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SACCHAROMYCES/ MANGANESE FERMENT

Health Concerns of the Ingredient:
Overall Hazard
 
 
Cancer
 
 
 
Allergies & immunotoxicity
 
 
Use restrictions
 
 
Other HIGH concerns: Persistence and bioaccumulation; Other LOW concerns: Data gaps, Organ system toxicity (non-reproductive)

About SACCHAROMYCES/ MANGANESE FERMENT: Saccharomyces/Manganese Ferment is an extract of a fermentation product ofsaccharomyces in the presence of manganese ions.

Function(s): Not Reported; SKIN CONDITIONING

Synonym(s): SACCHAROMYCES/MANGANESE FERMENT,

Developmental/reproductive toxicity

Concern Reference
Limited evidence of reproductive toxicityNational Library of Medicine HazMap

Persistence and bioaccumulation

Concern Reference
Persistent, bioaccumulative in wildlife and humansNational Library of Medicine HazMap
Persistent, bioaccumulative in wildlifeNational Library of Medicine HazMap

Organ system toxicity (non-reproductive)

Concern Reference
Limited evidence of respiratory toxicityNational Library of Medicine HazMap
Limited evidence of respiratory toxicity (only for products that may be aerosolized (airborne))US EPA, Air Risk Information Support Center
Limited evidence of gastrointestinal or liver toxicityKlaassen, C
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)EPA Toxic Release Inventory PBTs
reproductive - weight of evidence unknown/unassessed/unreview: published lit review or major tox studyNational Library of Medicine HazMap

Data gaps

Concern Reference
Insufficient data to determine safetyEPA Integrated Risk Information System (IRIS)

Enhanced skin absorption

Concern Reference
Absorbs into the skinAPCP

Neurotoxicity

Concern Reference
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox studyNational Library of Medicine HazMap

Cancer

Concern Reference
Cancer - not classifiable/not likely to be human carcinogenEPA Integrated Risk Information System (IRIS)

Multiple, additive exposure sources

Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status

Data Sources

APCP. 2007. Acqua-Biomin® Product Line: Technical Information. South Plainfield, NJ: Arch Personal Care Products, 8.
APCP. 2007. Acqua-Biomin® Product Line: Technical Information. South Plainfield, NJ: Arch Personal Care Products, 8. [accessed at http://www.archchemicals.com/Fed/PC/Docs/Acqua-Biomin_v1.0.pdf].
EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
EPA (U.S. Environmental Protection Agency). 2008. Integrated Risk Information System (IRIS). Evidence for human carcinogenicity based on 1986-2005 guidelines.
FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
Klaassen, C., M. Amdur and J. Doull (eds.). Casarett and Doull's Toxicology. The Basic Science of Poisons, 5th Ed. Pergamon Press, NY. 1996., Malachowsky, M.J. Health Effects of Toxic Substances. Government Institutes. Rockville, MD 1995.
NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
US EPA, Air Risk Information Support Center. Health Effects Notebook for Hazardous Air Pollutants. http://www.epa.gov/ttnatw01/hlthef/hapindex.html, A Relational Database of Hazardous Chemicals and Occupational Diseases. Browse Haz-Map by Adverse Effects http://hazmap.nlm.nih.gov/hazmapadv.html, Klaassen, C., M. Amdur and J. Doull (eds.). Casarett and Doull

About the ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer