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SODIUM HYDROXYMETHYLGLYCINATE (FORMALDEHYDE RELEASER)


image source: PubChem
Health Concerns of the Ingredient:
Overall Hazard
 
 
 
 
Developmental &
reproductive toxicity
 
 
 

About SODIUM HYDROXYMETHYLGLYCINATE (FORMALDEHYDE RELEASER): Sodium hydroxymethylglycinate is an antimicrobial preservative that works by forming formaldehyde in cosmetic products. People exposed to such formaldehyde-releasing ingredients may develop a formalde ... read more

Function(s): Hair Conditioning Agent; Preservative

Synoym(s): SODIUM HYDROXYMETHYLGLYCINATE, GLYCINE, N- (HYDROXYMETHYL) -, MONOSODIUM SALT; GLYCINE, N- (HYDROXYMETHYL) -, SODIUM SALT; GLYCINE, N- (HYDROXYMETHYL) -. MONOSODIUM SALT; HYDROXYMETHYLAMINOACETIC ACID, SODIUM SALT; N- (HYDROXYMETHYL) - SODIUM SALT GLYCINE; N- (HYDROXYMETHYL) -. MONOSODIUM SALT GLYCINE; N- (HYDROXYMETHYL) GLYCINE, SODIUM SALT; SODIUM HYDROXYMETHYLGLYCINATE SODIUM HYDROXYMETHYLGLYCINATE; SODIUM N- (HYDROXYMETHYL) GLYCINATE; SODIUM SALT GLYCINE, N- (HYDROXYMETHYL) -; SODIUM SALT N- (HYDROXYMETHYL) GLYCINE

Allergies/immunotoxicity

Concern Reference
Known human toxicant or allergen
Human toxicant or allergen - strong evidenceDe Groot AC
Human allergen toxicant or allergen - moderate evidenceRussell K, Jacob SE

Cancer

Concern Reference
Cancer - limited evidenceIARC (International Agency for Research on Cancer)

Use restrictions

Concern Reference
Determined safe for use in cosmetics, subject to concentration or use limitations - Scientific Committee on Cosmetic Products and Non-Food Products (SCCPNP)

Data gaps

Concern Reference
2 studies in PubMed science library may include information on the toxicity of this chemical see search results ->NLM PubMed

Chemical release concerns

Chemical Score
FORMALDEHYDE
Data: Fair

Data Sources

De Groot AC. 2010. Formaldehyde-releasers in cosmetics: relationship to formaldehyde contact allergy. Contact Dermatitis, 62: 2–17.
European Commission. 2013. Cosing, the European Commission database with information on cosmetic substances and ingredients. Accessed on March 1, 2013 at http://ec.europa.eu/consumers/cosmetics/cosing/ .
Formaldehyde - Global Harmonized System (GHS)
IARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99.
NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
Russell K, Jacob SE. 2010. Sodium hydroxymethylglycinate. Dermatitis. Apr;21(2):109-10.
Scientific Committee on Cosmetic Products and Non-Food Products (SCCPNP). 2002. OPINION CONCERNING A CLARIFICATION ON THE FORMALDEHYDE AND PARA-FORMALDEHYDE ENTRY IN DIRECTIVE 76/768/EEC ON COSMETIC PRODUCTS. SCCNFP/587/02.http://ec.europa.eu/food/fs/sc/sccp/out187_en.pdf

About the ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer