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SILICA, AMORPHOUS
Score
Data: Good
CAS7631-86-9
eye shadow (674 products)
lipstick (498 products)
foundation (406 products)
nail polish (403 products)
lip gloss (298 products)
Show all 3,733 products that contain SILICA, AMORPHOUS.
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SILICA, AMORPHOUS


image source: PubChem
Health concerns of ingredient
About the ratings
Canceryes
Developmental & reproductive toxicity no information
Allergies & immunotoxicity no information
Use restrictions no information
Contamination concerns: none
Other HIGH concerns: Persistence and bioaccumulation
Other MODERATE concerns: Organ system toxicity (non-reproductive)

About the ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

Function/use(s): Abrasive; Absorbent; Anticaking Agent; Bulking Agent; Opacifying Agent; Suspending Agent- Nonsurfactant

About SILICA, AMORPHOUS: Silica is the most common constituent of sand. Fine silica, typically used in industrial applications and inhaled by workers, is associated with a wide range of disorders, particularly affecting the l ... read more

Synonym(s): SILICA, AMORPHOUS SILICA; AMORPHOUS SILICON OXIDE HYDRATE; SILICIC ANHYDRIDE; SILICON DIOXIDE; SILICON DIOXIDE, FUMED; SPHERON P-1000; SPHERON PL-700; FUMED SILICON DIOXIDE; ROSE ABSOLUTE; SILICON DIOXIDE; ACCUSAND

Persistence and bioaccumulation

type of concern product conditions reference
Persistent, bioaccumulative in wildlife and humans products that may be aerosolized (airborne)  National Library of Medicine HazMap
Persistent, bioaccumulative in wildlife products that may be aerosolized (airborne)  National Library of Medicine HazMap
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Organ system toxicity (non-reproductive)

type of concern product conditions reference
Limited evidence of kidney toxicity products that may be aerosolized (airborne)  Landrigan, P, 1984
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Cancer

type of concern product conditions reference
Cancer - not classifiable/not likely to be human carcinogen products that may be aerosolized (airborne)  Int'l Agency for Research on Cancer (IARC) - Carcinogens

Data gaps

type of concern product conditions reference
49,935 studies in PubMed science library may include information on the toxicity of this chemical see search results ->   PubMed

Multiple, additive exposure sources

type of concern product conditions reference
Designated as safe for general or specific, limited use in food products that may be aerosolized (airborne) FDA Everything Added to Food
Designated as safe for general or specific, limited use in food products that may be aerosolized (airborne) FDA Food Additive Status

Ecotoxicology

type of concern product conditions reference
Not suspected to be an environmental toxin    Environment Canada Domestic Substance List

