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Score:
Data available:
 
Fair

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PCA


image source: PubChem
Health Concerns of the Ingredient:
Overall Hazard
 
 
Cancer
 
 
Developmental &
reproductive toxicity
 
 
 
Other HIGH concerns: Contamination concerns; Other LOW concerns: Ecotoxicology, Organ system toxicity (non-reproductive)

About PCA: PCA is a cyclic organic compound.

Function(s): Skin-Conditioning Agent - Humectant; MOISTURISING

Synoym(s): CHLORIDAZON; GLUTIMIC ACID; 5-OXOPROLINE; AJIDEW A-100; BAS 1191611; BAS 13033; BUREX (CZECH) ; CHLORIDAZON; CHLORIDAZONE; CURBETAN; GLUTIMIC ACID

Allergies/immunotoxicity

Concern Reference
Limited evidence of immune system toxicity or allergies (only for products for use on skin)European Union - Classification & Labelling
Limited evidence of immune system toxicity or allergiesEuropean Economic Community

Use restrictions

Concern Reference
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualificationsCosmetic Ingredient Review Assessments

Organ system toxicity (non-reproductive)

Concern Reference
Limited evidence of sense organ toxicityEuropean Economic Community

Ecotoxicology

Concern Reference
Wildlife and environmental toxicityEuropean Union - Classification & Labelling

Data gaps

Concern Reference
20,912 studies in PubMed science library may include information on the toxicity of this chemical see search results ->NLM PubMed

Contamination concerns

Impurity Score
NITROSAMINES
Data: Fair

Data Sources

CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
European Economic Community. Sensitizing Substances in the EEC List of Dangerous Substances. Annex I to Council Directive 67/548/EEC. http://www.kemi.se/default_eng.cfm?page=klass_mark/klasshem_eng.htm
European Economic Community. Sensitizing Substances in the EEC List of Dangerous Substances. Annex I to Council Directive 67/548/EEC. http://www.kemi.se/default_eng.cfm?page=klass_mark/klasshem_eng.htm
NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

About the ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer