PANTHENOL || Skin Deep® Cosmetics Database | Environmental Working Group

PANTHENOL

Score	Data: Limited
CAS	16485-10-2
conditioner (629 products)
shampoo (525 products)
mascara (497 products)
facial moisturizer/ treatment (391 products)
hair color and bleaching (386 products)
Show all 4,478 products that contain PANTHENOL.
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PANTHENOL

image source: PubChem

Health concerns of ingredient
About the ratings
Cancer	no information
Developmental & reproductive toxicity	no information
Allergies & immunotoxicity	no information
Use restrictions	no information
Contamination concerns: none
Other HIGH concerns: Multiple, additive exposure sources
Other LOW concerns: Data gaps

About the ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

Function/use(s): Hair Conditioning Agent; ANTISTATIC; SKIN CONDITIONING

About PANTHENOL: Panthenol is a form of vitamin B5, used as a moisturizer and lubricating compound. This ingredient is listed in the PETA's Caring Consumer guide as a substance that can be of either animal or plant or ... read more

Synonym(s): DEXPANTHENOL; PANTOTHENOL; PANTOTHENYL ALCOHOL; D-PANTOTHENYL ALCOHOL; DL-PANTOTHENYL ALCOHOL; PROVITAMIN B5; PANTHENOL , DL-FORM; (+-) -PANTOTHENYL ALCOHOL; ALCOOL DL-PANTOTENILICO (ITALIAN) ; DL-PANTOTHENYL ALCOHOL; PANTENOL

This ingredient may be derived from animals. From PETA's Caring Consumer: Can come from animal or plant sources or synthetics. In shampoos, supplements, emollients, etc. In foods. Derivative: Panthenyl. Alternatives: synthetics, plants.

Multiple, additive exposure sources
type of concern	product conditions	reference
Used in food or as an additive with limited or no toxicity information available		FDA Everything Added to Food

Data gaps
type of concern	product conditions	reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		Cosmetic Ingredient Review Assessments
262 studies in PubMed science library may include information on the toxicity of this chemical see search results ->		PubMed

Ecotoxicology
type of concern	product conditions	reference
Not suspected to be an environmental toxin		Environment Canada Domestic Substance List

Persistence and bioaccumulation

type of concern

product conditions

reference

Not suspected to be persistent

Environment Canada Domestic Substance List

Organ system toxicity (non-reproductive)
type of concern	product conditions	reference
Classified as not expected to be potentially toxic or harmful		Environment Canada Domestic Substance List

Government, industry, academic studies and classifications
government/industry list/academic study	appears on list as	classification(s)
Cosmetic Ingredient Review Assessments	PANTHENOL	QQQ01,QQQ11; D_
FDA Everything Added to Food	D-PANTOTHENYL ALCOHOL	• NUL
Environment Canada Domestic Substance List	BUTANAMIDE, 2,4-DIHYDROXY-N-(3-HYDROXYPROPYL)-3,3-DIMETHYL-, (±)-	,,,,,,,,,
IFRA Fragrance Ingredient List	BUTANAMIDE, 2,4-DIHYDROXY-N-(3-HYDROXYPROPYL)-3,3-DIMETHYL-	reported as used in fragrance compounds in 2008

Other RTECS® classifications [shown for informational purposes only]
government/industry list/academic study	appears on list as	classification(s)
RTECS^®- Farmaco, Edizione Scientifica 1959	PANTHENOL	• broad systemic - Broad systemic toxicity (mouse LD50)

references
government/industry list/academic study	reference
Cosmetic Ingredient Review Assessments	CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
FDA Everything Added to Food	FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
Environment Canada Domestic Substance List	EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
IFRA Fragrance Ingredient List	IFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25
RTECS^®- Farmaco, Edizione Scientifica 1959 [shown for informational purposes only]	RTECS^®- Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 14,43,1959