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Data: Fair

Fd&C Red No. 4 (Ci 14700)

IMAGE SOURCE: PubChem

SEARCH PRODUCTS

Other Concerns

Use restrictions (high) and Endocrine disruption (low)

SYNONYMS

● 1-NAPHTHALENESULFONIC ACID, 3-[(2,4-DIMETHYL-5-SULFOPHENYL)AZO]-4-HYDROXY-, DISODIUM SALT
● 1NAPHTHALENESULFONIC ACID, 3[(2,4DIMETHYL5SULFOPHENYL)AZO]4HYDROXY, DISODIUM SALT
● 3-[(2,4-DIMETHYL-5-SULFOPHENYL)AZO]-4-HYDROXY- DISODIUM SALT 1-NAPHTHALENESULFONIC ACID
● 3-[(2,4-DIMETHYL-5-SULFOPHENYL)AZO]-4-HYDROXY-1-NAPHTHALENESULFONIC ACID, DISODIUM SALT
● AKA504
● CI 14700
● D&C RED 4
● DISODIUM 3-[(2,4-DIMETHYL-5-SULPHONATOPHENYL)AZO]-4-HYDROXYNAPHTHALENE-1-SULPHONATE
● DISODIUM SALT 1-NAPHTHALENESULFONIC ACID, 3-[(2,4-DIMETHYL-5-SULFOPHENYL)AZO]-4-HYDROXY-
● DISODIUM SALT 3-[(2,4-DIMETHYL-5-SULFOPHENYL)AZO]-4-HYDROXY-1-NAPHTHALENESULFONIC ACID
● FD&C RED 4
● FD&C RED NO. 4
● FD&C RED NO. 4 (CI 14700)
● FOOD RED 1
● RED 4
● RED 504
● RED NO. 504

Unacceptable

Unacceptable: EWG VERIFIED products cannot contain this ingredient


FD&C Red 4 is a synthetic dye produced from petroleum; this dye is FDA-approved for use in food, pharmaceuticals and cosmetics.

Common concerns

See how this product scores for common concerns.

  • LOW
    Cancer
  • LOW
    Allergies & Immunotoxicity
  • LOW
    Developmental and Reproductive Toxicity
  • HIGH
    Use Restrictions

Ingredient concerns

  • CONCERNS
  • DATA SOURCES

Products with this Ingredient

Expand content Collapse content
fragrance for women88 products
liquid hand soap84 products
body wash/cleanser61 products
bath oil/salts/soak57 products
exfoliant/scrub53 products
shampoo47 products
facial moisturizer/treatment37 products
moisturizer31 products
sunless tanning29 products
body spray28 products
bar soap28 products
conditioner23 products
mask20 products
hair treatment/serum16 products
fragrance for men13 products
facial cleanser10 products
serums & essences8 products
hand sanitizer8 products
bubble bath8 products
setting powder/spray7 products
lipstick6 products
hair color and bleaching6 products
styling gel/lotion6 products
hair styling aide6 products
hand cream6 products
daily use with SPF5 products
blush5 products
toners/astringents4 products
around-eye cream3 products
antiperspirant/deodorant3 products
foot moisturizer3 products
lip balm2 products
shaving cream2 products
makeup primer2 products
nail polish2 products
after shave2 products
antiperspirant/deodorant (men's)2 products
cuticle treatment2 products
body firming lotion2 products
styling mousse/foam1 products
recreational sunscreen1 products
anti-aging1 products
1 products
mouthwash1 products
nail treatment1 products

Use restrictions

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CONCERN REFERENCE
Violation of government restrictions - Banned or found unsafe for use in cosmeticsCTFA International Cosmetic Ingredient Dictionary and Handbook
Violation of government restrictions - Banned or found unsafe for use in cosmeticsCosIng
Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Color additive approved by FDA for use in cosmetics: external use onlyFDA Color Additive Status
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - anyCosIng

Cancer

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CONCERN REFERENCE
One or more in vitro tests on mammalian cells show positive mutation resultsOpen scientific literature
Not likely to be mutagenic in humansOpen scientific literature
Not likely to be carcinogenic in humansOpen scientific literature
Limited or incomplete evidence of cancer according to safety/hazard data – government assessment cannot classify as human carcinogen due to data gapsInt'l Agency for Research on Cancer (IARC) - Carcinogens

Endocrine disruption

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CONCERN REFERENCE
Associated with endocrine disruptionOpen scientific literature

Data gaps

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CONCERN REFERENCE
74 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Ecotoxicology

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CONCERN REFERENCE
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Informational

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CONCERN REFERENCE
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color Additives - Batch Certified by the U.S. Food and Drug AdministrationCTFA International Cosmetic Ingredient Dictionary and Handbook
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - The substance was formerly approved as a food additive but is now banned; there may be some toxicology data available.FDA Everything Added to Food
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color additive approved by FDA for use in cosmetics: external use onlyFDA Color Additive Status

Persistence and bioaccumulation

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CONCERN REFERENCE
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List
Not suspected to be persistentEnvironment Canada Domestic Substance List

Organ system toxicity (non-reproductive)

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CONCERN REFERENCE
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List
  • CTFA (Cosmetic, Toiletry and Fragrance Association). 2006. International Cosmetic Ingredient Dictionary and Handbook, 11th Edition. Color Additive Information. Washington, DC.
  • European Commission. 2013. Cosing, the European Commission database with information on cosmetic substances and ingredients. Accessed on March 1, 2013 at http://ec.europa.eu/consumers/cosmetics/cosing/ .
  • FDA (U.S. Food and Drug Administration) 2006. Center for Food Safety and Applied Nutrition. Color Additive Status List. September 2006.
  • Open scientific/peer reviewed literature
  • IARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures).
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.

HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED® mark means a product meets EWG’s strictest criteria for transparency and health.

Score legend

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST
Low Availability
Moderate Availability
High Availability

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