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SODIUM HYDROXIDE
Score
Data: Fair
CAS1310-73-2
moisturizer (292 products)
facial moisturizer/ treatment (255 products)
bar soap (227 products)
anti-aging (163 products)
facial cleanser (158 products)
Show all 1,790 products that contain SODIUM HYDROXIDE.
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SODIUM HYDROXIDE


image source: PubChem
Health concerns of ingredient
About the ratings
Cancer no information
Developmental & reproductive toxicity no information
Allergies & immunotoxicity no information
Use restrictions no information
Contamination concerns: none
Other MODERATE concerns: Organ system toxicity (non-reproductive)
Other LOW concerns: Irritation (skin, eyes, or lungs), Data gaps, Occupational hazards

About the ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

Function/use(s): Denaturant; pH Adjuster; BUFFERING

About SODIUM HYDROXIDE: Sodium Hydroxide is a highly caustic and reactive inorganic base.

Synonym(s): CAUSTIC SODA; SODIUM HYDROXIDE SOLUTION; SODIUM HYDRATE; CAUSTIC SODA; SODIUM HYDROXIDE; SODIUM HYDROXIDE; SODIUM HYDROXIDE (NA (OH) ) ; CAUSTIC SODA; HYDROXYDE DE SODIUM (FRENCH) ; LEWIS-RED DEVIL LYE; NATRIUMHYDROXID (GERMAN) ; NATRIUMHYDROXYDE (DUTCH) ; SODA LYE

Organ system toxicity (non-reproductive)

type of concern product conditions reference
Classified as medium human health priority    Environment Canada Domestic Substance List
Classified as expected to be toxic or harmful    Environment Canada Domestic Substance List

Occupational hazards

type of concern product conditions reference
Strong evidence of occupational hazards    CHE Toxicant and Disease Database
show more

Data gaps

type of concern product conditions reference
Not assessed for safety in cosmetics by industry panel  
5,907 studies in PubMed science library may include information on the toxicity of this chemical see search results ->   PubMed

Ecotoxicology

type of concern product conditions reference
Not suspected to be an environmental toxin    Environment Canada Domestic Substance List

Multiple, additive exposure sources

type of concern product conditions reference
Designated as safe for general or specific, limited use in food   FDA Food Additive Status
Designated as safe for general or specific, limited use in food   FDA Everything Added to Food

Miscellaneous

type of concern product conditions reference
Occupational hazards related to handling   European Union - Classification & Labelling

Persistence and bioaccumulation

type of concern product conditions reference
Not suspected to be bioaccumulative    Environment Canada Domestic Substance List

Government, industry, academic studies and classifications
government/industry list/academic study appears on list as classification(s)
European Union - Classification & LabellingSODIUM HYDROXIDEC; R35
FDA Food Additive StatusSODIUM HYDROXIDE• B&N
• GRAS/FS
• Cocoa Prods - Part 163
• MISC
• GRAS - CFR184.1763
• BC
• REG
• GMP
• Boiler water additive - CFR173.310
• In animal feeds - CFR582.1763
• MISC
• REG
• < 1% - In modifying food starch - CFR172.892
• MISC - Used in manufacture of modified hop extract - CFR172.560
• MIS
Association of Occupational and Environmental ClinicsSODIUM HYDROXIDE• o
CHE Toxicant and Disease DatabaseSODIUM HYDROXIDECOPD (chronic obstructive pulmonary disease) - Good
FDA Everything Added to FoodSODIUM HYDROXIDE• ASP
Environment Canada Domestic Substance ListSODIUM HYDROXIDE (NA(OH))Y-Categorization,Y-Human health,Moderate-Health Priority,Y-Persistent,,,,,,
IFRA Fragrance Ingredient ListSODIUM HYDROXIDEreported as used in fragrance compounds in 2008
National Library of Medicine HazMapSODIUM HYDROXIDESD: No;DE: Skin Burns;TP: Yes;PE: 2 mg/m3;CE: 2 mg/m3;FL: 0: will not burn;ID: 10 mg/m3;
EPA Toxic Release Inventory PBTsSODIUM HYDROXIDEToxic under the EPA's Toxics Release Inventory
A Relational Database of Hazardous Chemicals and Occupational Diseases, 2000CAUSTIC SODASkin or Sense Organ Toxicity Hazards: suspected
A Relational Database of Hazardous Chemicals and Occupational Diseases, 2000CAUSTIC SODARespiratory Toxicity Hazards: suspected
RTECS®- Journal of Investigative Dermatology 1988SODIUM HYDROXIDE• skin - Primary skin irritant ( human )
RTECS®- Toxicology and Applied Pharmacology 1964SODIUM HYDROXIDE• sense organ - Primary eye irritant (monkey )

