| Score | |
| CAS | 144-55-8 |
| bath oil/ salts/ soak (253 products) | |
| toothpaste (146 products) | |
| antiperspirant/ deodorant (81 products) | |
| tooth whitening (53 products) | |
| moisturizer (51 products) | |
| Show all 642 products that contain SODIUM BICARBONATE. | |
| how to read the score | |
image source: PubChem |
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Function/use(s): Abrasive; Buffering Agent; Deodorant Agent; Oral Care Agent; Oral Health Care Drug;pHAdjuster; Skin Protectant; SKIN PROTECTING
About SODIUM BICARBONATE: Sodium bicarbonate (baking soda) is an inorganic salt
Synonym(s): BAKING SODA; BICARBONATE OF SODA; CARBONIC ACID, MONOSODIUM SALT; SODA BICARBONATE; MONOSODIUM SALT CARBONIC ACID; CARBONIC ACID MONOSODIUM SALT; SODIUM HYDROGENCARBONATE; BAKING SODA; BICARBONATE OF SODA; CARBONIC ACID MONOSODIUM SALT; COL-EVAC
Data gaps | ||
|---|---|---|
| type of concern | product conditions | reference |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | Cosmetic Ingredient Review Assessments | |
| 6,723 studies in PubMed science library may include information on the toxicity of this chemical see search results -> | PubMed | |
Ecotoxicology | ||
|---|---|---|
| type of concern | product conditions | reference |
| Not suspected to be an environmental toxin | Environment Canada Domestic Substance List | |
Multiple, additive exposure sources | ||
|---|---|---|
| type of concern | product conditions | reference |
| Designated as safe for general or specific, limited use in food | FDA Everything Added to Food | |
| Designated as safe for general or specific, limited use in food | FDA Food Additive Status | |
Organ system toxicity (non-reproductive) | ||
|---|---|---|
| type of concern | product conditions | reference |
| Classified as a low human health priority | Environment Canada Domestic Substance List | |
| show more | ||
Persistence and bioaccumulation | ||
|---|---|---|
| type of concern | product conditions | reference |
| Not suspected to be bioaccumulative | Environment Canada Domestic Substance List | |
Government, industry, academic studies and classifications |
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|---|---|---|
| government/industry list/academic study | appears on list as | classification(s) |
| FDA Food Additive Status | SODIUM BICARBONATE | • MISC • GRAS/FS • Cnd Peas - Part 155 • Cnd Tomato Paste - CFR155.191 • Cacao Prods - Part 163 • Cereal Flours - Part 137 • GRAS • GMP - CFR184.1736 • MISC • REG • Used to treat sodium methyl sulfate - CFR173.385 • SANI • REG - CFR178.1010(b)(41) • In animal feeds - CFR582.1736 |
| FDA Food Additive Status | BICARBONATE OF SODA | • B&N • GRAS/FS - CFR137.270 • Self-rising Cornmeal |
| Cosmetic Ingredient Review Assessments | SODIUM BICARBONATE | QQQ01,QQQ11; D-, M- |
| FDA Everything Added to Food | SODIUM BICARBONATE | • ASP |
| Environment Canada Domestic Substance List | CARBONIC ACID MONOSODIUM SALT | ,,Low-Health Priority,Y-Persistent,,,,,, |
| IFRA Fragrance Ingredient List | CARBONIC ACID MONOSODIUM SALT | reported as used in fragrance compounds in 2008 |
Other RTECS® classifications [shown for informational purposes only] |
||
|---|---|---|
| government/industry list/academic study | appears on list as | classification(s) |
| RTECS®- "Cutaneous Toxicity, Proceedings of the 3rd Conference, 1976," Drill, V 1977 | SODIUM BICARBONATE | • skin - Primary skin irritant ( human ) |
| RTECS®- American Journal of Diseases of Children 1981 | SODIUM BICARBONATE | • metabolic - Na (infant TDLo) • respiratory - Other changes (infant TDLo) • kidney or renal system - Urine volume increased (infant TDLo) |
| RTECS®- Carcinogenesis (London) 1988 | SODIUM BICARBONATE | • mutagenic - Positive mutation assay: Unscheduled DNA Synthesis (rat orl) |
| RTECS®- Carcinogenesis (London) 1988 | SODIUM BICARBONATE | • mutagenic - Positive mutation assay: Unscheduled DNA Synthesis (rat orl) |
