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GLYCINE
Score
Data: Fair
CAS56-40-6
conditioner (64 products)
shampoo (59 products)
facial moisturizer/ treatment (53 products)
moisturizer (49 products)
anti-aging (45 products)
Show all 314 products that contain GLYCINE.
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GLYCINE


image source: PubChem
Health concerns of ingredient
About the ratings
Cancer no information
Developmental & reproductive toxicity no information
Allergies & immunotoxicity no information
Use restrictions no information
Contamination concerns: none
Other LOW concerns: Data gaps

About the ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

Function/use(s): Buffering Agent; Fragrance Ingredient; Hair Conditioning Agent; Skin-Conditioning Agent -Miscellaneous; ANTISTATIC; SKIN CONDITIONING

About GLYCINE: Glycine is a naturally occurring amino acid.

Synonym(s): AMINOACETIC ACID; AMINOETHANOIC ACID; GLYCOCOLL; 2-AMINOACETIC ACID; ACIPORT; AMINOACETIC ACID; AMINOETHANOIC ACID; GLICOAMIN; GLYCOCOLL; GLYCOLIXIR; GLYCOSTHENE

Data gaps

type of concern product conditions reference
Not assessed for safety in cosmetics by industry panel  
57,331 studies in PubMed science library may include information on the toxicity of this chemical see search results ->   PubMed

Ecotoxicology

type of concern product conditions reference
Not suspected to be an environmental toxin    Environment Canada Domestic Substance List

Multiple, additive exposure sources

type of concern product conditions reference
Designated as safe for general or specific, limited use in food   FDA Everything Added to Food
Designated as safe for general or specific, limited use in food   FDA Food Additive Status

Organ system toxicity (non-reproductive)

type of concern product conditions reference
Classified as not expected to be potentially toxic or harmful    Environment Canada Domestic Substance List

Persistence and bioaccumulation

type of concern product conditions reference
Not suspected to be bioaccumulative    Environment Canada Domestic Substance List
show more

Government, industry, academic studies and classifications
government/industry list/academic study appears on list as classification(s)
FDA Food Additive StatusGLYCINE• MISC
• REG
• 0.2% of fin bev or bev base Masking agent for saccharin in beverages & bases -172.812
• STAB
• 0.02% - In mono- and diglycerides -172.812
• NUTR - CFR172.320
FDA Everything Added to FoodGLYCINE• ASP
Environment Canada Domestic Substance ListGLYCINE,,,,,,,,,

Other RTECS® classifications [shown for informational purposes only]
government/industry list/academic study appears on list as classification(s)
RTECS®- Eksperimental'naya i Klinicheskaya Farmakologiya 1993GLYCINE• brain, nervous system, or behavioral effect - Alteration of operant conditioning (rat TDLo)
RTECS®- Journal of Pharmacology and Experimental Therapeutics 2001GLYCINE• metabolic - Weight loss or decreased weight gain (rat TDLo)
• biochemical - Xanthine, purine, or nucleotides, including urate (rat TDLo)
• liver - Other changes (rat TDLo)
RTECS®- Mutation Research 1992GLYCINE• mutagenic - Positive mutation assay: Sister Chromatid Exchange ( human lym)
RTECS®- Mutation Research 1992GLYCINE• mutagenic - Positive mutation assay: Sister Chromatid Exchange ( human lym)
RTECS®- Neuropsychopharmacology 2001GLYCINE• brain, nervous system, or behavioral effect - Changes in motor activity (specific assay) (rat TDLo)
RTECS®- Neuropsychopharmacology 2004GLYCINE• cancer - biochemical Protects against induction of experimental tumors (rat TDLo)
• biochemical - Dopamine in striatum (rat TDLo)
RTECS®- Toxicologist 2003GLYCINE
RTECS®- Yakuri to Chiryo 1977GLYCINE• broad systemic - Broad systemic toxicity (mouse LD50)
• blood - Changes in leucocyte (WBC) count (rat TDLo)
• endocrine system - Changes in spleen weight (rat TDLo)
• respiratory - Respiratory depression (rat TDLo)

references
government/industry list/academic study reference
FDA Food Additive StatusFDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
FDA Everything Added to FoodFDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
Environment Canada Domestic Substance ListEC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
RTECS®- Eksperimental'naya i Klinicheskaya Farmakologiya 1993 [shown for informational purposes only]RTECS®- Eksperimental'naya i Klinicheskaya Farmakologiya. Experimental and Clinical Pharmacology. (Mezhdunarodnaya Kniga, ul. B. Yakimanka, 39, 117049 Moscow, Russia) V.55- 1992- 56,55,1993
RTECS®- Journal of Pharmacology and Experimental Therapeutics 2001 [shown for informational purposes only]RTECS®- Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- 299,858,2001
RTECS®- Mutation Research 1992 [shown for informational purposes only]RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 280,279,1992
RTECS®- Mutation Research 1992 [shown for informational purposes only]RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- -1964 280,279,1992
RTECS®- Neuropsychopharmacology 2001 [shown for informational purposes only]RTECS®- Neuropsychopharmacology. (Elsevier Science, 655 Avenue of the Americas, New York, NY 10010) V.1- 1987- 24,330,2001
RTECS®- Neuropsychopharmacology 2004 [shown for informational purposes only]RTECS®- Neuropsychopharmacology. (Elsevier Science, 655 Avenue of the Americas, New York, NY 10010) V.1- 1987- 29,300,2004
RTECS®- Toxicologist 2003 [shown for informational purposes only]RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- -1981 72,212,2003
RTECS®- Yakuri to Chiryo 1977 [shown for informational purposes only]RTECS®- Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972- 5,1502,1977

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