Government, industry, academic studies and classifications
government/industry list/academic study appears on list as classification(s)
FDA Food Additive StatusSILICON DIOXIDE• AC
• REG
• < 2.0% by wt of food - Used only in those foods where anticaking effect is demonstrated 172.480
• REG
• < 2% by wt of feed - In feed & feed components as anticaking or grinding agent - CFR573.940 for use limit
• FS
• < 1.0% by wt of finished food - In dr
Association of Occupational and Environmental ClinicsSILICA, AMORPHOUS• o
FDA Everything Added to FoodSILICON DIOXIDE• ASP
Environment Canada Domestic Substance ListSILICA,,Low-Health Priority,Y-Persistent,,,,,,
IFRA Fragrance Ingredient ListSILICAreported as used in fragrance compounds in 2008
National Library of Medicine HazMapSILICA, AMORPHOUSSD: No;FI: Yes;BA: Yes;TL: 10 mg/m3, inhal. fraction, 3 mg/m3, respir. fraction(diatomaceous earth uncalcined), 10 mg/m3(precipitated silica, silica gel), 2 mg/m3, respir. fraction(silica fume), 0.1 mg/m3, respir. fraction(silica fused);ID: 3000 mg/m3;MA:
National Library of Medicine HazMapSILICA, AMORPHOUSSD: No;FI: Yes;BA: Yes;TL: 10 mg/m3, inhal. fraction, 3 mg/m3, respir. fraction(diatomaceous earth uncalcined), 10 mg/m3(precipitated silica, silica gel), 2 mg/m3, respir. fraction(silica fume), 0.1 mg/m3, respir. fraction(silica fused);ID: 3000 mg/m3;MA:
National Library of Medicine HazMapSILICA, AMORPHOUSSD: No;FI: Yes;BA: Yes;TL: 10 mg/m3, inhal. fraction, 3 mg/m3, respir. fraction(diatomaceous earth uncalcined), 10 mg/m3(precipitated silica, silica gel), 2 mg/m3, respir. fraction(silica fume), 0.1 mg/m3, respir. fraction(silica fused);ID: 3000 mg/m3;MA:
National Library of Medicine HazMapSILICA, AMORPHOUSSD: No;FI: Yes;BA: Yes;TL: 10 mg/m3, inhal. fraction, 3 mg/m3, respir. fraction(diatomaceous earth uncalcined), 10 mg/m3(precipitated silica, silica gel), 2 mg/m3, respir. fraction(silica fume), 0.1 mg/m3, respir. fraction(silica fused);ID: 3000 mg/m3;MA:
National Library of Medicine HazMapSILICA, AMORPHOUSSD: No;FI: Yes;BA: Yes;TL: 10 mg/m3, inhal. fraction, 3 mg/m3, respir. fraction(diatomaceous earth uncalcined), 10 mg/m3(precipitated silica, silica gel), 2 mg/m3, respir. fraction(silica fume), 0.1 mg/m3, respir. fraction(silica fused);ID: 3000 mg/m3;MA:
Int'l Agency for Research on Cancer (IARC) - CarcinogensSILICA, AMORPHOUSIARC GROUP 3
Dossing, M, 1985SILICAGastrointestinal or Liver Toxicity Hazards: suspected
A Relational Database of Hazardous Chemicals and Occupational DiseasesSILICARespiratory Toxicity Hazards: suspected
Landrigan, P, 1984SILICAKidney Toxicity Hazards: suspected

Other RTECS® classifications [shown for informational purposes only]
government/industry list/academic study appears on list as classification(s)
RTECS®- National Technical Information Service 7804SILICA, AMORPHOUS• sense organ - Primary eye irritant (rabbit )
RTECS®- National Technical Information Service 7804SILICA, AMORPHOUS• metabolic - Other changes (rat LDLo)
• sense organ - Primary eye irritant (rabbit )
RTECS®- Toxicologist 2002SILICA, AMORPHOUS• biochemical - Effect on inflammation or mediation of inflammation (rat TDLo)
• respiratory - Other changes (rat TDLo)

references
government/industry list/academic study reference
FDA Food Additive StatusFDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
Association of Occupational and Environmental ClinicsAOEC (Association of Occupational and Environmental Clinics). 2009. AEOC exposures codes and asthmagen designation.
FDA Everything Added to FoodFDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
Environment Canada Domestic Substance ListEC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
IFRA Fragrance Ingredient ListIFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25
National Library of Medicine HazMapNLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
Int'l Agency for Research on Cancer (IARC) - CarcinogensIARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures).
Scorecard.org Toxicity InformationDossing, M. and P. Skinhoj. Occupational Liver Injury. Present State of Knowledge and Future Perspectives. International Archives of Occupational and Environmental Health. 56:1-21. 1985. (Table 2: Chemically induced liver injury: morphologic features and examples of confirmed and suspected causative agents).
Scorecard.org Toxicity InformationA Relational Database of Hazardous Chemicals and Occupational Diseases. Browse Haz-Map by Adverse Effects http://hazmap.nlm.nih.gov/hazmapadv.html; Klaassen, C., M. Amdur and J. Doull (eds.). Casarett and Doull
Scorecard.org Toxicity InformationLandrigan, P.J., Goyer, R.A. Clarkson, T.W., Sandler, D.P., Smith, J.H., Thun, M.J., and R. Wedeen. The Work-Relatedness of Renal Disease. Archives of Environmental Health. 39(3): 225-230. 1984. (Table 2: Estimated Numbers of Workers in the United States with Potential Occupational Exposures to Known or Suspect Nephrotoxins).
RTECS®- National Technical Information Service 7804 [shown for informational purposes only]RTECS®- National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. OTS0537804
RTECS®- National Technical Information Service 7804 [shown for informational purposes only]RTECS®- National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. OTS0537804
RTECS®- Toxicologist 2002 [shown for informational purposes only]RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 66,353,2002

"RTECS®" is a United States trademark owned and licensed under authority of the U.S. Government, by and through MDL Information Systems, Inc.