| RTECS®- Drug and Chemical Toxicology 2005 | SODIUM BICARBONATE | • cardiovascular - Cardiomyopathy, including infarction (bird TDLo) • kidney or renal system - Changes in blood vessels or in circulation of kidney (bird TDLo) • kidney or renal system - Changes in both tubules and glomeruli (bird TDLo) • blood - Changes in erythrocyte (RBC) count (bird TDLo) • kidney or renal system - Changes in kidney weight (bird TDLo) • blood - Changes in serum composition (eg., TP, bilirubin, cholesterol) (bird TDLo) • blood - Changes in spleen (bird TDLo) • metabolic - Cl (bird TDLo) • biochemical - Effect on inflammation or mediation of inflammation (bird TDLo) • brain, nervous system, or behavioral effect - Fluid intake (bird TDLo) • brain, nervous system, or behavioral effect - Food intake (animal) (bird TDLo) • musculoskeletal - Joints (bird TDLo) • metabolic - K (bird TDLo) • kidney or renal system - Other changes (bird TDLo) • brain, nervous system, or behavioral effect - Somnolence (general depressed activity) (bird TDLo) • kidney or renal system - Structural or functional changes in ureter (bird TDLo) |
| RTECS®- Gigiena Truda i Professional'nye Zabolevaniya 1989 | SODIUM BICARBONATE | • metabolic - Na (rat TCLo) • broad systemic - Broad systemic toxicity (mouse LD50) • blood - Changes in serum composition (eg., TP, bilirubin, cholesterol) (rat TCLo) • cardiovascular - Other changes (rat TCLo) |
| RTECS®- Proceedings of the Oklahoma Academy of Science 1976 | SODIUM BICARBONATE | • reproductive - Other developmental abnormalities (mouse TDLo) |
| RTECS®- Toxicology and Applied Pharmacology 1964 | SODIUM BICARBONATE | • broad systemic - Broad systemic toxicity (rat LD50) |
| RTECS®- Toxicology 1982 | SODIUM BICARBONATE | • sense organ - Primary eye irritant (rabbit ) |
| RTECS®- Toxicology 1982 | SODIUM BICARBONATE | • sense organ - Primary eye irritant (rabbit ) |
references |
||
|---|---|---|
| government/industry list/academic study | reference | |
| FDA Food Additive Status | FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006. | |
| Cosmetic Ingredient Review Assessments | CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC. | |
| FDA Everything Added to Food | FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition. | |
| Environment Canada Domestic Substance List | EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry. | |
| IFRA Fragrance Ingredient List | IFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25 | |
| RTECS®- "Cutaneous Toxicity, Proceedings of the 3rd Conference, 1976," Drill, V 1977 [shown for informational purposes only] | RTECS®- "Cutaneous Toxicity, Proceedings of the 3rd Conference, 1976," Drill, V.A., and P. Lazar, eds., New York, Academic Press, Inc. 1977 -,127,1977 | |
| RTECS®- American Journal of Diseases of Children 1981 [shown for informational purposes only] | RTECS®- American Journal of Diseases of Children. (AMA, 535 N. Dearborn St., Chicago, IL 60610) V.1-80(3), 1911-50; V.100- 1960- 135,965,1981 | |
| RTECS®- Carcinogenesis (London) 1988 [shown for informational purposes only] | RTECS®- Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- 9,1203,1988 | |
| RTECS®- Carcinogenesis (London) 1988 [shown for informational purposes only] | RTECS®- Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 9,1203,1988 | |
| RTECS®- Drug and Chemical Toxicology 2005 [shown for informational purposes only] | RTECS®- Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1977/78- 28,245,2005 | |
| RTECS®- Gigiena Truda i Professional'nye Zabolevaniya 1989 [shown for informational purposes only] | RTECS®- Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI 33(5),30,1989 | |
| RTECS®- Proceedings of the Oklahoma Academy of Science 1976 [shown for informational purposes only] | RTECS®- Proceedings of the Oklahoma Academy of Science. (Oklahoma Academy of Science, c/o Executive Secretary-Treasurer, Southwestern Oklahoma State Univ., Weatherford, OK 73096) V.1- 1910/1920- 56,10,1976 | |
| RTECS®- Toxicology and Applied Pharmacology 1964 [shown for informational purposes only] | RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 6,726,1964 | |
| RTECS®- Toxicology 1982 [shown for informational purposes only] | RTECS®- Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- 23,281,1982 | |
| RTECS®- Toxicology 1982 [shown for informational purposes only] | RTECS®- Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 23,281,1982 | |
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