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TARTRAZINE
Score
Data: Fair
CAS1934-21-0
shampoo (4 products)
fragrance for women (2 products)
facial cleanser (2 products)
conditioner (2 products)
antiperspirant/ deodorant (men's) (2 products)
Show all 24 products that contain TARTRAZINE.
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TARTRAZINE


image source: PubChem
Health concerns of ingredient
About the ratings
Cancer no information
Developmental & reproductive toxicity no information
Allergies & immunotoxicity no information
Use restrictionsyes
Contamination concerns: none
Other MODERATE concerns: Persistence and bioaccumulation, Organ system toxicity (non-reproductive)
Other LOW concerns: Data gaps

About the ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

Function/use(s): Colorant

About TARTRAZINE: Acid Yellow 23 is classed chemically as a pyrazole color.

Synonym(s): ACID YELLOW 23,

Use restrictions

type of concern product conditions reference
Violation of government restrictions - Banned or found unsafe for use in cosmetics   CTFA International Cosmetic Ingredient Dictionary and Handbook

Persistence and bioaccumulation

type of concern product conditions reference
Persistent or bioaccumulative and moderate to high toxicity concern in humans    Environment Canada Domestic Substance List
show more

Organ system toxicity (non-reproductive)

type of concern product conditions reference
Classified as medium human health priority    Environment Canada Domestic Substance List
show more

Data gaps

type of concern product conditions reference
Not assessed for safety in cosmetics by industry panel  
443 studies in PubMed science library may include information on the toxicity of this chemical see search results ->   PubMed

Multiple, additive exposure sources

type of concern product conditions reference
Designated as safe for general or specific, limited use in food   FDA Everything Added to Food

Ecotoxicology

type of concern product conditions reference
Not suspected to be an environmental toxin    Environment Canada Domestic Substance List

Government, industry, academic studies and classifications
government/industry list/academic study appears on list as classification(s)
FDA Everything Added to FoodFD&C YELLOW NO. 5• ASP
Environment Canada Domestic Substance List1H-PYRAZOLE-3-CARBOXYLIC ACID, 4,5-DIHYDRO-5-OXO-1-(4-SULFOPHENYL) -4-[(4-SULFOPHENYL)AZO]-, TRISODIUM SALT,,Post2006-Health Priority,Y-Persistent,,,,,,
CTFA International Cosmetic Ingredient Dictionary and HandbookACID YELLOW 23Color Additives - Miscellaneous (not approved)
IFRA Fragrance Ingredient List1H-PYRAZOLE-3-CARBOXYLIC ACID, 4,5-DIHYDRO-5-OXO-1-(4-SULFOPHENYL)-4-[(4-SULFOPHENYL)AZO]-, TRISODIUM SALTreported as used in fragrance compounds in 2008

Other RTECS® classifications [shown for informational purposes only]
government/industry list/academic study appears on list as classification(s)
RTECS®- Annals of Allergy 1959TARTRAZINE• musculoskeletal - Changes in teeth and supporting structures ( human TDLo)
• brain, nervous system, or behavioral effect - Paresthesis ( human TDLo)
RTECS®- Archives of Toxicology 1987TARTRAZINE• mutagenic - Positive mutation assay: body fluid assay (rat )
RTECS®- Archives of Toxicology 1987TARTRAZINE• mutagenic - Positive mutation assay: body fluid assay (rat )
RTECS®- FAO Nutrition Meetings Report Series 1966TARTRAZINE• broad systemic - Broad systemic toxicity (mouse LD50)
RTECS®- Food and Chemical Toxicology 1982TARTRAZINE• mutagenic - Positive mutation assay: Cytogenetic Analysis (mammal fbr)
RTECS®- Food and Chemical Toxicology 1984TARTRAZINE• mutagenic - Positive mutation assay: Cytogenetic Analysis (hamster fbr)
RTECS®- Food and Chemical Toxicology 2004TARTRAZINE• mutagenic - Positive mutation assay: Mutation in Micro-organism (Salmonella typhimurium )
RTECS®- Food and Chemical Toxicology 1982TARTRAZINE• mutagenic - Positive mutation assay: Cytogenetic Analysis (mammal fbr)
RTECS®- Food and Chemical Toxicology 1984TARTRAZINE• mutagenic - Positive mutation assay: Cytogenetic Analysis (hamster fbr)
RTECS®- Food and Chemical Toxicology 2004TARTRAZINE• mutagenic - Positive mutation assay: Mutation in Micro-organism (Salmonella typhimurium )
RTECS®- Food and Chemical Toxicology 2006TARTRAZINE• reproductive - Behavioral (mouse TDLo)
RTECS®- Gann Monograph on Cancer Research 1981TARTRAZINE• mutagenic - Positive mutation assay: Cytogenetic Analysis (hamster lng)
RTECS®- Gann Monograph on Cancer Research 1981TARTRAZINE• mutagenic - Positive mutation assay: Cytogenetic Analysis (hamster lng)
RTECS®- Journal of Pharmacy and Pharmacology 1958TARTRAZINE• brain, nervous system, or behavioral effect - Food intake (animal) (rat TDLo)
RTECS®- Journal of Toxicology and Environmental Health 1977TARTRAZINE• developmental - Behavioral (rat TDLo)
• reproductive - Blood and lymphatic system (rat TDLo)
RTECS®- Mutation Research 1989TARTRAZINE• mutagenic - Positive mutation assay: (Drosophila melanogaster orl)
RTECS®- Mutation Research 2002TARTRAZINE• mutagenic - Positive mutation assay: DNA Damage (mouse orl)
RTECS®- Mutation Research 1989TARTRAZINE• mutagenic - Positive mutation assay: (Drosophila melanogaster orl)
RTECS®- Mutation Research 2002TARTRAZINE• mutagenic - Positive mutation assay: DNA Damage (mouse orl)
RTECS®- Oyo Yakuri 1982TARTRAZINE• reproductive - Growth statistics (rat TDLo)
• reproductive - Weaning or lactation index (rat TDLo)
RTECS®- Soviet Genetics 1975TARTRAZINE• mutagenic - Positive mutation assay: Cytogenetic Analysis ( human lym)
RTECS®- Soviet Genetics 1975TARTRAZINE• mutagenic - Positive mutation assay: Cytogenetic Analysis ( human lym)

references
government/industry list/academic study reference
FDA Everything Added to FoodFDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
Environment Canada Domestic Substance ListEC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
CTFA International Cosmetic Ingredient Dictionary and HandbookCTFA (Cosmetic, Toiletry and Fragrance Association). 2006. International Cosmetic Ingredient Dictionary and Handbook, 11th Edition. Color Additive Information. Washington, DC.
IFRA Fragrance Ingredient ListIFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25
RTECS®- Annals of Allergy 1959 [shown for informational purposes only]RTECS®- Annals of Allergy. (American College of Allergists, POB 20671, Bloomington, MN 55420) V.1- -1943 17,719,1959
RTECS®- Archives of Toxicology 1987 [shown for informational purposes only]RTECS®- Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- 60,328,1987
RTECS®- Archives of Toxicology 1987 [shown for informational purposes only]RTECS®- Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 60,328,1987
RTECS®- FAO Nutrition Meetings Report Series 1966 [shown for informational purposes only]RTECS®- FAO Nutrition Meetings Report Series. (Rome, Italy) No.?-57, 1948-77. Discontinued. 38B,88,1966
RTECS®- Food and Chemical Toxicology 1982 [shown for informational purposes only]RTECS®- Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 20,461,1982
RTECS®- Food and Chemical Toxicology 1984 [shown for informational purposes only]RTECS®- Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 22,623,1984
RTECS®- Food and Chemical Toxicology 2004 [shown for informational purposes only]RTECS®- Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 42,2029,2004
RTECS®- Food and Chemical Toxicology 1982 [shown for informational purposes only]RTECS®- Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- 20,461,1982
RTECS®- Food and Chemical Toxicology 1984 [shown for informational purposes only]RTECS®- Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- 22,623,1984
RTECS®- Food and Chemical Toxicology 2004 [shown for informational purposes only]RTECS®- Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- 42,2029,2004
RTECS®- Food and Chemical Toxicology 2006 [shown for informational purposes only]RTECS®- Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- 44,179,2006
RTECS®- Gann Monograph on Cancer Research 1981 [shown for informational purposes only]RTECS®- Gann Monograph on Cancer Research. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No. 11- 1971- 27,95,1981
RTECS®- Gann Monograph on Cancer Research 1981 [shown for informational purposes only]RTECS®- Gann Monograph on Cancer Research. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No. 11- 27,95,1981
RTECS®- Journal of Pharmacy and Pharmacology 1958 [shown for informational purposes only]RTECS®- Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- 10,625,1958
RTECS®- Journal of Toxicology and Environmental Health 1977 [shown for informational purposes only]RTECS®- Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- 2,1211,1977
RTECS®- Mutation Research 1989 [shown for informational purposes only]RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 224,479,1989
RTECS®- Mutation Research 2002 [shown for informational purposes only]RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 519,103,2002
RTECS®- Mutation Research 1989 [shown for informational purposes only]RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- -1964 224,479,1989
RTECS®- Mutation Research 2002 [shown for informational purposes only]RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- -1964 519,103,2002
RTECS®- Oyo Yakuri 1982 [shown for informational purposes only]RTECS®- Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- -1967 24,399,1982
RTECS®- Soviet Genetics 1975 [shown for informational purposes only]RTECS®- Soviet Genetics. English translation of GNKAA5. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.2- 1966- 11,528,1975
RTECS®- Soviet Genetics 1975 [shown for informational purposes only]RTECS®- Soviet Genetics. English translation of GNKAA5. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.2- 11,528,1975

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