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SODIUM BENZOATE
Score
Data: Limited
CAS532-32-1
shampoo (303 products)
moisturizer (144 products)
conditioner (143 products)
body wash/ cleanser (143 products)
facial moisturizer/ treatment (142 products)
Show all 1,377 products that contain SODIUM BENZOATE.
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SODIUM BENZOATE


image source: PubChem
Health concerns of ingredient
About the ratings
Cancer no information
Developmental & reproductive toxicity no information
Allergies & immunotoxicity no information
Use restrictionsyes
Contamination concerns: none
Other MODERATE concerns: Organ system toxicity (non-reproductive)
Other LOW concerns: Data gaps

About the ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

Function/use(s): Fragrance Ingredient; Preservative; ANTICORROSIVE; MASKING

About SODIUM BENZOATE: Sodium benzoate is a preservative commonly used in foods, pharmaceuticals and cosmetics.

Synonym(s): BENZOIC ACID, SODIUM SALT; SODIUM SALT BENZOIC ACID; ANTIMOL; BENZOAN SODNY (CZECH) ; BENZOATE OF SODA; BENZOATE SODIUM; BENZOESAEURE (NA-SALZ) (GERMAN) ; SOBENATE; SODIUM BENZOIC ACID

Use restrictions

type of concern product conditions reference
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications   Cosmetic Ingredient Review Assessments

Organ system toxicity (non-reproductive)

type of concern product conditions reference
Limited evidence of sense organ toxicity    Harvell, J, 1994
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Data gaps

type of concern product conditions reference
Safety unknown for products that may be inhaled products that may be aerosolized (airborne) Cosmetic Ingredient Review Assessments
975 studies in PubMed science library may include information on the toxicity of this chemical see search results ->   PubMed

Multiple, additive exposure sources

type of concern product conditions reference
Designated as safe for general or specific, limited use in food   FDA Food Additive Status
Designated as safe for general or specific, limited use in food   FDA Everything Added to Food

Persistence and bioaccumulation

type of concern product conditions reference
Not suspected to be bioaccumulative    Environment Canada Domestic Substance List
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Ecotoxicology

type of concern product conditions reference
Not suspected to be an environmental toxin    Environment Canada Domestic Substance List

Government, industry, academic studies and classifications
government/industry list/academic study appears on list as classification(s)
FDA Food Additive StatusSODIUM BENZOATE• GRAS/FS
• < 0.1%
• Fruit Pres & Art Sw Fruit Jelly & Pres - CFR150.141; 150.161
• < 0.1%
• Margarine -166.110
• Conc. Orange Juice - CFR146.152; 146.154
• GRAS
• GMP - CFR184.1733
Association of Occupational and Environmental ClinicsSODIUM BENZOATE• o
Cosmetic Ingredient Review AssessmentsSODIUM BENZOATEQQQ02,QQQ36,QQQ14; M+, C-, R-, D-
FDA Everything Added to FoodSODIUM BENZOATE• ASP
Environment Canada Domestic Substance ListBENZOIC ACID, SODIUM SALT,,Low-Health Priority,,,,,,,
IFRA Fragrance Ingredient ListSODIUM BENZOATEreported as used in fragrance compounds in 2008
Harvell, J, 1994SODIUM BENZOATESkin or Sense Organ Toxicity Hazards: suspected

Other RTECS® classifications [shown for informational purposes only]
government/industry list/academic study appears on list as classification(s)
RTECS®- "Abdernalden's Handbuch der Biologischen Arbeitsmethoden 1935SODIUM BENZOATE• broad systemic - Broad systemic toxicity (frog LDLo)
RTECS®- Archives Internationales de Pharmacodynamie et de Therapie 1963SODIUM BENZOATE• brain, nervous system, or behavioral effect - Convulsions or effect on seizure threshold (rat TDLo)
• kidney or renal system - Other changes (rat TDLo)
RTECS®- Archives of Toxicology, Supplement 1980SODIUM BENZOATE• mutagenic - Positive mutation assay: Cytogenetic Analysis (hamster lng)
RTECS®- Archives of Toxicology, Supplement 1980SODIUM BENZOATE• mutagenic - Positive mutation assay: Cytogenetic Analysis (hamster lng)
RTECS®- Dermatologica 1984SODIUM BENZOATE• skin - Primary skin irritant ( human )
RTECS®- Dermatologica 1984SODIUM BENZOATE• skin - Primary skin irritant ( human )
RTECS®- Eisei Shikenjo Hokoku 1978SODIUM BENZOATE• reproductive - Homeostasis (rat TDLo)
• developmental - Musculoskeletal system (rat TDLo)
• reproductive - Viability index (rat TDLo)
RTECS®- FAO Nutrition Meetings Report Series 1974SODIUM BENZOATE• broad systemic - Broad systemic toxicity (rabbit LD50)
RTECS®- Gigiena i Sanitariya 1963SODIUM BENZOATE• broad systemic - Broad systemic toxicity (guinea pig LDLo)
RTECS®- Gigiena i Sanitariya 1986SODIUM BENZOATE• brain, nervous system, or behavioral effect - Changes in motor activity (specific assay) (mouse LD50)
• respiratory - Dyspnea (mouse LD50)
RTECS®- Journal of Industrial Hygiene and Toxicology 1948SODIUM BENZOATE• broad systemic - Broad systemic toxicity (rat LD50)
RTECS®- Journal of Pharmacology and Experimental Therapeutics 1956SODIUM BENZOATE• broad systemic - Broad systemic toxicity (mouse LD50)
RTECS®- Journal of the American Academy of Dermatology 1984SODIUM BENZOATE• skin - Primary skin irritant ( human )
RTECS®- Journal of the American Pharmaceutical Association, Scientific Edition 1942SODIUM BENZOATE• brain, nervous system, or behavioral effect - Convulsions or effect on seizure threshold (rat LD50)
• brain, nervous system, or behavioral effect - Tremor (rat LD50)
RTECS®- Kenkyu Nenpo--Tokyo-toritsu Eisei Kenkyusho 1991SODIUM BENZOATE• metabolic - Weight loss or decreased weight gain (rat TDLo)
• brain, nervous system, or behavioral effect - Convulsions or effect on seizure threshold (rat TDLo)
RTECS®- Medicinal Chemistry, A Series of Reviews 1963SODIUM BENZOATE• broad systemic - Broad systemic toxicity (mouse LD50)
RTECS®- Mutation Research 1990SODIUM BENZOATE• mutagenic - Positive mutation assay: Sister Chromatid Exchange ( human lym)
RTECS®- Mutation Research 1977SODIUM BENZOATE• mutagenic - Positive mutation assay: Cytogenetic Analysis (hamster fbr)
RTECS®- Mutation Research 1990SODIUM BENZOATE• mutagenic - Positive mutation assay: Sister Chromatid Exchange ( human lym)
RTECS®- Mutation Research 1977SODIUM BENZOATE• mutagenic - Positive mutation assay: Cytogenetic Analysis (hamster fbr)
RTECS®- Toxicology and Applied Pharmacology 1971SODIUM BENZOATE• reproductive - Fetal death (rat TDLo)
• reproductive - Fetotoxicity (rat TDLo)
RTECS®- Toxicology Letters 1993SODIUM BENZOATE• kidney or renal system - Changes in bladder weight (mouse TDLo)
• liver - Changes in liver weight (rat TDLo)
• blood - Changes in serum composition (eg., TP, bilirubin, cholesterol) (rat TDLo)
• biochemical - Other proteins (rat TDLo)

references
government/industry list/academic study reference
FDA Food Additive StatusFDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
Association of Occupational and Environmental ClinicsAOEC (Association of Occupational and Environmental Clinics). 2009. AEOC exposures codes and asthmagen designation.
Cosmetic Ingredient Review AssessmentsCIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
FDA Everything Added to FoodFDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
Environment Canada Domestic Substance ListEC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
IFRA Fragrance Ingredient ListIFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25
Scorecard.org Toxicity InformationHarvell, J., M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria).
RTECS®- "Abdernalden's Handbuch der Biologischen Arbeitsmethoden 1935 [shown for informational purposes only]RTECS®- "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig, Ger. Dem. Rep.) 4,1313,1935
RTECS®- Archives Internationales de Pharmacodynamie et de Therapie 1963 [shown for informational purposes only]RTECS®- Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- 144,120,1963
RTECS®- Archives of Toxicology, Supplement 1980 [shown for informational purposes only]RTECS®- Archives of Toxicology, Supplement. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) No.1- 1978- 4,41,1980
RTECS®- Archives of Toxicology, Supplement 1980 [shown for informational purposes only]RTECS®- Archives of Toxicology, Supplement. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) No.1- 4,41,1980
RTECS®- Dermatologica 1984 [shown for informational purposes only]RTECS®- Dermatologica. (S. Karger Pub., Inc., 79 Fifth Ave., New York, NY 10003) V.79- 1939- 26,734,1984
RTECS®- Dermatologica 1984 [shown for informational purposes only]RTECS®- Dermatologica. (S. Karger Pub., Inc., 79 Fifth Ave., New York, NY 10003) V.79- 26,734,1984
RTECS®- Eisei Shikenjo Hokoku 1978 [shown for informational purposes only]RTECS®- Eisei Shikenjo Hokoku. Bulletin of the Institute of Hygienic Sciences. (Kokuritsu Eisei Shikenjo Kagaku, 18-1 Bushitsu Johobu, Setagaya-ku, Tokyo 158, Japan) V.1- 1886- (96),47,1978
RTECS®- FAO Nutrition Meetings Report Series 1974 [shown for informational purposes only]RTECS®- FAO Nutrition Meetings Report Series. (Rome, Italy) No.?-57, 1948-77. Discontinued. 53A,34,1974
RTECS®- Gigiena i Sanitariya 1963 [shown for informational purposes only]RTECS®- Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- 28(1),45,1963
RTECS®- Gigiena i Sanitariya 1986 [shown for informational purposes only]RTECS®- Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- 51(1),75,1986
RTECS®- Journal of Industrial Hygiene and Toxicology 1948 [shown for informational purposes only]RTECS®- Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. 30,63,1948
RTECS®- Journal of Pharmacology and Experimental Therapeutics 1956 [shown for informational purposes only]RTECS®- Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- 117,307,1956
RTECS®- Journal of the American Academy of Dermatology 1984 [shown for informational purposes only]RTECS®- Journal of the American Academy of Dermatology. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63141) 1979- 26,734,1984
RTECS®- Journal of the American Pharmaceutical Association, Scientific Edition 1942 [shown for informational purposes only]RTECS®- Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. 31,253,1942
RTECS®- Kenkyu Nenpo--Tokyo-toritsu Eisei Kenkyusho 1991 [shown for informational purposes only]RTECS®- Kenkyu Nenpo--Tokyo-toritsu Eisei Kenkyusho. Annual Report of Tokyo Metropolitan Research Laboratory of Public Health. (Tokyo-toritsu Eisei Kenkyusho, 24-1, 3-chome, Hyakunin-cho, Shin-juku-ku, Tokyo 160, Japan) V.1- 1949/50- 42,285,1991
RTECS®- Medicinal Chemistry, A Series of Reviews 1963 [shown for informational purposes only]RTECS®- Medicinal Chemistry, A Series of Reviews. (New York, NY) V.1-6, 1951-63. Discontinued. 6,290,1963
RTECS®- Mutation Research 1990 [shown for informational purposes only]RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 241,109,1990
RTECS®- Mutation Research 1977 [shown for informational purposes only]RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 48,337,1977
RTECS®- Mutation Research 1990 [shown for informational purposes only]RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- -1964 241,109,1990
RTECS®- Mutation Research 1977 [shown for informational purposes only]RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- -1964 48,337,1977
RTECS®- Toxicology and Applied Pharmacology 1971 [shown for informational purposes only]RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 19,373,1971
RTECS®- Toxicology Letters 1993 [shown for informational purposes only]RTECS®- Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- 69,171,1993

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