALT GLYCINE; N,N'-1,2-ETHANEDIYLBIS [N- (CARBOXYMETHYL) GLYCINE] , TETRASODIUM SALT; SODIUM EDETATE; TETRASODIUM EDE TATE TETRAHYDRATE; TETRASODIUM EDETATE; TETRASODIUM EDETATE DIHYDRATE

Occupational hazards

Concern Reference
Allowed workplace exposures restricted to low dosesEuropean Union - Classification & Labelling

Organ system toxicity (non-reproductive)

Concern Reference
Limited evidence of eye toxicity (only for products for use around the eyes)European Union - Classification & Labelling
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List

Enhanced skin absorption

Concern Reference
Penetration enhancerCosmetic Ingredient Review Assessments

Multiple, additive exposure sources

Concern Reference
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Data gaps

Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
2,947 studies in PubMed science library may include information on the toxicity of this chemical see search results ->NLM PubMed

Data Sources

CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
IFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25
NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

About the ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer