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SELENIUM


image source: PubChem
Health Concerns of the Ingredient:
Overall Hazard
 
 
 
 
 
Allergies & immunotoxicity
 
 

About SELENIUM: Any ingredient that contains selenium as component either as a salt or metal.

Synoym(s): SE; SELENIUM (TOTAL) ; SELENIUM, DISSOLVED; C.I. 77805; COLLOIDAL SELENIUM; ELEMENTAL SELENIUM; SELEN (POLISH) ; SELENATE; SELENIUM (ACGIH) ; SELENIUM ALLOY; SELENIUM BASE

Use restrictions

Concern Reference
Violation of government restrictions - Banned or found unsafe for use in cosmeticsCanada - Prohibited and Restricted Cosmetics Ingredients
Violation of government restrictions - Banned or found unsafe for use in cosmeticsJapan's Standards for Cosmetics

Organ system toxicity (non-reproductive)

Concern Reference
Known human respiratory toxicantEPA Hazardous Air Pollutants
Classified as toxic or harmful (only for products for use around the mouth; products for use on the lips; products that may be aerosolized (airborne))European Union - Classification & Labelling
Limited evidence of gastrointestinal or liver toxicityNational Library of Medicine HazMap
Limited evidence of sense organ toxicityAgency for Toxic Substances and Disease Registry
Limited evidence of musculoskeletal toxicity US EPA, Air Risk Information Support Center
Limited evidence of respiratory toxicity (only for products that may be aerosolized (airborne))US EPA, Air Risk Information Support Center
Limited evidence of cardiovascular or blood toxicityKlaassen, C
Limited evidence of gastrointestinal or liver toxicityCalifornia EPA, Office of Environmental Health Hazard Assessment
Limited evidence of musculoskeletal toxicityUS EPA, Air Risk Information Support Center
Limited evidence of sense organ toxicityUS EPA, Air Risk Information Support Center
Limited evidence of respiratory toxicityUS EPA, Air Risk Information Support Center
Limited evidence of kidney toxicityMerck & Co
Limited evidence of cardiovascular or blood toxicityCalifornia EPA, Office of Environmental Health Hazard Assessment
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)EPA Toxic Release Inventory PBTs
reproductive - weight of evidence unknown/unassessed/unreview: published lit review or major tox studyNational Library of Medicine HazMap
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

Concern Reference
Persistent, bioaccumulative in wildlife and humansNational Library of Medicine HazMap
Persistent, bioaccumulative in wildlifeNational Library of Medicine HazMap
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Developmental/reproductive toxicity

Concern Reference
Limited evidence of reproductive toxicityNational Library of Medicine HazMap
Limited evidence of developmental toxicityUS EPA
Limited evidence of reproductive toxicityUS EPA

Cancer

Concern Reference
Cancer - limited evidenceUS EPA, Air Risk Information Support Center
Cancer - not classifiable/not likely to be human carcinogenEPA Integrated Risk Information System (IRIS)
Cancer - not classifiable/not likely to be human carcinogenInt'l Agency for Research on Cancer (IARC) - Carcinogens

Occupational hazards

Concern Reference
Allowed workplace exposures restricted to low dosesEuropean Union - Classification & Labelling
Strong evidence of occupational hazardsEuropean Union - Classification & Labelling

Ecotoxicology

Concern Reference
Wildlife and environmental toxicityEuropean Union - Classification & Labelling
Wildlife and environmental toxicityEPA Clean Water Act - Priority Pollutants
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Data gaps

Concern Reference
Insufficient data to determine safetyEPA Integrated Risk Information System (IRIS)
93,786 studies in PubMed science library may include information on the toxicity of this chemical see search results ->NLM PubMed

Data Sources

US EPA, Air Risk Information Support Center. Health Effects Notebook for Hazardous Air Pollutants. http://www.epa.gov/ttnatw01/hlthef/hapindex.html
AOEC (Association of Occupational and Environmental Clinics). 2009. AEOC exposures codes and asthmagen designation.
Agency for Toxic Substances and Disease Registry. Minimal risk Levels for Hazardous Substances. January 2004. http://www.atsdr.cdc.gov/mrls.html; US EPA, Air Risk Information Support Center. Health Effects Notebook for Hazardous Air Pollutants. http://www.epa.gov/ttnatw01/hlthef/hapindex.html
CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
California EPA, Office of Environmental Health Hazard Assessment. Air Toxics Hot Spots Program Risk Assessment Guidelines, Part III: Technical Support Document "Determination of Noncancer Chronic Reference Exposure Levels". Includes all Chronic Reference Exposure Levels (CRELs) adopted by OEHHA as of August 2003 (http://www.oehha.ca.gov/air/chronic_rels/AllChrels.html, plus draft CRELS proposed through March 2004 (http://www.oehha.ca.gov/air/chronic_rels/index.html.
California EPA, Office of Environmental Health Hazard Assessment. Air Toxics Hot Spots Program Risk Assessment Guidelines, Part III: Technical Support Document 'Determination of Noncancer Chronic Reference Exposure Levels'. Includes all Chronic Reference Exposure Levels (CRELs) adopted by OEHHA as of August 2003 (http://www.oehha.ca.gov/air/chronic_rels/AllChrels.html, plus draft CRELS proposed through March 2004 (http://www.oehha.ca.gov/air/chronic_rels/index.html.
California EPA, Office of Environmental Health Hazard Assessment. Air Toxics Hot Spots Program Risk Assessment Guidelines, Part III: Technical Support Document 'Determination of Noncancer Chronic Reference Exposure Levels'. Includes all Chronic Reference Exposure Levels (CRELs) adopted by OEHHA as of August 2003 (http://www.oehha.ca.gov/air/chronic_rels/AllChrels.html, plus draft CRELS proposed through March 2004 (http://www.oehha.ca.gov/air/chronic_rels/index.html.
EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
EPA (U.S. Environmental Protection Agency). 2005. Office of Air. The 112(b)1 Hazardous Air Pollutants List (as modified). Last modified: 12 Dec 2005.
EPA (U.S. Environmental Protection Agency). 2008. Integrated Risk Information System (IRIS). Evidence for human carcinogenicity based on 1986-2005 guidelines.
European Commission. 2013. Cosing, the European Commission database with information on cosmetic substances and ingredients. Accessed on March 1, 2013 at http://ec.europa.eu/consumers/cosmetics/cosing/ .
Health Canada. 2007. List of Prohibited and Restricted Cosmetic Ingredients. Canada's Cosmetic Ingredient Hotlist. March 2007.
IARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures).
Japan Ministry of Health, Labour and Welfare. 2006. Standards for Cosmetics. Evaluation and Licensing Division. Pharmaceutical and Food Safety Bureau.
Klaassen, C., M. Amdur and J. Doull (eds.). Casarett and Doull's Toxicology. The Basic Science of Poisons, 5th Ed. Pergamon Press, NY. 1996.;California EPA, Office of Environmental Health Hazard Assessment. Air Toxics Hot Spots Program Risk Assessment Guidelines, Part III: Technical Support Document "Determination of Noncancer Chronic Reference Exposure Levels". Includes all Chronic Reference Exposure Levels (CRELs) adopted by OEHHA as of August 2003 (http://www.oehha.ca.gov/air/chronic_rels/AllChrels.html, plus draft CRELS proposed through March 2004 (http://www.oehha.ca.gov/air/chronic_rels/index.html.
Merck & Co. The Merck Manual of Diagnosis and Therapy. TABLE 226-1. Common Nephrotoxic Agents http://www.merck.com/pubs/mmanual/tables/226tb1.htm
NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
US EPA, Air Risk Information Support Center. Health Effects Notebook for Hazardous Air Pollutants. http://www.epa.gov/ttnatw01/hlthef/hapindex.html
US EPA, Air Risk Information Support Center. Health Effects Notebook for Hazardous Air Pollutants. http://www.epa.gov/ttnatw01/hlthef/hapindex.html
US EPA, Air Risk Information Support Center. Health Effects Notebook for Hazardous Air Pollutants. http://www.epa.gov/ttnatw01/hlthef/hapindex.html
US EPA, Air Risk Information Support Center. Health Effects Notebook for Hazardous Air Pollutants. http://www.epa.gov/ttnatw01/hlthef/hapindex.html, A Relational Database of Hazardous Chemicals and Occupational Diseases. Browse Haz-Map by Adverse Effects http://hazmap.nlm.nih.gov/hazmapadv.html
US EPA, Air Risk Information Support Center. Health Effects Notebook for Hazardous Air Pollutants. http://www.epa.gov/ttnatw01/hlthef/hapindex.html;A Relational Database of Hazardous Chemicals and Occupational Diseases. Browse Haz-Map by Adverse Effects http://hazmap.nlm.nih.gov/hazmapadv.html;Nemery, B. Metal Toxicity and the Respiratory Tract. European Respiratory Journal. 3(2): 202-219. 1990.(Table 1: Summary of pulmonary toxicity of metals).
US EPA. Roadmaps to Sources of Information on Chemicals Listed in the Emergency Planning Community and Community Right-to-Know Act (Also Known as SARA Title 3), Section 313 Toxic Release Inventory (for Microcomputers). (Report Number EPADFDK92040). 1991. Data file distributed in 2 diskettes by Office of Pollution, Prevention, and Toxics, Environmental Protection Agency, Washington, DC. NOTE: Datasource no longer being maintained by EPA; not currently available online.
US EPA. Roadmaps to Sources of Information on Chemicals Listed in the Emergency Planning Community and Community Right-to-Know Act (Also Known as SARA Title 3), Section 313 Toxic Release Inventory (for Microcomputers). (Report Number EPADFDK92040). 1991. Data file distributed in 2 diskettes by Office of Pollution, Prevention, and Toxics, Environmental Protection Agency, Washington, DC. NOTE: Datasource no longer being maintained by EPA; not currently available online.;Frazier , L. and M. L. Hage (eds.). Reproductive Hazards of the Workplace, Wiley Europe, 1998. Table 10 (Partial List of Reproductive Toxicants) available at http://www.pharmacy.ohio-state.edu/homepage/safety/chemhygiene_table_repro.pdf.; A Relational Database of Hazardous Chemicals and Occupational Diseases. Browse Haz-Map by Adverse Effects http://hazmap.nlm.nih.gov/hazmapadv.html.
{Beani, 1994}

About the ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer