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GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE

Health Concerns of the Ingredient:
Overall Hazard
 
 
Cancer
 
 
Developmental &
reproductive toxicity
 
 
Allergies & immunotoxicity
 
 
Use restrictions
 
 
Other MODERATE concerns: Organ system toxicity (non-reproductive); Other LOW concerns: Data gaps

About GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE: Guar Hydroxypropyltrimonium Chloride is a quaternary ammonium derivative of guar gum; used in hair conditioning products.

Function(s): Antistatic Agent; Hair Conditioning Agent; Viscosity Increasing Agent - Aqueous; FILM FORMING; SKIN CONDITIONING; VISCOSITY CONTROLLING

Synoym(s): 2-HYDROXY-3- (TRIMETHYLAMMONIO) PROPYL ETHER CHLORIDE GUAR GUM; CHLORIDE GUAR GUM, 2-HYDROXY-3- (TRIMETHYLAMMONIO) PROPYL ETHER; GUAR GUM, 2-HYDROXY-3- (TRIMETHYLAMMONIO) PROPYL ETHER, CHLORIDE; GUAR GUM, 2HYDROXY3 (TRIMETHYLAMMONIO) PROPYL ETHER, CHLORIDE; GUAR GUM, ETHER WITH 3-CHLORO-2-HYDROXYPROPYLTRIMETHYLAMMONIUM CHLORIDE; GUAR, 2-HYDROXY-3-TRIMETHYLAMMONIOPROPYL ETHER, CHLORIDE; GUAR HYDROPROPYLTRIMONIUM CHLORIDE; O- [2-HYDROXY-3- (TRIMETHYLAMMONIO) PROPYL] GUAR GUM CHLORIDE; COSMEDIA GUAR C 261; JAGUAR C 13S; JAGUAR C 14S; JAGUAR C 15

Organ system toxicity (non-reproductive)

Concern Reference
Classified as medium human health priorityEnvironment Canada Domestic Substance List
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Data gaps

Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
3 studies in PubMed science library may include information on the toxicity of this chemical see search results ->NLM PubMed

Ecotoxicology

Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Data Sources

CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

About the ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer