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ETHANOLAMINE
Score
Data: Good
CAS141-43-5
hair color and bleaching (524 products)
shampoo (6 products)
hair relaxer (1 products)
Garnier Hair Color (1 products)
Show all 526 products that contain ETHANOLAMINE.
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ETHANOLAMINE


image source: PubChem
Health concerns of ingredient
About the ratings
Cancer no information
Developmental & reproductive toxicity no information
Allergies & immunotoxicityyes
Use restrictionsyes
Contamination concerns: none
Other HIGH concerns: Occupational hazards
Other MODERATE concerns: Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)

About the ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

Function/use(s): pH Adjuster; BUFFERING

About ETHANOLAMINE: Ethanolamine is a small-molecular weight, nitrogen-containing buffering agent.

Synonym(s): 2-AMINOETHANOL; ETHANOL, 2-AMINO-; 2-HYDROXYETHYLAMINE; MONOETHANOLAMINE; 2-AMINO- ETHANOL; ETHANOL, 2AMINO; MEA; 2-AMINOAETHANOL (GERMAN) ; 2-AMINOETANOLO (ITALIAN) ; 2-AMINOETHANOL (OSHA) ; 2-HYDROXYETHYLAMINE

Use restrictions

type of concern product conditions reference
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Unsafe in products left on skin and not rinsed off products that are intended to be left on the skin Cosmetic Ingredient Review Assessments
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications   Cosmetic Ingredient Review Assessments

Allergies/immunotoxicity

type of concern product conditions reference
Human skin toxicant - strong evidence    Cosmetic Ingredient Review Assessments
Human immune and respiratory toxicant - strong evidence products that may be aerosolized (airborne)  Association of Occupational and Environmental Clinics
Human immune and respiratory toxicant - strong evidence    Association of Occupational and Environmental Clinics
Human immune system toxicant - moderate evidence    National Library of Medicine HazMap

Occupational hazards

type of concern product conditions reference
Allowed workplace exposures restricted to low doses    European Union - Classification & Labelling

Organ system toxicity (non-reproductive)

type of concern product conditions reference
Classified as expected to be toxic or harmful    Environment Canada Domestic Substance List
show more

Irritation (skin, eyes, or lungs)

type of concern product conditions reference
Human skin irritant - moderate evidence    National Library of Medicine HazMap

Multiple, additive exposure sources

type of concern product conditions reference
Designated as safe for general or specific, limited use in food   FDA Food Additive Status
Designated as safe for general or specific, limited use in food   FDA Everything Added to Food

Miscellaneous

type of concern product conditions reference
Occupational hazards related to handling   European Union - Classification & Labelling

Data gaps

type of concern product conditions reference
7,513 studies in PubMed science library may include information on the toxicity of this chemical see search results ->   PubMed

Government, industry, academic studies and classifications
government/industry list/academic study appears on list as classification(s)
European Union - Classification & Labelling2-AMINOETHANOLXn; R20/21/22; C; R34
FDA Food Additive StatusMONOETHANOLAMINE• MISC
• REG
• < 0.3 ppm in flume water - Used in flume water for washing sugar beets prior to slicing operation - CFR173.315
Association of Occupational and Environmental ClinicsETHANOLAMINES, NOS• ARs
Association of Occupational and Environmental ClinicsMONOETHANOLAMINE• ARs
Association of Occupational and Environmental ClinicsMONOETHANOLAMINE• ARs
Cosmetic Ingredient Review AssessmentsETHANOLAMINEQQQ02; S, M-
Cosmetic Ingredient Review AssessmentsMONOETHANOLAMINEQQQ02,QQQ07,QQQ08; S, M-
FDA Everything Added to FoodMONOETHANOLAMINE• ASP
Environment Canada Domestic Substance ListETHANOL, 2-AMINO-Y-Categorization,Y-Human health,Moderate-Health Priority,,,,,,,
National Library of Medicine HazMapETHANOLAMINEAS: Yes;SD: No;DE: Skin Burns;HE: Hepatotoxin, Secondary;PE: 3 ppm;ST: 6 ppm;LC: 291 ppm;TL: 3 ppm;FL: 2: high ambient temperature required;ID: 30 ppm;OH: 4 ppm;OL: 2 ppm;MA: 2 ppm;

Other RTECS® classifications [shown for informational purposes only]
government/industry list/academic study appears on list as classification(s)
RTECS®- TLV/BEI,2006ETHANOLAMINE• occupationally related - ACGIH TLV (human TWA)
RTECS®- TLV/BEI,2007ETHANOLAMINE• occupationally related - ACGIH TLV (human TWA)
RTECS®- American Journal of Ophthalmology 1946ETHANOLAMINE• sense organ - Primary eye irritant (rabbit )
RTECS®- American Journal of Ophthalmology 1946ETHANOLAMINE• sense organ - Primary eye irritant (rabbit )
RTECS®- Biologicheskii Zhurnal Armenii 1986ETHANOLAMINE• mutagenic - Positive mutation assay: Cytogenetic Analysis ( human lym)
RTECS®- Biologicheskii Zhurnal Armenii 1986ETHANOLAMINE• mutagenic - Positive mutation assay: Cytogenetic Analysis ( human lym)
RTECS®- Cytology and Genetics (English Translation) 1987ETHANOLAMINE• mutagenic - Positive mutation assay: Sister Chromatid Exchange ( human lym)
RTECS®- Cytology and Genetics (English Translation) 1987ETHANOLAMINE• mutagenic - Positive mutation assay: Sister Chromatid Exchange ( human lym)
RTECS®- Fundamental and Applied Toxicology 1996ETHANOLAMINE• reproductive - Other effects (rat TDLo)
RTECS®- Fundamental and Applied Toxicology 1997ETHANOLAMINE• reproductive - Other effects (rat TDLo)
RTECS®- Gigiena i Sanitariya 1964ETHANOLAMINE• metabolic - Weight loss or decreased weight gain (rat TDLo)
• liver - Changes in liver weight (rat TDLo)
• liver - Liver function tests impaired (rat TDLo)
RTECS®- Gigiena Truda i Professional'nye Zabolevaniya 1979ETHANOLAMINE• broad systemic - Broad systemic toxicity (rabbit LD50)
RTECS®- Kosmicheskaya Biologiya i Meditsina 1968ETHANOLAMINE• respiratory - Dyspnea (rat LD50)
• brain, nervous system, or behavioral effect - Muscle contraction or spasticity (rat LD50)
• brain, nervous system, or behavioral effect - Somnolence (general depressed activity) (rat LD50)
RTECS®- MSHA STANDARD-air: 3,100,1971ETHANOLAMINE• occupationally related - MSHA STANDARD-air (human TWA)
RTECS®- National Technical Information Service 6797ETHANOLAMINE• kidney or renal system - Changes in bladder weight (rat TDLo)
• liver - Changes in liver weight (rat TDLo)
RTECS®- OSHA PEL (Construc): 29,1926 1994ETHANOLAMINE• occupationally related - OSHA PEL (Construc) (human TWA)
RTECS®- OSHA PEL (Fed Cont): 41,50-204 1994ETHANOLAMINE• occupationally related - OSHA PEL (Fed Cont) (human TWA)
RTECS®- OSHA PEL (Gen Indu): 29,1910 1994ETHANOLAMINE• occupationally related - OSHA PEL (Gen Indu) (human TWA)
RTECS®- OSHA PEL (Shipyard): 29,1915 1993ETHANOLAMINE• occupationally related - OSHA PEL (Shipyard) (human TWA)
RTECS®- Teratogenesis, Carcinogenesis, and Mutagenesis 1986ETHANOLAMINE• reproductive - Fetotoxicity (rat TDLo)
• developmental - Musculoskeletal system (rat TDLo)
• reproductive - Urogenital system (rat TDLo)
RTECS®- Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv 1962ETHANOLAMINE• respiratory - Dyspnea (mouse LD50)
• brain, nervous system, or behavioral effect - Muscle contraction or spasticity (mouse LD50)
• brain, nervous system, or behavioral effect - Somnolence (general depressed activity) (mouse LD50)
RTECS®- Toxicology and Applied Pharmacology 1977ETHANOLAMINE• broad systemic - Broad systemic toxicity (rat LD50)
RTECS®- Union Carbide Data Sheet 1972ETHANOLAMINE• skin - Primary skin irritant (rabbit )

references
government/industry list/academic study reference
European Union - Classification & LabellingCPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
FDA Food Additive StatusFDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
Association of Occupational and Environmental ClinicsAOEC (Association of Occupational and Environmental Clinics). 2009. AEOC exposures codes and asthmagen designation.
Cosmetic Ingredient Review AssessmentsCIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
FDA Everything Added to FoodFDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
Environment Canada Domestic Substance ListEC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
National Library of Medicine HazMapNLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
RTECS®- TLV/BEI,2006 [shown for informational purposes only]RTECS®- TLV/BEI,2006
RTECS®- TLV/BEI,2007 [shown for informational purposes only]RTECS®- TLV/BEI,2007
RTECS®- American Journal of Ophthalmology 1946 [shown for informational purposes only]RTECS®- American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N. Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 1918- 29,1363,1946
RTECS®- American Journal of Ophthalmology 1946 [shown for informational purposes only]RTECS®- American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N. Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 29,1363,1946
RTECS®- Biologicheskii Zhurnal Armenii 1986 [shown for informational purposes only]RTECS®- Biologicheskii Zhurnal Armenii. Biological Journal of Armenia. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.19- 39,422,1986
RTECS®- Biologicheskii Zhurnal Armenii 1986 [shown for informational purposes only]RTECS®- Biologicheskii Zhurnal Armenii. Biological Journal of Armenia. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.19- 1966- 39,422,1986
RTECS®- Cytology and Genetics (English Translation) 1987 [shown for informational purposes only]RTECS®- Cytology and Genetics (English Translation). Translation of TGANAK. (Allerton Press Inc., 150 Fifth Ave., New York, NY 10011) V.8- 1974- 21(6),29,1987
RTECS®- Cytology and Genetics (English Translation) 1987 [shown for informational purposes only]RTECS®- Cytology and Genetics (English Translation). Translation of TGANAK. (Allerton Press Inc., 150 Fifth Ave., New York, NY 10011) V.8- 21(6),29,1987
RTECS®- Fundamental and Applied Toxicology 1996 [shown for informational purposes only]RTECS®- Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1-40, 1981-97. For publisher information, see TOSCF2 31,117,1996
RTECS®- Fundamental and Applied Toxicology 1997 [shown for informational purposes only]RTECS®- Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1-40, 1981-97. For publisher information, see TOSCF2 40,158,1997
RTECS®- Gigiena i Sanitariya 1964 [shown for informational purposes only]RTECS®- Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- 29(2),9,1964
RTECS®- Gigiena Truda i Professional'nye Zabolevaniya 1979 [shown for informational purposes only]RTECS®- Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI 23(9),55,1979
RTECS®- Kosmicheskaya Biologiya i Meditsina 1968 [shown for informational purposes only]RTECS®- Kosmicheskaya Biologiya i Meditsina. Space Biology and Medicine. (Moscow, USSR) V.1-7, 1967-73. For publisher information, see KBAMAJ. (4),44,1968
RTECS®- MSHA STANDARD-air: 3,100,1971 [shown for informational purposes only]RTECS®- MSHA STANDARD-air: 3,100,1971
RTECS®- National Technical Information Service 6797 [shown for informational purposes only]RTECS®- National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. OTS0516797
RTECS®- OSHA PEL (Construc): 29,1926 1994 [shown for informational purposes only]RTECS®- OSHA PEL (Construc): 29,1926.55,1994
RTECS®- OSHA PEL (Fed Cont): 41,50-204 1994 [shown for informational purposes only]RTECS®- OSHA PEL (Fed Cont): 41,50-204.50,1994
RTECS®- OSHA PEL (Gen Indu): 29,1910 1994 [shown for informational purposes only]RTECS®- OSHA PEL (Gen Indu): 29,1910.1000,1994
RTECS®- OSHA PEL (Shipyard): 29,1915 1993 [shown for informational purposes only]RTECS®- OSHA PEL (Shipyard): 29,1915.1000,1993
RTECS®- Teratogenesis, Carcinogenesis, and Mutagenesis 1986 [shown for informational purposes only]RTECS®- Teratogenesis, Carcinogenesis, and Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1980- 6,403,1986
RTECS®- Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv 1962 [shown for informational purposes only]RTECS®- Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- 4,81,1962
RTECS®- Toxicology and Applied Pharmacology 1977 [shown for informational purposes only]RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 42,417,1977
RTECS®- Union Carbide Data Sheet 1972 [shown for informational purposes only]RTECS®- Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) 1/13/1972

"RTECS®" is a United States trademark owned and licensed under authority of the U.S. Government, by and through MDL Information Systems, Inc.