Health Concerns of the Ingredient:
Overall Hazard
Developmental &
reproductive toxicity
Allergies & immunotoxicity
Function(s): Antioxidant
Synoym(s): 2,2-BIS [ [3 ,5-BIS (1,1-DIMETHYLETHYL) -4-HYDROXYPHENYL] -1-OXOPROPOXY] METHYL] 1,3-PROPANEDIYL ESTER; 2,2-BIS [ [3- [3,5-BIS (1,1-DIMETHYLETHYL) -4-HYDROXYPHENYL] -1-OXOPROPOXY] METHYL] -1,3-PROPANEDIYL ESTER; 3,5-BIS (1,1-DIMETHYLETHYL) -4-HYDROXY-, BENZENEPROPANOIC ACID; 3,5-BIS (1,1-DIMETHYLETHYL) -4-HYDROXYBENZENEPROPANOIC ACID,; BENZENEPROPANOIC ACID 3,5-BIS (1,1-DIMETHYLETHYL) -4-HYDROXY-; BENZENEPROPANOIC ACID, 3,5-BIS (1,1-DIMETHYLETHYL) -4-HYDROXY-,; BENZENEPROPANOIC ACID, 3,5BIS (1,1DIMETHYLETHYL) 4HYDROXY, 2,2BIS [ [3 [3,5BIS (1,1DIMETHYLETHYL) 4HYDROXYPHENYL] 1OXOPROPOXY] METHYL] 1,3PROPANEDIYL ESTER; PENTAERYTHRITOL TETRAKIS (3- (3,5-DI-TERT-BUTYL-4-HYDROXYPHENYL) PROPIONATE) ; TETRABUTYL PENTAERYTHRITYL HYDROXYHYDROCINNAMATE; TETRABUTYL PENTARYTHRITYL HYDRYOXYHYDROCINNAMATE; TETRADIBUTYL PENTAERITYL HYDROXYHYDOCINNAMATE
Persistence and bioaccumulation
| Concern |
Reference |
|---|
| Persistent, bioaccumulative in wildlife | EU PTBs - PRIO database & Secondary PRIO database |
| Not suspected to be bioaccumulative | Environment Canada Domestic Substance List |
Ecotoxicology
| Concern |
Reference |
|---|
| Suspected to be an environmental toxin and be persistent or bioaccumulative (uncertainty in environmental toxicity or persistence/bioaccumulation) | Environment Canada Domestic Substance List |
| Uncertain environmental toxin and uncertain persistent or bioaccumulative | Environment Canada Domestic Substance List |
Organ system toxicity (non-reproductive)
| Concern |
Reference |
|---|
| Classified as not expected to be potentially toxic or harmful | Environment Canada Domestic Substance List |
| Classified as a low human health priority | Environment Canada Domestic Substance List |
Data gaps
| Concern |
Reference |
|---|
| 67 studies in PubMed science library may include information on the toxicity of this chemical see search results -> | NLM PubMed |
Data Sources
| EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry. |
| EU (European Union). 2006. Persistent, bioaccumulative chemicals identified in PRIO database - a tool for risk reduction of chemicals. Secondary PRIO database - a tool for risk reduction of chemicals. Secondary Kemi. Place Published, Kemi-Swedish Chemicals Inspectorate. |
| IFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25 |
| NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov. |
Products Containing the Ingredient
About the ratings
EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any.
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