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METHYL SALICYLATE


image source: PubChem
Health Concerns of the Ingredient:
Overall Hazard
 
 
Cancer
 
 
 
Allergies & immunotoxicity
 
 

About METHYL SALICYLATE: Methyl salicylate is an anti-inflammatory ingredient common in pain relief creams for muscles and joints. Although the U.S. cosmetic industry's safety panel (Cosmetic Ingredient Review) considers this ... read more

Function(s): Denaturant; External Analgesic; Flavoring Agent; Fragrance Ingredient; PERFUMING; SOOTHING

Synoym(s): 2-CARBOMETHOXYPHENOL; 2-HYDROXY- METHYL ESTER BENZOIC ACID; 2-HYDROXYBENZOIC ACID, METHYL ESTER; BENZOIC ACID, 2-HYDROXY-, METHYL ESTER; BENZOIC ACID, 2HYDROXY, METHYL ESTER; BIRCH OIL, SWEET; METHYL 2-HYDROXYBENZOATE; METHYL ESTER 2-HYDROXYBENZOIC ACID; METHYL ESTER BENZOIC ACID, 2-HYDROXY-; METHYL ESTER SALICY LIC ACID; OIL (BETULA LENTA L.) BIRCH, SWEET

Use restrictions

Concern Reference
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmeticsCanada - Prohibited and Restricted Cosmetics Ingredients
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualificationsCosmetic Ingredient Review Assessments

Developmental/reproductive toxicity

Concern Reference
Limited evidence of reproductive toxicityChapin, R

Ecotoxicology

Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Data gaps

Concern Reference
2,466 studies in PubMed science library may include information on the toxicity of this chemical see search results ->NLM PubMed

Organ system toxicity (non-reproductive)

Concern Reference
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

Concern Reference
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Multiple, additive exposure sources

Concern Reference
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Data Sources

AOEC (Association of Occupational and Environmental Clinics). 2009. AEOC exposures codes and asthmagen designation.
CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
Chapin, R.E. and R.A. Sloane. NIEHS/NTP Reproductive Assessment by Continuous Breeding: Evolving Study Design and Summaries of Ninety Studies. Environmental Health Perspectives 105, Supplement 1: 199-394. 1997. http://ehpnet1.niehs.nih.gov/docs/1997/Suppl-1/chapin.html
EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
Health Canada. 2007. List of Prohibited and Restricted Cosmetic Ingredients. Canada's Cosmetic Ingredient Hotlist. March 2007.
IFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25
NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

About the ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer