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GUAIAZULENE


image source: PubChem
Health Concerns of the Ingredient:
Overall Hazard
 
 
Cancer
 
 
Developmental &
reproductive toxicity
 
 
Allergies & immunotoxicity
 
 

About GUAIAZULENE: Guaiazulene is a color additive.

Function(s): Colorant; Fragrance Ingredient; ANTIMICROBIAL; PERFUMING

Synoym(s): 1,4-DIMETHYL-7- (1-METHYLETHYL) - AZULENE; 1,4-DIMETHYL-7- (1-METHYLETHYL) AZULENE; 1,4-DIMETHYL-7-ISOPROPYL-AZULENE; 7-ISOPROPYL-1,4-DIMETHYLAZULENE; AZULENE, 1,4-DIMETHYL-7- (1-METHYLETHYL) -; AZULENE, 1,4DIMETHYL7 (1METHYLETHYL) ; 1,4-DIMETHYL-7-ISOPROPYLAZULENE; AZULEN-BERIS; AZULENE, 1,4-DIMETHYL-7- (1-METHYLETHYL) -; AZULON; AZUNOL

Use restrictions

Concern Reference
Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Color additive not approved by FDA for cosmetics used around eyes (only for products for use around the eyes)FDA Color Additive Status
Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - (only for products for use on the lips)FDA

Organ system toxicity (non-reproductive)

Concern Reference
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List

Ecotoxicology

Concern Reference
Suspected to be an environmental toxin and be persistent or bioaccumulativeEnvironment Canada Domestic Substance List
Suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Data gaps

Concern Reference
93 studies in PubMed science library may include information on the toxicity of this chemical see search results ->NLM PubMed

Persistence and bioaccumulation

Concern Reference
Not suspected to be persistentEnvironment Canada Domestic Substance List

Data Sources

CTFA (Cosmetic, Toiletry and Fragrance Association). 2006. International Cosmetic Ingredient Dictionary and Handbook, 11th Edition. Color Additive Information. Washington, DC.
EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
FDA (U.S. Food and Drug Administration) 2006. Center for Food Safety and Applied Nutrition. Color Additive Status List. September 2006.
FDA. 2010. Color Additives Permitted for Use in Cosmetics: Table. April 30, 2008; Updated June 20, 2008 and February 22, 2010. http://www.fda.gov/cosmetics/guidancecomplianceregulatoryinformation/voluntarycosmeticsregistrationprogramvcrp/onlineregistration/ucm109084.htm
IFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25
NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

About the ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer