ISOPROPYL PALMITATE
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About the ratings
EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any.
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Function/use(s): Binder; Fragrance Ingredient; Skin-Conditioning Agent - Emollient; ANTISTATIC; BINDING; PERFUMING; SKIN CONDITIONING; SOLVENT
About ISOPROPYL PALMITATE: Isopropyl Palmitate is an ester of isopropyl alcohol and palmitic acid.
Synonym(s): ISOPROPYL PALMITATE ISOPROPYL PALMITATE, HEXADECANOIC ACID, 1-METHYLETHYL ESTER; IPP; ISOPROPYL N-HEXADECANOATE; 1-METHYLETHYL HEXADECANOATE; PALMITIC ACID, ISOPROPYL ESTER; 1-METHYLETHYL ESTER HEXADECANOIC ACID; ISOPROPYL ESTER PALMITIC ACID; HEXADECANOIC ACID, 1METHYLETHYL ESTER; CRODAMOL IPP; DELTYL; DELTYL PRIME
This ingredient may be derived from animals. From PETA's Caring Consumer: Complex mixtures of isomers of stearic acid and palmitic acid. (See Stearic Acid.)
Data gaps |
| type of concern |
product conditions |
reference |
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| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product |
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Cosmetic Ingredient Review Assessments |
| 1,004 studies in PubMed science library may include information on the toxicity of this chemical
see search results ->
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PubMed |
Ecotoxicology |
| type of concern |
product conditions |
reference |
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| Not suspected to be an environmental toxin |
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Environment Canada Domestic Substance List |
Multiple, additive exposure sources |
| type of concern |
product conditions |
reference |
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| Designated as safe for general or specific, limited use in food |
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FDA Everything Added to Food |
Organ system toxicity (non-reproductive) |
| type of concern |
product conditions |
reference |
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| Classified as not expected to be potentially toxic or harmful |
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Environment Canada Domestic Substance List |
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| Classified as a low human health priority |
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Environment Canada Domestic Substance List | |
Persistence and bioaccumulation |
| type of concern |
product conditions |
reference |
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| Not suspected to be persistent |
|
Environment Canada Domestic Substance List |
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| Not suspected to be bioaccumulative |
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Environment Canada Domestic Substance List | |
Government, industry, academic studies and classifications |
| government/industry list/academic study |
appears on list as |
classification(s) |
| Cosmetic Ingredient Review Assessments | ISOPROPYL PALMITATE | QQQ01,QQQ11 |
| FDA Everything Added to Food | ISOPROPYL PALMITATE | • ASP |
| Environment Canada Domestic Substance List | HEXADECANOIC ACID, 1-METHYLETHYL ESTER | ,,Low-Health Priority,,,,,,, |
| IFRA Fragrance Ingredient List | ISOPROPYL PALMITATE | reported as used in fragrance compounds in 2008 |
Other RTECS® classifications [shown for informational purposes only] |
| government/industry list/academic study |
appears on list as |
classification(s) |
| RTECS®- "Cutaneous Toxicity, Proceedings of the 3rd Conference, 1976," Drill, V 1977 | ISOPROPYL PALMITATE | • skin - Primary skin irritant ( human )
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| RTECS®- Food and Chemical Toxicology 1982 | ISOPROPYL PALMITATE | • skin - Primary skin irritant (rabbit )
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| RTECS®- Food and Chemical Toxicology 1982 | ISOPROPYL PALMITATE | • skin - Primary skin irritant (rabbit )
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| RTECS®- National Technical Information Service | ISOPROPYL PALMITATE | • broad systemic - Broad systemic toxicity (mouse LD50)
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references |
| government/industry list/academic study
| reference
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| Cosmetic Ingredient Review Assessments | CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC. |
| FDA Everything Added to Food | FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition. |
| Environment Canada Domestic Substance List | EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry. |
| IFRA Fragrance Ingredient List | IFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25 |
| RTECS®- "Cutaneous Toxicity, Proceedings of the 3rd Conference, 1976," Drill, V 1977 [shown for informational purposes only] | RTECS®- "Cutaneous Toxicity, Proceedings of the 3rd Conference, 1976," Drill, V.A., and P. Lazar, eds., New York, Academic Press, Inc. 1977 -,127,1977 |
| RTECS®- Food and Chemical Toxicology 1982 [shown for informational purposes only] | RTECS®- Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 20,727,1982 |
| RTECS®- Food and Chemical Toxicology 1982 [shown for informational purposes only] | RTECS®- Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- 20,727,1982 |
| RTECS®- National Technical Information Service [shown for informational purposes only] | RTECS®- National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. AD277-689 |
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