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Score
Data: Fair
CAS56-81-5
moisturizer (1,712 products)
facial moisturizer/ treatment (1,615 products)
anti-aging (1,041 products)
facial cleanser (923 products)
body wash/ cleanser (791 products)
Show all 10,034 products that contain GLYCERIN.
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GLYCERIN


image source: PubChem
Health concerns of ingredient
About the ratings
Cancer no information
Developmental & reproductive toxicity no information
Allergies & immunotoxicity no information
Use restrictions no information
Contamination concerns: none
Other LOW concerns: Data gaps

About the ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

Function/use(s): Denaturant; Fragrance Ingredient; Hair Conditioning Agent; Humectant; Oral Care Agent;Oral Health Care Drug; Skin-Conditioning Agent - Humectant; Skin Protectant; Viscosity Decreasing Agent; PERFUMING; SOLVENT

About GLYCERIN: Glycerin (also called glycerol) is a naturally occurring alcohol compound and a component of many lipids. Glycerin may be of animal or vegetable origin. This ingredient is listed in the PETA's Caring ... read more

Synonym(s): CONCENTRATED GLYCERIN; GLYCERINE; GLYCEROL; GLYCYL ALCOHOL; 1,2,3-PROPANETRIOL; 1,2,3-TRIHYDROXYPROPANE; VEGETABLE GLYCERIN; 1,2,3PROPANETRIOL; 1,2,3-PROPANETRIOL; 1,2,3-TRIHYDROXYPROPANE; 90 TECHNICAL GLYCERINE

This ingredient may be derived from animals. From PETA's Caring Consumer: A byproduct of soap manufacture (normally uses animal fat). In cosmetics, foods, mouthwashes, chewing gum, toothpastes, soaps, ointments, medicines, lubricants, transmission and brake fluid, and plast ... read more

Data gaps

type of concern product conditions reference
Not assessed for safety in cosmetics by industry panel  
56,768 studies in PubMed science library may include information on the toxicity of this chemical see search results ->   PubMed

Ecotoxicology

type of concern product conditions reference
Not suspected to be an environmental toxin    Environment Canada Domestic Substance List

Multiple, additive exposure sources

type of concern product conditions reference
Designated as safe for general or specific, limited use in food   FDA Food Additive Status
Designated as safe for general or specific, limited use in food   FDA Everything Added to Food

Organ system toxicity (non-reproductive)

type of concern product conditions reference
Classified as a low human health priority    Environment Canada Domestic Substance List
show more

Persistence and bioaccumulation

type of concern product conditions reference
Not suspected to be bioaccumulative    Environment Canada Domestic Substance List
show more

Government, industry, academic studies and classifications

government/industry list/academic study appears on list as classification(s)
FDA Food Additive StatusGLYCERIN• MISC
• GRAS/FS
• GMP
• Part 169
• Food Flavorings
• 182.1320
• Part 582 - Animal feeds
FDA Food Additive StatusGLYCEROL• See glycerin
FDA Everything Added to FoodGLYCERIN• ASP
Environment Canada Domestic Substance List1,2,3-PROPANETRIOL,,Low-Health Priority,,,,,,,
IFRA Fragrance Ingredient ListGLYCEROLreported as used in fragrance compounds in 2008
National Library of Medicine HazMapGLYCERIN MISTSD: No;TL: 10 ppm;FL: 1: must be preheated;

Other RTECS® classifications [shown for informational purposes only]

government/industry list/academic study appears on list as classification(s)
RTECS®- TLV/BEI,2005GLYCERIN• occupationally related - ACGIH TLV (human TWA)
RTECS®- TLV/BEI,2006GLYCERIN• occupationally related - ACGIH TLV (human TWA)
RTECS®- TLV/BEI,2007GLYCERIN• occupationally related - ACGIH TLV (human TWA)
RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J 1986GLYCERIN• sense organ - Primary eye irritant (rabbit )
• skin - Primary skin irritant (rabbit )
RTECS®- "Toxicology of Drugs and Chemicals," Deichmann, W 1969GLYCERIN• brain, nervous system, or behavioral effect - Headache ( human TDLo)
• gastrointestinal - Nausea or vomiting ( human TDLo)
RTECS®- Arzneimittel-Forschung 1976GLYCERIN• broad systemic - Broad systemic toxicity (rat LD50)
RTECS®- Arzneimittel-Forschung 1978GLYCERIN• brain, nervous system, or behavioral effect - Altered sleep time (including change in righting reflex) (mouse LD50)
RTECS®- BIOFAX Industrial Bio-Test Laboratories, Inc 1970GLYCERIN• endocrine system - Changes in adrenal weight (rat TDLo)
• sense organ - Primary eye irritant (rabbit )
RTECS®- Cancer Letters (Shannon, Ireland) 2000GLYCERIN• cancer - Facilitates action of known carcinogen (mouse TDLo)
• skin - Tumors (mouse TDLo)
RTECS®- Cancer Letters (Shannon, Ireland) 2005GLYCERIN• cancer - Facilitates action of known carcinogen (mouse TDLo)
• cancer - respiratory tumor formations - equivocal (mouse TDLo)
RTECS®- Contraception 1984GLYCERIN• reproductive - Male fertility index (rat TDLo)
• reproductive - Spermatogenesis (rat TDLo)
• reproductive - Testes, epididymis, sperm duct (rat TDLo)
RTECS®- Contraception 1989GLYCERIN• reproductive - Spermatogenesis (monkey TDLo)
• reproductive - Testes, epididymis, sperm duct (monkey TDLo)
RTECS®- Delaware State Medical Journal 1959GLYCERIN• broad systemic - Broad systemic toxicity (rabbit LD50)
RTECS®- Drugs in Japan (Ethical Drugs) 1982GLYCERIN• broad systemic - Broad systemic toxicity (mouse LD50)
RTECS®- Eksperimental'naya i Klinicheskaya Farmakologiya 1992GLYCERIN• kidney or renal system - Renal function tests depressed (rat TDLo)
RTECS®- Experimental Lung Research 1987GLYCERIN• respiratory - Structural or functional change in trachea or bronchi (mouse TDLo)
RTECS®- Farmatsevtichnii Zhurnal (Kiev) 1977GLYCERIN• broad systemic - Broad systemic toxicity (mouse LD50)
RTECS®- Federation Proceedings, Federation of American Societies for Experimental Biology 1945GLYCERIN• brain, nervous system, or behavioral effect - General anesthetic (rat LD50)
• brain, nervous system, or behavioral effect - Muscle weakness (rat LD50)
• liver - Other changes (rat LD50)
RTECS®- Gigiena i Sanitariya 1984GLYCERIN• biochemical - True cholinesterase (rat TDLo)
• blood - Changes in leucocyte (WBC) count (rat TDLo)
• blood - Changes in serum composition (eg., TP, bilirubin, cholesterol) (rat TDLo)
RTECS®- Journal of Industrial Hygiene and Toxicology 1941GLYCERIN• broad systemic - Broad systemic toxicity (guinea pig LD50)
RTECS®- Journal of the American Pharmaceutical Association, Scientific Edition 1950GLYCERIN• broad systemic - Broad systemic toxicity (mouse LD50)
RTECS®- Life Sciences 1984GLYCERIN• reproductive - Spermatogenesis (rat TDLo)
RTECS®- Nephron 1978GLYCERIN• kidney or renal system - Changes in tubules (including acute renal failure, acute tubular (rat LDLo)
• kidney or renal system - Other changes in urine composition (rat LDLo)
RTECS®- Proceedings of the National Academy of Sciences of the United States of America 1982GLYCERIN• mutagenic - Positive mutation assay: DNA Inhibition ( human lym)
RTECS®- Proceedings of the National Academy of Sciences of the United States of America 1982GLYCERIN• mutagenic - Positive mutation assay: DNA Inhibition ( human lym)
RTECS®- Research Communications in Chemical Pathology and Pharmacology 1987GLYCERIN• cardiovascular - Other changes (rat LD50)
• brain, nervous system, or behavioral effect - Toxic psychosis (rat LD50)
RTECS®- Tsitologiya i Genetika 1985GLYCERIN• reproductive - Post-implantation mortality (rat TDLo)
• mutagenic - Positive mutation assay: Cytogenetic Analysis (rat orl)
RTECS®- Tsitologiya i Genetika 1985GLYCERIN• mutagenic - Positive mutation assay: Cytogenetic Analysis (rat orl)

references

government/industry list/academic study reference
FDA Food Additive StatusFDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
FDA Everything Added to FoodFDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
Environment Canada Domestic Substance ListEC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
IFRA Fragrance Ingredient ListIFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25
National Library of Medicine HazMapNLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
RTECS®- TLV/BEI,2005 [shown for informational purposes only]RTECS®- TLV/BEI,2005
RTECS®- TLV/BEI,2006 [shown for informational purposes only]RTECS®- TLV/BEI,2006
RTECS®- TLV/BEI,2007 [shown for informational purposes only]RTECS®- TLV/BEI,2007
RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J 1986 [shown for informational purposes only]RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 -,207,1986
RTECS®- "Toxicology of Drugs and Chemicals," Deichmann, W 1969 [shown for informational purposes only]RTECS®- "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969 -,288,1969
RTECS®- Arzneimittel-Forschung 1976 [shown for informational purposes only]RTECS®- Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- 26,1581,1976
RTECS®- Arzneimittel-Forschung 1978 [shown for informational purposes only]RTECS®- Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- 28,1579,1978
RTECS®- BIOFAX Industrial Bio-Test Laboratories, Inc 1970 [shown for informational purposes only]RTECS®- BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. (1810 Frontage Rd., Northbrook, IL 60062) 9-4/1970
RTECS®- Cancer Letters (Shannon, Ireland) 2000 [shown for informational purposes only]RTECS®- Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- 155,61,2000
RTECS®- Cancer Letters (Shannon, Ireland) 2005 [shown for informational purposes only]RTECS®- Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- 229,181,2005
RTECS®- Contraception 1984 [shown for informational purposes only]RTECS®- Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- 29,291,1984
RTECS®- Contraception 1989 [shown for informational purposes only]RTECS®- Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- 39,447,1989
RTECS®- Delaware State Medical Journal 1959 [shown for informational purposes only]RTECS®- Delaware State Medical Journal. (Wilmington, DE) V.1-32(1), 1929-60. For publisher information, see DSMJAA. 31,276,1959
RTECS®- Drugs in Japan (Ethical Drugs) 1982 [shown for informational purposes only]RTECS®- Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) 6,215,1982
RTECS®- Eksperimental'naya i Klinicheskaya Farmakologiya 1992 [shown for informational purposes only]RTECS®- Eksperimental'naya i Klinicheskaya Farmakologiya. Experimental and Clinical Pharmacology. (Mezhdunarodnaya Kniga, ul. B. Yakimanka, 39, 117049 Moscow, Russia) V.55- 1992- 55,21,1992
RTECS®- Experimental Lung Research 1987 [shown for informational purposes only]RTECS®- Experimental Lung Research. (Hemisphere Publishing, c/o Taylor & Francis 1900 Frost Road, Suite 101, Bristol, PA 19007) V.1- 1980- 12,281,1987
RTECS®- Farmatsevtichnii Zhurnal (Kiev) 1977 [shown for informational purposes only]RTECS®- Farmatsevtichnii Zhurnal (Kiev). (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.3- -1930 (6),56,1977
RTECS®- Federation Proceedings, Federation of American Societies for Experimental Biology 1945 [shown for informational purposes only]RTECS®- Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. 4,142,1945
RTECS®- Gigiena i Sanitariya 1984 [shown for informational purposes only]RTECS®- Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- 49(10),81,1984
RTECS®- Journal of Industrial Hygiene and Toxicology 1941 [shown for informational purposes only]RTECS®- Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. 23,259,1941
RTECS®- Journal of the American Pharmaceutical Association, Scientific Edition 1950 [shown for informational purposes only]RTECS®- Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. 39,583,1950
RTECS®- Life Sciences 1984 [shown for informational purposes only]RTECS®- Life Sciences. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1-8, 1962-69; V.14- 1974- 34,1747,1984
RTECS®- Nephron 1978 [shown for informational purposes only]RTECS®- Nephron. (S. Karger Pub., Inc., 79 Fifth Ave., New York, NY 10003) V.1- 1964- 20,47,1978
RTECS®- Proceedings of the National Academy of Sciences of the United States of America 1982 [shown for informational purposes only]RTECS®- Proceedings of the National Academy of Sciences of the United States of America. (National Academy of Sciences, Printing & Pub. Office, 2101 Constitution Ave., Washington, DC 20418) V.1- 1915- 79,1171,1982
RTECS®- Proceedings of the National Academy of Sciences of the United States of America 1982 [shown for informational purposes only]RTECS®- Proceedings of the National Academy of Sciences of the United States of America. (National Academy of Sciences, Printing & Pub. Office, 2101 Constitution Ave., Washington, DC 20418) V.1- 79,1171,1982
RTECS®- Research Communications in Chemical Pathology and Pharmacology 1987 [shown for informational purposes only]RTECS®- Research Communications in Chemical Pathology and Pharmacology. (PJD Pub. Ltd., P.O. Box 966, Westbury, NY 11590) V.1- 1970- 56,125,1987
RTECS®- Tsitologiya i Genetika 1985 [shown for informational purposes only]RTECS®- Tsitologiya i Genetika. Cytology and Genetics. For English translation, see CYGEDX. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1967- 19,436,1985
RTECS®- Tsitologiya i Genetika 1985 [shown for informational purposes only]RTECS®- Tsitologiya i Genetika. Cytology and Genetics. For English translation, see CYGEDX. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 19,436,1985

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