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Data: Limited

Panthenol

IMAGE SOURCE: PubChem

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Other Concerns

Multiple, additive exposure sources (low)

SYNONYMS

● 2,4-DIHYDROXY-N-(3-HYDROXYPROPYL)-3,3-DIMETHYL- BUTANAMIDE
● 2,4-DIHYDROXY-N-(3-HYDROXYPROPYL)-3,3-DIMETHYLBUTANAMIDE
● BUTANAMIDE, 2,4-DIHYDROXY-N-(3-HYDROXYPROPYL)-3,3-DIMETHYL-
● BUTANAMIDE, 2,4DIHYDROXYN(3HYDROXYPROPYL)3,3DIMETHYL,(+/)
● D-PANTOTHENYL ALCOHOL
● DEXPANTHENOL
● DL-PANTOTHENYL ALCOHOL
● PANTHENOL
● PANTHENOL , DL-FORM
● PANTOTHENOL
● PANTOTHENYL ALCOHOL
● PROVITAMIN B5

Restricted

Restricted: EWG VERIFIED products cannot contain this ingredient without adequate substantiation


Panthenol is a form of vitamin B5, used as a moisturizer and lubricating compound. This ingredient is listed in the PETA's Caring Consumer guide as a substance that can be of either animal or plant origin.

Common concerns

See how this product scores for common concerns.

  • LOW
    Cancer
  • LOW
    Allergies & Immunotoxicity
  • LOW
    Developmental and Reproductive Toxicity
  • LOW
    Use Restrictions

Ingredient concerns

  • CONCERNS
  • DATA SOURCES

Products with this Ingredient

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shampoo980 products
conditioner956 products
facial moisturizer/treatment437 products
hair treatment/serum384 products
moisturizer376 products
mask338 products
hair styling aide279 products
body wash/cleanser247 products
serums & essences242 products
mascara240 products
foundation223 products
facial cleanser194 products
hair spray162 products
styling gel/lotion157 products
brow liner148 products
around-eye cream139 products
daily use with SPF98 products
recreational sunscreen98 products
toners/astringents87 products
concealer75 products
sunless tanning67 products
styling mousse/foam64 products
exfoliant/scrub63 products
detangler52 products
antiperspirant/deodorant50 products
nail polish47 products
liquid hand soap43 products
CC cream42 products
hand cream41 products
makeup remover40 products
hair color and bleaching39 products
makeup primer38 products
anti-aging37 products
bubble bath36 products
setting powder/spray36 products
shaving cream33 products
baby lotion30 products
polish remover30 products
bar soap29 products
baby shampoo28 products
body firming lotion23 products
eye shadow21 products
baby soap21 products
after shave20 products
lip balm19 products
18 products
damaged skin treatment16 products
body spray16 products
facial powder14 products
eye liner14 products
bronzer/highlighter13 products
hair-loss treatment13 products
baby sunscreen11 products
nail treatment10 products
shaving cream (men's)10 products
beard cleanser10 products
beard care10 products
diaper cream9 products
after sun product9 products
tanning oil9 products
body oil8 products
lipstick7 products
hand sanitizer7 products
BB cream7 products
other eye makeup6 products
bath oil/salts/soak6 products
foot moisturizer5 products
lip balm with SPF5 products
cuticle treatment4 products
skin fading/lightener4 products
blush4 products
fragrance for men4 products
foot odor control3 products
nail glue3 products
facial cleansing wipes3 products
makeup removing wipes3 products
baby bubble bath2 products
baby wipes2 products
foot cleansing2 products
pore strips2 products
baby oil2 products
lip plumper2 products
oil controller1 products
antiperspirant/deodorant (men's)1 products
eye makeup remover1 products
muscle/joint soreness1 products
lip gloss1 products
depilatory1 products
lip liner1 products
eyelash glue1 products
vapor rubs1 products
body cleansing wipes1 products

Multiple, additive exposure sources

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CONCERN REFERENCE
Used in food or as an additive with limited or no toxicity information availableFDA Everything Added to Food

Data gaps

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CONCERN REFERENCE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
326 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Informational

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CONCERN REFERENCE
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review Assessments

Ecotoxicology

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CONCERN REFERENCE
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Organ system toxicity (non-reproductive)

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CONCERN REFERENCE
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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CONCERN REFERENCE
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.

HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED® mark means a product meets EWG’s strictest criteria for transparency and health.

Score legend

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST
Low Availability
Moderate Availability
High Availability

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