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LIMONENE
Score
Data: Fair
CAS138-86-3
facial moisturizer/ treatment (234 products)
moisturizer (206 products)
hair color and bleaching (176 products)
shampoo (143 products)
conditioner (143 products)
Show all 2,059 products that contain LIMONENE.
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LIMONENE


image source: PubChem
Health concerns of ingredient
About the ratings
Cancer no information
Developmental & reproductive toxicityyes
Allergies & immunotoxicityyes
Use restrictionsyes
Contamination concerns: none
Other HIGH concerns: Irritation (skin, eyes, or lungs)
Other LOW concerns: Ecotoxicology, Data gaps, Occupational hazards

About the ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

Function/use(s): PERFUMING

About LIMONENE: Limonene is a scent ingredient and solvent naturally ocurring in the rind of citrus fruit. Upon storage and exposure to sunlight and air, limonene degrades to various oxidation products which act as ... read more

Synonym(s): DL-LIMONENE; D,L-LIMONENE (ISOMER UNSPECIFIED) ; DL-LIMONENE (RACEMIC) ; 1-METHYL-4-ISOPROPENPYLCYCLOHEXENE; 1-METHYL-4- (1-METHYLETHENYL) CYCLOHEXENE; DIPENTENE; LIMONENE ESSENTIAL OIL; (+) -4-ISOPROPENYL-1-METHYLCYCLOHEXENE; (+) -R-LIMONENE; (-) -LIMONENE; (S) -LIMONENE

Allergies/immunotoxicity

type of concern product conditions reference
Known human immune system toxicant    National Library of Medicine HazMap
Possible human immune system toxicant    EU Banned and Restricted Fragrances
Limited evidence of immune system toxicity products for use on skin  European Union - Classification & Labelling

Use restrictions

type of concern product conditions reference
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Fragrance subject to restrictions: safe only if satisfies manufacturing specifications or purity limits, according to industry safety panel (International Fragrance Association)   International Fragrance Association Codes & Standards

Irritation (skin, eyes, or lungs)

type of concern product conditions reference
Classified as irritant    European Union - Classification & Labelling

Developmental/reproductive toxicity

type of concern product conditions reference
One or more animal studies show developmental effects at high doses    Kodama R, Okubo A,Araki E,Noda K,Ide H, Ikeda T, 1977

Ecotoxicology

type of concern product conditions reference
Wildlife and environmental toxicity    European Union - Classification & Labelling
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Data gaps

type of concern product conditions reference
Not assessed for safety in cosmetics by industry panel  
1,686 studies in PubMed science library may include information on the toxicity of this chemical see search results ->   PubMed

Miscellaneous

type of concern product conditions reference
Occupational hazards related to handling   European Union - Classification & Labelling

Persistence and bioaccumulation

type of concern product conditions reference
Not suspected to be bioaccumulative    Environment Canada Domestic Substance List
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Organ system toxicity (non-reproductive)

type of concern product conditions reference
Classified as not expected to be potentially toxic or harmful    Environment Canada Domestic Substance List
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Cancer

type of concern product conditions reference
Not likely to be carcinogenic in humans    Int'l Agency for Research on Cancer (IARC) - Carcinogens

Multiple, additive exposure sources

type of concern product conditions reference
Designated as safe for general or specific, limited use in food   FDA Everything Added to Food

Government, industry, academic studies and classifications
government/industry list/academic study appears on list as classification(s)
Int'l Agency for Research on Cancer (IARC) - CarcinogensD-LIMONENE IARC GROUP 3

Other RTECS® classifications [shown for informational purposes only]
government/industry list/academic study appears on list as classification(s)
RTECS®- Drug Design and Delivery (Chur Harwood Academic) V 1990LIMONENE• skin - Primary skin irritant (rabbit )
RTECS®- Environmental and Molecular Mutagenesis 2001LIMONENE• mutagenic - Positive mutation assay: Morphological Transform (mouse fbr)
RTECS®- Food and Cosmetics Toxicology 1974LIMONENE• broad systemic - Broad systemic toxicity (rat LD50)
• skin - Primary skin irritant (rabbit )
RTECS®- Food and Cosmetics Toxicology 1978LIMONENE• skin - Primary skin irritant (rabbit )
RTECS®- Toxicologist 2003LIMONENE• skin - Primary skin irritant (rat )

references
government/industry list/academic study reference
Int'l Agency for Research on Cancer (IARC) - CarcinogensIARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures).
RTECS®- Drug Design and Delivery (Chur Harwood Academic) V 1990 [shown for informational purposes only]RTECS®- Drug Design and Delivery (Chur Harwood Academic) V.1- 6,229,1990
RTECS®- Environmental and Molecular Mutagenesis 2001 [shown for informational purposes only]RTECS®- Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 37,231,2001
RTECS®- Food and Cosmetics Toxicology 1974 [shown for informational purposes only]RTECS®- Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. 12,703,1974
RTECS®- Food and Cosmetics Toxicology 1978 [shown for informational purposes only]RTECS®- Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. 16,809,1978
RTECS®- Toxicologist 2003 [shown for informational purposes only]RTECS®- Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- 72,379,2003

"RTECS®" is a United States trademark owned and licensed under authority of the U.S. Government, by and through MDL Information Systems, Inc.