Other RTECS® classifications [shown for informational purposes only]
government/industry list/academic study appears on list as classification(s)
RTECS®- "Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku," Marhold, J 1972SODIUM HYDROXIDE• sense organ - Primary eye irritant (rabbit )
• skin - Primary skin irritant (rabbit )
RTECS®- "Vrednie chemichescie veshestva 1998SODIUM HYDROXIDE• brain, nervous system, or behavioral effect - Anorexia (human) ( human LDLo)
• metabolic - Body temperature increase ( human LDLo)
• skin - Primary irritation ( human LDLo)
RTECS®- American Journal of Ophthalmology 1946SODIUM HYDROXIDE• sense organ - Primary eye irritant (rabbit )
RTECS®- American Journal of Ophthalmology 1946SODIUM HYDROXIDE• sense organ - Primary eye irritant (rabbit )
RTECS®- Comptes Rendus Hebdomadaires des Seances, Academie des Sciences 1963SODIUM HYDROXIDE• broad systemic - Broad systemic toxicity (mouse LD50)
RTECS®- Cytobios 1988SODIUM HYDROXIDE• mutagenic - Positive mutation assay: Cytogenetic Analysis (hamster lng)
RTECS®- Cytobios 1988SODIUM HYDROXIDE• mutagenic - Positive mutation assay: Cytogenetic Analysis (hamster lng)
RTECS®- Journal of Investigative Dermatology 1988SODIUM HYDROXIDE• skin - Primary skin irritant ( human )
RTECS®- Mutation Research 1989SODIUM HYDROXIDE• mutagenic - Positive mutation assay: Cytogenetic Analysis (hamster ovr)
RTECS®- Mutation Research 1989SODIUM HYDROXIDE• mutagenic - Positive mutation assay: Cytogenetic Analysis (hamster ovr)
RTECS®- Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie 1937SODIUM HYDROXIDE• broad systemic - Broad systemic toxicity (rabbit LDLo)
RTECS®- Nucleus (Calcutta) 1966SODIUM HYDROXIDE• mutagenic - Positive mutation assay: Cytogenetic Analysis (grasshopper par)
RTECS®- Nucleus (Calcutta) 1966SODIUM HYDROXIDE• mutagenic - Positive mutation assay: Cytogenetic Analysis (grasshopper par)
RTECS®- Oyo Yakuri 1983SODIUM HYDROXIDE• sense organ - Primary eye irritant (rabbit )
RTECS®- Oyo Yakuri 1983SODIUM HYDROXIDE• sense organ - Primary eye irritant (rabbit )
RTECS®- Toxicology and Applied Pharmacology 1964SODIUM HYDROXIDE• sense organ - Primary eye irritant (rabbit )
RTECS®- Toxicology and Applied Pharmacology 1964SODIUM HYDROXIDE• sense organ - Primary eye irritant (monkey )
RTECS®- Toxicology 1982SODIUM HYDROXIDE• sense organ - Primary eye irritant (rabbit )
RTECS®- Toxicology 1982SODIUM HYDROXIDE• sense organ - Primary eye irritant (rabbit )

references
government/industry list/academic study reference
European Union - Classification & LabellingCPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
FDA Food Additive StatusFDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
Association of Occupational and Environmental ClinicsAOEC (Association of Occupational and Environmental Clinics). 2009. AEOC exposures codes and asthmagen designation.
CHE Toxicant and Disease DatabaseCHE (The Collaborative on Health and the Environment). 2006. Toxicant and Disease Database.
FDA Everything Added to FoodFDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
Environment Canada Domestic Substance ListEC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
IFRA Fragrance Ingredient ListIFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25
National Library of Medicine HazMapNLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
EPA Toxic Release Inventory PBTsEPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
Scorecard.org Toxicity InformationA Relational Database of Hazardous Chemicals and Occupational Diseases. Browse Haz-Map by Adverse Effects http://hazmap.nlm.nih.gov/hazmapadv.html; California EPA, Office of Environmental Health Hazard Assessment. Acute Reference Exposure Levels (RELs), Averaging Times, and Toxicologic Endpoints. Includes all Acute Reference Exposure Levels (ARELs) developed by OEHHA through May 2000http://www.oehha.org/air/acute_rels/allAcRELs.html;California EPA, Office of Environmental Health Hazard Assessment. Air Toxics Hot Spots Program Risk Assessment Guidelines, Part III: Technical Support Document "Determination of Noncancer Chronic Reference Exposure Levels". Includes all Chronic Reference Exposure Levels (CRELs) adopted by OEHHA as of August 2003 (http://www.oehha.ca.gov/air/chronic_rels/AllChrels.html, plus draft CRELS proposed through March 2004 (http://www.oehha.ca.gov/air/chronic_rels/index.html.
Scorecard.org Toxicity InformationA Relational Database of Hazardous Chemicals and Occupational Diseases. Browse Haz-Map by Adverse Effects http://hazmap.nlm.nih.gov/hazmapadv.html; California EPA, Office of Environmental Health Hazard Assessment. Acute Reference Exposure Levels (RELs), Averaging Times, and Toxicologic Endpoints. Includes all Acute Reference Exposure Levels (ARELs) developed by OEHHA through May 2000http://www.oehha.org/air/acute_rels/allAcRELs.html;California EPA, Office of Environmental Health Hazard Assessment. Air Toxics Hot Spots Program Risk Assessment Guidelines, Part III: Technical Support Document "Determination of Noncancer Chronic Reference Exposure Levels". Includes all Chronic Reference Exposure Levels (CRELs) adopted by OEHHA as of August 2003 (http://www.oehha.ca.gov/air/chronic_rels/AllChrels.html, plus draft CRELS proposed through March 2004 (http://www.oehha.ca.gov/air/chronic_rels/index.html.
RTECS®- Journal of Investigative Dermatology 1988RTECS®- Journal of Investigative Dermatology. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1938- 68,192,1988
RTECS®- Toxicology and Applied Pharmacology 1964RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 6,701,1964
RTECS®- "Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku," Marhold, J 1972 [shown for informational purposes only]RTECS®- "Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku," Marhold, J.V., Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha, Czechoslovakia, 1972 -,7,1972
RTECS®- "Vrednie chemichescie veshestva 1998 [shown for informational purposes only]RTECS®- "Vrednie chemichescie veshestva. Neorganicheskie soedinenia elementov I-IV groopp" (Hazardous substances. Inornanic substances containing I-IV group elements), Filov V.A., Chimia, 1988. -,37,1998
RTECS®- American Journal of Ophthalmology 1946 [shown for informational purposes only]RTECS®- American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N. Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 1918- 29,1363,1946
RTECS®- American Journal of Ophthalmology 1946 [shown for informational purposes only]RTECS®- American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N. Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 29,1363,1946
RTECS®- Comptes Rendus Hebdomadaires des Seances, Academie des Sciences 1963 [shown for informational purposes only]RTECS®- Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. (Paris, France) V.1-261, 1835-1965. For publisher information, see CRASEV. 257,791,1963
RTECS®- Cytobios 1988 [shown for informational purposes only]RTECS®- Cytobios. (Faculty Press, 88 Regent St., Cambridge, UK) V.1- 1969- 55,167,1988
RTECS®- Cytobios 1988 [shown for informational purposes only]RTECS®- Cytobios. (Faculty Press, 88 Regent St., Cambridge, UK) V.1- 55,167,1988
RTECS®- Journal of Investigative Dermatology 1988 [shown for informational purposes only]RTECS®- Journal of Investigative Dermatology. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 68,192,1988
RTECS®- Mutation Research 1989 [shown for informational purposes only]RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 225,55,1989
RTECS®- Mutation Research 1989 [shown for informational purposes only]RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- -1964 225,55,1989
RTECS®- Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie 1937 [shown for informational purposes only]RTECS®- Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. 184,587,1937
RTECS®- Nucleus (Calcutta) 1966 [shown for informational purposes only]RTECS®- Nucleus (Calcutta). (Dr. A.K. Sharma, Centre of Advanced Studies in Cell and Chromosome Research, Calcutta, 35 Baliygunge Circular Rd., Calcutta 700 019, India) V.1- 1958- 9,119,1966
RTECS®- Nucleus (Calcutta) 1966 [shown for informational purposes only]RTECS®- Nucleus (Calcutta). (Dr. A.K. Sharma, Centre of Advanced Studies in Cell and Chromosome Research, Calcutta, 35 Baliygunge Circular Rd., Calcutta 700 019, India) V.1- 9,119,1966
RTECS®- Oyo Yakuri 1983 [shown for informational purposes only]RTECS®- Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- 26,627,1983
RTECS®- Oyo Yakuri 1983 [shown for informational purposes only]RTECS®- Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- -1967 26,627,1983
RTECS®- Toxicology and Applied Pharmacology 1964 [shown for informational purposes only]RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 6,701,1964
RTECS®- Toxicology and Applied Pharmacology 1964 [shown for informational purposes only]RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 6,701,1964
RTECS®- Toxicology 1982 [shown for informational purposes only]RTECS®- Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- 23,281,1982
RTECS®- Toxicology 1982 [shown for informational purposes only]RTECS®- Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 23,281,1982

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