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Data available:
 
Fair

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PROPYLENE GLYCOL


image source: PubChem
Health Concerns of the Ingredient:
Overall Hazard
 
 
Cancer
 
 
Developmental &
reproductive toxicity
 
 
 
Other HIGH concerns: Irritation (skin, eyes, or lungs); Other MODERATE concerns: Organ system toxicity (non-reproductive); Other LOW concerns: Enhanced skin absorption, Data gaps

About PROPYLENE GLYCOL: Propylene glycol is a small organic alcohol commonly used as a skin conditioning agent. It has been associated with irritant and allergic contact dermatitis as well as contact urticaria in humans; the ... read more

Function(s): Fragrance Ingredient; Humectant; Skin-Conditioning Agent - Humectant; Skin-ConditioningAgent - Miscellaneous; Solvent; Viscosity Decreasing Agent; SKIN CONDITIONING; VISCOSITY CONTROLLING

Synonym(s): 1,2-DIHYDROXYPROPANE; 1,2-PROPANEDIOL; 2-HYDROXYPROPANOL; METHYLETHYL GLYCOL; PROPANE-1,2-DIOL; 1,2-DIHYDROXYPROPANE; 1,2-PROPYLENE GLYCOL; 1,2-PROPYLENGLYKOL (GERMAN) ; ALPHA-PROPYLENEGLYCOL; DOWFROST; METHYLETHYLENE GLYCOL

Allergies/immunotoxicity

Concern Reference
Limited evidence of skin and immune system toxicity or allergiesCIR (Cosmetic Ingredient Review)

Organ system toxicity (non-reproductive)

Concern Reference
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List

Irritation (skin, eyes, or lungs)

Concern Reference
Classified as skin irritantNational Library of Medicine HazMap

Use restrictions

Concern Reference
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualificationsCosmetic Ingredient Review Assessments

Enhanced skin absorption

Concern Reference
Penetration enhancerCosmetic Ingredient Review Assessments

Developmental/reproductive toxicity

Concern Reference
Not likely to be a toxicant in humansNTP - Risks to Human Reproduction

Data gaps

Concern Reference
Safety assessment was based on related chemicalCosmetic Ingredient Review Assessments
4,760 studies in PubMed science library may include information on the toxicity of this chemical see search results ->NLM PubMed

Multiple, additive exposure sources

Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Data Sources

CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
IFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25
NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
NTP (National Toxicology Program). 2006. NTP Center for the Evaluation fo Risks to Human Reproduction (CERHR). NTP-CERHR Reports and Monographs.

About the ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer